TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols HUMAN_PWY-841 purine nucleotides de novo biosynthesis 6.39595853135564e-05 -9.65725915354743 37 22 0.0846153846153846 260 907 10632,204,10201,2987,5471,6240,6241,521,3615,506,9551,4832,513,159,2618,654364,29922,10606,10476,4831,3614,498 ATP5L,AK2,NME6,GUK1,PPAT,RRM1,RRM2,ATP5I,IMPDH2,ATP5B,ATP5J2,NME3,ATP5D,ADSS,GART,NME1-NME2,NME7,PAICS,ATP5H,NME2,IMPDH1,ATP5A1 META_PWY-841 superpathway of purine nucleotides de novo biosynthesis I 0.00039418614993073 -7.83868729848813 13 10 0.0384615384615385 260 907 2618,654364,2987,5471,10606,4831,6240,3614,6241,3615 GART,NME1-NME2,GUK1,PPAT,PAICS,NME2,RRM1,IMPDH1,RRM2,IMPDH2 META_PWY-7228 superpathway of guanosine nucleotides de novo biosynthesis I 0.000905202120556492 -7.007352301569 8 7 0.0269230769230769 260 907 3614,6241,654364,3615,2987,6240,4831 IMPDH1,RRM2,NME1-NME2,IMPDH2,GUK1,RRM1,NME2 HUMAN_PWY-7228 guanosine nucleotides de novo biosynthesis 0.00103217324151217 -6.87608875632897 14 10 0.0384615384615385 260 907 654364,29922,2987,10201,6240,4831,3614,6241,3615,4832 NME1-NME2,NME7,GUK1,NME6,RRM1,NME2,IMPDH1,RRM2,IMPDH2,NME3 META_LEU-DEG2-PWY L-leucine degradation I 0.00282575753742938 -5.86897879548856 7 6 0.0230769230769231 260 907 1738,593,594,1629,64087,56922 DLD,BCKDHA,BCKDHB,DBT,MCCC2,MCCC1 HUMAN_PWY-7221 guanosine ribonucleotides de novo biosynthesis 0.00295578490545576 -5.8239910439511 11 8 0.0307692307692308 260 907 3614,654364,3615,29922,2987,10201,4832,4831 IMPDH1,NME1-NME2,IMPDH2,NME7,GUK1,NME6,NME3,NME2 HUMAN_PWY66-5 superpathway of cholesterol biosynthesis 0.00336950086840236 -5.69299065585364 25 14 0.0538461538461538 260 907 1595,3157,3422,6307,4597,2224,1718,1717,6309,10654,9453,2222,3156,10682 CYP51A1,HMGCS1,IDI1,MSMO1,MVD,FDPS,DHCR24,DHCR7,SC5D,PMVK,GGPS1,FDFT1,HMGCR,EBP HUMAN_PWY66-409 superpathway of purine nucleotide salvage 0.00370046527702407 -5.59929671669085 38 19 0.0730769230769231 260 907 10632,204,2987,10201,6240,6241,521,3615,506,9551,4832,513,159,654364,29922,10476,4831,3614,498 ATP5L,AK2,GUK1,NME6,RRM1,RRM2,ATP5I,IMPDH2,ATP5B,ATP5J2,NME3,ATP5D,ADSS,NME1-NME2,NME7,ATP5H,NME2,IMPDH1,ATP5A1 META_PWY66-5 superpathway of cholesterol biosynthesis 0.00425045603385631 -5.46072899971843 23 13 0.05 260 907 1595,3157,3422,6307,4597,2224,1717,6309,10654,9453,2222,3156,10682 CYP51A1,HMGCS1,IDI1,MSMO1,MVD,FDPS,DHCR7,SC5D,PMVK,GGPS1,FDFT1,HMGCR,EBP HUMAN_PWY-5046 2-oxoisovalerate decarboxylation to isobutanoyl-CoA 0.00664161117746916 -5.01440069771866 4 4 0.0153846153846154 260 907 594,1738,593,1629 BCKDHB,DLD,BCKDHA,DBT META_PWY-5046 2-oxoisovalerate decarboxylation to isobutanoyl-CoA 0.00664161117746916 -5.01440069771866 4 4 0.0153846153846154 260 907 1738,593,594,1629 DLD,BCKDHA,BCKDHB,DBT HUMAN_PWY-5659 GDP-mannose biosynthesis 0.00664161117746916 -5.01440069771866 4 4 0.0153846153846154 260 907 5372,4351,5373,29926 PMM1,MPI,PMM2,GMPPA HUMAN_PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis 0.00775268724020686 -4.85971575504568 10 7 0.0269230769230769 260 907 6241,654364,29922,10201,4832,6240,4831 RRM2,NME1-NME2,NME7,NME6,NME3,RRM1,NME2 HUMAN_PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis 0.00775268724020686 -4.85971575504568 10 7 0.0269230769230769 260 907 6241,654364,29922,10201,4832,6240,4831 RRM2,NME1-NME2,NME7,NME6,NME3,RRM1,NME2 META_PWY-7221 guanosine ribonucleotides de novo biosynthesis 0.00863584115149198 -4.75183416025836 6 5 0.0192307692307692 260 907 3614,654364,3615,2987,4831 IMPDH1,NME1-NME2,IMPDH2,GUK1,NME2 HUMAN_PWY-7511 protein ubiquitylation 0.0125817508432404 -4.37550786066585 28 14 0.0538461538461538 260 907 7323,29089,7317,7336,55293,55284,79876,51465,51619,55585,27338,54926,55236,54476 UBE2D3,UBE2T,UBA1,UBE2V2,UEVLD,UBE2W,UBA5,UBE2J1,UBE2D4,UBE2Q1,UBE2S,UBE2R2,UBA6,RNF216 HUMAN_PWY-7224 purine deoxyribonucleosides salvage 0.0161472663260502 -4.1260045113777 11 7 0.0269230769230769 260 907 654364,29922,2987,10201,1716,4832,4831 NME1-NME2,NME7,GUK1,NME6,DGUOK,NME3,NME2 META_PWY66-398 TCA cycle III (animals) 0.018142546757845 -4.00949544956051 16 9 0.0346153846153846 260 907 50,8802,6391,4191,2271,1431,4967,1743,6392 ACO2,SUCLG1,SDHC,MDH2,FH,CS,OGDH,DLST,SDHD HUMAN_PWY66-398 TCA cycle 0.018142546757845 -4.00949544956051 16 9 0.0346153846153846 260 907 50,8802,6391,4191,2271,1431,4967,1743,6392 ACO2,SUCLG1,SDHC,MDH2,FH,CS,OGDH,DLST,SDHD HUMAN_PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis 0.0230961053071669 -3.76809127709055 14 8 0.0307692307692308 260 907 654364,29922,10201,1854,6240,4831,6241,4832 NME1-NME2,NME7,NME6,DUT,RRM1,NME2,RRM2,NME3 HUMAN_PWY-5328 superpathway of methionine degradation 0.0230961053071669 -3.76809127709055 14 8 0.0307692307692308 260 907 27430,6821,4594,594,593,2805,1738,1629 MAT2B,SUOX,MUT,BCKDHB,BCKDHA,GOT1,DLD,DBT META_PWY-5328 superpathway of L-methionine salvage and degradation 0.0230961053071669 -3.76809127709055 14 8 0.0307692307692308 260 907 6821,4594,593,594,2805,1738,4548,1629 SUOX,MUT,BCKDHA,BCKDHB,GOT1,DLD,MTR,DBT META_PWY-5130 2-oxobutanoate degradation I 0.0231610501869976 -3.76528328244366 7 5 0.0192307692307692 260 907 4594,1738,593,594,1629 MUT,DLD,BCKDHA,BCKDHB,DBT HUMAN_PWY-5130 2-oxobutanoate degradation 0.0231610501869976 -3.76528328244366 7 5 0.0192307692307692 260 907 4594,594,1738,593,1629 MUT,BCKDHB,DLD,BCKDHA,DBT META_PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 0.0233619319238762 -3.75664742222102 3 3 0.0115384615384615 260 907 4967,1738,1743 OGDH,DLD,DLST HUMAN_PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 0.0233619319238762 -3.75664742222102 3 3 0.0115384615384615 260 907 4967,1743,1738 OGDH,DLST,DLD HUMAN_PWY-7283 wybutosine biosynthesis 0.0233619319238762 -3.75664742222102 3 3 0.0115384615384615 260 907 127253,55253,9836 TYW3,TYW1,LCMT2 META_PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I 0.0256764835221522 -3.66217974403239 5 4 0.0153846153846154 260 907 6241,654364,6240,4831 RRM2,NME1-NME2,RRM1,NME2 META_VALDEG-PWY L-valine degradation I 0.0256764835221522 -3.66217974403239 5 4 0.0153846153846154 260 907 1738,593,594,1629 DLD,BCKDHA,BCKDHB,DBT META_PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis 0.0256764835221522 -3.66217974403239 5 4 0.0153846153846154 260 907 6241,654364,6240,4831 RRM2,NME1-NME2,RRM1,NME2 HUMAN_PWY-5910 superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) 0.0294005828158945 -3.52674078116411 12 7 0.0269230769230769 260 907 3157,3422,9453,10654,4597,2224,3156 HMGCS1,IDI1,GGPS1,PMVK,MVD,FDPS,HMGCR META_PWY-5910 superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) 0.0294005828158945 -3.52674078116411 12 7 0.0269230769230769 260 907 3157,3422,9453,10654,4597,2224,3156 HMGCS1,IDI1,GGPS1,PMVK,MVD,FDPS,HMGCR HUMAN_PWY66-4 cholesterol biosynthesis III (via desmosterol) 0.0484142793220208 -3.02796048145707 13 7 0.0269230769230769 260 907 1595,1717,6309,6307,1718,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,DHCR24,FDFT1,EBP HUMAN_PWY66-341 cholesterol biosynthesis I 0.0484142793220208 -3.02796048145707 13 7 0.0269230769230769 260 907 1595,1717,6309,6307,1718,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,DHCR24,FDFT1,EBP HUMAN_PWY66-3 cholesterol biosynthesis II (via 24,25-dihydrolanosterol) 0.0484142793220208 -3.02796048145707 13 7 0.0269230769230769 260 907 1595,1717,6309,6307,1718,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,DHCR24,FDFT1,EBP META_PWY66-409 superpathway of purine nucleotide salvage 0.0484142793220208 -3.02796048145707 13 7 0.0269230769230769 260 907 3614,6241,654364,3615,2987,6240,4831 IMPDH1,RRM2,NME1-NME2,IMPDH2,GUK1,RRM1,NME2 META_PWY66-428 L-threonine degradation V 0.0597577682643173 -2.81745608382953 6 4 0.0153846153846154 260 907 594,593,1738,1629 BCKDHB,BCKDHA,DLD,DBT META_PWY-7229 superpathway of adenosine nucleotides de novo biosynthesis I 0.0597577682643173 -2.81745608382953 6 4 0.0153846153846154 260 907 6241,654364,6240,4831 RRM2,NME1-NME2,RRM1,NME2 META_ILEUDEG-PWY L-isoleucine degradation I 0.0597577682643173 -2.81745608382953 6 4 0.0153846153846154 260 907 1738,593,594,1629 DLD,BCKDHA,BCKDHB,DBT HUMAN_PWY66-428 threonine degradation 0.0597577682643173 -2.81745608382953 6 4 0.0153846153846154 260 907 594,593,1738,1629 BCKDHB,BCKDHA,DLD,DBT META_PWY66-341 cholesterol biosynthesis I 0.0628991229198732 -2.76622305941313 11 6 0.0230769230769231 260 907 1595,1717,6309,6307,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,FDFT1,EBP META_PWY66-4 cholesterol biosynthesis III (via desmosterol) 0.0628991229198732 -2.76622305941313 11 6 0.0230769230769231 260 907 1595,1717,6309,6307,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,FDFT1,EBP HUMAN_LEU-DEG2-PWY leucine degradation 0.0628991229198732 -2.76622305941313 11 6 0.0230769230769231 260 907 594,1738,593,1629,64087,56922 BCKDHB,DLD,BCKDHA,DBT,MCCC2,MCCC1 META_PWY66-3 cholesterol biosynthesis II (via 