TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
hsa03010	Ribosome	2.01345862754891e-24	-54.5621882782885	133	90	0.0504201680672269	1785	6908	6181,64960,6235,6156,6193,51263,9801,6135,6147,6217,6134,6194,6168,6227,6222,6207,6159,11224,7311,6133,6160,6182,79590,6169,6142,6232,4736,63931,6203,3921,55052,6167,54460,51069,6201,6233,6208,51264,9045,6173,65008,2197,6146,6188,51021,6231,6122,6202,6224,6209,51373,6138,6125,23521,64963,6137,51187,9349,6139,6170,6205,6155,63875,6143,29088,200916,6154,6166,6144,6171,6132,6128,6229,55173,54948,6189,51081,64979,51318,25873,6130,6210,6158,6161,9553,6223,6206,6152,11222,29074	RPLP2,MRPS15,RPS29,RPL30,RPS5,MRPL30,MRPL19,RPL11,RPL23A,RPS16,RPL10,RPS6,RPL37A,RPS21,RPS18,RPS13,RPL29,RPL35,UBA52,RPL9,RPL31,MRPL12,MRPL24,RPL38,RPL18A,RPS27,RPL10A,MRPS14,RPS9,RPSA,MRPL20,RPL37,MRPS21,MRPL2,RPS7,RPS27A,RPS14,MRPL27,RPL14,RPL36A,MRPL1,FAU,RPL22,RPS3,MRPS16,RPS26,RPL3,RPS8,RPS20,RPS15,MRPS17,RPL15,RPL5,RPL13A,MRPS11,RPL13,RSL24D1,RPL23,RPL17,RPL39,RPS11,RPL27,MRPL17,RPL19,MRPL15,RPL22L1,RPL26,RPL36AL,RPL21,RPL41,RPL8,RPL6,RPS24,MRPS10,MRPL16,RPS3A,MRPS7,MRPL36,MRPL35,RPL36,RPL7A,RPS15A,RPL28,RPL32,MRPL33,RPS19,RPS12,RPL24,MRPL3,MRPL18
ko03010	Ribosome	2.01345862754891e-24	-54.5621882782885	133	90	0.0504201680672269	1785	6908	6181,64960,6235,6156,6193,51263,9801,6135,6147,6217,6134,6194,6168,6227,6222,6207,6159,11224,7311,6133,6160,6169,79590,6182,6142,6232,4736,63931,6203,3921,55052,54460,6167,51069,6201,6233,6208,51264,9045,6173,65008,2197,6146,6188,51021,6231,6122,6202,6224,6209,51373,6138,6125,23521,64963,6137,51187,9349,6139,6205,6170,6155,63875,6143,29088,200916,6154,6166,6144,6132,6171,6128,55173,6229,54948,6189,51081,64979,51318,25873,6130,6161,6210,6158,9553,6223,6152,6206,11222,29074	RPLP2,MRPS15,RPS29,RPL30,RPS5,MRPL30,MRPL19,RPL11,RPL23A,RPS16,RPL10,RPS6,RPL37A,RPS21,RPS18,RPS13,RPL29,RPL35,UBA52,RPL9,RPL31,RPL38,MRPL24,MRPL12,RPL18A,RPS27,RPL10A,MRPS14,RPS9,RPSA,MRPL20,MRPS21,RPL37,MRPL2,RPS7,RPS27A,RPS14,MRPL27,RPL14,RPL36A,MRPL1,FAU,RPL22,RPS3,MRPS16,RPS26,RPL3,RPS8,RPS20,RPS15,MRPS17,RPL15,RPL5,RPL13A,MRPS11,RPL13,RSL24D1,RPL23,RPL17,RPS11,RPL39,RPL27,MRPL17,RPL19,MRPL15,RPL22L1,RPL26,RPL36AL,RPL21,RPL8,RPL41,RPL6,MRPS10,RPS24,MRPL16,RPS3A,MRPS7,MRPL36,MRPL35,RPL36,RPL7A,RPL32,RPS15A,RPL28,MRPL33,RPS19,RPL24,RPS12,MRPL3,MRPL18
ko03040	Spliceosome	4.05147060497234e-18	-40.0474517463449	132	81	0.0453781512605042	1785	6908	9984,10523,56949,9939,1659,6635,5093,153527,220988,83443,10992,55110,10286,9775,6429,6100,9716,3192,27339,10291,988,10772,11338,4809,6629,23020,3312,3183,51691,9129,10907,11017,1665,6426,9879,7307,10084,9128,6637,9785,10285,6627,3178,55119,10594,25949,84950,57461,6431,10946,25804,22985,151903,56259,23658,10189,55696,9343,24148,55660,29896,51639,6430,10915,199746,8175,6626,3304,9416,23450,22827,4686,27316,57187,10569,27258,3190,6428,10465,6633,51503	THOC1,CHERP,XAB2,RBM8A,DHX8,SNRPE,PCBP1,ZMAT2,HNRNPA3,SF3B5,SF3B2,MAGOHB,BCAS2,EIF4A3,SRSF4,RP9,AQR,HNRNPU,PRPF19,SF3A1,CDC5L,SRSF10,U2AF2,SNU13,SNRPB2,SNRNP200,HSPA8,HNRNPC,LSM8,PRPF3,TXNL4A,SNRNP27,DHX15,SRSF1,DDX46,U2AF1,PQBP1,PRPF4,SNRPG,DHX38,SMNDC1,SNRPA1,HNRNPA1,PRPF38B,PRPF8,SYF2,PRPF38A,ISY1,SRSF6,SF3A3,LSM4,ACIN1,CCDC12,CTNNBL1,LSM5,ALYREF,RBM22,EFTUD2,PRPF6,PRPF40A,TRA2A,SF3B6,SRSF5,TCERG1,U2AF1L4,SF3A2,SNRPA,HSPA1B,DDX23,SF3B3,PUF60,NCBP1,RBMX,THOC2,SLU7,LSM3,HNRNPK,SRSF3,PPIH,SNRPD2,CWC15
hsa03040	Spliceosome	4.05147060497234e-18	-40.0474517463449	132	81	0.0453781512605042	1785	6908	9984,10523,56949,9939,1659,6635,5093,153527,220988,83443,10992,55110,10286,9775,6429,6100,9716,3192,27339,10291,988,10772,11338,4809,6629,23020,3312,3183,51691,9129,10907,11017,1665,6426,9879,7307,10084,9128,6637,9785,10285,6627,3178,55119,10594,25949,84950,57461,6431,10946,25804,22985,151903,56259,23658,10189,55696,9343,24148,55660,29896,51639,6430,10915,199746,8175,6626,3304,9416,23450,22827,4686,27316,57187,10569,27258,3190,6428,10465,6633,51503	THOC1,CHERP,XAB2,RBM8A,DHX8,SNRPE,PCBP1,ZMAT2,HNRNPA3,SF3B5,SF3B2,MAGOHB,BCAS2,EIF4A3,SRSF4,RP9,AQR,HNRNPU,PRPF19,SF3A1,CDC5L,SRSF10,U2AF2,SNU13,SNRPB2,SNRNP200,HSPA8,HNRNPC,LSM8,PRPF3,TXNL4A,SNRNP27,DHX15,SRSF1,DDX46,U2AF1,PQBP1,PRPF4,SNRPG,DHX38,SMNDC1,SNRPA1,HNRNPA1,PRPF38B,PRPF8,SYF2,PRPF38A,ISY1,SRSF6,SF3A3,LSM4,ACIN1,CCDC12,CTNNBL1,LSM5,ALYREF,RBM22,EFTUD2,PRPF6,PRPF40A,TRA2A,SF3B6,SRSF5,TCERG1,U2AF1L4,SF3A2,SNRPA,HSPA1B,DDX23,SF3B3,PUF60,NCBP1,RBMX,THOC2,SLU7,LSM3,HNRNPK,SRSF3,PPIH,SNRPD2,CWC15
hsa04110	Cell cycle	1.72690828150665e-10	-22.4795182407521	124	65	0.0364145658263305	1785	6908	1875,9232,7157,4998,7531,4173,595,7465,5111,890,8555,51343,10393,8379,1027,51434,1032,1021,7709,902,1019,991,1871,10971,990,701,4171,8697,995,983,7532,8318,5933,4616,4085,8243,2932,11200,1870,3066,4172,1030,51433,4175,1111,4176,4174,4609,7272,545,23595,993,4999,10274,25847,6502,29882,5000,996,5001,7534,8556,7533,9133,1029	E2F5,PTTG1,TP53,ORC1,YWHAE,MCM4,CCND1,WEE1,PCNA,CCNA2,CDC14B,FZR1,ANAPC10,MAD1L1,CDKN1B,ANAPC7,CDKN2D,CDK6,ZBTB17,CCNH,CDK4,CDC20,E2F3,YWHAQ,CDC6,BUB1B,MCM2,CDC23,CDC25C,CDK1,YWHAG,CDC45,RBL1,GADD45B,MAD2L1,SMC1A,GSK3B,CHEK2,E2F2,HDAC2,MCM3,CDKN2B,ANAPC5,MCM6,CHEK1,MCM7,MCM5,MYC,TTK,ATR,ORC3,CDC25A,ORC2,STAG1,ANAPC13,SKP2,ANAPC2,ORC4,CDC27,ORC5,YWHAZ,CDC14A,YWHAH,CCNB2,CDKN2A
ko04110	Cell cycle	1.72690828150665e-10	-22.4795182407521	124	65	0.0364145658263305	1785	6908	1875,9232,7157,4998,7531,4173,595,7465,5111,890,8555,51343,10393,8379,1027,51434,1032,1021,7709,902,1019,991,1871,10971,990,701,4171,8697,995,983,7532,8318,5933,4616,4085,8243,2932,11200,1870,3066,4172,1030,51433,4175,1111,4176,4174,4609,7272,545,23595,993,4999,10274,25847,6502,29882,5000,996,5001,7534,8556,7533,9133,1029	E2F5,PTTG1,TP53,ORC1,YWHAE,MCM4,CCND1,WEE1,PCNA,CCNA2,CDC14B,FZR1,ANAPC10,MAD1L1,CDKN1B,ANAPC7,CDKN2D,CDK6,ZBTB17,CCNH,CDK4,CDC20,E2F3,YWHAQ,CDC6,BUB1B,MCM2,CDC23,CDC25C,CDK1,YWHAG,CDC45,RBL1,GADD45B,MAD2L1,SMC1A,GSK3B,CHEK2,E2F2,HDAC2,MCM3,CDKN2B,ANAPC5,MCM6,CHEK1,MCM7,MCM5,MYC,TTK,ATR,ORC3,CDC25A,ORC2,STAG1,ANAPC13,SKP2,ANAPC2,ORC4,CDC27,ORC5,YWHAZ,CDC14A,YWHAH,CCNB2,CDKN2A
hsa04141	Protein processing in endoplasmic reticulum	2.37292994785093e-10	-22.1617254734237	168	81	0.0453781512605042	1785	6908	80343,5589,9451,29978,821,10961,5886,56681,56605,5034,5887,51619,6185,23193,10802,10484,91319,468,3326,3312,3309,3301,10299,7415,1650,64215,3703,7466,6400,6747,22926,7323,6396,10808,7184,80331,1388,9871,23480,7186,3300,10905,7095,440275,3337,56886,6748,10483,55666,811,6184,1603,9632,5601,581,51465,10960,201595,3320,6048,10113,5609,80700,11253,80267,6746,10525,84447,9709,3304,51128,22872,79139,23640,23645,7494,7322,4217,10294,4780,1649	SEL1L2,PRKCSH,EIF2AK3,UBQLN2,CANX,ERP29,RAD23A,SAR1A,ERO1B,P4HB,RAD23B,UBE2D4,RPN2,GANAB,SEC24A,SEC23A,DERL3,ATF4,HSP90AB1,HSPA8,HSPA5,DNAJA1,MARCH6,VCP,DDOST,DNAJC1,STT3A,WFS1,SEL1L,SSR3,ATF6,UBE2D3,SEC13,HSPH1,HSP90B1,DNAJC5,ATF6B,SEC24D,SEC61G,TRAF2,DNAJB2,MAN1A2,SEC62,EIF2AK4,DNAJB1,UGGT1,SSR4,SEC23B,NPLOC4,CALR,RPN1,DAD1,SEC24C,MAPK9,BAX,UBE2J1,LMAN2,STT3B,HSP90AA1,RNF5,PREB,MAP2K7,UBXN6,MAN1B1,EDEM3,SSR2,HYOU1,SYVN1,HERPUD1,HSPA1B,SAR1B,SEC31A,DERL1,HSPBP1,PPP1R15A,XBP1,UBE2D2,MAP3K5,DNAJA2,NFE2L2,DDIT3
ko04141	Protein processing in endoplasmic reticulum	2.37292994785093e-10	-22.1617254734237	168	81	0.0453781512605042	1785	6908	80343,5589,9451,29978,821,10961,5886,56681,56605,5034,5887,51619,6185,23193,10802,10484,91319,468,3326,3312,3309,3301,10299,7415,1650,64215,3703,7466,6400,6747,22926,7323,6396,10808,7184,80331,1388,9871,23480,7186,3300,10905,7095,440275,3337,56886,6748,10483,55666,811,6184,1603,9632,5601,581,51465,10960,201595,3320,6048,10113,5609,80700,11253,80267,6746,10525,84447,9709,3304,51128,22872,79139,23640,23645,7494,7322,4217,10294,4780,1649	SEL1L2,PRKCSH,EIF2AK3,UBQLN2,CANX,ERP29,RAD23A,SAR1A,ERO1B,P4HB,RAD23B,UBE2D4,RPN2,GANAB,SEC24A,SEC23A,DERL3,ATF4,HSP90AB1,HSPA8,HSPA5,DNAJA1,MARCH6,VCP,DDOST,DNAJC1,STT3A,WFS1,SEL1L,SSR3,ATF6,UBE2D3,SEC13,HSPH1,HSP90B1,DNAJC5,ATF6B,SEC24D,SEC61G,TRAF2,DNAJB2,MAN1A2,SEC62,EIF2AK4,DNAJB1,UGGT1,SSR4,SEC23B,NPLOC4,CALR,RPN1,DAD1,SEC24C,MAPK9,BAX,UBE2J1,LMAN2,STT3B,HSP90AA1,RNF5,PREB,MAP2K7,UBXN6,MAN1B1,EDEM3,SSR2,HYOU1,SYVN1,HERPUD1,HSPA1B,SAR1B,SEC31A,DERL1,HSPBP1,PPP1R15A,XBP1,UBE2D2,MAP3K5,DNAJA2,NFE2L2,DDIT3
ko03013	RNA transport	2.3329119246281e-09	-19.8761485966008	166	78	0.0436974789915966	1785	6908	55706,8563,23511,9984,79228,8664,1964,9939,51367,7329,55110,54960,9775,55746,10248,8665,9972,1983,1977,11171,51095,29107,10921,60528,9631,5411,8021,8666,11260,8667,8661,1207,5903,7514,11102,1967,1979,10284,8662,8891,51068,8086,6396,8480,10250,53371,10482,8672,10775,22985,1915,129401,23165,7341,4927,8894,10189,79833,26019,10419,26986,3837,8893,1975,84305,1974,1973,9513,9669,1982,59343,100101267,4686,1968,57187,8892,23636,9818	NDC1,THOC5,NUP188,THOC1,THOC6,EIF3D,EIF1AX,RBM8A,POP5,UBE2I,MAGOHB,GEMIN8,EIF4A3,NUP133,POP7,EIF3F,NUP153,EIF5,EIF4E,STRAP,TRNT1,NXT1,RNPS1,ELAC2,NUP155,PNN,NUP214,EIF3G,XPOT,EIF3H,EIF3A,CLNS1A,RANBP2,XPO1,RPP14,EIF2B1,EIF4EBP2,SAP18,EIF3B,EIF2B3,NMD3,AAAS,SEC13,RAE1,SRRM1,NUP54,NXF1,EIF4G3,POP4,ACIN1,EEF1A1,NUP35,NUP205,SUMO1,NUP88,EIF2S2,ALYREF,GEMIN6,UPF2,PRMT5,PABPC1,KPNB1,EIF2B5,EIF4B,PYM1,EIF4A2,EIF4A1,FXR2,EIF5B,EIF4G2,SENP2,POM121C,NCBP1,EIF2S3,THOC2,EIF2B2,NUP62,NUP58
hsa03013	RNA transport	2.3329119246281e-09	-19.8761485966008	166	78	0.0436974789915966	1785	6908	55706,8563,23511,9984,79228,8664,1964,9939,51367,7329,55110,54960,9775,55746,10248,8665,9972,1983,1977,11171,51095,29107,10921,60528,9631,5411,8021,8666,11260,8667,8661,1207,5903,7514,11102,1967,1979,10284,8662,8891,51068,8086,6396,8480,10250,53371,10482,8672,10775,22985,1915,129401,23165,7341,4927,8894,10189,79833,26019,10419,26986,3837,8893,1975,84305,1974,1973,9513,9669,1982,59343,100101267,4686,1968,57187,8892,23636,9818	NDC1,THOC5,NUP188,THOC1,THOC6,EIF3D,EIF1AX,RBM8A,POP5,UBE2I,MAGOHB,GEMIN8,EIF4A3,NUP133,POP7,EIF3F,NUP153,EIF5,EIF4E,STRAP,TRNT1,NXT1,RNPS1,ELAC2,NUP155,PNN,NUP214,EIF3G,XPOT,EIF3H,EIF3A,CLNS1A,RANBP2,XPO1,RPP14,EIF2B1,EIF4EBP2,SAP18,EIF3B,EIF2B3,NMD3,AAAS,SEC13,RAE1,SRRM1,NUP54,NXF1,EIF4G3,POP4,ACIN1,EEF1A1,NUP35,NUP205,SUMO1,NUP88,EIF2S2,ALYREF,GEMIN6,UPF2,PRMT5,PABPC1,KPNB1,EIF2B5,EIF4B,PYM1,EIF4A2,EIF4A1,FXR2,EIF5B,EIF4G2,SENP2,POM121C,NCBP1,EIF2S3,THOC2,EIF2B2,NUP62,NUP58
hsa00190	Oxidative phosphorylation	2.14259113690681e-07	-15.3560797427271	120	57	0.0319327731092437	1785	6908	4698,4729,4712,7381,6391,523,521,506,51079,54539,1347,374291,4709,7386,4723,517,1337,10476,4708,7385,23545,4728,4731,1349,1537,51606,4700,529,4696,4705,55967,9114,4720,516,10632,1350,27089,1353,535,514,4701,9551,513,6392,51382,126328,9167,1351,4694,27068,9377,7388,498,4725,528,4713,1340	NDUFA5,NDUFV2,NDUFB6,UQCRB,SDHC,ATP6V1A,ATP5I,ATP5B,NDUFA13,NDUFB11,COX7A2,NDUFS7,NDUFB3,UQCRFS1,NDUFV1,ATP5G2,COX6A1,ATP5H,NDUFB2,UQCRC2,ATP6V0A2,NDUFS8,NDUFV3,COX7B,CYC1,ATP6V1H,NDUFA6,ATP6V1E1,NDUFA3,NDUFA10,NDUFA12,ATP6V0D1,NDUFS2,ATP5G1,ATP5L,COX7C,UQCRQ,COX11,ATP6V0A1,ATP5E,NDUFA7,ATP5J2,ATP5D,SDHD,ATP6V1D,NDUFA11,COX7A2L,COX8A,NDUFA1,PPA2,COX5A,UQCRH,ATP5A1,NDUFS5,ATP6V1C1,NDUFB7,COX6B1
