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software:arem [2013/02/21 15:02]
wbiesing created
software:arem [2013/04/16 21:15] (current)
wbiesing
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 ==== AREM ==== ==== AREM ====
-AREM: Aligning ChIP-seq reads by Expectation-Maximization.+ 
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 +==AREM: Aligning ChIP-seq reads by Expectation-Maximization.== 
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 == Description == == Description ==
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 AREM takes the classic peak calling algorithm used in MACS 1.4 (including an empirically optimal tag shift and a locally-adjusted poissonian statistical model for tag enrichment) and adds a component for realigning ambigously mapping reads. ​ A probabilistic model assigns reads to regions that are more likely to be peaks (having higher enrichment). AREM takes the classic peak calling algorithm used in MACS 1.4 (including an empirically optimal tag shift and a locally-adjusted poissonian statistical model for tag enrichment) and adds a component for realigning ambigously mapping reads. ​ A probabilistic model assigns reads to regions that are more likely to be peaks (having higher enrichment).
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 == Paper == == Paper ==
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 For additional information,​ see our paper in RECOMB 2011 (D Newkirk, J Biesinger, A Chon, K Yokomori, X Xie, 2011) or download a copy [[http://​www.ics.uci.edu/​~xhx/​publications/​arem_recomb.pdf|here]]. For additional information,​ see our paper in RECOMB 2011 (D Newkirk, J Biesinger, A Chon, K Yokomori, X Xie, 2011) or download a copy [[http://​www.ics.uci.edu/​~xhx/​publications/​arem_recomb.pdf|here]].
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 == Code == == Code ==
-Regular releases of the software are pushed to the sourceforge page: 
-[[http://​sourceforge.net/​projects/​arem/​]] 
  
-The development version of the code is available at: + 
-[[https://​github.com/​jakebiesinger/​AREM]]+Regular releases of the software are pushed to the sourceforge page: [[http://​sourceforge.net/​projects/​arem/​|http://​sourceforge.net/​projects/​arem/​]] 
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 +The development version of the code is available at: [[https://​github.com/​jakebiesinger/​AREM|https://​github.com/​jakebiesinger/​AREM]] 
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