24,25-dihydrolanosterol) 0.0628991229198732 -2.76622305941313 11 6 0.0230769230769231 260 907 1595,1717,6309,6307,2222,10682 CYP51A1,DHCR7,SC5D,MSMO1,FDFT1,EBP HUMAN_PWY-5667 CDP-diacylglycerol biosynthesis 0.0629901526586399 -2.76477687181353 19 9 0.0346153846153846 260 907 10162,2710,57678,10555,253558,56895,84803,1040,10554 LPCAT3,GK,GPAM,AGPAT2,LCLAT1,AGPAT4,GPAT3,CDS1,AGPAT1 HUMAN_PWY-7219 adenosine ribonucleotides de novo biosynthesis 0.0629901526586399 -2.76477687181353 19 9 0.0346153846153846 260 907 159,10632,204,10476,521,506,498,9551,513 ADSS,ATP5L,AK2,ATP5H,ATP5I,ATP5B,ATP5A1,ATP5J2,ATP5D META_PWY66-423 fructose 2,6-bisphosphate biosynthesis 0.0735228941628363 -2.61015843605613 4 3 0.0115384615384615 260 907 5209,57103,5208 PFKFB3,TIGAR,PFKFB2 HUMAN_PWY-5123 trans, trans-farnesyl diphosphate biosynthesis 0.0735228941628363 -2.61015843605613 4 3 0.0115384615384615 260 907 3422,9453,2224 IDI1,GGPS1,FDPS META_PWY-5123 trans, trans-farnesyl diphosphate biosynthesis 0.0735228941628363 -2.61015843605613 4 3 0.0115384615384615 260 907 3422,9453,2224 IDI1,GGPS1,FDPS META_PWY-7181 pyrimidine deoxyribonucleosides degradation 0.0735228941628363 -2.61015843605613 4 3 0.0115384615384615 260 907 9997,1890,7378 SCO2,TYMP,UPP1 HUMAN_PWY66-423 fructose 2,6-bisphosphate synthesis 0.0735228941628363 -2.61015843605613 4 3 0.0115384615384615 260 907 5209,57103,5208 PFKFB3,TIGAR,PFKFB2 HUMAN_PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP 0.073732453336975 -2.60731223292444 14 7 0.0269230769230769 260 907 6241,654364,29922,10201,4832,6240,4831 RRM2,NME1-NME2,NME7,NME6,NME3,RRM1,NME2 META_CHOLINE-BETAINE-ANA-PWY choline degradation I 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 501,55349 ALDH7A1,CHDH HUMAN_PWY-6121 5-aminoimidazole ribonucleotide biosynthesis 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 2618,5471 GART,PPAT META_PWY-7437 protein O-[N-acetyl]-glucosylation 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 10724,8473 MGEA5,OGT META_PWY66-366 flavin biosynthesis IV (mammalian) 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 80308,55312 FLAD1,RFK HUMAN_PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 127253,55253 TYW3,TYW1 META_PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 2618,5471 GART,PPAT HUMAN_PWY-5905 hypusine biosynthesis 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 83475,1725 DOHH,DHPS META_PWY-7511 protein ubiquitylation 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 7317,55284 UBA1,UBE2W HUMAN_PWY-7437 protein O-[N-acetyl]-glucosylation 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 10724,8473 MGEA5,OGT META_PROUT-PWY L-proline degradation 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 8659,5625 ALDH4A1,PRODH HUMAN_ASPARAGINE-BIOSYNTHESIS asparagine biosynthesis 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 2805,440 GOT1,ASNS HUMAN_CHOLINE-BETAINE-ANA-PWY choline degradation 0.0819478619809934 -2.50167206344327 2 2 0.00769230769230769 260 907 501,55349 ALDH7A1,CHDH HUMAN_PWY-0 putrescine degradation III 0.0822498913707335 -2.49799321005809 9 5 0.0192307692307692 260 907 4128,221,112483,224,6303 MAOA,ALDH3B1,SAT2,ALDH3A2,SAT1 HUMAN_PWY-7205 CMP phosphorylation 0.0822498913707335 -2.49799321005809 9 5 0.0192307692307692 260 907 654364,29922,10201,4832,4831 NME1-NME2,NME7,NME6,NME3,NME2 META_PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I 0.0822498913707335 -2.49799321005809 9 5 0.0192307692307692 260 907 6241,654364,1854,6240,4831 RRM2,NME1-NME2,DUT,RRM1,NME2 HUMAN_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis 0.0866873361401085 -2.44544747114555 20 9 0.0346153846153846 260 907 654364,29922,10201,1854,6240,4831,6241,7372,4832 NME1-NME2,NME7,NME6,DUT,RRM1,NME2,RRM2,UMPS,NME3 HUMAN_PWY66-407 superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle 0.0954223089275953 -2.34944288166445 38 15 0.0576923076923077 260 907 5160,50,8802,5230,669,6391,4191,226,2271,1431,5224,4967,1738,1743,6392 PDHA1,ACO2,SUCLG1,PGK1,BPGM,SDHC,MDH2,ALDOA,FH,CS,PGAM2,OGDH,DLD,DLST,SDHD META_PWY-7224 purine deoxyribonucleosides salvage 0.108553392367846 -2.22051313148475 7 4 0.0153846153846154 260 907 654364,2987,1716,4831 NME1-NME2,GUK1,DGUOK,NME2 HUMAN_PWY-6369 inositol pyrophosphates biosynthesis 0.108553392367846 -2.22051313148475 7 4 0.0153846153846154 260 907 64768,51447,9807,253430 IPPK,IP6K2,IP6K1,IPMK META_PWY-6369 inositol pyrophosphates biosynthesis 0.108553392367846 -2.22051313148475 7 4 0.0153846153846154 260 907 64768,51447,9807,253430 IPPK,IP6K2,IP6K1,IPMK HUMAN_PWY-6352 3-phosphoinositide biosynthesis 0.118225323995087 -2.1351629499604 27 11 0.0423076923076923 260 907 8396,5289,5298,5296,30849,22908,8503,138429,200576,8394,55361 PIP4K2B,PIK3C3,PI4KB,PIK3R2,PIK3R4,SACM1L,PIK3R3,PIP5KL1,PIKFYVE,PIP5K1A,PI4K2A META_PWY-922 mevalonate pathway I 0.127101672509609 -2.06276794186773 10 5 0.0192307692307692 260 907 3157,3422,10654,4597,3156 HMGCS1,IDI1,PMVK,MVD,HMGCR HUMAN_PWY-922 mevalonate pathway 0.127101672509609 -2.06276794186773 10 5 0.0192307692307692 260 907 3157,3422,10654,4597,3156 HMGCS1,IDI1,PMVK,MVD,HMGCR HUMAN_PWY-7197 pyrimidine deoxyribonucleotide phosphorylation 0.127101672509609 -2.06276794186773 10 5 0.0192307692307692 260 907 654364,29922,10201,4832,4831 NME1-NME2,NME7,NME6,NME3,NME2 HUMAN_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis 0.137526277626337 -1.98394027012498 13 6 0.0230769230769231 260 907 7372,654364,29922,10201,4832,4831 UMPS,NME1-NME2,NME7,NME6,NME3,NME2 HUMAN_PWY66-399 gluconeogenesis 0.143399101423567 -1.94212361705963 16 7 0.0269230769230769 260 907 5224,5091,92579,5230,669,4191,226 PGAM2,PC,G6PC3,PGK1,BPGM,MDH2,ALDOA META_PWY66-399 gluconeogenesis III 0.143399101423567 -1.94212361705963 16 7 0.0269230769230769 260 907 5224,5091,92579,5230,669,4191,226 PGAM2,PC,G6PC3,PGK1,BPGM,MDH2,ALDOA META_PWY-5667 CDP-diacylglycerol biosynthesis I 0.145292510125759 -1.92900625738932 5 3 0.0115384615384615 260 907 10555,56895,10554 AGPAT2,AGPAT4,AGPAT1 HUMAN_PWY-7181 pyrimidine deoxyribonucleosides degradation 0.145292510125759 -1.92900625738932 5 3 0.0115384615384615 260 907 9997,1890,7378 SCO2,TYMP,UPP1 META_CITRULBIO-PWY L-citrulline biosynthesis 0.145292510125759 -1.92900625738932 5 3 0.0115384615384615 260 907 384,5625,5832 ARG2,PRODH,ALDH18A1 META_PWY-4061 glutathione-mediated detoxification I 0.145292510125759 -1.92900625738932 5 3 0.0115384615384615 260 907 56267,2954,883 CCBL2,GSTZ1,CCBL1 HUMAN_PWY-2201 folate transformations I 0.169656357217554 -1.77398031590724 8 4 0.0153846153846154 260 907 10797,400410,6470,4548 MTHFD2,ST20,SHMT1,MTR HUMAN_PWY-7176 UTP and CTP de novo biosynthesis 0.180603797167809 -1.71144961292787 11 5 0.0192307692307692 260 907 654364,29922,10201,4832,4831 NME1-NME2,NME7,NME6,NME3,NME2 META_ASPARAGINE-DEG1-PWY-1 L-asparagine degradation III (mammalian) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 2805,175 GOT1,AGA META_PWY-7606 docosahexaenoate biosynthesis III (mammals) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 9415,60481 FADS2,ELOVL5 META_MALATE-ASPARTATE-SHUTTLE-PWY L-aspartate degradation II 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 2805,4191 GOT1,MDH2 META_PWY6666-2 dopamine degradation 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 4128,224 MAOA,ALDH3A2 HUMAN_OXIDATIVEPENT-PWY-1 pentose phosphate pathway (oxidative branch) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 25796,5226 PGLS,PGD META_ARGASEDEG-PWY L-arginine degradation I (arginase pathway) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 384,8659 ARG2,ALDH4A1 HUMAN_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 64768,253430 IPPK,IPMK META_PWY-7527 L-methionine salvage cycle III 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 883,4507 CCBL1,MTAP META_PWY-7049 icosapentaenoate biosynthesis II (metazoa) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 9415,60481 FADS2,ELOVL5 META_OXIDATIVEPENT-PWY pentose phosphate pathway (oxidative branch) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 25796,5226 PGLS,PGD HUMAN_PWY-7606 docosahexaenoate biosynthesis III (mammals) 0.199119722094752 -1.61384901659095 3 2 0.00769230769230769 260 907 9415,60481 FADS2,ELOVL5 HUMAN_PENTOSE-P-PWY pentose phosphate pathway 0.2308272519881 -1.4660856751137 6 3 0.0115384615384615 260 907 25796,22934,5226 PGLS,RPIA,PGD HUMAN_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 0.238628416289694 -1.43284768047634 15 6 0.0230769230769231 260 907 51763,64768,3633,3636,8867,253430 INPP5K,IPPK,INPP5B,INPPL1,SYNJ1,IPMK META_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 0.238628416289694 -1.43284768047634 15 6 0.0230769230769231 260 907 51763,64768,3633,3636,8867,253430 INPP5K,IPPK,INPP5B,INPPL1,SYNJ1,IPMK HUMAN_PWY-7200 superpathway of pyrimidine deoxyribonucleoside salvage 0.238628416289694 -1.43284768047634 15 6 