ko00190	Oxidative phosphorylation	2.14259113690681e-07	-15.3560797427271	120	57	0.0319327731092437	1785	6908	4698,4729,4712,6391,523,7381,521,506,54539,51079,1347,374291,4709,7386,4723,517,1337,10476,4708,7385,23545,4728,4731,1349,1537,51606,4700,4696,55967,529,4705,9114,4720,516,10632,1350,27089,535,1353,4701,514,9551,6392,513,51382,126328,9167,1351,27068,4694,9377,7388,4725,498,528,4713,1340	NDUFA5,NDUFV2,NDUFB6,SDHC,ATP6V1A,UQCRB,ATP5I,ATP5B,NDUFB11,NDUFA13,COX7A2,NDUFS7,NDUFB3,UQCRFS1,NDUFV1,ATP5G2,COX6A1,ATP5H,NDUFB2,UQCRC2,ATP6V0A2,NDUFS8,NDUFV3,COX7B,CYC1,ATP6V1H,NDUFA6,NDUFA3,NDUFA12,ATP6V1E1,NDUFA10,ATP6V0D1,NDUFS2,ATP5G1,ATP5L,COX7C,UQCRQ,ATP6V0A1,COX11,NDUFA7,ATP5E,ATP5J2,SDHD,ATP5D,ATP6V1D,NDUFA11,COX7A2L,COX8A,PPA2,NDUFA1,COX5A,UQCRH,NDUFS5,ATP5A1,ATP6V1C1,NDUFB7,COX6B1
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3.41426595587874e-07	-14.890133128074	147	66	0.0369747899159664	1785	6908	4698,5564,4712,7381,5565,9451,51079,54539,4709,7386,998,3551,5296,7385,8503,4731,4700,4705,5970,4720,468,1350,2931,27089,208,5571,4701,6392,126328,4694,4296,9377,2932,7388,4713,1340,4729,6391,7186,5562,79602,54205,10062,374291,1347,3725,6945,4723,1337,4708,5601,581,4728,1537,1349,4696,55967,840,51422,3569,9167,7494,1351,4725,4217,1649	NDUFA5,PRKAB1,NDUFB6,UQCRB,PRKAB2,EIF2AK3,NDUFA13,NDUFB11,NDUFB3,UQCRFS1,CDC42,IKBKB,PIK3R2,UQCRC2,PIK3R3,NDUFV3,NDUFA6,NDUFA10,RELA,NDUFS2,ATF4,COX7C,GSK3A,UQCRQ,AKT2,PRKAG1,NDUFA7,SDHD,NDUFA11,NDUFA1,MAP3K11,COX5A,GSK3B,UQCRH,NDUFB7,COX6B1,NDUFV2,SDHC,TRAF2,PRKAA1,ADIPOR2,CYCS,NR1H3,NDUFS7,COX7A2,JUN,MLX,NDUFV1,COX6A1,NDUFB2,MAPK9,BAX,NDUFS8,CYC1,COX7B,NDUFA3,NDUFA12,CASP7,PRKAG2,IL6,COX7A2L,XBP1,COX8A,NDUFS5,MAP3K5,DDIT3
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	3.41426595587874e-07	-14.890133128074	147	66	0.0369747899159664	1785	6908	4698,5564,4712,7381,5565,9451,51079,54539,4709,7386,998,3551,5296,7385,8503,4731,4700,4705,5970,4720,468,1350,2931,27089,208,5571,4701,6392,126328,4694,4296,9377,2932,7388,4713,1340,4729,6391,7186,5562,79602,54205,10062,374291,1347,3725,6945,4723,1337,4708,5601,581,4728,1537,1349,4696,55967,840,51422,3569,9167,7494,1351,4725,4217,1649	NDUFA5,PRKAB1,NDUFB6,UQCRB,PRKAB2,EIF2AK3,NDUFA13,NDUFB11,NDUFB3,UQCRFS1,CDC42,IKBKB,PIK3R2,UQCRC2,PIK3R3,NDUFV3,NDUFA6,NDUFA10,RELA,NDUFS2,ATF4,COX7C,GSK3A,UQCRQ,AKT2,PRKAG1,NDUFA7,SDHD,NDUFA11,NDUFA1,MAP3K11,COX5A,GSK3B,UQCRH,NDUFB7,COX6B1,NDUFV2,SDHC,TRAF2,PRKAA1,ADIPOR2,CYCS,NR1H3,NDUFS7,COX7A2,JUN,MLX,NDUFV1,COX6A1,NDUFB2,MAPK9,BAX,NDUFS8,CYC1,COX7B,NDUFA3,NDUFA12,CASP7,PRKAG2,IL6,COX7A2L,XBP1,COX8A,NDUFS5,MAP3K5,DDIT3
ko05169	Epstein-Barr virus infection	1.15984607591389e-06	-13.6672232548282	199	82	0.0459383753501401	1785	6908	9451,7157,1147,1460,27044,7531,5566,51728,5606,5707,890,3551,5296,5971,1027,8503,55703,4791,1386,5970,26993,208,3312,10971,8021,7297,983,10014,7532,5432,8517,7514,5719,9759,5714,5709,5757,2932,5705,9861,10454,5700,3066,3122,5440,6908,3133,171568,7186,3134,5713,440275,4734,3105,3725,661,4609,5601,5717,3107,2960,6885,2959,6774,5431,10621,5609,7128,5702,6502,5710,5430,3587,11128,3304,51082,5608,9519,5434,7534,3516,7533	EIF2AK3,TP53,CHUK,CSNK2B,SND1,YWHAE,PRKACA,POLR3K,MAP2K3,PSMD1,CCNA2,IKBKB,PIK3R2,RELB,CDKN1B,PIK3R3,POLR3B,NFKB2,ATF2,RELA,AKAP8L,AKT2,HSPA8,YWHAQ,NUP214,TYK2,CDK1,HDAC5,YWHAG,POLR2C,IKBKG,XPO1,PSMD13,HDAC4,PSMD8,PSMD3,PTMA,GSK3B,PSMC5,PSMD6,TAB1,PSMC1,HDAC2,HLA-DRA,POLR2K,TBP,HLA-E,POLR3H,TRAF2,HLA-F,PSMD7,EIF2AK4,NEDD4,HLA-A,JUN,POLR3D,MYC,MAPK9,PSMD11,HLA-C,GTF2E1,MAP3K7,GTF2B,STAT3,POLR2B,POLR3F,MAP2K7,TNFAIP3,PSMC3,SKP2,PSMD4,POLR2A,IL10RA,POLR3A,HSPA1B,POLR1D,MAP2K6,TBPL1,POLR2E,YWHAZ,RBPJ,YWHAH
hsa05169	Epstein-Barr virus infection	1.15984607591389e-06	-13.6672232548282	199	82	0.0459383753501401	1785	6908	9451,7157,1147,1460,27044,7531,5566,51728,5606,5707,890,3551,5296,5971,1027,8503,55703,4791,1386,5970,26993,208,3312,10971,8021,7297,983,10014,7532,5432,8517,7514,5719,9759,5714,5709,5757,2932,5705,9861,10454,5700,3066,3122,5440,6908,3133,171568,7186,3134,5713,440275,4734,3105,3725,661,4609,5601,5717,3107,2960,6885,2959,6774,5431,10621,5609,7128,5702,6502,5710,5430,3587,11128,3304,51082,5608,9519,5434,7534,3516,7533	EIF2AK3,TP53,CHUK,CSNK2B,SND1,YWHAE,PRKACA,POLR3K,MAP2K3,PSMD1,CCNA2,IKBKB,PIK3R2,RELB,CDKN1B,PIK3R3,POLR3B,NFKB2,ATF2,RELA,AKAP8L,AKT2,HSPA8,YWHAQ,NUP214,TYK2,CDK1,HDAC5,YWHAG,POLR2C,IKBKG,XPO1,PSMD13,HDAC4,PSMD8,PSMD3,PTMA,GSK3B,PSMC5,PSMD6,TAB1,PSMC1,HDAC2,HLA-DRA,POLR2K,TBP,HLA-E,POLR3H,TRAF2,HLA-F,PSMD7,EIF2AK4,NEDD4,HLA-A,JUN,POLR3D,MYC,MAPK9,PSMD11,HLA-C,GTF2E1,MAP3K7,GTF2B,STAT3,POLR2B,POLR3F,MAP2K7,TNFAIP3,PSMC3,SKP2,PSMD4,POLR2A,IL10RA,POLR3A,HSPA1B,POLR1D,MAP2K6,TBPL1,POLR2E,YWHAZ,RBPJ,YWHAH
hsa03008	Ribosome biogenesis in eukaryotes	1.20849742973783e-06	-13.6261327636253	78	40	0.0224089635854342	1785	6908	84128,10813,55226,10482,1460,10775,29889,79631,51367,55651,51119,55813,10199,51096,4931,10248,22803,2091,23160,92856,4809,29107,26354,23560,65083,84135,166378,54433,55131,51602,55341,51077,7514,10607,54552,55127,23195,54464,51068,55505	WDR75,UTP14A,NAT10,NXF1,CSNK2B,POP4,GNL2,EFTUD1,POP5,NHP2,SBDS,UTP6,MPHOSPH10,UTP18,NVL,POP7,XRN2,FBL,WDR43,IMP4,SNU13,NXT1,GNL3,GTPBP4,NOL6,UTP15,SPATA5,GAR1,RBM28,NOP58,LSG1,FCF1,XPO1,TBL3,GNL3L,HEATR1,MDN1,XRN1,NMD3,NOP10
ko03008	Ribosome biogenesis in eukaryotes	1.20849742973783e-06	-13.6261327636253	78	40	0.0224089635854342	1785	6908	84128,10813,55226,10482,1460,10775,29889,79631,51367,55651,51119,55813,10199,51096,4931,10248,22803,2091,23160,92856,4809,29107,26354,23560,65083,84135,166378,54433,55131,51602,55341,51077,7514,10607,54552,55127,23195,54464,51068,55505	WDR75,UTP14A,NAT10,NXF1,CSNK2B,POP4,GNL2,EFTUD1,POP5,NHP2,SBDS,UTP6,MPHOSPH10,UTP18,NVL,POP7,XRN2,FBL,WDR43,IMP4,SNU13,NXT1,GNL3,GTPBP4,NOL6,UTP15,SPATA5,GAR1,RBM28,NOP58,LSG1,FCF1,XPO1,TBL3,GNL3L,HEATR1,MDN1,XRN1,NMD3,NOP10
hsa03030	DNA replication	1.64874385930896e-06	-13.3154968573743	36	23	0.0128851540616246	1785	6908	23649,5984,4175,5983,5422,3978,4171,10714,5424,4176,5982,246243,6118,4173,5111,4174,5981,6742,10535,57804,5425,2237,4172	POLA2,RFC4,MCM6,RFC3,POLA1,LIG1,MCM2,POLD3,POLD1,MCM7,RFC2,RNASEH1,RPA2,MCM4,PCNA,MCM5,RFC1,SSBP1,RNASEH2A,POLD4,POLD2,FEN1,MCM3
ko03030	DNA replication	1.64874385930896e-06	-13.3154968573743	36	23	0.0128851540616246	1785	6908	23649,5984,5983,4175,5422,3978,4171,10714,4176,5424,5982,246243,6118,4173,5111,4174,5981,10535,6742,57804,4172,5425,2237	POLA2,RFC4,RFC3,MCM6,POLA1,LIG1,MCM2,POLD3,MCM7,POLD1,RFC2,RNASEH1,RPA2,MCM4,PCNA,MCM5,RFC1,RNASEH2A,SSBP1,POLD4,MCM3,POLD2,FEN1
hsa05203	Viral carcinogenesis	2.33702549661046e-06	-12.9666315924925	205	83	0.0464985994397759	1785	6908	64764,5423,7157,6777,1960,27044,7531,10013,5566,440689,8365,595,890,998,2968,5366,8364,5296,8379,1027,8503,4791,1386,5970,3017,1021,468,1019,991,85236,10971,87,8340,2958,983,23352,10014,7532,572,1654,8517,8362,9759,5933,9093,6722,128312,5700,3066,1030,1388,8367,6908,5966,3133,7186,3134,1111,8347,8360,3105,3725,581,10379,2965,3107,2960,2959,6774,9114,148327,6502,3845,8363,8368,55697,9519,3190,7534,3516,7533,1642,1029	CREB3L2,POLB,TP53,STAT5B,EGR3,SND1,YWHAE,HDAC6,PRKACA,HIST2H2BF,HIST1H4H,CCND1,CCNA2,CDC42,GTF2H4,PMAIP1,HIST1H4C,PIK3R2,MAD1L1,CDKN1B,PIK3R3,NFKB2,ATF2,RELA,HIST1H2BD,CDK6,ATF4,CDK4,CDC20,HIST1H2BK,YWHAQ,ACTN1,HIST1H2BL,GTF2A2,CDK1,UBR4,HDAC5,YWHAG,BAD,DDX3X,IKBKG,HIST1H4K,HDAC4,RBL1,DNAJA3,SRF,HIST3H2BB,PSMC1,HDAC2,CDKN2B,ATF6B,HIST1H4E,TBP,REL,HLA-E,TRAF2,HLA-F,CHEK1,HIST1H2BC,HIST1H4D,HLA-A,JUN,BAX,IRF9,GTF2H1,HLA-C,GTF2E1,GTF2B,STAT3,ATP6V0D1,CREB3L4,SKP2,KRAS,HIST1H4J,HIST1H4L,VAC14,TBPL1,HNRNPK,YWHAZ,RBPJ,YWHAH,DDB1,CDKN2A
ko05203	Viral carcinogenesis	2.33702549661046e-06	-12.9666315924925	205	83	0.0464985994397759	1785	6908	64764,5423,7157,6777,1960,27044,7531,10013,5566,440689,8365,595,890,998,2968,5366,8364,5296,8379,1027,8503,4791,1386,5970,3017,1021,468,1019,991,85236,10971,87,8340,2958,983,23352,10014,7532,572,1654,8517,8362,9759,5933,9093,6722,128312,5700,3066,1030,1388,8367,6908,5966,3133,7186,3134,1111,8347,8360,3105,3725,581,10379,2965,3107,2960,2959,6774,9114,148327,6502,3845,8363,8368,55697,9519,3190,7534,3516,7533,1642,1029	CREB3L2,POLB,TP53,STAT5B,EGR3,SND1,YWHAE,HDAC6,PRKACA,HIST2H2BF,HIST1H4H,CCND1,CCNA2,CDC42,GTF2H4,PMAIP1,HIST1H4C,PIK3R2,MAD1L1,CDKN1B,PIK3R3,NFKB2,ATF2,RELA,HIST1H2BD,CDK6,ATF4,CDK4,CDC20,HIST1H2BK,YWHAQ,ACTN1,HIST1H2BL,GTF2A2,CDK1,UBR4,HDAC5,YWHAG,BAD,DDX3X,IKBKG,HIST1H4K,HDAC4,RBL1,DNAJA3,SRF,HIST3H2BB,PSMC1,HDAC2,CDKN2B,ATF6B,HIST1H4E,TBP,REL,HLA-E,TRAF2,HLA-F,CHEK1,HIST1H2BC,HIST1H4D,HLA-A,JUN,BAX,IRF9,GTF2H1,HLA-C,GTF2E1,GTF2B,STAT3,ATP6V0D1,CREB3L4,SKP2,KRAS,HIST1H4J,HIST1H4L,VAC14,TBPL1,HNRNPK,YWHAZ,RBPJ,YWHAH,DDB1,CDKN2A
ko05016	Huntington's disease	5.26919118319582e-06	-12.153633682864	187	76	0.0425770308123249	1785	6908	64764,4698,4712,7381,7157,25942,51079,54539,4709,7386,1768,517,7385,163,4731,4700,4705,4720,1639,1350,27089,842,1742,514,4701,7416,513,6392,5432,126328,1213,4694,9377,7388,10891,4713,1175,3066,1340,4729,5440,6908,6391,10540,54205,506,374291,1347,4723,1337,10476,51164,4708,581,4728,1537,1349,55967,4696,5431,6667,516,627,148327,23186,9001,6875,5430,127602,160,9167,1351,9519,5434,4725,498	CREB3L2,NDUFA5,NDUFB6,UQCRB,TP53,SIN3A,NDUFA13,NDUFB11,NDUFB3,UQCRFS1,DNAH6,ATP5G2,UQCRC2,AP2B1,NDUFV3,NDUFA6,NDUFA10,NDUFS2,DCTN1,COX7C,UQCRQ,CASP9,DLG4,ATP5E,NDUFA7,VDAC1,ATP5D,SDHD,POLR2C,NDUFA11,CLTC,NDUFA1,COX5A,UQCRH,PPARGC1A,NDUFB7,AP2S1,HDAC2,COX6B1,NDUFV2,POLR2K,TBP,SDHC,DCTN2,CYCS,ATP5B,NDUFS7,COX7A2,NDUFV1,COX6A1,ATP5H,DCTN4,NDUFB2,BAX,NDUFS8,CYC1,COX7B,NDUFA12,NDUFA3,POLR2B,SP1,ATP5G1,BDNF,CREB3L4,RCOR1,HAP1,TAF4B,POLR2A,DNAH14,AP2A1,COX7A2L,COX8A,TBPL1,POLR2E,NDUFS5,ATP5A1
hsa05016	Huntington's disease	5.26919118319582e-06	-12.153633682864	187	76	0.0425770308123249	1785	6908	64764,4698,4712,7381,7157,25942,51079,54539,4709,7386,1768,517,7385,163,4731,4700,4705,4720,1639,1350,27089,842,1742,514,4701,7416,513,6392,5432,126328,1213,4694,9377,7388,10891,4713,1175,3066,1340,4729,5440,6908,6391,10540,54205,506,374291,1347,4723,1337,10476,51164,4708,581,4728,1537,1349,55967,4696,5431,6667,516,627,148327,23186,9001,6875,5430,127602,160,9167,1351,9519,5434,4725,498	CREB3L2,NDUFA5,NDUFB6,UQCRB,TP53,SIN3A,NDUFA13,NDUFB11,NDUFB3,UQCRFS1,DNAH6,ATP5G2,UQCRC2,AP2B1,NDUFV3,NDUFA6,NDUFA10,NDUFS2,DCTN1,COX7C,UQCRQ,CASP9,DLG4,ATP5E,NDUFA7,VDAC1,ATP5D,SDHD,POLR2C,NDUFA11,CLTC,NDUFA1,COX5A,UQCRH,PPARGC1A,NDUFB7,AP2S1,HDAC2,COX6B1,NDUFV2,POLR2K,TBP,SDHC,DCTN2,CYCS,ATP5B,NDUFS7,COX7A2,NDUFV1,COX6A1,ATP5H,DCTN4,NDUFB2,BAX,NDUFS8,CYC1,COX7B,NDUFA12,NDUFA3,POLR2B,SP1,ATP5G1,BDNF,CREB3L4,RCOR1,HAP1,TAF4B,POLR2A,DNAH14,AP2A1,COX7A2L,COX8A,TBPL1,POLR2E,NDUFS5,ATP5A1
hsa03022	Basal transcription factors	5.31199622936608e-06	-12.1455428556236	45	26	0.0145658263305322	1785	6908	129685,6884,6881,6877,902,6872,2071,6908,6875,2958,2962,6873,8148,2968,83860,2963,9519,2965,6879,6883,2960,6882,2068,2959,2969,6878	TAF8,TAF13,TAF10,TAF5,CCNH,TAF1,ERCC3,TBP,TAF4B,GTF2A2,GTF2F1,TAF2,TAF15,GTF2H4,TAF3,GTF2F2,TBPL1,GTF2H1,TAF7,TAF12,GTF2E1,TAF11,ERCC2,GTF2B,GTF2I,TAF6
ko03022	Basal transcription factors	5.31199622936608e-06	-12.1455428556236	45	26	0.0145658263305322	1785	6908	129685,6881,6884,6877,902,6908,6872,2071,2958,6875,2962,8148,6873,83860,2968,2963,9519,2965,6879,6883,2068,2960,6882,2959,2969,6878	TAF8,TAF10,TAF13,TAF5,CCNH,TBP,TAF1,ERCC3,GTF2A2,TAF4B,GTF2F1,TAF15,TAF2,TAF3,GTF2H4,GTF2F2,TBPL1,GTF2H1,TAF7,TAF12,ERCC2,GTF2E1,TAF11,GTF2B,GTF2I,TAF6