0.0230769230769231 260 907 654364,7083,29922,10201,4832,4831 NME1-NME2,TK1,NME7,NME6,NME3,NME2 HUMAN_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS dolichyl-diphosphooligosaccharide biosynthesis 0.23958152989582 -1.42886150295838 9 4 0.0153846153846154 260 907 10195,1798,79868,79053 ALG3,DPAGT1,ALG13,ALG8 META_PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP 0.23958152989582 -1.42886150295838 9 4 0.0153846153846154 260 907 6241,654364,6240,4831 RRM2,NME1-NME2,RRM1,NME2 HUMAN_PWY-7527 methionine salvage cycle III 0.23958152989582 -1.42886150295838 9 4 0.0153846153846154 260 907 58478,27430,4507,84245 ENOPH1,MAT2B,MTAP,MRI1 HUMAN_VALDEG-PWY valine degradation 0.240751035842577 -1.42399192574794 12 5 0.0192307692307692 260 907 4329,594,1738,593,1629 ALDH6A1,BCKDHB,DLD,BCKDHA,DBT META_PWY-6352 3-phosphoinositide biosynthesis 0.268735434745294 -1.31402789730552 25 9 0.0346153846153846 260 907 5289,5298,5296,30849,22908,8503,200576,8394,55361 PIK3C3,PI4KB,PIK3R2,PIK3R4,SACM1L,PIK3R3,PIKFYVE,PIP5K1A,PI4K2A META_PWY-6756 S-methyl-5'-thioadenosine degradation II 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 4507 MTAP META_PWY-5329 L-cysteine degradation III 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2805 GOT1 META_ASPARTATESYN-PWY L-aspartate biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2805 GOT1 HUMAN_PWY-5148 acyl-CoA hydrolysis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 23597 ACOT9 HUMAN_PWY-6399 melatonin degradation II 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 4128 MAOA META_PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 9054 NFS1 META_PWY-5905 hypusine biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 83475 DOHH HUMAN_PWY-6898 thiamin salvage III 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 27010 TPK1 META_PWY-5512 UDP-N-acetyl-D-galactosamine biosynthesis I 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2582 GALE HUMAN_PWY0-522 lipoate salvage 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 51601 LIPT1 HUMAN_PWY-5120 geranylgeranyldiphosphate biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 9453 GGPS1 META_PWY-5326 sulfite oxidation IV 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 6821 SUOX META_PWY66-389 phytol degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-5512 UDP-N-acetyl-D-galactosamine biosynthesis I 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2582 GALE META_PWY-6012-1 acyl carrier protein metabolism II (mammalian) 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 60496 AASDHPPT HUMAN_PROUT-PWY proline degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 8659 ALDH4A1 HUMAN_ARGSPECAT-PWY spermine biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 6611 SMS META_PWY-5120 geranylgeranyl diphosphate biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 9453 GGPS1 HUMAN_PWY-7592 arachidonate biosynthesis III (metazoa) 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 60481 ELOVL5 HUMAN_PWY-5326 sulfite oxidation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 6821 SUOX HUMAN_PWY-4101 sorbitol degradation I 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 6652 SORD META_PWY-7592 arachidonate biosynthesis III (metazoa) 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 60481 ELOVL5 HUMAN_PWY-6756 S-methyl-5'-thioadenosine degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 4507 MTAP HUMAN_PWY66-366 flavin biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 80308 FLAD1 META_PWY-7344 UDP-D-galactose biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2582 GALE META_ARGSPECAT-PWY spermine biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 6611 SMS HUMAN_MANNCAT-PWY D-mannose degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 4351 MPI META_PWY-5172 acetyl-CoA biosynthesis III (from citrate) 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 47 ACLY HUMAN_PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 9054 NFS1 HUMAN_PWY-5329 L-cysteine degradation II 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 2805 GOT1 META_PWY0-1021 L-alanine biosynthesis III 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 9054 NFS1 HUMAN_SERSYN-PWY serine biosynthesis (phosphorylated route) 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 51699 VPS29 HUMAN_PWY-5172 acetyl-CoA biosynthesis from citrate 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 47 ACLY HUMAN_PWY66-389 phytol degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 883 CCBL1 HUMAN_PWY-2161B glutamate removal from folates 0.286659316427991 -1.24946081909889 1 1 0.00384615384615385 260 907 8836 GGH META_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis 0.305266509728484 -1.18657008152931 13 5 0.0192307692307692 260 907 6241,654364,1854,6240,4831 RRM2,NME1-NME2,DUT,RRM1,NME2 HUMAN_PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 0.305266509728484 -1.18657008152931 13 5 0.0192307692307692 260 907 51763,3633,3636,8867,3613 INPP5K,INPP5B,INPPL1,SYNJ1,IMPA2 META_PWY-5920 superpathway of heme biosynthesis from glycine 0.322532646704342 -1.13155091777875 7 3 0.0115384615384615 260 907 3145,210,5498 HMBS,ALAD,PPOX HUMAN_PWY66-374 C20 prostanoid biosynthesis 0.322532646704342 -1.13155091777875 7 3 0.0115384615384615 260 907 5743,10728,80142 PTGS2,PTGES3,PTGES2 META_PWY66-374 C20 prostanoid biosynthesis 0.322532646704342 -1.13155091777875 7 3 0.0115384615384615 260 907 5743,10728,80142 PTGS2,PTGES3,PTGES2 HUMAN_PWY66-414 superpathway of choline degradation to L-serine 0.322532646704342 -1.13155091777875 7 3 0.0115384615384615 260 907 501,55349,6470 ALDH7A1,CHDH,SHMT1 HUMAN_PWY-5920 heme biosynthesis 0.322532646704342 -1.13155091777875 7 3 0.0115384615384615 260 907 3145,210,5498 HMBS,ALAD,PPOX META_PWY-6823 molybdenum cofactor biosynthesis 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 27304,9054 MOCS3,NFS1 META_PWY-5189 tetrapyrrole biosynthesis II (from glycine) 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 3145,210 HMBS,ALAD HUMAN_PWY6666-2 dopamine degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 4128,224 MAOA,ALDH3A2 META_PWY-6405 Rapoport-Luebering glycolytic shunt 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 5224,669 PGAM2,BPGM META_PWY-7205 CMP phosphorylation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 654364,4831 NME1-NME2,NME2 HUMAN_PWY-6117 spermine and spermidine degradation I 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 112483,6303 SAT2,SAT1 HUMAN_PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 58478,84245 ENOPH1,MRI1 HUMAN_PWY-2161 folate polyglutamylation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 6470,2356 SHMT1,FPGS META_PWY-3781 aerobic respiration I (cytochrome c) 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 6391,6392 SDHC,SDHD META_PYRUVDEHYD-PWY pyruvate decarboxylation to acetyl CoA 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 5160,1738 PDHA1,DLD HUMAN_ASPARAGINE-DEG1-PWY-1 asparagine degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 2805,175 GOT1,AGA HUMAN_PWY-6755 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 58478,84245 ENOPH1,MRI1 HUMAN_SER-GLYSYN-PWY serine and glycine biosynthesis 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 6470,51699 SHMT1,VPS29 HUMAN_MALATE-ASPARTATE-SHUTTLE-PWY malate-aspartate shuttle 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 2805,4191 GOT1,MDH2 HUMAN_PWY-5874 heme degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 3163,645 HMOX2,BLVRB HUMAN_PWY-5872 ubiquinol-10 biosynthesis 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 57107,51004 PDSS2,COQ6 HUMAN_PWY-5189 tetrapyrrole biosynthesis 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 3145,210 HMBS,ALAD HUMAN_PWY-6823 molybdenum cofactor biosynthesis 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 27304,9054 MOCS3,NFS1 HUMAN_PWY-6307 tryptophan degradation via tryptamine 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 224,10327 ALDH3A2,AKR1A1 META_PWY-5872 ubiquinol-10 biosynthesis (eukaryotic) 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 57107,51004 PDSS2,COQ6 HUMAN_PWY-4261 glycerol degradation 0.324716550030021 -1.12480263095355 4 2 0.00769230769230769 260 907 2710,2820 GK,GPD2 META_PWY-5004 superpathway of L-citrulline metabolism 0.391119132527438 -0.938743078633418 11 4 0.0153846153846154 260 907 384,5625,1373,5832 ARG2,PRODH,CPS1,ALDH18A1 META_PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 0.391119132527438 -0.938743078633418 11 4 0.0153846153846154 260 907 51763,3633,8867,3613 INPP5K,INPP5B,SYNJ1,IMPA2 HUMAN_PWY-6371 superpathway of inositol phosphate compounds 0.428293175732025 -0.847947327870835 66 20 0.0769230769230769 260 907 5289,3636,9807,90809,30849,51447,3633,8394,8867,55361,8396,51763,64768,5298,5296,253430,22908,8503,138429,200576 PIK3C3,INPPL1,IP6K1,TMEM55B,PIK3R4,IP6K2,INPP5B,PIP5K1A,SYNJ1,PI4K2A,PIP4K2B,INPP5K,IPPK,PI4KB,PIK3R2,IPMK,SACM1L,PIK3R3,PIP5KL1,PIKFYVE HUMAN_PWY-6364 D-myo-inositol (1,3,4)-trisphosphate biosynthesis 0.438497943020534 -0.824400158126092 15 5 0.0192307692307692 260 907 51763,3633,3636,8867,253430 INPP5K,INPP5B,INPPL1,SYNJ1,IPMK META_PWY-6364 D-myo-inositol (1,3,4)-trisphosphate biosynthesis 0.438497943020534 -0.824400158126092 15 5 0.0192307692307692 260 907 51763,3633,3636,8867,253430 INPP5K,INPP5B,INPPL1,SYNJ1,IPMK META_PWY-6313 serotonin degradation 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 4128,224 MAOA,ALDH3A2 HUMAN_PYRUVDEHYD-PWY pyruvate decarboxylation to acetyl CoA 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 5160,1738 PDHA1,DLD META_PWY-6074 zymosterol biosynthesis 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 1595,6307 CYP51A1,MSMO1 META_PWY-4984 urea cycle 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 384,1373 ARG2,CPS1 META_PWY-7197 pyrimidine deoxyribonucleotide phosphorylation 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 654364,4831 NME1-NME2,NME2 HUMAN_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation 0.444332576634498 -0.811181950471117 5 2 0.00769230769230769 260 907 3614,3615 IMPDH1,IMPDH2 HUMAN_ILEUDEG-PWY isoleucine degradation 0.466303180871149 -0.762919253678906 12 4 0.0153846153846154 260 907 594,1738,593,1629 BCKDHB,DLD,BCKDHA,DBT HUMAN_PWY-4061 glutathione-mediated detoxification 0.474824824950248 -0.744809332545521 19 6 0.0230769230769231 260 907 56267,8836,2954,373156,883,4259 CCBL2,GGH,GSTZ1,GSTK1,CCBL1,MGST3 META_PWY-6368 3-phosphoinositide degradation 0.474824824950248 -0.744809332545521 19 6 0.0230769230769231 260 907 22908,51763,3633,3636,8867,90809 SACM1L,INPP5K,INPP5B,INPPL1,SYNJ1,TMEM55B META_PWY-6358 superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism 0.474824824950248 -0.744809332545521 19 6 0.0230769230769231 260 907 51763,3633,3636,8867,3613,253430 INPP5K,INPP5B,INPPL1,SYNJ1,IMPA2,IPMK HUMAN_PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 253430 IPMK HUMAN_PWY-6405 Rapoport-Luebering glycolytic shunt 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 669 BPGM HUMAN_PWY-6129 dolichol and dolichyl phosphate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 79947 DHDDS META_PWY-6117 spermine and spermidine degradation I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 6303 SAT1 META_PWY-4041 gamma-glutamyl cycle 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2729 GCLC META_PWY66-394 aspirin triggered resolvin E biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 META_PWY-6613 tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2618 GART HUMAN_PWY-6118 glycerol-3-phosphate shuttle 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2820 GPD2 HUMAN_PROSYN-PWY proline biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5832 ALDH18A1 META_PWY0-1295 pyrimidine ribonucleosides degradation 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 7378 UPP1 META_PWY-6688 thyronamine and iodothyronamine metabolism 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 1734 DIO2 HUMAN_BETA-ALA-DEGRADATION-I-PWY beta-alanine degradation 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 4329 ALDH6A1 HUMAN_PWY-4821 UDP-D-xylose and UDP-D-glucuronate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 7358 UGDH HUMAN_PWY6666-1 anandamide degradation 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 158584 FAAH2 META_PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 253430 IPMK META_PWY-6118 glycerol-3-phosphate shuttle 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2820 GPD2 HUMAN_PWY-5686 UMP biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 7372 UMPS HUMAN_PWY-5481 lactate fermentation (reoxidation of cytosolic NADH) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 3939 LDHA HUMAN_PWY66-14 MAP kinase cascade 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5604 MAP2K1 META_PLPSAL-PWY pyridoxal 5'-phosphate salvage I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 55163 PNPO HUMAN_ASPARTATESYN-PWY aspartate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2805 GOT1 HUMAN_PWY0-1275 lipoate biosynthesis and incorporation 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 51601 LIPT1 HUMAN_GLUTAMINDEG-PWY glutamine degradation/glutamate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2744 GLS HUMAN_PWY-6688 thyronamine and iodothyronamine metabolism 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 1734 DIO2 HUMAN_PWY-5386 methylglyoxal degradation I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2739 GLO1 META_PWY-5806 all-trans-decaprenyl diphosphate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 57107 PDSS2 META_PWY-6124 inosine-5'-phosphate biosynthesis II 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 10606 PAICS META_PWY66-395 aspirin triggered resolvin D biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 HUMAN_PWY66-393 aspirin-triggered lipoxin biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 META_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 6470 SHMT1 HUMAN_PWY-6124 inosine-5'-phosphate biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 10606 PAICS HUMAN_PWY-6613 tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2618 GART HUMAN_PWY-4041 gamma-glutamyl cycle 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 55748 CNDP2 META_LYSINE-DEG1-PWY L-lysine degradation XI (mammalian) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 501 ALDH7A1 HUMAN_PWY-5670 epoxysqualene biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2222 FDFT1 HUMAN_PWY66-394 aspirin triggered resolvin E biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 HUMAN_PWY66-395 aspirin triggered resolvin D biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 HUMAN_PWY-6012-1 acyl carrier protein metabolism 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 60496 AASDHPPT HUMAN_PWY-6482 diphthamide biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 89978 DPH6 META_PROSYN-PWY L-proline biosynthesis I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5832 ALDH18A1 HUMAN_CYSTEINE-DEG-PWY L-cysteine degradation I 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2805 GOT1 META_PWY66-393 aspirin-triggered lipoxin biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 5743 PTGS2 HUMAN_LYSINE-DEG1-PWY lysine degradation I (saccharopine pathway) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 501 ALDH7A1 META_PWY-5670 epoxysqualene biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 2222 FDFT1 HUMAN_PWY-6260 thyroid hormone metabolism I (via deiodination) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 1734 DIO2 META_PWY-6307 L-tryptophan degradation X (mammalian, via tryptamine) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY66-388 fatty acid alpha-oxidation III 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY-5453 methylglyoxal degradation III 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 231 AKR1B1 HUMAN_GLYSYN-PWY glycine/serine biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 6470 SHMT1 HUMAN_PWY-6 GDP-L-fucose biosynthesis II (from L-fucose) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 197258 FUK HUMAN_PWY-5137 fatty acid beta-oxidation (unsaturated, odd number) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 1632 ECI1 META_PWY-7343 UDP-glucose biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 7360 UGP2 HUMAN_PWY-2301 myo-inositol de novo biosynthesis 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 3613 IMPA2 META_PWY-6260 thyroid hormone metabolism I (via deiodination) 0.491370770867248 -0.710556302008776 2 1 0.00384615384615385 260 907 1734 DIO2 HUMAN_PWY-6353 purine nucleotides degradation 0.501596865649197 -0.689958538388697 9 3 0.0115384615384615 260 907 3614,3615,57665 IMPDH1,IMPDH2,RDH14 META_PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine) 0.501596865649197 -0.689958538388697 9 3 0.0115384615384615 260 907 56267,883,8942 CCBL2,CCBL1,KYNU HUMAN_PWY-6358 superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism 0.532468106259301 -0.630232277541026 20 6 0.0230769230769231 260 907 51763,3633,3636,8867,3613,253430 INPP5K,INPP5B,INPPL1,SYNJ1,IMPA2,IPMK HUMAN_PWY-6368 3-phosphoinositide degradation 0.532468106259301 -0.630232277541026 20 6 0.0230769230769231 260 907 22908,51763,3633,3636,8867,90809 SACM1L,INPP5K,INPP5B,INPPL1,SYNJ1,TMEM55B HUMAN_PWY3DJ-12 ceramide de novo biosynthesis 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 10558,9517 SPTLC1,SPTLC2 HUMAN_PWY3O-450 phosphatidylcholine biosynthesis 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 5130,1119 PCYT1A,CHKA META_PWY3DJ-12 ceramide de novo biosynthesis 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 10558,9517 SPTLC1,SPTLC2 HUMAN_PWY-6074 zymosterol biosynthesis 