ko03018	RNA degradation	7.31361022512399e-06	-11.8257735312727	77	38	0.0212885154061625	1785	6908	23019,9337,196513,25804,29883,9924,4849,80153,23016,23658,10766,11340,55802,22803,54512,27257,84186,26986,23404,10438,118460,80349,23517,23644,51691,5393,219988,167227,4848,9125,694,131870,3313,25904,27258,54464,170506,87178	CNOT1,CNOT8,DCP1B,LSM4,CNOT7,PAN2,CNOT3,EDC3,EXOSC7,LSM5,TOB2,EXOSC8,DCP1A,XRN2,EXOSC4,LSM1,ZCCHC7,PABPC1,EXOSC2,C1D,EXOSC6,WDR61,SKIV2L2,EDC4,LSM8,EXOSC9,PATL1,DCP2,CNOT2,RQCD1,BTG1,NUDT16,HSPA9,CNOT10,LSM3,XRN1,DHX36,PNPT1
hsa03018	RNA degradation	7.31361022512399e-06	-11.8257735312727	77	38	0.0212885154061625	1785	6908	23019,9337,196513,25804,29883,9924,4849,80153,23016,23658,10766,11340,55802,22803,54512,27257,84186,26986,23404,10438,118460,80349,23517,23644,51691,5393,219988,167227,4848,9125,694,131870,3313,25904,27258,54464,170506,87178	CNOT1,CNOT8,DCP1B,LSM4,CNOT7,PAN2,CNOT3,EDC3,EXOSC7,LSM5,TOB2,EXOSC8,DCP1A,XRN2,EXOSC4,LSM1,ZCCHC7,PABPC1,EXOSC2,C1D,EXOSC6,WDR61,SKIV2L2,EDC4,LSM8,EXOSC9,PATL1,DCP2,CNOT2,RQCD1,BTG1,NUDT16,HSPA9,CNOT10,LSM3,XRN1,DHX36,PNPT1
hsa03050	Proteasome	1.2109762850581e-05	-11.3214985835323	44	25	0.0140056022408964	1785	6908	5689,5693,5692,5702,5695,5713,5682,51371,5710,9491,5691,5687,5707,5696,5719,5709,5714,5690,5717,9861,10197,5705,5700,5686,5694	PSMB1,PSMB5,PSMB4,PSMC3,PSMB7,PSMD7,PSMA1,POMP,PSMD4,PSMF1,PSMB3,PSMA6,PSMD1,PSMB8,PSMD13,PSMD3,PSMD8,PSMB2,PSMD11,PSMD6,PSME3,PSMC5,PSMC1,PSMA5,PSMB6
ko03050	Proteasome	1.2109762850581e-05	-11.3214985835323	44	25	0.0140056022408964	1785	6908	5689,5693,5692,5702,5695,5713,5682,51371,5710,9491,5691,5707,5696,5687,5719,5709,5714,5690,5717,10197,9861,5705,5700,5686,5694	PSMB1,PSMB5,PSMB4,PSMC3,PSMB7,PSMD7,PSMA1,POMP,PSMD4,PSMF1,PSMB3,PSMD1,PSMB8,PSMA6,PSMD13,PSMD3,PSMD8,PSMB2,PSMD11,PSME3,PSMD6,PSMC5,PSMC1,PSMA5,PSMB6
ko03430	Mismatch repair	1.33865547511744e-05	-11.2212597315049	23	16	0.00896358543417367	1785	6908	5984,5983,3978,4292,10714,5982,5424,9156,6118,5111,4436,6742,5981,57804,5425,2956	RFC4,RFC3,LIG1,MLH1,POLD3,RFC2,POLD1,EXO1,RPA2,PCNA,MSH2,SSBP1,RFC1,POLD4,POLD2,MSH6
hsa03430	Mismatch repair	1.33865547511744e-05	-11.2212597315049	23	16	0.00896358543417367	1785	6908	5984,5983,3978,4292,10714,5424,5982,6118,9156,5111,4436,6742,5981,57804,2956,5425	RFC4,RFC3,LIG1,MLH1,POLD3,POLD1,RFC2,RPA2,EXO1,PCNA,MSH2,SSBP1,RFC1,POLD4,MSH6,POLD2
hsa05012	Parkinson's disease	2.10164445013475e-05	-10.7702053551886	129	55	0.030812324929972	1785	6908	4698,4729,7317,4712,7381,6391,54205,506,51079,54539,5566,11315,1347,374291,4709,7386,4723,517,1337,10476,4708,51465,7385,4728,4731,1349,1537,4700,7314,4696,4705,55967,2771,4720,516,1350,27089,842,514,4701,7416,2773,513,6622,6392,126328,9167,1351,4694,9377,7388,498,4725,4713,1340	NDUFA5,NDUFV2,UBA1,NDUFB6,UQCRB,SDHC,CYCS,ATP5B,NDUFA13,NDUFB11,PRKACA,PARK7,COX7A2,NDUFS7,NDUFB3,UQCRFS1,NDUFV1,ATP5G2,COX6A1,ATP5H,NDUFB2,UBE2J1,UQCRC2,NDUFS8,NDUFV3,COX7B,CYC1,NDUFA6,UBB,NDUFA3,NDUFA10,NDUFA12,GNAI2,NDUFS2,ATP5G1,COX7C,UQCRQ,CASP9,ATP5E,NDUFA7,VDAC1,GNAI3,ATP5D,SNCA,SDHD,NDUFA11,COX7A2L,COX8A,NDUFA1,COX5A,UQCRH,ATP5A1,NDUFS5,NDUFB7,COX6B1
hsa03420	Nucleotide excision repair	0.000179780333251421	-8.62377482315837	47	24	0.0134453781512605	1785	6908	5984,1643,2067,5983,902,2071,3978,10714,5424,5982,5886,6118,1069,5111,2968,2074,5887,2965,2073,5981,2068,57804,5425,1642	RFC4,DDB2,ERCC1,RFC3,CCNH,ERCC3,LIG1,POLD3,POLD1,RFC2,RAD23A,RPA2,CETN2,PCNA,GTF2H4,ERCC6,RAD23B,GTF2H1,ERCC5,RFC1,ERCC2,POLD4,POLD2,DDB1
ko03420	Nucleotide excision repair	0.000179780333251421	-8.62377482315837	47	24	0.0134453781512605	1785	6908	5984,1643,2067,5983,902,2071,3978,10714,5424,5982,5886,6118,1069,5111,2074,2968,5887,2965,2073,2068,5981,57804,1642,5425	RFC4,DDB2,ERCC1,RFC3,CCNH,ERCC3,LIG1,POLD3,POLD1,RFC2,RAD23A,RPA2,CETN2,PCNA,ERCC6,GTF2H4,RAD23B,GTF2H1,ERCC5,ERCC2,RFC1,POLD4,DDB1,POLD2
ko03015	mRNA surveillance pathway	0.000284408595459536	-8.1650986373571	91	39	0.0218487394957983	1785	6908	10250,9939,10978,10482,23283,5526,22985,55110,10189,5518,9775,100529063,53918,26019,2107,5521,51692,11052,26986,1477,29107,8731,84305,10921,80335,51585,5411,5529,4686,11051,29101,5527,5500,1478,2935,10284,55339,5528,10767	SRRM1,RBM8A,CLP1,NXF1,CSTF2T,PPP2R5B,ACIN1,MAGOHB,ALYREF,PPP2R1A,EIF4A3,BCL2L2-PABPN1,PELO,UPF2,ETF1,PPP2R2B,CPSF3,CPSF6,PABPC1,CSTF1,NXT1,RNMT,PYM1,RNPS1,WDR82,PCF11,PNN,PPP2R5E,NCBP1,NUDT21,SSU72,PPP2R5C,PPP1CB,CSTF2,GSPT1,SAP18,WDR33,PPP2R5D,HBS1L
hsa03015	mRNA surveillance pathway	0.000284408595459536	-8.1650986373571	91	39	0.0218487394957983	1785	6908	10250,9939,10978,10482,23283,5526,22985,55110,10189,5518,9775,100529063,53918,26019,2107,5521,51692,11052,26986,1477,29107,8731,84305,10921,80335,51585,5411,5529,4686,11051,29101,5527,5500,1478,2935,10284,55339,5528,10767	SRRM1,RBM8A,CLP1,NXF1,CSTF2T,PPP2R5B,ACIN1,MAGOHB,ALYREF,PPP2R1A,EIF4A3,BCL2L2-PABPN1,PELO,UPF2,ETF1,PPP2R2B,CPSF3,CPSF6,PABPC1,CSTF1,NXT1,RNMT,PYM1,RNPS1,WDR82,PCF11,PNN,PPP2R5E,NCBP1,NUDT21,SSU72,PPP2R5C,PPP1CB,CSTF2,GSPT1,SAP18,WDR33,PPP2R5D,HBS1L
ko04120	Ubiquitin mediated proteolysis	0.000302183023362059	-8.10447768653333	137	54	0.0302521008403361	1785	6908	7323,23291,51433,9820,9320,7317,57448,9886,55284,26272,55585,23327,9354,7329,329,51366,4734,8651,51343,51465,10393,51619,23295,51434,89910,54926,27339,26259,140739,1643,330,25847,9616,991,6502,7319,868,7328,6921,29882,84447,8697,4591,55236,996,8453,7322,23221,7320,27338,11065,7334,8945,1642	UBE2D3,FBXW11,ANAPC5,CUL7,TRIP12,UBA1,BIRC6,RHOBTB1,UBE2W,FBXO4,UBE2Q1,NEDD4L,UBE4A,UBE2I,BIRC2,UBR5,NEDD4,SOCS1,FZR1,UBE2J1,ANAPC10,UBE2D4,MGRN1,ANAPC7,UBE3B,UBE2R2,PRPF19,FBXW8,UBE2F,DDB2,BIRC3,ANAPC13,RNF7,CDC20,SKP2,UBE2A,CBLB,UBE2H,TCEB1,ANAPC2,SYVN1,CDC23,TRIM37,UBA6,CDC27,CUL2,UBE2D2,RHOBTB2,UBE2B,UBE2S,UBE2C,UBE2N,BTRC,DDB1
hsa04120	Ubiquitin mediated proteolysis	0.000302183023362059	-8.10447768653333	137	54	0.0302521008403361	1785	6908	7323,23291,51433,9820,9320,7317,57448,9886,55284,26272,55585,23327,9354,7329,329,51366,4734,8651,51343,51465,10393,51619,23295,51434,89910,54926,27339,26259,140739,1643,330,25847,9616,991,6502,7319,868,7328,6921,29882,84447,8697,4591,55236,996,8453,7322,23221,7320,27338,11065,7334,8945,1642	UBE2D3,FBXW11,ANAPC5,CUL7,TRIP12,UBA1,BIRC6,RHOBTB1,UBE2W,FBXO4,UBE2Q1,NEDD4L,UBE4A,UBE2I,BIRC2,UBR5,NEDD4,SOCS1,FZR1,UBE2J1,ANAPC10,UBE2D4,MGRN1,ANAPC7,UBE3B,UBE2R2,PRPF19,FBXW8,UBE2F,DDB2,BIRC3,ANAPC13,RNF7,CDC20,SKP2,UBE2A,CBLB,UBE2H,TCEB1,ANAPC2,SYVN1,CDC23,TRIM37,UBA6,CDC27,CUL2,UBE2D2,RHOBTB2,UBE2B,UBE2S,UBE2C,UBE2N,BTRC,DDB1
hsa05010	Alzheimer's disease	0.000539472262370776	-7.52491918817303	162	61	0.0341736694677871	1785	6908	4698,4729,4712,7381,6391,9451,54205,506,51079,54539,5663,1347,374291,4709,7386,805,4723,488,517,1337,10476,4708,7385,4728,4731,1349,1537,4700,4696,4705,55967,4720,516,6868,2597,1350,51107,27089,842,514,4701,8772,513,6622,6392,572,840,3416,126328,9167,1351,4694,9377,2932,7388,22926,498,4725,4713,23385,1340	NDUFA5,NDUFV2,NDUFB6,UQCRB,SDHC,EIF2AK3,CYCS,ATP5B,NDUFA13,NDUFB11,PSEN1,COX7A2,NDUFS7,NDUFB3,UQCRFS1,CALM2,NDUFV1,ATP2A2,ATP5G2,COX6A1,ATP5H,NDUFB2,UQCRC2,NDUFS8,NDUFV3,COX7B,CYC1,NDUFA6,NDUFA3,NDUFA10,NDUFA12,NDUFS2,ATP5G1,ADAM17,GAPDH,COX7C,APH1A,UQCRQ,CASP9,ATP5E,NDUFA7,FADD,ATP5D,SNCA,SDHD,BAD,CASP7,IDE,NDUFA11,COX7A2L,COX8A,NDUFA1,COX5A,GSK3B,UQCRH,ATF6,ATP5A1,NDUFS5,NDUFB7,NCSTN,COX6B1
ko05010	Alzheimer's disease	0.000539472262370776	-7.52491918817303	162	61	0.0341736694677871	1785	6908	4698,4729,4712,7381,6391,9451,54205,506,51079,54539,5663,1347,374291,4709,7386,805,4723,488,517,1337,10476,4708,7385,4728,4731,1349,1537,4700,4696,4705,55967,4720,516,6868,2597,1350,51107,27089,842,514,4701,8772,513,6622,6392,572,840,3416,126328,9167,1351,4694,9377,2932,7388,22926,498,4725,4713,23385,1340	NDUFA5,NDUFV2,NDUFB6,UQCRB,SDHC,EIF2AK3,CYCS,ATP5B,NDUFA13,NDUFB11,PSEN1,COX7A2,NDUFS7,NDUFB3,UQCRFS1,CALM2,NDUFV1,ATP2A2,ATP5G2,COX6A1,ATP5H,NDUFB2,UQCRC2,NDUFS8,NDUFV3,COX7B,CYC1,NDUFA6,NDUFA3,NDUFA10,NDUFA12,NDUFS2,ATP5G1,ADAM17,GAPDH,COX7C,APH1A,UQCRQ,CASP9,ATP5E,NDUFA7,FADD,ATP5D,SNCA,SDHD,BAD,CASP7,IDE,NDUFA11,COX7A2L,COX8A,NDUFA1,COX5A,GSK3B,UQCRH,ATF6,ATP5A1,NDUFS5,NDUFB7,NCSTN,COX6B1
hsa03440	Homologous recombination	0.000720008009685667	-7.23624822145262	29	16	0.00896358543417367	1785	6908	8940,7156,5893,8438,641,10714,5424,25788,6118,5889,675,7516,7517,6742,57804,5425	TOP3B,TOP3A,RAD52,RAD54L,BLM,POLD3,POLD1,RAD54B,RPA2,RAD51C,BRCA2,XRCC2,XRCC3,SSBP1,POLD4,POLD2
ko03440	Homologous recombination	0.000720008009685667	-7.23624822145262	29	16	0.00896358543417367	1785	6908	8940,7156,5893,8438,641,10714,5424,25788,6118,5889,675,7516,7517,6742,57804,5425	TOP3B,TOP3A,RAD52,RAD54L,BLM,POLD3,POLD1,RAD54B,RPA2,RAD51C,BRCA2,XRCC2,XRCC3,SSBP1,POLD4,POLD2
hsa05221	Acute myeloid leukemia	0.00093790861007813	-6.97185804432505	57	26	0.0145658263305322	1785	6908	5914,673,3728,2475,5894,208,5604,3845,6777,1147,6934,572,595,5467,8517,369,4609,3551,5296,8503,6198,11040,5292,6774,5970,6199	RARA,BRAF,JUP,MTOR,RAF1,AKT2,MAP2K1,KRAS,STAT5B,CHUK,TCF7L2,BAD,CCND1,PPARD,IKBKG,ARAF,MYC,IKBKB,PIK3R2,PIK3R3,RPS6KB1,PIM2,PIM1,STAT3,RELA,RPS6KB2
ko05221	Acute myeloid leukemia	0.00093790861007813	-6.97185804432505	57	26	0.0145658263305322	1785	6908	5914,673,3728,2475,5894,208,5604,3845,6777,1147,6934,572,595,5467,8517,369,4609,3551,5296,8503,6198,11040,5292,6774,5970,6199	RARA,BRAF,JUP,MTOR,RAF1,AKT2,MAP2K1,KRAS,STAT5B,CHUK,TCF7L2,BAD,CCND1,PPARD,IKBKG,ARAF,MYC,IKBKB,PIK3R2,PIK3R3,RPS6KB1,PIM2,PIM1,STAT3,RELA,RPS6KB2
ko05212	Pancreatic cancer	0.00102715801494648	-6.88095949916368	66	29	0.0162464985994398	1785	6908	673,1019,5894,10928,208,842,5604,7157,1871,5900,3845,1147,598,572,595,8517,675,369,998,3551,5296,5601,6772,8503,6774,1870,5970,1021,1029	BRAF,CDK4,RAF1,RALBP1,AKT2,CASP9,MAP2K1,TP53,E2F3,RALGDS,KRAS,CHUK,BCL2L1,BAD,CCND1,IKBKG,BRCA2,ARAF,CDC42,IKBKB,PIK3R2,MAPK9,STAT1,PIK3R3,STAT3,E2F2,RELA,CDK6,CDKN2A
hsa05212	Pancreatic cancer	0.00102715801494648	-6.88095949916368	66	29	0.0162464985994398	1785	6908	673,1019,5894,10928,208,842,5604,7157,1871,5900,3845,1147,598,572,595,8517,675,369,998,3551,5296,5601,6772,8503,6774,1870,5970,1021,1029	BRAF,CDK4,RAF1,RALBP1,AKT2,CASP9,MAP2K1,TP53,E2F3,RALGDS,KRAS,CHUK,BCL2L1,BAD,CCND1,IKBKG,BRCA2,ARAF,CDC42,IKBKB,PIK3R2,MAPK9,STAT1,PIK3R3,STAT3,E2F2,RELA,CDK6,CDKN2A
ko00020	Citrate cycle (TCA cycle)	0.00117604274517244	-6.74560008223052	30	16	0.00896358543417367	1785	6908	5160,50,5091,8802,6391,4191,47,55753,5105,2271,1431,4967,3420,1738,1743,6392	PDHA1,ACO2,PC,SUCLG1,SDHC,MDH2,ACLY,OGDHL,PCK1,FH,CS,OGDH,IDH3B,DLD,DLST,SDHD
hsa00020	Citrate cycle (TCA cycle)	0.00117604274517244	-6.74560008223052	30	16	0.00896358543417367	1785	6908	5160,50,8802,5091,6391,4191,55753,1431,5105,47,2271,4967,3420,1738,1743,6392	PDHA1,ACO2,SUCLG1,PC,SDHC,MDH2,OGDHL,CS,PCK1,ACLY,FH,OGDH,IDH3B,DLD,DLST,SDHD
hsa00970	Aminoacyl-tRNA biosynthesis	0.00140390165160019	-6.56850002454985	44	21	0.0117647058823529	1785	6908	79731,51520,5188,2617,124454,57505,10667,80222,16,7453,54938,2058,5917,2193,3376,283459,55278,23438,10056,51091,79587	NARS2,LARS,GATB,GARS,EARS2,AARS2,FARS2,TARS2,AARS,WARS,SARS2,EPRS,RARS,FARSA,IARS,GATC,QRSL1,HARS2,FARSB,SEPSECS,CARS2