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 1595,6307 CYP51A1,MSMO1 META_PWY-7176 UTP and CTP de novo biosynthesis 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 654364,4831 NME1-NME2,NME2 META_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 3614,3615 IMPDH1,IMPDH2 META_PWY-7277 sphingolipid biosynthesis (mammals) 0.551085238959275 -0.595865783138153 6 2 0.00769230769230769 260 907 10558,9517 SPTLC1,SPTLC2 META_PWY-7200 superpathway of pyrimidine deoxyribonucleoside salvage 0.58175205029148 -0.541710952454455 10 3 0.0115384615384615 260 907 654364,7083,4831 NME1-NME2,TK1,NME2 HUMAN_TRIGLSYN-PWY triacylglycerol biosynthesis 0.606254107146018 -0.500456062079547 25 7 0.0269230769230769 260 907 10162,57678,10555,253558,56895,84803,10554 LPCAT3,GPAM,AGPAT2,LCLAT1,AGPAT4,GPAT3,AGPAT1 HUMAN_PROPIONMET-PWY propionyl-CoA degradation 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 4594 MUT META_ADENOSYLHOMOCYSCAT-PWY L-methionine salvage from L-homocysteine 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 4548 MTR HUMAN_PWY-5331 taurine biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 84890 ADO META_PWY-5664 tetrahydrobiopterin biosynthesis II 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5805 PTS META_PROPIONMET-PWY propanoyl CoA degradation I 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 4594 MUT META_PWY-5331 taurine biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 84890 ADO META_ARGININE-SYN4-PWY L-ornithine de novo biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5832 ALDH18A1 HUMAN_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 253430 IPMK HUMAN_PWY0-1295 pyrimidine ribonucleosides degradation 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 7378 UPP1 HUMAN_PWY66-388 fatty acid alpha-oxidation III 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY-6000 gamma-linolenate biosynthesis II (animals) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 9415 FADS2 META_GLYCLEAV-PWY glycine cleavage 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 1738 DLD HUMAN_ADENOSYLHOMOCYSCAT-PWY methionine salvage 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 4548 MTR META_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 253430 IPMK HUMAN_METHIONINE-DEG1-PWY methionine degradation 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 27430 MAT2B META_PWY-0 putrescine degradation III 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY-5451 acetone degradation I (to methylglyoxal) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 231 AKR1B1 META_PWY-5663 tetrahydrobiopterin biosynthesis I 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5805 PTS HUMAN_PWY66-385 dTMP de novo biosynthesis (mitochondrial) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 200895 DHFRL1 HUMAN_PWY-5663 tetrahydrobiopterin de novo biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5805 PTS META_PWY-2301 myo-inositol biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 3613 IMPA2 META_PHENYLALANINE-DEG1-PWY L-phenylalanine degradation I (aerobic) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 84105 PCBD2 META_HEME-BIOSYNTHESIS-II heme biosynthesis I (aerobic) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5498 PPOX META_PWY66-425 L-lysine degradation II (L-pipecolate pathway) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 501 ALDH7A1 HUMAN_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 22934 RPIA HUMAN_ARGININE-SYN4-PWY ornithine de novo biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5832 ALDH18A1 HUMAN_GLYCLEAV-PWY glycine cleavage 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 1738 DLD META_PWY-7466 acetone degradation III (to propane-1,2-diol) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 231 AKR1B1 HUMAN_HEME-BIOSYNTHESIS-II heme biosynthesis from uroporphyrinogen-III I 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 5498 PPOX HUMAN_PHENYLALANINE-DEG1-PWY phenylalanine degradation/tyrosine biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 84105 PCBD2 HUMAN_SAM-PWY S-adenosyl-L-methionine biosynthesis 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 27430 MAT2B HUMAN_PWY-5453 methylglyoxal degradation III 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 231 AKR1B1 META_GLYCINE-SYN2-PWY glycine biosynthesis II 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 1738 DLD META_PWY66-422 D-galactose degradation V (Leloir pathway) 0.637496295262252 -0.450206813319771 3 1 0.00384615384615385 260 907 2582 GALE HUMAN_PWY3DJ-11281 sphingomyelin metabolism/ceramide salvage 0.642506275863027 -0.44237869438027 7 2 0.00769230769230769 260 907 55512,6609 SMPD3,SMPD1 META_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis 0.642506275863027 -0.44237869438027 7 2 0.00769230769230769 260 907 654364,4831 NME1-NME2,NME2 HUMAN_PWY-5067 glycogen biosynthesis 0.642506275863027 -0.44237869438027 7 2 0.00769230769230769 260 907 2997,7360 GYS1,UGP2 HUMAN_PWY-6313 serotonin degradation 0.642506275863027 -0.44237869438027 7 2 0.00769230769230769 260 907 4128,224 MAOA,ALDH3A2 HUMAN_PWY-6309 L-kynurenine degradation 0.653239394453306 -0.425811609763636 11 3 0.0115384615384615 260 907 56267,883,8942 CCBL2,CCBL1,KYNU HUMAN_LIPAS-PWY triacylglycerol degradation 0.653239394453306 -0.425811609763636 11 3 0.0115384615384615 260 907 9388,8228,26090 LIPG,PNPLA4,ABHD12 META_ANAEROFRUCAT-PWY homolactic fermentation 0.66455775929762 -0.408633483165174 15 4 0.0153846153846154 260 907 5224,5230,669,226 PGAM2,PGK1,BPGM,ALDOA META_PWY-6857 retinol biosynthesis 0.715551465649283 -0.334701752943816 12 3 0.0115384615384615 260 907 53630,9249,157506 BCO1,DHRS3,RDH10 HUMAN_PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II 0.718588894352511 -0.330465858983079 8 2 0.00769230769230769 260 907 6675,2582 UAP1,GALE HUMAN_2PHENDEG-PWY phenylethylamine degradation I 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_HYDROXYPRODEG-PWY 4-hydroxyproline degradation 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 8659 ALDH4A1 META_PWY66-21 ethanol degradation II 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-5177 glutaryl-CoA degradation 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 2639 GCDH HUMAN_PWY-6292 cysteine biosynthesis 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 27430 MAT2B META_PWY-5067 glycogen biosynthesis II (from UDP-D-Glucose) 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 2997 GYS1 META_HYDROXYPRODEG-PWY trans-4-hydroxy-L-proline degradation I 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 8659 ALDH4A1 META_PWY66-162 ethanol degradation IV 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 55191 NADSYN1 META_POLYAMINSYN3-PWY superpathway of polyamine biosynthesis II 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 6611 SMS META_PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain) 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 55191 NADSYN1 META_PWY66-161 oxidative ethanol degradation III 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY66-387 fatty acid alpha-oxidation 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-4984 urea cycle 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 1373 CPS1 HUMAN_PWY66-425 lysine degradation II (pipecolate pathway) 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 501 ALDH7A1 HUMAN_THIOREDOX-PWY thioredoxin pathway 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 7296 TXNRD1 HUMAN_PWY-6517 N-acetylglucosamine degradation II 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 55577 NAGK HUMAN_PWY-6261 thyroid hormone metabolism II (via conjugation and/or degradation) 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 1734 DIO2 META_PWY66-387 fatty acid alpha-oxidation II 0.741756210343787 -0.298734647289751 4 1 0.00384615384615385 260 907 224 ALDH3A2 META_PWY66-400 glycolysis VI (metazoan) 0.765411680064913 -0.267341446027386 17 4 0.0153846153846154 260 907 5224,5230,669,226 PGAM2,PGK1,BPGM,ALDOA HUMAN_PWY66-400 glycolysis 0.765411680064913 -0.267341446027386 17 4 0.0153846153846154 260 907 5224,5230,669,226 PGAM2,PGK1,BPGM,ALDOA META_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 0.76885439493158 -0.26285367079618 13 3 0.0115384615384615 260 907 5298,8394,55361 PI4KB,PIP5K1A,PI4K2A HUMAN_PWY66-391 fatty acid beta-oxidation (peroxisome) 0.76885439493158 -0.26285367079618 13 3 0.0115384615384615 260 907 3295,3033,51 HSD17B4,HADH,ACOX1 META_NADSYN-PWY NAD biosynthesis II (from tryptophan) 0.780586616841209 -0.247709569090244 9 2 0.00769230769230769 260 907 55191,8942 NADSYN1,KYNU HUMAN_PWY3DJ-11470 sphingosine and sphingosine-1-phosphate metabolism 0.780586616841209 -0.247709569090244 9 2 0.00769230769230769 260 907 427,56848 ASAH1,SPHK2 META_PWY-6353 purine nucleotides degradation II (aerobic) 0.780586616841209 -0.247709569090244 9 2 