ko00970	Aminoacyl-tRNA biosynthesis	0.00140390165160019	-6.56850002454985	44	21	0.0117647058823529	1785	6908	79731,5188,51520,2617,124454,57505,10667,16,80222,7453,54938,5917,2058,2193,283459,3376,55278,23438,51091,10056,79587	NARS2,GATB,LARS,GARS,EARS2,AARS2,FARS2,AARS,TARS2,WARS,SARS2,RARS,EPRS,FARSA,GATC,IARS,QRSL1,HARS2,SEPSECS,FARSB,CARS2
ko05168	Herpes simplex infection	0.00146478774815942	-6.52604492881193	184	66	0.0369747899159664	1785	6908	6890,9451,7157,1147,1460,8864,3592,3551,6429,3459,2969,5970,3054,6881,6877,29997,3109,7297,983,6773,6426,3108,8517,1616,5187,406,6772,5500,9575,10454,3122,6884,6908,7186,6431,3134,3133,10482,54205,440275,3105,3725,112950,83860,10189,5601,5781,10379,3717,3107,6885,54926,1936,3150,6502,6430,6875,2353,8772,5430,3569,9519,3190,6428,6878,64135	TAP1,EIF2AK3,TP53,CHUK,CSNK2B,PER2,IL12A,IKBKB,SRSF4,IFNGR1,GTF2I,RELA,HCFC1,TAF10,TAF5,GLTSCR2,HLA-DMB,TYK2,CDK1,STAT2,SRSF1,HLA-DMA,IKBKG,DAXX,PER1,ARNTL,STAT1,PPP1CB,CLOCK,TAB1,HLA-DRA,TAF13,TBP,TRAF2,SRSF6,HLA-F,HLA-E,NXF1,CYCS,EIF2AK4,HLA-A,JUN,MED8,TAF3,ALYREF,MAPK9,PTPN11,IRF9,JAK2,HLA-C,MAP3K7,UBE2R2,EEF1D,HMGN1,SKP2,SRSF5,TAF4B,FOS,FADD,POLR2A,IL6,TBPL1,HNRNPK,SRSF3,TAF6,IFIH1
hsa05168	Herpes simplex infection	0.00146478774815942	-6.52604492881193	184	66	0.0369747899159664	1785	6908	6890,9451,7157,1147,1460,8864,3592,3551,6429,3459,2969,5970,3054,6881,6877,29997,3109,7297,983,6773,6426,3108,8517,1616,5187,406,6772,5500,9575,10454,3122,6884,6908,7186,6431,3134,3133,10482,54205,440275,3105,3725,112950,83860,10189,5601,5781,10379,3717,3107,6885,54926,1936,3150,6502,6430,6875,2353,8772,5430,3569,9519,3190,6428,6878,64135	TAP1,EIF2AK3,TP53,CHUK,CSNK2B,PER2,IL12A,IKBKB,SRSF4,IFNGR1,GTF2I,RELA,HCFC1,TAF10,TAF5,GLTSCR2,HLA-DMB,TYK2,CDK1,STAT2,SRSF1,HLA-DMA,IKBKG,DAXX,PER1,ARNTL,STAT1,PPP1CB,CLOCK,TAB1,HLA-DRA,TAF13,TBP,TRAF2,SRSF6,HLA-F,HLA-E,NXF1,CYCS,EIF2AK4,HLA-A,JUN,MED8,TAF3,ALYREF,MAPK9,PTPN11,IRF9,JAK2,HLA-C,MAP3K7,UBE2R2,EEF1D,HMGN1,SKP2,SRSF5,TAF4B,FOS,FADD,POLR2A,IL6,TBPL1,HNRNPK,SRSF3,TAF6,IFIH1
hsa00240	Pyrimidine metabolism	0.00153670608090837	-6.47811406178947	104	41	0.02296918767507	1785	6908	23649,5440,25885,171568,6240,1723,5424,51728,79077,661,1890,1854,4831,139596,30833,55703,57804,64425,5431,10621,7296,7083,10201,54963,7378,5422,6241,221264,10714,4832,11128,221830,5430,5432,654364,29922,51082,5434,7372,87178,5425	POLA2,POLR2K,POLR1A,POLR3H,RRM1,DHODH,POLD1,POLR3K,DCTPP1,POLR3D,TYMP,DUT,NME2,UPRT,NT5C,POLR3B,POLD4,POLR1E,POLR2B,POLR3F,TXNRD1,TK1,NME6,UCKL1,UPP1,POLA1,RRM2,AK9,POLD3,NME3,POLR3A,TWISTNB,POLR2A,POLR2C,NME1-NME2,NME7,POLR1D,POLR2E,UMPS,PNPT1,POLD2
ko00240	Pyrimidine metabolism	0.00153670608090837	-6.47811406178947	104	41	0.02296918767507	1785	6908	23649,5440,171568,25885,6240,1723,5424,51728,79077,661,1890,1854,4831,139596,30833,55703,57804,64425,5431,10621,7296,7083,10201,7378,5422,54963,6241,221264,10714,4832,5430,11128,221830,5432,654364,29922,51082,5434,7372,87178,5425	POLA2,POLR2K,POLR3H,POLR1A,RRM1,DHODH,POLD1,POLR3K,DCTPP1,POLR3D,TYMP,DUT,NME2,UPRT,NT5C,POLR3B,POLD4,POLR1E,POLR2B,POLR3F,TXNRD1,TK1,NME6,UPP1,POLA1,UCKL1,RRM2,AK9,POLD3,NME3,POLR2A,POLR3A,TWISTNB,POLR2C,NME1-NME2,NME7,POLR1D,POLR2E,UMPS,PNPT1,POLD2
hsa04910	Insulin signaling pathway	0.00159088031971668	-6.44346775576409	139	52	0.0291316526610644	1785	6908	5564,673,6517,3636,2475,9322,5837,5894,5565,5562,5604,10211,5566,1399,805,51763,5770,8651,6464,3551,5296,5601,5105,5584,6194,2997,8503,89801,5256,1977,5261,6199,5170,23433,208,5257,868,5571,3845,92579,2002,6009,572,7248,51422,369,122809,2932,5500,6198,10891,5573	PRKAB1,BRAF,SLC2A4,INPPL1,MTOR,TRIP10,PYGM,RAF1,PRKAB2,PRKAA1,MAP2K1,FLOT1,PRKACA,CRKL,CALM2,INPP5K,PTPN1,SOCS1,SHC1,IKBKB,PIK3R2,MAPK9,PCK1,PRKCI,RPS6,GYS1,PIK3R3,PPP1R3F,PHKA2,EIF4E,PHKG2,RPS6KB2,PDPK1,RHOQ,AKT2,PHKB,CBLB,PRKAG1,KRAS,G6PC3,ELK1,RHEB,BAD,TSC1,PRKAG2,ARAF,SOCS4,GSK3B,PPP1CB,RPS6KB1,PPARGC1A,PRKAR1A
ko04910	Insulin signaling pathway	0.00159088031971668	-6.44346775576409	139	52	0.0291316526610644	1785	6908	5564,673,6517,3636,2475,9322,5837,5894,5565,5562,5604,10211,5566,1399,805,51763,5770,8651,6464,3551,5296,5601,5105,5584,6194,2997,8503,89801,5256,1977,5261,6199,5170,23433,208,5257,868,5571,3845,92579,2002,6009,572,7248,51422,369,122809,2932,5500,6198,10891,5573	PRKAB1,BRAF,SLC2A4,INPPL1,MTOR,TRIP10,PYGM,RAF1,PRKAB2,PRKAA1,MAP2K1,FLOT1,PRKACA,CRKL,CALM2,INPP5K,PTPN1,SOCS1,SHC1,IKBKB,PIK3R2,MAPK9,PCK1,PRKCI,RPS6,GYS1,PIK3R3,PPP1R3F,PHKA2,EIF4E,PHKG2,RPS6KB2,PDPK1,RHOQ,AKT2,PHKB,CBLB,PRKAG1,KRAS,G6PC3,ELK1,RHEB,BAD,TSC1,PRKAG2,ARAF,SOCS4,GSK3B,PPP1CB,RPS6KB1,PPARGC1A,PRKAR1A
hsa03460	Fanconi anemia pathway	0.00164900842387306	-6.40758112694406	53	24	0.0134453781512605	1785	6908	3280,2067,8940,2176,83990,2177,7156,4292,641,57697,2189,55215,57599,6118,5980,5889,675,29089,80233,91442,11201,84126,545,7398	HES1,ERCC1,TOP3B,FANCC,BRIP1,FANCD2,TOP3A,MLH1,BLM,FANCM,FANCG,FANCI,WDR48,RPA2,REV3L,RAD51C,BRCA2,UBE2T,FAAP100,FAAP24,POLI,ATRIP,ATR,USP1
ko03460	Fanconi anemia pathway	0.00164900842387306	-6.40758112694406	53	24	0.0134453781512605	1785	6908	3280,2067,8940,2176,83990,2177,7156,4292,641,57697,2189,55215,57599,6118,5980,5889,675,29089,80233,91442,11201,84126,545,7398	HES1,ERCC1,TOP3B,FANCC,BRIP1,FANCD2,TOP3A,MLH1,BLM,FANCM,FANCG,FANCI,WDR48,RPA2,REV3L,RAD51C,BRCA2,UBE2T,FAAP100,FAAP24,POLI,ATRIP,ATR,USP1
ko05210	Colorectal cancer	0.00177710719915229	-6.33276840571341	62	27	0.0151260504201681	1785	6908	673,5894,208,842,5604,7157,5900,3845,324,54205,4292,2353,6934,572,3725,595,369,1499,332,4609,5601,5296,4436,581,8503,2932,2956	BRAF,RAF1,AKT2,CASP9,MAP2K1,TP53,RALGDS,KRAS,APC,CYCS,MLH1,FOS,TCF7L2,BAD,JUN,CCND1,ARAF,CTNNB1,BIRC5,MYC,MAPK9,PIK3R2,MSH2,BAX,PIK3R3,GSK3B,MSH6
hsa05210	Colorectal cancer	0.00177710719915229	-6.33276840571341	62	27	0.0151260504201681	1785	6908	673,5894,208,842,5604,7157,5900,3845,324,54205,4292,2353,6934,572,3725,595,369,1499,332,4609,5601,5296,4436,581,8503,2932,2956	BRAF,RAF1,AKT2,CASP9,MAP2K1,TP53,RALGDS,KRAS,APC,CYCS,MLH1,FOS,TCF7L2,BAD,JUN,CCND1,ARAF,CTNNB1,BIRC5,MYC,MAPK9,PIK3R2,MSH2,BAX,PIK3R3,GSK3B,MSH6
hsa04710	Circadian rhythm	0.00185353081250783	-6.29066291155276	31	16	0.00896358543417367	1785	6908	5564,23291,1454,5565,5562,5571,8553,8864,51422,79365,5187,406,1408,9575,9572,8945	PRKAB1,FBXW11,CSNK1E,PRKAB2,PRKAA1,PRKAG1,BHLHE40,PER2,PRKAG2,BHLHE41,PER1,ARNTL,CRY2,CLOCK,NR1D1,BTRC
ko04710	Circadian rhythm	0.00185353081250783	-6.29066291155276	31	16	0.00896358543417367	1785	6908	5564,23291,1454,5565,5562,5571,8553,8864,51422,79365,5187,406,1408,9575,9572,8945	PRKAB1,FBXW11,CSNK1E,PRKAB2,PRKAA1,PRKAG1,BHLHE40,PER2,PRKAG2,BHLHE41,PER1,ARNTL,CRY2,CLOCK,NR1D1,BTRC
hsa01100	Metabolic pathways	0.00219108545493059	-6.1233582164226	1214	354	0.198319327731092	1785	6908	197258,4712,5837,10554,2639,8867,51728,6484,1890,517,4124,51102,139596,54995,1738,4705,5160,2954,124454,7378,6609,2271,63917,80142,5432,5372,5198,3703,226,9377,7388,6483,8704,10005,4729,4594,4329,5440,6480,79087,171568,5428,84890,1718,26229,6240,81579,54205,51477,4507,374291,55512,51763,6184,5298,6307,1603,10476,23545,201595,1537,57804,55967,5631,64087,6611,3156,2222,66008,5279,5625,51604,594,5422,11253,157506,3615,8394,138050,9517,4548,221830,55361,159,51601,2058,10797,57494,283871,29922,47,7372,5224,85365,55627,55748,1717,686,51540,2582,5188,9374,523,55500,521,83440,253558,1040,4709,80308,440,9110,65263,1854,30833,441024,2597,1350,6303,1353,535,4701,221264,11232,6392,221,1650,10400,5033,440138,2710,4837,593,6391,10905,84245,1723,506,10654,5281,2937,10682,27430,79077,661,3157,283459,10606,79868,1349,4696,3613,58478,55163,10632,6470,7083,5289,10678,2987,29968,56895,3939,29071,5430,654364,3033,5091,5230,51,199857,138429,57678,4725,384,23649,7381,25885,7358,91012,9197,56922,162466,1798,9388,9487,23382,1595,7385,3032,4831,231,3373,4731,55703,4700,529,4720,51056,6241,56267,84720,1743,93100,29926,10327,10195,2744,10555,10855,5051,8942,55278,5049,55568,200895,9054,1340,80025,204,84803,79053,427,128869,9249,1119,8659,56913,2356,4708,5105,53630,5805,29920,5277,5832,51606,6309,64425,9114,224,5431,10621,516,337876,85465,10201,669,5471,262,2629,3295,144193,26035,5226,5980,6675,51082,2224,5434,27349,498,3145,5425,65220,11112,4351,4698,55349,8802,7360,4191,8527,64900,54539,5424,9453,51079,7386,3422,1431,6185,2805,10768,10558,23193,326625,144245,1491,84274,25796,55312,8705,27089,54963,4597,4967,514,4832,64850,27010,513,5743,5445,50,8372,210,126328,4694,4128,29925,4713,56848,1716,5723,22934,55191,8681,6652,10020,3633,5373,51004,2618,883,4723,64768,1337,253430,501,4728,10728,1629,1373,2990,2729,55753,133686,9551,92579,10714,5498,11128,51382,9,1351,3614,528,3420,112483,8310,5130,2653,2135	FUK,NDUFB6,PYGM,AGPAT1,GCDH,SYNJ1,POLR3K,ST3GAL4,TYMP,ATP5G2,MAN2A1,MECR,UPRT,OXSM,DLD,NDUFA10,PDHA1,GSTZ1,EARS2,UPP1,SMPD1,FH,GALNT11,PTGES2,POLR2C,PMM1,PFAS,STT3A,ALDOA,COX5A,UQCRH,ST3GAL2,B4GALT2,ACOT8,NDUFV2,MUT,ALDH6A1,POLR2K,ST6GAL1,ALG12,POLR3H,POLG,ADO,DHCR24,B3GAT3,RRM1,PLA2G12A,CYCS,ISYNA1,MTAP,NDUFS7,SMPD3,INPP5K,RPN1,PI4KB,MSMO1,DAD1,ATP5H,ATP6V0A2,STT3B,CYC1,POLD4,NDUFA12,PRPS1,MCCC2,SMS,HMGCR,FDFT1,TRAK2,PIGC,PRODH,PIGT,BCKDHB,POLA1,MAN1B1,RDH10,IMPDH2,PIP5K1A,HGSNAT,SPTLC2,MTR,TWISTNB,PI4K2A,ADSS,LIPT1,EPRS,MTHFD2,RIMKLB,PGP,NME7,ACLY,UMPS,PGAM2,ALG2,SMPD4,CNDP2,DHCR7,BTD,SCLY,GALE,GATB,PPT2,ATP6V1A,ETNK1,ATP5I,ADPGK,LCLAT1,CDS1,NDUFB3,FLAD1,ASNS,MTMR4,PYCRL,DUT,NT5C,MTHFD2L,GAPDH,COX7C,SAT1,COX11,ATP6V0A1,NDUFA7,AK9,POLG2,SDHD,ALDH3B1,DDOST,PEMT,P4HA1,ALG11,GK,NNMT,BCKDHA,SDHC,MAN1A2,MRI1,DHODH,ATP5B,PMVK,PIGF,GSS,EBP,MAT2B,DCTPP1,POLR3D,HMGCS1,GATC,PAICS,ALG13,COX7B,NDUFA3,IMPA2,ENOPH1,PNPO,ATP5L,SHMT1,TK1,PIK3C3,B3GNT2,GUK1,PSAT1,AGPAT4,LDHA,C1GALT1C1,POLR2A,NME1-NME2,HADH,PC,PGK1,ACOX1,ALG14,PIP5KL1,GPAM,NDUFS5,ARG2,POLA2,UQCRB,POLR1A,UGDH,CERS5,SLC33A1,MCCC1,PHOSPHO1,DPAGT1,LIPG,PIGL,AHCYL2,CYP51A1,UQCRC2,HADHB,NME2,AKR1B1,HYAL1,NDUFV3,POLR3B,NDUFA6,ATP6V1E1,NDUFS2,LAP3,RRM2,CCBL2,PIGO,DLST,NAPRT,GMPPA,AKR1A1,ALG3,GLS,AGPAT2,HPSE,PAFAH2,KYNU,QRSL1,PAFAH1B2,GALNT10,DHFRL1,NFS1,COX6B1,PANK2,AK2,GPAT3,ALG8,ASAH1,PIGU,DHRS3,CHKA,ALDH4A1,C1GALT1,FPGS,NDUFB2,PCK1,BCO1,PTS,PYCR2,PIGA,ALDH18A1,ATP6V1H,SC5D,POLR1E,ATP6V0D1,ALDH3A2,POLR2B,POLR3F,ATP5G1,CHSY3,EPT1,NME6,BPGM,PPAT,AMD1,GBA,HSD17B4,AMDHD1,GLCE,PGD,REV3L,UAP1,POLR1D,FDPS,POLR2E,MCAT,ATP5A1,HMBS,POLD2,NADK,HIBADH,MPI,NDUFA5,CHDH,SUCLG1,UGP2,MDH2,DGKD,LPIN3,NDUFB11,POLD1,GGPS1,NDUFA13,UQCRFS1,IDI1,CS,RPN2,GOT1,AHCYL1,SPTLC1,GANAB,MMAB,ALG10B,CTH,COQ5,PGLS,RFK,B3GALT4,UQCRQ,UCKL1,MVD,OGDH,ATP5E,NME3,ETNPPL,TPK1,ATP5D,PTGS2,PON2,ACO2,HYAL3,ALAD,NDUFA11,NDUFA1,MAOA,GMPPB,NDUFB7,SPHK2,DGUOK,PSPH,RPIA,NADSYN1,JMJD7-PLA2G4B,SORD,GNE,INPP5B,PMM2,COQ6,GART,CCBL1,NDUFV1,IPPK,COX6A1,IPMK,ALDH7A1,NDUFS8,PTGES3,DBT,CPS1,GUSB,GCLC,OGDHL,NADK2,ATP5J2,G6PC3,POLD3,PPOX,POLR3A,ATP6V1D,NAT1,COX8A,IMPDH1,ATP6V1C1,IDH3B,SAT2,ACOX3,PCYT1A,GCSH,EXTL2
hsa01130	Biosynthesis of antibiotics	0.00223358757755976	-6.10414620703428	210	73	0.0408963585434174	1785	6908	384,9986,7360,8802,4191,83440,2639,9453,1595,3422,65263,1431,3032,4831,2805,1738,1491,5160,2597,25796,4597,2271,4967,221264,1743,4832,6392,10327,10269,50,5051,5198,226,5723,22934,204,6391,593,51477,2618,3157,6307,10606,5105,501,29920,6309,1629,224,5631,2222,3156,5625,6470,10201,29968,669,5471,594,55753,3939,5226,654364,6675,29922,283871,3033,5230,2224,47,5224,3420,2653	ARG2,RCE1,UGP2,SUCLG1,MDH2,ADPGK,GCDH,GGPS1,CYP51A1,IDI1,PYCRL,CS,HADHB,NME2,GOT1,DLD,CTH,PDHA1,GAPDH,PGLS,MVD,FH,OGDH,AK9,DLST,NME3,SDHD,AKR1A1,ZMPSTE24,ACO2,PAFAH2,PFAS,ALDOA,PSPH,RPIA,AK2,SDHC,BCKDHA,ISYNA1,GART,HMGCS1,MSMO1,PAICS,PCK1,ALDH7A1,PYCR2,SC5D,DBT,ALDH3A2,PRPS1,FDFT1,HMGCR,PRODH,SHMT1,NME6,PSAT1,BPGM,PPAT,BCKDHB,OGDHL,LDHA,PGD,NME1-NME2,UAP1,NME7,PGP,HADH,PGK1,FDPS,ACLY,PGAM2,IDH3B,GCSH