0.00769230769230769 260 907 3614,3615 IMPDH1,IMPDH2 HUMAN_FAO-PWY fatty acid beta-oxidation 0.81373964583458 -0.206114809553114 14 3 0.0115384615384615 260 907 3033,1632,3032 HADH,ECI1,HADHB HUMAN_PWY66-380 estradiol biosynthesis I 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 51170 HSD17B11 META_PWY-7199 pyrimidine deoxyribonucleosides salvage 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 7083 TK1 META_PWY-7433 mucin core 1 and core 2 O-glycosylation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 56913 C1GALT1 HUMAN_PWY-3661-1 glycine betaine degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 6470 SHMT1 META_PWY-6566 chondroitin biosynthesis 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 337876 CHSY3 HUMAN_PWY-6566 chondroitin and dermatan biosynthesis 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 337876 CHSY3 HUMAN_PWY-7180 2'-deoxy-alpha-D-ribose 1-phosphate degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 221 ALDH3B1 META_PWY-3661-1 glycine betaine degradation II (mammalian) 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 6470 SHMT1 META_TYRFUMCAT-PWY L-tyrosine degradation I 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 2954 GSTZ1 META_PWY66-367 ketogenesis 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 3157 HMGCS1 HUMAN_PWY4FS-6 phosphatidylethanolamine biosynthesis II 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 55500 ETNK1 HUMAN_TYRFUMCAT-PWY tyrosine degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 2954 GSTZ1 META_PWY-6398 melatonin degradation I 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 1545 CYP1B1 META_PWY-5651 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 8942 KYNU META_PWY-6402 superpathway of melatonin degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 1545 CYP1B1 HUMAN_PWY66-21 ethanol degradation II 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY66-162 ethanol degradation IV 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PLPSAL-PWY pyridoxal 5'-phosphate salvage 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 55163 PNPO HUMAN_PWY66-422 D-galactose degradation V (Leloir pathway) 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 2582 GALE HUMAN_UDPNACETYLGALSYN-PWY UDP-N-acetyl-D-glucosamine biosynthesis II 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 6675 UAP1 META_PWY-6261 thyroid hormone metabolism II (via conjugation and/or degradation) 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 1734 DIO2 HUMAN_PWY-7199 pyrimidine deoxyribonucleosides salvage 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 7083 TK1 HUMAN_PWY-5030 histidine degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 144193 AMDHD1 META_PWY-7209 superpathway of pyrimidine ribonucleosides degradation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 7378 UPP1 META_PWY-4081 glutathione redox reactions I 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 2879 GPX4 HUMAN_PWY-5966-1 fatty acid biosynthesis initiation 0.816112118775145 -0.203203532996873 5 1 0.00384615384615385 260 907 27349 MCAT HUMAN_PWY-6342 noradrenaline and adrenaline degradation 0.830295258480668 -0.185973908340276 10 2 0.00769230769230769 260 907 4128,224 MAOA,ALDH3A2 HUMAN_PWY-7049 icosapentaenoate biosynthesis II (metazoa) 0.830295258480668 -0.185973908340276 10 2 0.00769230769230769 260 907 9415,60481 FADS2,ELOVL5 HUMAN_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 0.835627058717684 -0.179572867442881 23 5 0.0192307692307692 260 907 138429,8396,8394,5298,55361 PIP5KL1,PIP4K2B,PIP5K1A,PI4KB,PI4K2A META_PWY66-373 sucrose degradation V (sucrose alpha-glucosidase) 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 226 ALDOA META_PWY-6342 noradrenaline and adrenaline degradation 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-6557 glycoaminoglycan-protein linkage region biosynthesis 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 26229 B3GAT3 HUMAN_PWY-5996 oleate biosynthesis 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 79966 SCD5 HUMAN_PWY66-161 oxidative ethanol degradation III 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 224 ALDH3A2 HUMAN_PWY-4081 glutathione redox reactions I 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 2879 GPX4 HUMAN_PWY-7209 pyrimidine ribonucleosides degradation 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 7378 UPP1 META_PWY-5327 superpathway of L-lysine degradation 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 501 ALDH7A1 META_PWY-6557 glycoaminoglycan-protein linkage region biosynthesis 0.869117494742074 -0.140276956018536 6 1 0.00384615384615385 260 907 26229 B3GAT3 HUMAN_PWY-6402 superpathway of melatonin degradation 0.869641006042701 -0.139674789223999 11 2 0.00769230769230769 260 907 4128,1545 MAOA,CYP1B1 HUMAN_NADSYN-PWY NAD de novo biosynthesis 0.869641006042701 -0.139674789223999 11 2 0.00769230769230769 260 907 55191,8942 NADSYN1,KYNU HUMAN_PWY-7433 mucin core 1 and core 2 O-glycosylation 0.887538413719329 -0.119303475505219 25 5 0.0192307692307692 260 907 56913,6483,63917,6484,55568 C1GALT1,ST3GAL2,GALNT11,ST3GAL4,GALNT10 META_PWY66-391 fatty acid beta-oxidation VI (peroxisome) 0.900458914123545 -0.104850741033275 12 2 0.00769230769230769 260 907 3295,51 HSD17B4,ACOX1 HUMAN_PWY-5651 tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 0.906886031225327 -0.097738491420062 7 1 0.00384615384615385 260 907 8942 KYNU HUMAN_PWY-5994 palmitate biosynthesis 0.906886031225327 -0.097738491420062 7 1 0.00384615384615385 260 907 54995 OXSM HUMAN_SALVADEHYPOX-PWY adenosine nucleotides degradation 0.906886031225327 -0.097738491420062 7 1 0.00384615384615385 260 907 57665 RDH14 META_PWY-6567 chondroitin sulfate biosynthesis (late stages) 0.906886031225327 -0.097738491420062 7 1 0.00384615384615385 260 907 50515 CHST11 HUMAN_PWY66-373 sucrose degradation 0.906886031225327 -0.097738491420062 7 1 0.00384615384615385 260 907 226 ALDOA HUMAN_PWY-6567 chondroitin sulfate biosynthesis (late stages) 0.92438700852386 -0.0786244546358185 13 2 0.00769230769230769 260 907 337876,50515 CHSY3,CHST11 META_PWY-6861 the visual cycle I (vertebrates) 0.92438700852386 -0.0786244546358185 13 2 0.00769230769230769 260 907 9249,157506 DHRS3,RDH10 META_PWY-6569 chondroitin sulfate biosynthesis 0.926663322716978 -0.0761649695508761 18 3 0.0115384615384615 260 907 337876,50515,26229 CHSY3,CHST11,B3GAT3 HUMAN_TRYPTOPHAN-DEGRADATION-1 tryptophan degradation 0.933785622209371 -0.0685083936409721 8 1 0.00384615384615385 260 907 8942 KYNU META_PWY-7426 mannosyl-glycoprotein N-acetylglucosaminyltransferases 0.933785622209371 -0.0685083936409721 8 1 0.00384615384615385 260 907 4124 MAN2A1 META_TRYPTOPHAN-DEGRADATION-1 L-tryptophan degradation III (eukaryotic) 0.933785622209371 -0.0685083936409721 8 1 0.00384615384615385 260 907 8942 KYNU HUMAN_PWY-5451 acetone degradation I (to methylglyoxal) 0.933785622209371 -0.0685083936409721 8 1 0.00384615384615385 260 907 231 AKR1B1 HUMAN_PWY-7434 terminal O-glycans residues modification 0.933785622209371 -0.0685083936409721 8 1 0.00384615384615385 260 907 8704 B4GALT2 HUMAN_PWY-6569 chondroitin sulfate biosynthesis 0.942723694239483 -0.0589820464528264 19 3 0.0115384615384615 260 907 337876,50515,26229 CHSY3,CHST11,B3GAT3 META_FAO-PWY fatty acid beta-oxidation I 0.942828235639329 -0.0588711596633438 14 2 0.00769230769230769 260 907 3033,3032 HADH,HADHB META_PWY-6367 D-myo-inositol-5-phosphate metabolism 0.952935497883604 -0.0482080608466654 9 1 0.00384615384615385 260 907 90809 TMEM55B HUMAN_PWY66-401 superpathway of tryptophan utilization 0.955500526351532 -0.0455199644369354 34 6 0.0230769230769231 260 907 4128,55191,224,8942,10327,1545 MAOA,NADSYN1,ALDH3A2,KYNU,AKR1A1,CYP1B1 HUMAN_PWY-6571 dermatan sulfate biosynthesis 0.956950253821547 -0.0440038702579554 15 2 0.00769230769230769 260 907 337876,26229 CHSY3,B3GAT3 HUMAN_PWY-6861 the visual cycle I (vertebrates) 0.956950253821547 -0.0440038702579554 15 2 0.00769230769230769 260 907 9249,157506 DHRS3,RDH10 META_PWY-6571 dermatan sulfate biosynthesis 0.956950253821547 -0.0440038702579554 15 2 0.00769230769230769 260 907 337876,26229 CHSY3,B3GAT3 HUMAN_DETOX1-PWY-1 reactive oxygen species degradation 0.966562191153541 -0.0340096356335689 10 1 0.00384615384615385 260 907 493869 GPX8 HUMAN_PWY-6398 melatonin degradation I 0.966562191153541 -0.0340096356335689 10 1 0.00384615384615385 260 907 1545 CYP1B1 META_PWY-6558 heparan sulfate biosynthesis (late stages) 0.975854262534557 -0.0244420248921708 17 2 0.00769230769230769 260 907 2135,26035 EXTL2,GLCE HUMAN_PWY-6857 retinol biosynthesis 0.975854262534557 -0.0244420248921708 17 2 0.00769230769230769 260 907 9249,157506 DHRS3,RDH10 META_PWY-6564 heparan sulfate biosynthesis 0.979607885754967 -0.0206029039620798 23 3 0.0115384615384615 260 907 2135,26035,26229 EXTL2,GLCE,B3GAT3 HUMAN_PWY-6000 