ko00510	N-Glycan biosynthesis	0.00290006252409448	-5.84302298218954	49	22	0.0123249299719888	1785	6908	10905,6480,79087,11253,79053,1798,10195,6184,1650,3703,199857,79868,57171,1603,4124,440138,6185,201595,85365,23193,8704,144245	MAN1A2,ST6GAL1,ALG12,MAN1B1,ALG8,DPAGT1,ALG3,RPN1,DDOST,STT3A,ALG14,ALG13,DOLPP1,DAD1,MAN2A1,ALG11,RPN2,STT3B,ALG2,GANAB,B4GALT2,ALG10B
hsa00510	N-Glycan biosynthesis	0.00290006252409448	-5.84302298218954	49	22	0.0123249299719888	1785	6908	10905,6480,79087,11253,79053,1798,10195,6184,1650,3703,57171,1603,79868,199857,4124,440138,6185,201595,85365,23193,8704,144245	MAN1A2,ST6GAL1,ALG12,MAN1B1,ALG8,DPAGT1,ALG3,RPN1,DDOST,STT3A,DOLPP1,DAD1,ALG13,ALG14,MAN2A1,ALG11,RPN2,STT3B,ALG2,GANAB,B4GALT2,ALG10B
hsa05220	Chronic myeloid leukemia	0.00302749798666094	-5.80001874755428	73	30	0.0168067226890756	1785	6908	673,1019,5894,208,5604,7157,868,1871,3845,1147,6777,1488,598,572,1399,595,8517,369,6464,4609,3551,5296,5781,8503,1027,1870,5970,1021,3066,1029	BRAF,CDK4,RAF1,AKT2,MAP2K1,TP53,CBLB,E2F3,KRAS,CHUK,STAT5B,CTBP2,BCL2L1,BAD,CRKL,CCND1,IKBKG,ARAF,SHC1,MYC,IKBKB,PIK3R2,PTPN11,PIK3R3,CDKN1B,E2F2,RELA,CDK6,HDAC2,CDKN2A
ko05220	Chronic myeloid leukemia	0.00302749798666094	-5.80001874755428	73	30	0.0168067226890756	1785	6908	673,1019,5894,208,5604,7157,868,1871,3845,1147,6777,1488,598,572,1399,595,8517,369,6464,4609,3551,5296,5781,8503,1027,1870,5970,1021,3066,1029	BRAF,CDK4,RAF1,AKT2,MAP2K1,TP53,CBLB,E2F3,KRAS,CHUK,STAT5B,CTBP2,BCL2L1,BAD,CRKL,CCND1,IKBKG,ARAF,SHC1,MYC,IKBKB,PIK3R2,PTPN11,PIK3R3,CDKN1B,E2F2,RELA,CDK6,HDAC2,CDKN2A
hsa05166	HTLV-I infection	0.00379199325720857	-5.57486347275324	258	86	0.0481792717086835	1785	6908	5423,9232,7157,1147,324,6777,598,821,2535,5424,5566,1390,595,5111,1499,3551,5296,10393,5971,8503,51434,4791,1386,5970,1856,8321,4215,468,208,1019,991,3109,1871,701,467,8697,7416,3108,8517,4488,7514,4085,6722,2932,11200,8061,1870,3122,1030,51433,1958,7094,6908,3133,3134,6929,1111,3105,811,3725,466,4609,80326,581,545,3107,57804,6237,29882,3845,2002,10714,2353,55697,200186,2114,996,2874,3569,2224,7494,9519,4776,9133,1029,5425	POLB,PTTG1,TP53,CHUK,APC,STAT5B,BCL2L1,CANX,FZD2,POLD1,PRKACA,CREM,CCND1,PCNA,CTNNB1,IKBKB,PIK3R2,ANAPC10,RELB,PIK3R3,ANAPC7,NFKB2,ATF2,RELA,DVL2,FZD1,MAP3K3,ATF4,AKT2,CDK4,CDC20,HLA-DMB,E2F3,BUB1B,ATF3,CDC23,VDAC1,HLA-DMA,IKBKG,MSX2,XPO1,MAD2L1,SRF,GSK3B,CHEK2,FOSL1,E2F2,HLA-DRA,CDKN2B,ANAPC5,EGR1,TLN1,TBP,HLA-E,HLA-F,TCF3,CHEK1,HLA-A,CALR,JUN,ATF1,MYC,WNT10A,BAX,ATR,HLA-C,POLD4,RRAS,ANAPC2,KRAS,ELK1,POLD3,FOS,VAC14,CRTC2,ETS2,CDC27,GPS2,IL6,FDPS,XBP1,TBPL1,NFATC4,CCNB2,CDKN2A,POLD2
ko05166	HTLV-I infection	0.00379199325720857	-5.57486347275324	258	86	0.0481792717086835	1785	6908	5423,9232,7157,1147,324,6777,598,821,2535,5424,5566,1390,595,5111,1499,3551,5296,10393,5971,8503,51434,4791,1386,5970,1856,8321,4215,468,208,1019,991,3109,1871,701,467,8697,7416,3108,8517,4488,7514,4085,6722,2932,11200,8061,1870,3122,1030,51433,1958,7094,6908,3133,3134,6929,1111,3105,811,3725,466,4609,80326,581,545,3107,57804,6237,29882,3845,2002,10714,2353,55697,200186,2114,996,2874,3569,2224,7494,9519,4776,9133,1029,5425	POLB,PTTG1,TP53,CHUK,APC,STAT5B,BCL2L1,CANX,FZD2,POLD1,PRKACA,CREM,CCND1,PCNA,CTNNB1,IKBKB,PIK3R2,ANAPC10,RELB,PIK3R3,ANAPC7,NFKB2,ATF2,RELA,DVL2,FZD1,MAP3K3,ATF4,AKT2,CDK4,CDC20,HLA-DMB,E2F3,BUB1B,ATF3,CDC23,VDAC1,HLA-DMA,IKBKG,MSX2,XPO1,MAD2L1,SRF,GSK3B,CHEK2,FOSL1,E2F2,HLA-DRA,CDKN2B,ANAPC5,EGR1,TLN1,TBP,HLA-E,HLA-F,TCF3,CHEK1,HLA-A,CALR,JUN,ATF1,MYC,WNT10A,BAX,ATR,HLA-C,POLD4,RRAS,ANAPC2,KRAS,ELK1,POLD3,FOS,VAC14,CRTC2,ETS2,CDC27,GPS2,IL6,FDPS,XBP1,TBPL1,NFATC4,CCNB2,CDKN2A,POLD2
ko03410	Base excision repair	0.0041916051959957	-5.47467151674318	33	16	0.00896358543417367	1785	6908	3146,5423,4913,10038,3978,10714,5424,7515,5111,79661,6996,27301,57804,4595,5425,2237	HMGB1,POLB,NTHL1,PARP2,LIG1,POLD3,POLD1,XRCC1,PCNA,NEIL1,TDG,APEX2,POLD4,MUTYH,POLD2,FEN1
hsa03410	Base excision repair	0.0041916051959957	-5.47467151674318	33	16	0.00896358543417367	1785	6908	3146,5423,4913,10038,3978,10714,5424,7515,6996,5111,79661,27301,57804,4595,2237,5425	HMGB1,POLB,NTHL1,PARP2,LIG1,POLD3,POLD1,XRCC1,TDG,PCNA,NEIL1,APEX2,POLD4,MUTYH,FEN1,POLD2
hsa04152	AMPK signaling pathway	0.00516325130437562	-5.26618880016969	123	45	0.0252100840336134	1785	6908	64764,51552,5564,6517,2475,9230,5565,79966,5562,79602,5526,84335,595,4218,890,1938,5518,5296,5105,2997,8503,5521,6885,3156,6199,5170,23411,148327,5208,208,5571,5209,92579,10890,6009,200186,7248,5529,51422,1994,5527,81617,6198,10891,5528	CREB3L2,RAB14,PRKAB1,SLC2A4,MTOR,RAB11B,PRKAB2,SCD5,PRKAA1,ADIPOR2,PPP2R5B,AKT1S1,CCND1,RAB8A,CCNA2,EEF2,PPP2R1A,PIK3R2,PCK1,GYS1,PIK3R3,PPP2R2B,MAP3K7,HMGCR,RPS6KB2,PDPK1,SIRT1,CREB3L4,PFKFB2,AKT2,PRKAG1,PFKFB3,G6PC3,RAB10,RHEB,CRTC2,TSC1,PPP2R5E,PRKAG2,ELAVL1,PPP2R5C,CAB39L,RPS6KB1,PPARGC1A,PPP2R5D
ko04152	AMPK signaling pathway	0.00516325130437562	-5.26618880016969	123	45	0.0252100840336134	1785	6908	64764,51552,5564,6517,2475,9230,5565,79966,5562,79602,5526,84335,595,4218,890,1938,5518,5296,5105,2997,8503,5521,6885,3156,6199,5170,23411,148327,5208,208,5571,5209,92579,10890,6009,200186,7248,5529,51422,1994,5527,81617,6198,10891,5528	CREB3L2,RAB14,PRKAB1,SLC2A4,MTOR,RAB11B,PRKAB2,SCD5,PRKAA1,ADIPOR2,PPP2R5B,AKT1S1,CCND1,RAB8A,CCNA2,EEF2,PPP2R1A,PIK3R2,PCK1,GYS1,PIK3R3,PPP2R2B,MAP3K7,HMGCR,RPS6KB2,PDPK1,SIRT1,CREB3L4,PFKFB2,AKT2,PRKAG1,PFKFB3,G6PC3,RAB10,RHEB,CRTC2,TSC1,PPP2R5E,PRKAG2,ELAVL1,PPP2R5C,CAB39L,RPS6KB1,PPARGC1A,PPP2R5D
ko03020	RNA polymerase	0.0056416268749064	-5.17758280206915	31	15	0.00840336134453781	1785	6908	5432,661,51082,5440,171568,25885,5434,55703,51728,64425,5430,11128,5431,221830,10621	POLR2C,POLR3D,POLR1D,POLR2K,POLR3H,POLR1A,POLR2E,POLR3B,POLR3K,POLR1E,POLR2A,POLR3A,POLR2B,TWISTNB,POLR3F
hsa03020	RNA polymerase	0.0056416268749064	-5.17758280206915	31	15	0.00840336134453781	1785	6908	5432,661,51082,5440,25885,171568,5434,55703,64425,51728,11128,5431,221830,5430,10621	POLR2C,POLR3D,POLR1D,POLR2K,POLR1A,POLR3H,POLR2E,POLR3B,POLR1E,POLR3K,POLR3A,POLR2B,TWISTNB,POLR2A,POLR3F
hsa05222	Small cell lung cancer	0.00687698834504647	-4.97957446341882	86	33	0.0184873949579832	1785	6908	1030,2335,7186,7157,54205,1147,598,329,3914,595,4609,3551,5296,1163,8503,1027,5970,1021,1164,5915,330,208,1019,842,6502,1871,6257,8517,5743,3688,1870,9618,1288	CDKN2B,FN1,TRAF2,TP53,CYCS,CHUK,BCL2L1,BIRC2,LAMB3,CCND1,MYC,IKBKB,PIK3R2,CKS1B,PIK3R3,CDKN1B,RELA,CDK6,CKS2,RARB,BIRC3,AKT2,CDK4,CASP9,SKP2,E2F3,RXRB,IKBKG,PTGS2,ITGB1,E2F2,TRAF4,COL4A6
ko05222	Small cell lung cancer	0.00687698834504647	-4.97957446341882	86	33	0.0184873949579832	1785	6908	1030,2335,7186,7157,54205,1147,598,329,3914,595,4609,3551,5296,1163,8503,1027,5970,1021,1164,5915,330,208,1019,842,6502,1871,6257,8517,5743,3688,1870,9618,1288	CDKN2B,FN1,TRAF2,TP53,CYCS,CHUK,BCL2L1,BIRC2,LAMB3,CCND1,MYC,IKBKB,PIK3R2,CKS1B,PIK3R3,CDKN1B,RELA,CDK6,CKS2,RARB,BIRC3,AKT2,CDK4,CASP9,SKP2,E2F3,RXRB,IKBKG,PTGS2,ITGB1,E2F2,TRAF4,COL4A6
hsa04914	Progesterone-mediated oocyte maturation	0.00839308893891885	-4.7803466571404	87	33	0.0184873949579832	1785	6908	51433,673,80315,5894,5604,22849,5566,6196,890,5296,51343,5601,10393,8379,8503,51434,3320,2771,993,25847,208,3326,29882,3845,8697,2773,995,983,996,369,4085,9133,132864	ANAPC5,BRAF,CPEB4,RAF1,MAP2K1,CPEB3,PRKACA,RPS6KA2,CCNA2,PIK3R2,FZR1,MAPK9,ANAPC10,MAD1L1,PIK3R3,ANAPC7,HSP90AA1,GNAI2,CDC25A,ANAPC13,AKT2,HSP90AB1,ANAPC2,KRAS,CDC23,GNAI3,CDC25C,CDK1,CDC27,ARAF,MAD2L1,CCNB2,CPEB2
ko04914	Progesterone-mediated oocyte maturation	0.00839308893891885	-4.7803466571404	87	33	0.0184873949579832	1785	6908	51433,673,80315,5894,5604,22849,5566,6196,890,5296,51343,5601,10393,8379,8503,51434,3320,2771,993,25847,208,3326,29882,3845,8697,2773,995,983,996,369,4085,9133,132864	ANAPC5,BRAF,CPEB4,RAF1,MAP2K1,CPEB3,PRKACA,RPS6KA2,CCNA2,PIK3R2,FZR1,MAPK9,ANAPC10,MAD1L1,PIK3R3,ANAPC7,HSP90AA1,GNAI2,CDC25A,ANAPC13,AKT2,HSP90AB1,ANAPC2,KRAS,CDC23,GNAI3,CDC25C,CDK1,CDC27,ARAF,MAD2L1,CCNB2,CPEB2
ko05034	Alcoholism	0.0124265423404363	-4.38792058267612	179	60	0.0336134453781513	1785	6908	64764,673,3015,1388,8367,5894,55766,5604,85235,8350,2030,10013,8969,5566,2783,8347,317772,8360,440689,8329,8365,805,6464,8364,2354,653604,51764,8520,8332,2771,1386,3017,2787,8331,8336,627,468,148327,723790,2788,85236,3845,3021,8363,8340,8368,94239,2773,10014,8330,3012,8362,369,9759,59345,3014,5500,4128,128312,3066	CREB3L2,BRAF,H2AFZ,ATF6B,HIST1H4E,RAF1,H2AFJ,MAP2K1,HIST1H2AH,HIST1H3A,SLC29A1,HDAC6,HIST1H2AG,PRKACA,GNB2,HIST1H2BC,HIST2H2AB,HIST1H4D,HIST2H2BF,HIST1H2AI,HIST1H4H,CALM2,SHC1,HIST1H4C,FOSB,HIST2H3D,GNG13,HAT1,HIST1H2AL,GNAI2,ATF2,HIST1H2BD,GNG5,HIST1H2AJ,HIST1H2AM,BDNF,ATF4,CREB3L4,HIST2H2AA4,GNG7,HIST1H2BK,KRAS,H3F3B,HIST1H4J,HIST1H2BL,HIST1H4L,H2AFV,GNAI3,HDAC5,HIST1H2AK,HIST1H2AE,HIST1H4K,ARAF,HDAC4,GNB4,H2AFX,PPP1CB,MAOA,HIST3H2BB,HDAC2
hsa05034	Alcoholism	0.0124265423404363	-4.38792058267612	179	60	0.0336134453781513	1785	6908	64764,673,3015,1388,8367,5894,55766,5604,85235,8350,2030,10013,8969,5566,2783,8347,317772,8360,440689,8329,8365,805,6464,8364,2354,653604,51764,8520,8332,2771,1386,3017,2787,8331,8336,627,468,148327,723790,2788,85236,3845,3021,8363,8340,8368,94239,2773,10014,8330,3012,8362,369,9759,59345,3014,5500,4128,128312,3066	CREB3L2,BRAF,H2AFZ,ATF6B,HIST1H4E,RAF1,H2AFJ,MAP2K1,HIST1H2AH,HIST1H3A,SLC29A1,HDAC6,HIST1H2AG,PRKACA,GNB2,HIST1H2BC,HIST2H2AB,HIST1H4D,HIST2H2BF,HIST1H2AI,HIST1H4H,CALM2,SHC1,HIST1H4C,FOSB,HIST2H3D,GNG13,HAT1,HIST1H2AL,GNAI2,ATF2,HIST1H2BD,GNG5,HIST1H2AJ,HIST1H2AM,BDNF,ATF4,CREB3L4,HIST2H2AA4,GNG7,HIST1H2BK,KRAS,H3F3B,HIST1H4J,HIST1H2BL,HIST1H4L,H2AFV,GNAI3,HDAC5,HIST1H2AK,HIST1H2AE,HIST1H4K,ARAF,HDAC4,GNB4,H2AFX,PPP1CB,MAOA,HIST3H2BB,HDAC2
ko00900	Terpenoid backbone biosynthesis	0.012765189943728	-4.36103334835804	22	11	0.0061624649859944	1785	6908	79947,3157,3422,9986,4597,2224,10654,9453,57107,3156,10269	DHDDS,HMGCS1,IDI1,RCE1,MVD,FDPS,PMVK,GGPS1,PDSS2,HMGCR,ZMPSTE24
hsa00900	Terpenoid backbone biosynthesis	0.012765189943728	-4.36103334835804	22	11	0.0061624649859944	1785	6908	79947,3422,3157,9986,4597,2224,10654,9453,57107,3156,10269	DHDDS,IDI1,HMGCS1,RCE1,MVD,FDPS,PMVK,GGPS1,PDSS2,HMGCR,ZMPSTE24
hsa05131	Shigellosis	0.0135498834179505	-4.30137733553473	64	25	0.0140056022408964	1785	6908	10163,23291,8936,8767,1147,10552,1729,199746,1399,8517,998,63916,8976,7307,3551,5601,7322,3688,2017,10109,9474,7414,5970,9475,8945	WASF2,FBXW11,WASF1,RIPK2,CHUK,ARPC1A,DIAPH1,U2AF1L4,CRKL,IKBKG,CDC42,ELMO2,WASL,U2AF1,IKBKB,MAPK9,UBE2D2,ITGB1,CTTN,ARPC2,ATG5,VCL,RELA,ROCK2,BTRC
hsa05161	Hepatitis B	0.0139259486710997	-4.27400136830085	146	50	0.0280112044817927	1785	6908	64764,1388,5894,5604,7157,1147,6777,54205,1960,595,3725,5111,890,4609,3551,5296,5601,581,1027,8503,1386,6774,5970,1021,1643,468,148327,208,1019,842,1871,10971,3845,2002,2353,6773,8772,1654,572,8517,332,3569,6778,6772,2185,7534,4776,64135,1870,1642	CREB3L2,ATF6B,RAF1,MAP2K1,TP53,CHUK,STAT5B,CYCS,EGR3,CCND1,JUN,PCNA,CCNA2,MYC,IKBKB,PIK3R2,MAPK9,BAX,CDKN1B,PIK3R3,ATF2,STAT3,RELA,CDK6,DDB2,ATF4,CREB3L4,AKT2,CDK4,CASP9,E2F3,YWHAQ,KRAS,ELK1,FOS,STAT2,FADD,DDX3X,BAD,IKBKG,BIRC5,IL6,STAT6,STAT1,PTK2B,YWHAZ,NFATC4,IFIH1,E2F2,DDB1