gamma-linolenate biosynthesis 0.983144800171986 -0.0169988653373244 12 1 0.00384615384615385 260 907 9415 FADS2 HUMAN_PWY-6558 heparan sulfate biosynthesis (late stages) 0.990084868722736 -0.00996461354520232 20 2 0.00769230769230769 260 907 2135,26035 EXTL2,GLCE HUMAN_PWY-6564 heparan sulfate biosynthesis 0.99095404479997 -0.00908711828039604 26 3 0.0115384615384615 260 907 2135,26035,26229 EXTL2,GLCE,B3GAT3 HUMAN_PWY-7305 superpathway of steroid hormone biosynthesis 0.991519209517869 -0.00851695701140713 14 1 0.00384615384615385 260 907 51170 HSD17B11 HUMAN_LIPASYN-PWY phospholipases 0.996092383190897 -0.00391527149121647 29 3 0.0115384615384615 260 907 81579,50640,201164 PLA2G12A,PNPLA8,PLD6 HUMAN_PWY-6367 D-myo-inositol-5-phosphate metabolism 0.99698357548736 -0.00302098309043835 17 1 0.00384615384615385 260 907 90809 TMEM55B HUMAN_PWY0-1313 acetate conversion to acetyl-CoA 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6076 vitamin D3 biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6620 guanine and guanosine salvage 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY0-662 PRPP biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6076 vitamin D3 biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-7179-1 purine deoxyribonucleosides degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_GLYSYN-ALA-PWY glycine biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY66-397 resolvin D biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-5340 sulfate activation for sulfonation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY66-301 catecholamine biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6138 CMP-N-acetylneuraminate biosynthesis I (eukaryotes) 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-5874 heme degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY3O-4106 NAD salvage pathway III 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6620 guanine and guanosine salvage 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6370 ascorbate recycling (cytosolic) 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY66-397 resolvin D biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6241 thyroid hormone biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-5525 D-glucuronate degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-5340 sulfate activation for sulfonation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-5030 L-histidine degradation III 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_FASYN-ELONG-PWY fatty acid elongation -- saturated 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6138 CMP-N-acetylneuraminate biosynthesis I (eukaryotes) 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY66-380 estradiol biosynthesis I (via estrone) 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-5269 cardiolipin biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6181 histamine degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY0-662 PRPP biosynthesis I 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-5177 glutaryl-CoA degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_SERDEG-PWY L-serine degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_GLUDEG-I-PWY GABA shunt 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6145 superpathway of sialic acids and CMP-sialic acids biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-7179-1 purine deoxyribonucleosides degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-5505 L-glutamate and L-glutamine biosynthesis 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-1801 formaldehyde oxidation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-7306 estradiol biosynthesis II 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_UDPNACETYLGALSYN-PWY UDP-N-acetyl-D-glucosamine biosynthesis II 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6370 ascorbate recycling (cytosolic) 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 HUMAN_PWY-6608 guanosine nucleotides degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY-6181 histamine degradation 0.999999999992147 -7.85300990902016e-12 2 0 0 260 907 META_PWY66-382 mineralocorticoid biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-5996 oleate biosynthesis II (animals and fungi) 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-7193 pyrimidine ribonucleosides salvage I 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-6609 adenine and adenosine salvage III 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY66-381 glucocorticoid biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-4202 arsenate detoxification I (glutaredoxin) 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY66-392 lipoxin biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-6875 retinoate biosynthesis II 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY66-382 mineralocorticoid biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-6430 thymine degradation 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY66-381 glucocorticoid biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY66-301 catecholamine biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-6100 L-carnitine biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-6875 retinoate biosynthesis II 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-7185 UTP and CTP dephosphorylation I 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY0-1296 purine ribonucleosides degradation 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-3982 uracil degradation 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY0-1182 trehalose degradation 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-6100 L-carnitine biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_NAD-BIOSYNTHESIS-III NAD salvage 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-7193 pyrimidine ribonucleosides salvage I 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-7177 UTP and CTP dephosphorylation II 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY-6609 adenine and adenosine salvage III 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_GLUAMCAT-PWY N-acetylglucosamine degradation I 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-4202 arsenate detoxification I (glutaredoxin) 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-3982 uracil degradation I (reductive) 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_GLUDEG-I-PWY GABA shunt 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY0-1264 biotin-carboxyl carrier protein assembly 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY66-221 nicotine degradation V 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 HUMAN_PWY66-392 lipoxin biosynthesis 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-7185 UTP and CTP dephosphorylation I 0.999999999997544 -2.45625395023374e-12 3 0 0 260 907 META_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6292 superpathway of L-cysteine biosynthesis (mammalian) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6133 (S)-reticuline biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY66-421 homocarnosine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_P121-PWY adenine and adenosine salvage I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6273 phosphatidylethanolamine biosynthesis III 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5686 UMP biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_ALANINE-SYN2-PWY L-alanine biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_GLYCGREAT-PWY creatine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-7506 phosphatidylserine biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5966 fatty acid biosynthesis initiation II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-46 putrescine biosynthesis III 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-5652 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6132 lanosterol biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6377 alpha-tocopherol degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_GLYCGREAT-PWY creatine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_GLUT-REDOX-PWY glutathione redox reactions II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-5754 4-hydroxybenzoate biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_BGALACT-PWY lactose degradation III 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-40 putrescine biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7506 phosphatidylserine biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6938 NADH repair 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6502 oxidized GTP and dGTP detoxification 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7219 adenosine ribonucleotides de novo biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7299 progesterone biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_HOMOCYSDEGR-PWY