hsa05213	Endometrial cancer	0.0150564380709183	-4.19594960045996	52	21	0.0117647058823529	1785	6908	5170,673,1495,5894,208,842,5604,7157,3845,324,4292,2002,6934,572,595,369,1499,4609,5296,8503,2932	PDPK1,BRAF,CTNNA1,RAF1,AKT2,CASP9,MAP2K1,TP53,KRAS,APC,MLH1,ELK1,TCF7L2,BAD,CCND1,ARAF,CTNNB1,MYC,PIK3R2,PIK3R3,GSK3B
ko05213	Endometrial cancer	0.0150564380709183	-4.19594960045996	52	21	0.0117647058823529	1785	6908	5170,673,1495,5894,208,842,5604,7157,3845,324,4292,2002,6934,572,595,369,1499,4609,5296,8503,2932	PDPK1,BRAF,CTNNA1,RAF1,AKT2,CASP9,MAP2K1,TP53,KRAS,APC,MLH1,ELK1,TCF7L2,BAD,CCND1,ARAF,CTNNB1,MYC,PIK3R2,PIK3R3,GSK3B
ko04140	Regulation of autophagy	0.0271472187643645	-3.60648067746774	39	16	0.00896358543417367	1785	6908	84938,5289,89849,11337,64422,55054,5562,10533,30849,9140,9776,9474,23192,8678,115201,23710	ATG4C,PIK3C3,ATG16L2,GABARAP,ATG3,ATG16L1,PRKAA1,ATG7,PIK3R4,ATG12,ATG13,ATG5,ATG4B,BECN1,ATG4A,GABARAPL1
hsa04140	Regulation of autophagy	0.0271472187643645	-3.60648067746774	39	16	0.00896358543417367	1785	6908	84938,5289,89849,11337,64422,55054,5562,10533,30849,9140,9776,9474,23192,8678,115201,23710	ATG4C,PIK3C3,ATG16L2,GABARAP,ATG3,ATG16L1,PRKAA1,ATG7,PIK3R4,ATG12,ATG13,ATG5,ATG4B,BECN1,ATG4A,GABARAPL1
hsa04931	Insulin resistance	0.0294719446600835	-3.52431649662261	111	38	0.0212885154061625	1785	6908	64764,5564,6517,5837,2475,5565,5562,10062,7376,5581,6196,6945,5770,3551,5296,5601,5105,10724,5781,2997,8503,6774,5970,6199,5170,148327,208,5571,92579,200186,51422,3569,8473,5500,2932,6198,10891,9882	CREB3L2,PRKAB1,SLC2A4,PYGM,MTOR,PRKAB2,PRKAA1,NR1H3,NR1H2,PRKCE,RPS6KA2,MLX,PTPN1,IKBKB,PIK3R2,MAPK9,PCK1,MGEA5,PTPN11,GYS1,PIK3R3,STAT3,RELA,RPS6KB2,PDPK1,CREB3L4,AKT2,PRKAG1,G6PC3,CRTC2,PRKAG2,IL6,OGT,PPP1CB,GSK3B,RPS6KB1,PPARGC1A,TBC1D4
hsa04115	p53 signaling pathway	0.0299879170460747	-3.50696074358249	68	25	0.0140056022408964	1785	6908	1643,55367,1019,3732,8493,842,7157,4194,6241,1111,51246,54205,56475,983,595,5366,4616,9538,581,545,11200,9133,1021,1029,901	DDB2,PIDD1,CDK4,CD82,PPM1D,CASP9,TP53,MDM4,RRM2,CHEK1,SHISA5,CYCS,RPRM,CDK1,CCND1,PMAIP1,GADD45B,EI24,BAX,ATR,CHEK2,CCNB2,CDK6,CDKN2A,CCNG2
ko04115	p53 signaling pathway	0.0299879170460747	-3.50696074358249	68	25	0.0140056022408964	1785	6908	1643,55367,1019,3732,8493,842,7157,4194,6241,1111,51246,54205,56475,983,595,5366,4616,9538,581,545,11200,9133,1021,1029,901	DDB2,PIDD1,CDK4,CD82,PPM1D,CASP9,TP53,MDM4,RRM2,CHEK1,SHISA5,CYCS,RPRM,CDK1,CCND1,PMAIP1,GADD45B,EI24,BAX,ATR,CHEK2,CCNB2,CDK6,CDKN2A,CCNG2
ko04130	SNARE interactions in vesicular transport	0.0363317549842575	-3.31506312716493	34	14	0.00784313725490196	1785	6908	55850,8677,6843,53407,9341,143187,9554,10282,10490,6810,9527,8675,6811,10228	USE1,STX10,VAMP1,STX18,VAMP3,VTI1A,SEC22B,BET1,VTI1B,STX4,GOSR1,STX16,STX5,STX6
hsa04130	SNARE interactions in vesicular transport	0.0363317549842575	-3.31506312716493	34	14	0.00784313725490196	1785	6908	55850,8677,6843,53407,9341,143187,9554,10282,10490,6810,9527,8675,6811,10228	USE1,STX10,VAMP1,STX18,VAMP3,VTI1A,SEC22B,BET1,VTI1B,STX4,GOSR1,STX16,STX5,STX6
ko04962	Vasopressin-regulated water reabsorption	0.042086262351119	-3.16803390149414	44	17	0.00952380952380952	1785	6908	64764,1781,148327,9230,8655,10540,5868,84516,6810,5869,5566,8766,10671,51164,51626,5878,1639	CREB3L2,DYNC1I2,CREB3L4,RAB11B,DYNLL1,DCTN2,RAB5A,DCTN5,STX4,RAB5B,PRKACA,RAB11A,DCTN6,DCTN4,DYNC2LI1,RAB5C,DCTN1
hsa04962	Vasopressin-regulated water reabsorption	0.042086262351119	-3.16803390149414	44	17	0.00952380952380952	1785	6908	64764,1781,148327,9230,8655,10540,5868,84516,6810,5869,5566,8766,10671,51164,51626,5878,1639	CREB3L2,DYNC1I2,CREB3L4,RAB11B,DYNLL1,DCTN2,RAB5A,DCTN5,STX4,RAB5B,PRKACA,RAB11A,DCTN6,DCTN4,DYNC2LI1,RAB5C,DCTN1
hsa04621	NOD-like receptor signaling pathway	0.0432949828160034	-3.13971852098733	57	21	0.0117647058823529	1785	6908	7184,330,7128,8767,7205,257397,3326,1147,2920,55914,329,10910,8517,22900,3569,5601,3551,3320,6885,5970,10454	HSP90B1,BIRC3,TNFAIP3,RIPK2,TRIP6,TAB3,HSP90AB1,CHUK,CXCL2,ERBB2IP,BIRC2,SUGT1,IKBKG,CARD8,IL6,MAPK9,IKBKB,HSP90AA1,MAP3K7,RELA,TAB1
ko04621	NOD-like receptor signaling pathway	0.0432949828160034	-3.13971852098733	57	21	0.0117647058823529	1785	6908	7184,330,7128,8767,7205,257397,3326,1147,2920,55914,329,10910,8517,22900,3569,5601,3551,3320,6885,5970,10454	HSP90B1,BIRC3,TNFAIP3,RIPK2,TRIP6,TAB3,HSP90AB1,CHUK,CXCL2,ERBB2IP,BIRC2,SUGT1,IKBKG,CARD8,IL6,MAPK9,IKBKB,HSP90AA1,MAP3K7,RELA,TAB1
hsa00100	Steroid biosynthesis	0.0494631529985603	-3.0065272704662	20	9	0.00504201680672269	1785	6908	6646,1595,6307,1718,1717,3988,6309,2222,10682	SOAT1,CYP51A1,MSMO1,DHCR24,DHCR7,LIPA,SC5D,FDFT1,EBP
ko00100	Steroid biosynthesis	0.0494631529985603	-3.0065272704662	20	9	0.00504201680672269	1785	6908	6646,1595,6307,1718,1717,3988,6309,10682,2222	SOAT1,CYP51A1,MSMO1,DHCR24,DHCR7,LIPA,SC5D,EBP,FDFT1
hsa03060	Protein export	0.0498949057293903	-2.99783637102754	23	10	0.00560224089635854	1785	6908	6726,6731,6734,23480,7095,3309,6729,60559,196294,6728	SRP9,SRP72,SRPR,SEC61G,SEC62,HSPA5,SRP54,SPCS3,IMMP1L,SRP19
ko03060	Protein export	0.0498949057293903	-2.99783637102754	23	10	0.00560224089635854	1785	6908	6726,6731,6734,23480,7095,3309,6729,60559,196294,6728	SRP9,SRP72,SRPR,SEC61G,SEC62,HSPA5,SRP54,SPCS3,IMMP1L,SRP19
hsa04114	Oocyte meiosis	0.0525660773458995	-2.94568428466548	112	37	0.0207282913165266	1785	6908	23291,51433,80315,9232,5604,22849,5526,7531,5566,26271,805,6196,5518,10393,51434,25847,991,10971,29882,8697,995,983,7532,817,5529,996,4085,8243,5500,5527,7534,151648,7533,9133,132864,5528,8945	FBXW11,ANAPC5,CPEB4,PTTG1,MAP2K1,CPEB3,PPP2R5B,YWHAE,PRKACA,FBXO5,CALM2,RPS6KA2,PPP2R1A,ANAPC10,ANAPC7,ANAPC13,CDC20,YWHAQ,ANAPC2,CDC23,CDC25C,CDK1,YWHAG,CAMK2D,PPP2R5E,CDC27,MAD2L1,SMC1A,PPP1CB,PPP2R5C,YWHAZ,SGOL1,YWHAH,CCNB2,CPEB2,PPP2R5D,BTRC
ko04114	Oocyte meiosis	0.0525660773458995	-2.94568428466548	112	37	0.0207282913165266	1785	6908	23291,51433,80315,9232,5604,22849,5526,7531,5566,26271,805,6196,5518,10393,51434,25847,991,10971,29882,8697,995,983,7532,817,5529,996,4085,8243,5500,5527,7534,151648,7533,9133,132864,5528,8945	FBXW11,ANAPC5,CPEB4,PTTG1,MAP2K1,CPEB3,PPP2R5B,YWHAE,PRKACA,FBXO5,CALM2,RPS6KA2,PPP2R1A,ANAPC10,ANAPC7,ANAPC13,CDC20,YWHAQ,ANAPC2,CDC23,CDC25C,CDK1,YWHAG,CAMK2D,PPP2R5E,CDC27,MAD2L1,SMC1A,PPP1CB,PPP2R5C,YWHAZ,SGOL1,YWHAH,CCNB2,CPEB2,PPP2R5D,BTRC
hsa05134	Legionellosis	0.0545160110242134	-2.90926084019711	55	20	0.0112044817927171	1785	6908	1195,842,3312,54205,2920,5861,23786,1915,7415,3304,51128,3592,840,56681,3569,81876,9554,4791,5970,10767	CLK1,CASP9,HSPA8,CYCS,CXCL2,RAB1A,BCL2L13,EEF1A1,VCP,HSPA1B,SAR1B,IL12A,CASP7,SAR1A,IL6,RAB1B,SEC22B,NFKB2,RELA,HBS1L
ko05134	Legionellosis	0.0545160110242134	-2.90926084019711	55	20	0.0112044817927171	1785	6908	1195,842,3312,54205,2920,5861,23786,1915,7415,3304,51128,3592,840,56681,3569,81876,9554,4791,5970,10767	CLK1,CASP9,HSPA8,CYCS,CXCL2,RAB1A,BCL2L13,EEF1A1,VCP,HSPA1B,SAR1B,IL12A,CASP7,SAR1A,IL6,RAB1B,SEC22B,NFKB2,RELA,HBS1L
ko00740	Riboflavin metabolism	0.0555841011600596	-2.88985806897584	4	3	0.00168067226890756	1785	6908	80308,55312,645	FLAD1,RFK,BLVRB
hsa00740	Riboflavin metabolism	0.0555841011600596	-2.88985806897584	4	3	0.00168067226890756	1785	6908	80308,55312,645	FLAD1,RFK,BLVRB
hsa05215	Prostate cancer	0.0593131111503284	-2.8249248987607	89	30	0.0168067226890756	1785	6908	64764,5170,148327,468,673,7184,2475,3326,5894,208,842,5604,7157,1871,3845,1147,6934,572,595,8517,369,1499,3551,5296,8503,2932,1027,3320,1870,5970	CREB3L2,PDPK1,CREB3L4,ATF4,BRAF,HSP90B1,MTOR,HSP90AB1,RAF1,AKT2,CASP9,MAP2K1,TP53,E2F3,KRAS,CHUK,TCF7L2,BAD,CCND1,IKBKG,ARAF,CTNNB1,IKBKB,PIK3R2,PIK3R3,GSK3B,CDKN1B,HSP90AA1,E2F2,RELA
ko05215	Prostate cancer	0.0593131111503284	-2.8249248987607	89	30	0.0168067226890756	1785	6908	64764,5170,148327,468,673,7184,2475,3326,5894,208,842,5604,7157,1871,3845,1147,6934,572,595,8517,369,1499,3551,5296,8503,2932,1027,3320,1870,5970	CREB3L2,PDPK1,CREB3L4,ATF4,BRAF,HSP90B1,MTOR,HSP90AB1,RAF1,AKT2,CASP9,MAP2K1,TP53,E2F3,KRAS,CHUK,TCF7L2,BAD,CCND1,IKBKG,ARAF,CTNNB1,IKBKB,PIK3R2,PIK3R3,GSK3B,CDKN1B,HSP90AA1,E2F2,RELA
ko00330	Arginine and proline metabolism	0.0601515247939337	-2.81088848702517	49	18	0.0100840336134454	1785	6908	384,5625,51056,6303,262,112849,8659,65263,5033,4128,501,2805,29920,55748,5832,112483,224,6611	ARG2,PRODH,LAP3,SAT1,AMD1,L3HYPDH,ALDH4A1,PYCRL,P4HA1,MAOA,ALDH7A1,GOT1,PYCR2,CNDP2,ALDH18A1,SAT2,ALDH3A2,SMS
hsa00330	Arginine and proline metabolism	0.0601515247939337	-2.81088848702517	49	18	0.0100840336134454	1785	6908	384,5625,51056,262,6303,112849,8659,65263,5033,4128,501,2805,29920,55748,5832,112483,224,6611	ARG2,PRODH,LAP3,AMD1,SAT1,L3HYPDH,ALDH4A1,PYCRL,P4HA1,MAOA,ALDH7A1,GOT1,PYCR2,CNDP2,ALDH18A1,SAT2,ALDH3A2,SMS
hsa04068	FoxO signaling pathway	0.060598267013249	-2.80348898345688	134	43	0.0240896358543417	1785	6908	1030,5564,6517,673,5565,5894,5562,5604,3276,1147,595,9456,11337,3551,5296,5601,23678,5105,10733,604,1027,6446,8503,1032,6774,901,23411,1263,5170,208,1454,6502,5571,9140,3845,92579,23710,51422,369,3569,10769,4616,9133	CDKN2B,PRKAB1,SLC2A4,BRAF,PRKAB2,RAF1,PRKAA1,MAP2K1,PRMT1,CHUK,CCND1,HOMER1,GABARAP,IKBKB,PIK3R2,MAPK9,SGK3,PCK1,PLK4,BCL6,CDKN1B,SGK1,PIK3R3,CDKN2D,STAT3,CCNG2,SIRT1,PLK3,PDPK1,AKT2,CSNK1E,SKP2,PRKAG1,ATG12,KRAS,G6PC3,GABARAPL1,PRKAG2,ARAF,IL6,PLK2,GADD45B,CCNB2
hsa05223	Non-small cell lung cancer	0.0649178841354715	-2.73463212874193	56	20	0.0112044817927171	1785	6908	5170,5915,673,1019,5894,208,842,5604,7157,1871,3845,6257,572,595,369,5296,8503,1870,1021,1029	PDPK1,RARB,BRAF,CDK4,RAF1,AKT2,CASP9,MAP2K1,TP53,E2F3,KRAS,RXRB,BAD,CCND1,ARAF,PIK3R2,PIK3R3,E2F2,CDK6,CDKN2A
ko05223	Non-small cell lung cancer	0.0649178841354715	-2.73463212874193	56	20	0.0112044817927171	1785	6908	5170,5915,673,1019,5894,208,842,5604,7157,1871,3845,6257,572,595,369,5296,8503,1870,1021,1029	PDPK1,RARB,BRAF,CDK4,RAF1,AKT2,CASP9,MAP2K1,TP53,E2F3,KRAS,RXRB,BAD,CCND1,ARAF,PIK3R2,PIK3R3,E2F2,CDK6,CDKN2A
hsa04012	ErbB signaling pathway	0.071583997191509	-2.63688373290792	87	29	0.0162464985994398	1785	6908	5058,673,5609,2475,4690,5894,208,5604,868,3845,6777,2002,27,572,3725,1399,817,369,6464,4609,5296,5601,8503,2932,1027,6198,145957,2065,6199	PAK1,BRAF,MAP2K7,MTOR,NCK1,RAF1,AKT2,MAP2K1,CBLB,KRAS,STAT5B,ELK1,ABL2,BAD,JUN,CRKL,CAMK2D,ARAF,SHC1,MYC,PIK3R2,MAPK9,PIK3R3,GSK3B,CDKN1B,RPS6KB1,NRG4,ERBB3,RPS6KB2
ko04012	ErbB signaling pathway	0.071583997191509	-2.63688373290792	87	29	0.0162464985994398	1785	6908	5058,673,5609,2475,4690,5894,208,5604,868,3845,6777,2002,1399,27,572,3725,817,6464,369,4609,5296,5601,1027,8503,2932,145957,6198,2065,6199	PAK1,BRAF,MAP2K7,MTOR,NCK1,RAF1,AKT2,MAP2K1,CBLB,KRAS,STAT5B,ELK1,CRKL,ABL2,BAD,JUN,CAMK2D,SHC1,ARAF,MYC,PIK3R2,MAPK9,CDKN1B,PIK3R3,GSK3B,NRG4,RPS6KB1,ERBB3,RPS6KB2
hsa04150	mTOR signaling pathway	0.0725256189654262	-2.62381541449987	60	21	0.0117647058823529	1785	6908	5170,673,1975,2475,208,5562,84335,6009,54541,7248,6196,3551,5296,6194,8503,6198,253260,81617,1977,6199,64223	PDPK1,BRAF,EIF4B,MTOR,AKT2,PRKAA1,AKT1S1,RHEB,DDIT4,TSC1,RPS6KA2,IKBKB,PIK3R2,RPS6,PIK3R3,RPS6KB1,RICTOR,CAB39L,EIF4E,RPS6KB2,MLST8
ko04150	mTOR signaling pathway	0.0725256189654262	-2.62381541449987	60	21	0.0117647058823529	1785	6908	5170,673,1975,2475,208,5562,84335,6009,54541,7248,6196,3551,5296,6194,8503,6198,253260,81617,1977,6199,64223	PDPK1,BRAF,EIF4B,MTOR,AKT2,PRKAA1,AKT1S1,RHEB,DDIT4,TSC1,RPS6KA2,IKBKB,PIK3R2,RPS6,PIK3R3,RPS6KB1,RICTOR,CAB39L,EIF4E,RPS6KB2,MLST8
ko04144	Endocytosis	0.0784816147429033	-2.54489088872131	258	77	0.0431372549019608	1785	6908	27243,9230,2870,8729,9815,8027,8411,30011,55737,9765,9727,4218,23527,998,10193,1785,118813,163,4233,147179,6642,116988,57132,10617,7879,3312,868,9525,5868,857,25978,5869,29934,10890,64145,8976,9798,1213,7251,9266,382,1175,27131,51019,3133,51534,3134,11311,11267,29924,23327,8766,7037,9559,4734,3105,5584,829,2065,3107,93343,2060,55616,9101,154,51652,8394,10552,64744,3304,160,79720,116985,138429,10109,5878,51699	CHMP2A,RAB11B,GRK6,GBF1,GIT2,STAM,EEA1,SH3KBP1,VPS35,ZFYVE16,RAB11FIP3,RAB8A,ACAP2,CDC42,RNF41,DNM2,ZFYVE27,AP2B1,MET,WIPF2,SNX1,AGAP3,CHMP1B,STAMBP,RAB7A,HSPA8,CBLB,VPS4B,RAB5A,CAV1,CHMP2B,RAB5B,SNX12,RAB10,RBSN,WASL,IST1,CLTC,TSG101,CYTH2,ARF6,AP2S1,SNX5,CCDC53,HLA-E,VTA1,HLA-F,VPS45,SNF8,EPN1,NEDD4L,RAB11A,TFRC,VPS26A,NEDD4,HLA-A,PRKCI,CAPZA1,ERBB3,HLA-C,MVB12A,EPS15,ASAP3,USP8,ADRB2,CHMP3,PIP5K1A,ARPC1A,SMAP2,HSPA1B,AP2A1,VPS37B,ARAP1,PIP5KL1,ARPC2,RAB5C,VPS29
hsa04144	Endocytosis	0.0784816147429033	-2.54489088872131	258	77	0.0431372549019608	1785	6908	27243,9230,2870,8729,9815,8027,8411,30011,55737,9765,9727,4218,23527,998,10193,1785,118813,163,4233,147179,6642,116988,57132,10617,7879,3312,868,9525,5868,857,25978,5869,29934,10890,64145,8976,9798,1213,7251,9266,382,1175,27131,51019,3133,51534,3134,11311,11267,29924,23327,8766,7037,9559,4734,3105,5584,829,2065,3107,93343,2060,55616,9101,154,51652,8394,10552,64744,3304,160,79720,116985,138429,10109,5878,51699	CHMP2A,RAB11B,GRK6,GBF1,GIT2,STAM,EEA1,SH3KBP1,VPS35,ZFYVE16,RAB11FIP3,RAB8A,ACAP2,CDC42,RNF41,DNM2,ZFYVE27,AP2B1,MET,WIPF2,SNX1,AGAP3,CHMP1B,STAMBP,RAB7A,HSPA8,CBLB,VPS4B,RAB5A,CAV1,CHMP2B,RAB5B,SNX12,RAB10,RBSN,WASL,IST1,CLTC,TSG101,CYTH2,ARF6,AP2S1,SNX5,CCDC53,HLA-E,VTA1,HLA-F,VPS45,SNF8,EPN1,NEDD4L,RAB11A,TFRC,VPS26A,NEDD4,HLA-A,PRKCI,CAPZA1,ERBB3,HLA-C,MVB12A,EPS15,ASAP3,USP8,ADRB2,CHMP3,PIP5K1A,ARPC1A,SMAP2,HSPA1B,AP2A1,VPS37B,ARAP1,PIP5KL1,ARPC2,RAB5C,VPS29
ko05219	Bladder cancer	0.084340926197011	-2.47288804901889	41	15	0.00840336134453781	1785	6908	595,1890,673,369,1019,5894,4609,5604,7157,1871,3845,1870,9252,1613,1029	CCND1,TYMP,BRAF,ARAF,CDK4,RAF1,MYC,MAP2K1,TP53,E2F3,KRAS,E2F2,RPS6KA5,DAPK3,CDKN2A
hsa05219	Bladder cancer	0.084340926197011	-2.47288804901889	41	15	0.00840336134453781	1785	6908	595,1890,673,369,1019,5894,4609,5604,7157,1871,3845,1870,9252,1613,1029	CCND1,TYMP,BRAF,ARAF,CDK4,RAF1,MYC,MAP2K1,TP53,E2F3,KRAS,E2F2,RPS6KA5,DAPK3,CDKN2A
ko04668	TNF signaling pathway	0.0929592913263902	-2.37559360933283	110	35	0.0196078431372549	1785	6908	64764,1388,257397,7186,5604,1147,2920,9252,329,5606,3725,3551,5296,5601,3726,8503,6885,1386,5970,468,148327,5609,330,7128,208,1906,2353,8772,5743,8517,840,5608,3569,4217,10454	CREB3L2,ATF6B,TAB3,TRAF2,MAP2K1,CHUK,CXCL2,RPS6KA5,BIRC2,MAP2K3,JUN,IKBKB,PIK3R2,MAPK9,JUNB,PIK3R3,MAP3K7,ATF2,RELA,ATF4,CREB3L4,MAP2K7,BIRC3,TNFAIP3,AKT2,EDN1,FOS,FADD,PTGS2,IKBKG,CASP7,MAP2K6,IL6,MAP3K5,TAB1
hsa04668	TNF signaling pathway	0.0929592913263902	-2.37559360933283	110	35	0.0196078431372549	1785	6908	64764,1388,257397,7186,5604,1147,2920,9252,329,5606,3725,3551,5296,5601,3726,8503,6885,1386,5970,468,148327,5609,330,7128,208,1906,2353,8772,5743,8517,840,5608,3569,4217,10454	CREB3L2,ATF6B,TAB3,TRAF2,MAP2K1,CHUK,CXCL2,RPS6KA5,BIRC2,MAP2K3,JUN,IKBKB,PIK3R2,MAPK9,JUNB,PIK3R3,MAP3K7,ATF2,RELA,ATF4,CREB3L4,MAP2K7,BIRC3,TNFAIP3,AKT2,EDN1,FOS,FADD,PTGS2,IKBKG,CASP7,MAP2K6,IL6,MAP3K5,TAB1
ko00230	Purine metabolism	0.094505188702411	-2.35910053908595	174	53	0.0296918767507003	1785	6908	23649,204,5440,171568,25885,6240,5424,51728,661,2618,5147,10606,4831,30833,11164,5144,55703,57804,64425,5631,5431,10621,2987,10201,5141,5471,5422,6241,8654,5151,221264,3615,27115,10714,4832,58497,5430,11128,221830,5432,159,131870,51292,654364,5198,29922,51082,5150,5434,3614,1716,87178,5425	POLA2,AK2,POLR2K,POLR3H,POLR1A,RRM1,POLD1,POLR3K,POLR3D,GART,PDE6D,PAICS,NME2,NT5C,NUDT5,PDE4D,POLR3B,POLD4,POLR1E,PRPS1,POLR2B,POLR3F,GUK1,NME6,PDE4A,PPAT,POLA1,RRM2,PDE5A,PDE8A,AK9,IMPDH2,PDE7B,POLD3,NME3,PRUNE,POLR2A,POLR3A,TWISTNB,POLR2C,ADSS,NUDT16,GMPR2,NME1-NME2,PFAS,NME7,POLR1D,PDE7A,POLR2E,IMPDH1,DGUOK,PNPT1,POLD2
hsa00230	Purine metabolism	0.094505188702411	-2.35910053908595	174	53	0.0296918767507003	1785	6908	23649,204,5440,25885,171568,6240,5424,51728,661,2618,5147,10606,4831,30833,11164,55703,5144,57804,64425,5631,5431,10621,5141,10201,2987,5471,5422,8654,6241,5151,3615,221264,27115,10714,4832,58497,11128,221830,5430,159,5432,131870,51292,654364,29922,5198,51082,5434,5150,3614,1716,87178,5425	POLA2,AK2,POLR2K,POLR1A,POLR3H,RRM1,POLD1,POLR3K,POLR3D,GART,PDE6D,PAICS,NME2,NT5C,NUDT5,POLR3B,PDE4D,POLD4,POLR1E,PRPS1,POLR2B,POLR3F,PDE4A,NME6,GUK1,PPAT,POLA1,PDE5A,RRM2,PDE8A,IMPDH2,AK9,PDE7B,POLD3,NME3,PRUNE,POLR3A,TWISTNB,POLR2A,ADSS,POLR2C,NUDT16,GMPR2,NME1-NME2,NME7,PFAS,POLR1D,POLR2E,PDE7A,IMPDH1,DGUOK,PNPT1,POLD2
ko00051	Fructose and mannose metabolism	0.0983881384738354	-2.31883502615502	32	12	0.00672268907563025	1785	6908	5372,4351,197258,57103,5208,6652,226,231,5209,29925,5373,29926	PMM1,MPI,FUK,TIGAR,PFKFB2,SORD,ALDOA,AKR1B1,PFKFB3,GMPPB,PMM2,GMPPA
hsa00051	Fructose and mannose metabolism	0.0983881384738354	-2.31883502615502	32	12	0.00672268907563025	1785	6908	5372,4351,197258,57103,5208,6652,226,29925,5209,231,5373,29926	PMM1,MPI,FUK,TIGAR,PFKFB2,SORD,ALDOA,GMPPB,PFKFB3,AKR1B1,PMM2,GMPPA
ko05216	Thyroid cancer	0.103414461354668	-2.26901046832472	29	11	0.0061624649859944	1785	6908	595,673,7170,1499,4609,5604,7157,3845,10342,6934,6257	CCND1,BRAF,TPM3,CTNNB1,MYC,MAP2K1,TP53,KRAS,TFG,TCF7L2,RXRB
hsa05216	Thyroid cancer	0.103414461354668	-2.26901046832472	29	11	0.0061624649859944	1785	6908	595,673,7170,1499,4609,5604,7157,3845,10342,6934,6257	CCND1,BRAF,TPM3,CTNNB1,MYC,MAP2K1,TP53,KRAS,TFG,TCF7L2,RXRB
hsa04142	Lysosome	0.118474138917115	-2.13306057921048	123	38	0.0212885154061625	1785	6908	9374,6272,967,26088,8943,427,162,4074,1200,20,8907,3373,23545,51606,9741,9114,175,2760,3920,2990,6609,2629,1777,535,4891,26503,9179,138050,3988,4864,4758,968,1497,23659,1213,55353,1201,164	PPT2,SORT1,CD63,GGA1,AP3D1,ASAH1,AP1B1,M6PR,TPP1,ABCA2,AP1M1,HYAL1,ATP6V0A2,ATP6V1H,LAPTM4A,ATP6V0D1,AGA,GM2A,LAMP2,GUSB,SMPD1,GBA,DNASE2,ATP6V0A1,SLC11A2,SLC17A5,AP4M1,HGSNAT,LIPA,NPC1,NEU1,CD68,CTNS,PLA2G15,CLTC,LAPTM4B,CLN3,AP1G1
ko04142	Lysosome	0.118474138917115	-2.13306057921048	123	38	0.0212885154061625	1785	6908	9374,6272,967,26088,8943,427,162,4074,1200,20,8907,3373,23545,51606,9741,9114,175,2760,3920,2990,6609,2629,1777,535,4891,26503,9179,138050,3988,4864,4758,968,1497,23659,1213,55353,1201,164	PPT2,SORT1,CD63,GGA1,AP3D1,ASAH1,AP1B1,M6PR,TPP1,ABCA2,AP1M1,HYAL1,ATP6V0A2,ATP6V1H,LAPTM4A,ATP6V0D1,AGA,GM2A,LAMP2,GUSB,SMPD1,GBA,DNASE2,ATP6V0A1,SLC11A2,SLC17A5,AP4M1,HGSNAT,LIPA,NPC1,NEU1,CD68,CTNS,PLA2G15,CLTC,LAPTM4B,CLN3,AP1G1
ko04260	Cardiac muscle contraction	0.122425207931422	-2.10025498295598	74	24	0.0134453781512605	1785	6908	1350,7169,7170,7381,27089,7171,1347,7386,59283,476,488,1337,783,9167,1351,7385,9377,6548,7388,1349,784,1537,483,1340	COX7C,TPM2,TPM3,UQCRB,UQCRQ,TPM4,COX7A2,UQCRFS1,CACNG8,ATP1A1,ATP2A2,COX6A1,CACNB2,COX7A2L,COX8A,UQCRC2,COX5A,SLC9A1,UQCRH,COX7B,CACNB3,CYC1,ATP1B3,COX6B1
hsa04260	Cardiac muscle contraction	0.122425207931422	-2.10025498295598	74	24	0.0134453781512605	1785	6908	1350,7169,7170,7381,27089,7171,1347,7386,59283,476,488,1337,783,9167,1351,7385,9377,6548,7388,1349,784,1537,483,1340	COX7C,TPM2,TPM3,UQCRB,UQCRQ,TPM4,COX7A2,UQCRFS1,CACNG8,ATP1A1,ATP2A2,COX6A1,CACNB2,COX7A2L,COX8A,UQCRC2,COX5A,SLC9A1,UQCRH,COX7B,CACNB3,CYC1,ATP1B3,COX6B1
hsa00450	Selenocompound metabolism	0.123223424112566	-2.09375611517147	17	7	0.00392156862745098	1785	6908	7296,56267,883,51091,4548,1491,51540	TXNRD1,CCBL2,CCBL1,SEPSECS,MTR,CTH,SCLY
ko00450	Selenocompound metabolism	0.123223424112566	-2.09375611517147	17	7	0.00392156862745098	1785	6908	7296,56267,883,51091,4548,1491,51540	TXNRD1,CCBL2,CCBL1,SEPSECS,MTR,CTH,SCLY
ko04722	Neurotrophin signaling pathway	0.124884165051887	-2.08036865089771	120	37	0.0207282913165266	1785	6908	6272,673,5607,5894,5604,7157,7531,9252,5663,805,3725,1399,6196,998,6464,3551,5296,5601,581,5781,8503,5598,5970,4215,5170,627,468,8767,5609,208,3845,572,817,27018,25970,2932,4217	SORT1,BRAF,MAP2K5,RAF1,MAP2K1,TP53,YWHAE,RPS6KA5,PSEN1,CALM2,JUN,CRKL,RPS6KA2,CDC42,SHC1,IKBKB,PIK3R2,MAPK9,BAX,PTPN11,PIK3R3,MAPK7,RELA,MAP3K3,PDPK1,BDNF,ATF4,RIPK2,MAP2K7,AKT2,KRAS,BAD,CAMK2D,NGFRAP1,SH2B1,GSK3B,MAP3K5
hsa04722	Neurotrophin signaling pathway	0.124884165051887	-2.08036865089771	120	37	0.0207282913165266	1785	6908	6272,673,5607,5894,5604,7157,7531,9252,5663,805,3725,1399,6196,998,6464,3551,5296,5601,581,5781,8503,5598,5970,4215,5170,627,468,8767,5609,208,3845,572,817,27018,25970,2932,4217	SORT1,BRAF,MAP2K5,RAF1,MAP2K1,TP53,YWHAE,RPS6KA5,PSEN1,CALM2,JUN,CRKL,RPS6KA2,CDC42,SHC1,IKBKB,PIK3R2,MAPK9,BAX,PTPN11,PIK3R3,MAPK7,RELA,MAP3K3,PDPK1,BDNF,ATF4,RIPK2,MAP2K7,AKT2,KRAS,BAD,CAMK2D,NGFRAP1,SH2B1,GSK3B,MAP3K5
hsa05100	Bacterial invasion of epithelial cells	0.130104689707378	-2.03941584716963	78	25	0.0140056022408964	1785	6908	10163,2335,8936,10801,1495,868,857,4735,10552,1399,6464,1499,23607,998,63916,8976,1213,5296,3688,1785,8503,2017,4233,10109,7414	WASF2,FN1,WASF1,SEPT9,CTNNA1,CBLB,CAV1,SEPT2,ARPC1A,CRKL,SHC1,CTNNB1,CD2AP,CDC42,ELMO2,WASL,CLTC,PIK3R2,ITGB1,DNM2,PIK3R3,CTTN,MET,ARPC2,VCL
ko05100	Bacterial invasion of epithelial cells	0.130104689707378	-2.03941584716963	78	25	0.0140056022408964	1785	6908	10163,2335,8936,10801,1495,868,857,4735,10552,1399,6464,1499,23607,998,63916,8976,1213,5296,3688,1785,8503,2017,4233,10109,7414	WASF2,FN1,WASF1,SEPT9,CTNNA1,CBLB,CAV1,SEPT2,ARPC1A,CRKL,SHC1,CTNNB1,CD2AP,CDC42,ELMO2,WASL,CLTC,PIK3R2,ITGB1,DNM2,PIK3R3,CTTN,MET,ARPC2,VCL
hsa00270	Cysteine and methionine metabolism	0.135126213515368	-2.00154602237582	37	13	0.00728291316526611	1785	6908	58478,27430,4191,262,84245,3939,2805,10768,4548,4507,23382,1491,6611	ENOPH1,MAT2B,MDH2,AMD1,MRI1,LDHA,GOT1,AHCYL1,MTR,MTAP,AHCYL2,CTH,SMS
ko00270	Cysteine and methionine metabolism	0.135126213515368	-2.00154602237582	37	13	0.00728291316526611	1785	6908	58478,27430,4191,262,84245,3939,2805,10768,4548,4507,23382,1491,6611	ENOPH1,MAT2B,MDH2,AMD1,MRI1,LDHA,GOT1,AHCYL1,MTR,MTAP,AHCYL2,CTH,SMS
hsa04919	Thyroid hormone signaling pathway	0.144339841424471	-1.93558474996359	118	36	0.0201680672268908	1785	6908	2475,5894,1734,5604,7157,1827,25942,5566,29079,595,488,1499,4609,5296,6548,9862,8503,90390,5170,5208,208,842,9442,3845,10025,6009,6257,572,8202,476,6772,2932,9282,483,9882,3066	MTOR,RAF1,DIO2,MAP2K1,TP53,RCAN1,SIN3A,PRKACA,MED4,CCND1,ATP2A2,CTNNB1,MYC,PIK3R2,SLC9A1,MED24,PIK3R3,MED30,PDPK1,PFKFB2,AKT2,CASP9,MED27,KRAS,MED16,RHEB,RXRB,BAD,NCOA3,ATP1A1,STAT1,GSK3B,MED14,ATP1B3,TBC1D4,HDAC2