cysteine biosynthesis/homocysteine degradation (trans-sulfuration) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5754 4-hydroxybenzoate biosynthesis I (eukaryotes) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY0-1305 glutamate dependent acid resistance 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_GLNSYN-PWY L-glutamine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_SERDEG-PWY L-serine degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7112 4-hydroxy-2-nonenal detoxification 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-40 putrescine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7306 estradiol biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-7299 progesterone biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6619 adenine and adenosine salvage VI 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY66-421 homocarnosine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5766 L-glutamate degradation X 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6173 histamine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY66-241 bupropion degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_GLUTAMATE-SYN2-PWY glutamate biosynthesis/degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY66-420 carnosine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_GLUTAMATE-SYN2-PWY L-glutamate biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_HISHP-PWY L-histidine degradation VI 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_ALANINE-DEG3-PWY L-alanine degradation III 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6938 NADH repair 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_NADPHOS-DEPHOS-PWY-1 NAD phosphorylation and dephosphorylation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_BSUBPOLYAMSYN-PWY spermidine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7501 phosphatidylserine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6132 lanosterol biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY66-426 hydrogen sulfide biosynthesis (trans-sulfuration) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY6666-1 anandamide degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY66-420 carnosine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-46 putrescine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5652 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6535 4-aminobutyrate degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-66 GDP-L-fucose biosynthesis I (from GDP-D-mannose) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6173 histamine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6481 L-dopachrome biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-7501 phosphatidylserine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_GLUT-REDOX-PWY glutathione redox reactions II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_MGLDLCTANA-PWY methylglyoxal degradation VI 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-5963 thio-molybdenum cofactor biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6502 oxidized GTP and dGTP detoxification 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5886 4-hydroxyphenylpyruvate biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY0-1313 acetate conversion to acetyl-CoA 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6377 alpha-tocopherol degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_ALANINE-DEG3-PWY alanine biosynthesis/degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6134 L-tyrosine biosynthesis IV 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_NADPHOS-DEPHOS-PWY-1 NAD phosphorylation and dephosphorylation II (mammalian) 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_GLNSYN-PWY glutamine biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-5269 cardiolipin biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6481 L-dopachrome biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-7435 mucin core 3 and core 4 O-glycosylation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6241 thyroid hormone biosynthesis 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6535 4-aminobutanoate degradation I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_MGLDLCTANA-PWY methylglyoxal degradation VI 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6619 adenine and adenosine salvage II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY-6334 L-dopa degradation 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 HUMAN_PWY66-11 BMP Signalling Pathway 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY-6133 (S)-reticuline biosynthesis II 1.00000000000013 1.31894495325469e-13 1 0 0 260 907 META_PWY66-368 ketolysis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-7434 terminal O-glycans residues modification 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-6158 creatine-phosphate biosynthesis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY66-368 ketolysis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-6568 dermatan sulfate biosynthesis (late stages) 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-7177 UTP and CTP dephosphorylation II 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-6158 creatine-phosphate biosynthesis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY66-367 ketogenesis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-4921 protein citrullination 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-6608 guanosine nucleotides degradation III 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-5661 GDP-glucose biosynthesis 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-6061 bile acid biosynthesis, neutral pathway 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-6568 dermatan sulfate biosynthesis (late stages) 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-5661-1 GDP-glucose biosynthesis II 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-7112 4-hydroxy-2-nonenal detoxification 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 META_PWY-5994 palmitate biosynthesis I (animals and fungi) 1.00000000000023 2.29662643069783e-13 4 0 0 260 907 HUMAN_PWY-4983 citrulline-nitric oxide cycle 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY-6030 serotonin and melatonin biosynthesis 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 HUMAN_PWY66-375 leukotriene biosynthesis 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY66-375 leukotriene biosynthesis 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 HUMAN_COA-PWY-1 coenzyme A biosynthesis 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY-6111 mitochondrial L-carnitine shuttle 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 HUMAN_PWY-6030 serotonin and melatonin biosynthesis 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_SALVADEHYPOX-PWY adenosine nucleotides degradation II 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY-4983 L-citrulline-nitric oxide cycle 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY66-201 nicotine degradation IV 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 HUMAN_PWY66-241 bupropion degradation 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_COA-PWY-1 coenzyme A biosynthesis II (mammalian) 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY-4921 protein citrullination 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 HUMAN_PWY-6111 mitochondrial L-carnitine shuttle 1.00000000000348 3.48343944835128e-12 5 0 0 260 907 META_PWY-5972 stearate biosynthesis I (animals and fungi) 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 META_PWY66-378 androgen biosynthesis 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 HUMAN_PWY-5143 fatty acid activation 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 HUMAN_PWY66-378 androgen biosynthesis 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 HUMAN_PWY-7455 allopregnanolone biosynthesis 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 META_PWY-7455 allopregnanolone biosynthesis 1.00000000000658 6.5804006124312e-12 6 0 0 260 907 META_PWY-6872 retinoate biosynthesis I 1.00000000000959 9.58824385448483e-12 7 0 0 260 907 HUMAN_PWY66-221 nicotine degradation III 1.00000000000959 9.58824385448483e-12 7 0 0 260 907 META_DETOX1-PWY-1 reactive oxygen species degradation 1.00000000000959 9.58824385448483e-12 7 0 0 260 907 HUMAN_PWY-6872 retinoate biosynthesis I 1.00000000001149 1.14912095951995e-11 8 0 0 260 907 HUMAN_PWY66-201 nicotine degradation IV 1.00000000001708 1.70811485806123e-11 10 0 0 260 907 META_PWY-7305 superpathway of steroid hormone biosynthesis 1.00000000001788 1.78759960233332e-11 11 0 0 260 907 HUMAN_PWY-5972 stearate biosynthesis 1.00000000001788 1.78759960233332e-11 11 0 0 260 907 HUMAN_PWY-6061 bile acid biosynthesis, neutral pathway 1.00000000002031 2.03090848000471e-11 12 0 0 260 907