hsa05145	Toxoplasmosis	0.144339841424471	-1.93558474996359	118	36	0.0201680672268908	1785	6908	3122,1147,54205,598,329,5606,3914,3592,8651,3551,5296,5601,8503,3717,6885,3459,2771,5970,6774,5170,330,208,3312,842,3109,2773,7297,3587,3304,572,3108,8517,5608,3688,6772,10454	HLA-DRA,CHUK,CYCS,BCL2L1,BIRC2,MAP2K3,LAMB3,IL12A,SOCS1,IKBKB,PIK3R2,MAPK9,PIK3R3,JAK2,MAP3K7,IFNGR1,GNAI2,RELA,STAT3,PDPK1,BIRC3,AKT2,HSPA8,CASP9,HLA-DMB,GNAI3,TYK2,IL10RA,HSPA1B,BAD,HLA-DMA,IKBKG,MAP2K6,ITGB1,STAT1,TAB1
ko05145	Toxoplasmosis	0.144339841424471	-1.93558474996359	118	36	0.0201680672268908	1785	6908	3122,1147,54205,598,329,5606,3914,3592,8651,3551,5296,5601,8503,3717,6885,3459,2771,5970,6774,5170,330,208,3312,842,3109,2773,7297,3587,3304,572,3108,8517,5608,3688,6772,10454	HLA-DRA,CHUK,CYCS,BCL2L1,BIRC2,MAP2K3,LAMB3,IL12A,SOCS1,IKBKB,PIK3R2,MAPK9,PIK3R3,JAK2,MAP3K7,IFNGR1,GNAI2,RELA,STAT3,PDPK1,BIRC3,AKT2,HSPA8,CASP9,HLA-DMB,GNAI3,TYK2,IL10RA,HSPA1B,BAD,HLA-DMA,IKBKG,MAP2K6,ITGB1,STAT1,TAB1
hsa01230	Biosynthesis of amino acids	0.163753964552523	-1.80939019375209	73	23	0.0128851540616246	1785	6908	384,6470,1373,2597,29968,4548,27430,50,5091,5230,65263,226,1431,2805,5224,501,29920,3420,5832,5631,5723,22934,1491	ARG2,SHMT1,CPS1,GAPDH,PSAT1,MTR,MAT2B,ACO2,PC,PGK1,PYCRL,ALDOA,CS,GOT1,PGAM2,ALDH7A1,PYCR2,IDH3B,ALDH18A1,PRPS1,PSPH,RPIA,CTH
ko01230	Biosynthesis of amino acids	0.163753964552523	-1.80939019375209	73	23	0.0128851540616246	1785	6908	384,6470,1373,2597,29968,4548,27430,50,5091,5230,65263,226,1431,2805,5224,501,29920,3420,5832,5631,5723,22934,1491	ARG2,SHMT1,CPS1,GAPDH,PSAT1,MTR,MAT2B,ACO2,PC,PGK1,PYCRL,ALDOA,CS,GOT1,PGAM2,ALDH7A1,PYCR2,IDH3B,ALDH18A1,PRPS1,PSPH,RPIA,CTH
ko05211	Renal cell carcinoma	0.164681657736572	-1.80374101572004	66	21	0.0117647058823529	1785	6908	5058,673,5894,208,5604,2271,3845,6921,3725,1399,112398,998,369,201163,8453,5296,5781,8503,4233,112399,405	PAK1,BRAF,RAF1,AKT2,MAP2K1,FH,KRAS,TCEB1,JUN,CRKL,EGLN2,CDC42,ARAF,FLCN,CUL2,PIK3R2,PTPN11,PIK3R3,MET,EGLN3,ARNT
hsa05211	Renal cell carcinoma	0.164681657736572	-1.80374101572004	66	21	0.0117647058823529	1785	6908	5058,673,5894,208,5604,2271,3845,6921,3725,1399,112398,998,369,201163,8453,5296,5781,8503,4233,112399,405	PAK1,BRAF,RAF1,AKT2,MAP2K1,FH,KRAS,TCEB1,JUN,CRKL,EGLN2,CDC42,ARAF,FLCN,CUL2,PIK3R2,PTPN11,PIK3R3,MET,EGLN3,ARNT
hsa00780	Biotin metabolism	0.165759901345145	-1.79721491507803	3	2	0.00112044817927171	1785	6908	54995,686	OXSM,BTD
ko00780	Biotin metabolism	0.165759901345145	-1.79721491507803	3	2	0.00112044817927171	1785	6908	54995,686	OXSM,BTD
ko04920	Adipocytokine signaling pathway	0.173726654306209	-1.75027216727012	70	22	0.0123249299719888	1785	6908	5564,6517,2475,7186,208,5565,5562,79602,5571,1147,92579,6257,8517,51422,3551,5601,5781,5105,3717,10891,6774,5970	PRKAB1,SLC2A4,MTOR,TRAF2,AKT2,PRKAB2,PRKAA1,ADIPOR2,PRKAG1,CHUK,G6PC3,RXRB,IKBKG,PRKAG2,IKBKB,MAPK9,PTPN11,PCK1,JAK2,PPARGC1A,STAT3,RELA
hsa04920	Adipocytokine signaling pathway	0.173726654306209	-1.75027216727012	70	22	0.0123249299719888	1785	6908	5564,6517,2475,7186,208,5565,5562,79602,5571,1147,92579,6257,8517,51422,3551,5601,5781,5105,3717,10891,6774,5970	PRKAB1,SLC2A4,MTOR,TRAF2,AKT2,PRKAB2,PRKAA1,ADIPOR2,PRKAG1,CHUK,G6PC3,RXRB,IKBKG,PRKAG2,IKBKB,MAPK9,PTPN11,PCK1,JAK2,PPARGC1A,STAT3,RELA
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	0.205296968500248	-1.58329772126087	68	21	0.0117647058823529	1785	6908	5058,6868,523,535,50848,7082,1147,3725,8517,51382,998,3551,5601,5781,23545,528,4233,51606,5970,529,9114	PAK1,ADAM17,ATP6V1A,ATP6V0A1,F11R,TJP1,CHUK,JUN,IKBKG,ATP6V1D,CDC42,IKBKB,MAPK9,PTPN11,ATP6V0A2,ATP6V1C1,MET,ATP6V1H,RELA,ATP6V1E1,ATP6V0D1
ko05120	Epithelial cell signaling in Helicobacter pylori infection	0.205296968500248	-1.58329772126087	68	21	0.0117647058823529	1785	6908	5058,6868,523,535,50848,7082,1147,3725,8517,51382,998,3551,5601,5781,23545,528,4233,51606,5970,529,9114	PAK1,ADAM17,ATP6V1A,ATP6V0A1,F11R,TJP1,CHUK,JUN,IKBKG,ATP6V1D,CDC42,IKBKB,MAPK9,PTPN11,ATP6V0A2,ATP6V1C1,MET,ATP6V1H,RELA,ATP6V1E1,ATP6V0D1
hsa04917	Prolactin signaling pathway	0.21423677470705	-1.54067345173134	72	22	0.0123249299719888	1785	6908	1081,208,5894,5604,3845,6777,2100,2353,30837,595,6464,8651,5601,5296,6772,122809,8503,2932,3717,5970,6774,9655	CGA,AKT2,RAF1,MAP2K1,KRAS,STAT5B,ESR2,FOS,SOCS7,CCND1,SHC1,SOCS1,MAPK9,PIK3R2,STAT1,SOCS4,PIK3R3,GSK3B,JAK2,RELA,STAT3,SOCS5
ko04917	Prolactin signaling pathway	0.21423677470705	-1.54067345173134	72	22	0.0123249299719888	1785	6908	1081,208,5894,5604,3845,6777,2100,2353,30837,595,6464,8651,5601,5296,6772,122809,8503,2932,3717,5970,6774,9655	CGA,AKT2,RAF1,MAP2K1,KRAS,STAT5B,ESR2,FOS,SOCS7,CCND1,SHC1,SOCS1,MAPK9,PIK3R2,STAT1,SOCS4,PIK3R3,GSK3B,JAK2,RELA,STAT3,SOCS5
ko04922	Glucagon signaling pathway	0.215933855096902	-1.53278314459808	101	30	0.0168067226890756	1785	6908	64764,23411,5160,5564,148327,468,5837,208,5565,5562,5531,5257,3276,3939,5571,92579,5566,200186,805,817,51422,57223,5105,2997,5224,55671,5256,10891,1386,5261	CREB3L2,SIRT1,PDHA1,PRKAB1,CREB3L4,ATF4,PYGM,AKT2,PRKAB2,PRKAA1,PPP4C,PHKB,PRMT1,LDHA,PRKAG1,G6PC3,PRKACA,CRTC2,CALM2,CAMK2D,PRKAG2,PPP4R3B,PCK1,GYS1,PGAM2,PPP4R3A,PHKA2,PPARGC1A,ATF2,PHKG2
hsa04922	Glucagon signaling pathway	0.215933855096902	-1.53278314459808	101	30	0.0168067226890756	1785	6908	64764,23411,5160,5564,148327,468,5837,208,5565,5562,5531,5257,3276,3939,5571,92579,5566,200186,805,817,51422,57223,5105,2997,5224,55671,5256,10891,1386,5261	CREB3L2,SIRT1,PDHA1,PRKAB1,CREB3L4,ATF4,PYGM,AKT2,PRKAB2,PRKAA1,PPP4C,PHKB,PRMT1,LDHA,PRKAG1,G6PC3,PRKACA,CRTC2,CALM2,CAMK2D,PRKAG2,PPP4R3B,PCK1,GYS1,PGAM2,PPP4R3A,PHKA2,PPARGC1A,ATF2,PHKG2
ko05130	Pathogenic Escherichia coli infection	0.235867116727155	-1.44448669725244	55	17	0.00952380952380952	1785	6908	4690,10383,10971,4691,10552,1499,998,8976,3688,9181,7534,2017,10109,3875,9475,203068,10381	NCK1,TUBB4B,YWHAQ,NCL,ARPC1A,CTNNB1,CDC42,WASL,ITGB1,ARHGEF2,YWHAZ,CTTN,ARPC2,KRT18,ROCK2,TUBB,TUBB3
hsa05130	Pathogenic Escherichia coli infection	0.235867116727155	-1.44448669725244	55	17	0.00952380952380952	1785	6908	4690,10383,10971,4691,10552,1499,998,8976,3688,9181,7534,2017,10109,3875,9475,203068,10381	NCK1,TUBB4B,YWHAQ,NCL,ARPC1A,CTNNB1,CDC42,WASL,ITGB1,ARHGEF2,YWHAZ,CTTN,ARPC2,KRT18,ROCK2,TUBB,TUBB3
hsa04122	Sulfur relay system	0.243939395915051	-1.41083546193704	10	4	0.00224089635854342	1785	6908	27304,348180,90353,9054	MOCS3,CTU2,CTU1,NFS1
ko04122	Sulfur relay system	0.243939395915051	-1.41083546193704	10	4	0.00224089635854342	1785	6908	27304,348180,90353,9054	MOCS3,CTU2,CTU1,NFS1
hsa04066	HIF-1 signaling pathway	0.253262996437193	-1.37332681856322	103	30	0.0168067226890756	1785	6908	5160,2597,5163,2475,208,1906,5604,3939,5209,6921,7037,817,112398,5230,3569,8453,5296,226,6194,1027,8503,6198,112399,3459,1977,5970,6774,284,405,6199	PDHA1,GAPDH,PDK1,MTOR,AKT2,EDN1,MAP2K1,LDHA,PFKFB3,TCEB1,TFRC,CAMK2D,EGLN2,PGK1,IL6,CUL2,PIK3R2,ALDOA,RPS6,CDKN1B,PIK3R3,RPS6KB1,EGLN3,IFNGR1,EIF4E,RELA,STAT3,ANGPT1,ARNT,RPS6KB2
hsa00730	Thiamine metabolism	0.275935701532014	-1.28758740586937	4	2	0.00112044817927171	1785	6908	9054,27010	NFS1,TPK1
ko00730	Thiamine metabolism	0.275935701532014	-1.28758740586937	4	2	0.00112044817927171	1785	6908	9054,27010	NFS1,TPK1
ko00260	Glycine, serine and threonine metabolism	0.29373151696487	-1.22508913647403	39	12	0.00672268907563025	1785	6908	55349,6470,29968,23464,669,4128,501,5224,1738,2653,5723,1491	CHDH,SHMT1,PSAT1,GCAT,BPGM,MAOA,ALDH7A1,PGAM2,DLD,GCSH,PSPH,CTH
hsa00260	Glycine, serine and threonine metabolism	0.29373151696487	-1.22508913647403	39	12	0.00672268907563025	1785	6908	55349,6470,29968,669,23464,4128,5224,501,1738,2653,5723,1491	CHDH,SHMT1,PSAT1,BPGM,GCAT,MAOA,PGAM2,ALDH7A1,DLD,GCSH,PSPH,CTH
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	0.307285659032712	-1.1799774785796	25	8	0.00448179271708683	1785	6908	5279,51604,54872,128869,84720,5277,9487,5281	PIGC,PIGT,PIGG,PIGU,PIGO,PIGA,PIGL,PIGF
ko00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	0.307285659032712	-1.1799774785796	25	8	0.00448179271708683	1785	6908	5279,128869,51604,5277,84720,9487,5281,54872	PIGC,PIGU,PIGT,PIGA,PIGO,PIGL,PIGF,PIGG
hsa05214	Glioma	0.307836719533106	-1.17818576796391	65	19	0.0106442577030812	1785	6908	673,2475,1019,5894,208,5604,7157,1871,3845,805,595,817,6464,369,5296,8503,1870,1021,1029	BRAF,MTOR,CDK4,RAF1,AKT2,MAP2K1,TP53,E2F3,KRAS,CALM2,CCND1,CAMK2D,SHC1,ARAF,PIK3R2,PIK3R3,E2F2,CDK6,CDKN2A
ko05214	Glioma	0.307836719533106	-1.17818576796391	65	19	0.0106442577030812	1785	6908	673,2475,1019,5894,208,5604,7157,1871,3845,805,595,817,6464,369,5296,8503,1870,1021,1029	BRAF,MTOR,CDK4,RAF1,AKT2,MAP2K1,TP53,E2F3,KRAS,CALM2,CCND1,CAMK2D,SHC1,ARAF,PIK3R2,PIK3R3,E2F2,CDK6,CDKN2A
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.30997022469577	-1.17127903548446	11	4	0.00224089635854342	1785	6908	2677,84274,1728,51004	GGCX,COQ5,NQO1,COQ6
hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.30997022469577	-1.17127903548446	11	4	0.00224089635854342	1785	6908	2677,84274,1728,51004	GGCX,COQ5,NQO1,COQ6
hsa05416	Viral myocarditis	0.317665881064856	-1.14675513703733	58	17	0.00952380952380952	1785	6908	3122,27,3108,595,1604,3134,3133,842,3109,8672,54205,3107,857,1982,1605,3105,1525	HLA-DRA,ABL2,HLA-DMA,CCND1,CD55,HLA-F,HLA-E,CASP9,HLA-DMB,EIF4G3,CYCS,HLA-C,CAV1,EIF4G2,DAG1,HLA-A,CXADR
hsa00280	Valine, leucine and isoleucine degradation	0.317825742358172	-1.14625202640362	47	14	0.00784313725490196	1785	6908	3157,3033,4329,4594,593,594,3032,56922,501,1738,1629,224,64087,11112	HMGCS1,HADH,ALDH6A1,MUT,BCKDHA,BCKDHB,HADHB,MCCC1,ALDH7A1,DLD,DBT,ALDH3A2,MCCC2,HIBADH
ko00280	Valine, leucine and isoleucine degradation	0.317825742358172	-1.14625202640362	47	14	0.00784313725490196	1785	6908	3157,3033,4329,4594,593,594,3032,56922,501,1738,1629,224,64087,11112	HMGCS1,HADH,ALDH6A1,MUT,BCKDHA,BCKDHB,HADHB,MCCC1,ALDH7A1,DLD,DBT,ALDH3A2,MCCC2,HIBADH
ko00620	Pyruvate metabolism	0.328204004352913	-1.11411989944716	40	12	0.00672268907563025	1785	6908	5160,5091,97,4191,3939,5105,2271,501,2739,3029,1738,224	PDHA1,PC,ACYP1,MDH2,LDHA,PCK1,FH,ALDH7A1,GLO1,HAGH,DLD,ALDH3A2
hsa00620	Pyruvate metabolism	0.328204004352913	-1.11411989944716	40	12	0.00672268907563025	1785	6908	5160,5091,97,4191,5105,3939,2271,501,2739,3029,1738,224	PDHA1,PC,ACYP1,MDH2,PCK1,LDHA,FH,ALDH7A1,GLO1,HAGH,DLD,ALDH3A2
hsa05014	Amyotrophic lateral sclerosis (ALS)	0.328224035429748	-1.11405886891334	51	15	0.00840336134453781	1785	6908	79139,572,1616,5608,842,7157,581,84134,54205,5868,598,10452,4217,5606,57679	DERL1,BAD,DAXX,MAP2K6,CASP9,TP53,BAX,TOMM40L,CYCS,RAB5A,BCL2L1,TOMM40,MAP3K5,MAP2K3,ALS2
ko05014	Amyotrophic lateral sclerosis (ALS)	0.328224035429748	-1.11405886891334	51	15	0.00840336134453781	1785	6908	79139,572,1616,5608,842,7157,581,84134,54205,5868,598,10452,4217,5606,57679	DERL1,BAD,DAXX,MAP2K6,CASP9,TP53,BAX,TOMM40L,CYCS,RAB5A,BCL2L1,TOMM40,MAP3K5,MAP2K3,ALS2
ko04330	Notch signaling pathway	0.349984122640778	-1.04986748941114	48	14	0.00784313725490196	1785	6908	3280,9253,6868,51107,23220,9541,1488,3516,9794,5663,23385,3066,8650,1856	HES1,NUMBL,ADAM17,APH1A,DTX4,CIR1,CTBP2,RBPJ,MAML1,PSEN1,NCSTN,HDAC2,NUMB,DVL2
hsa04330	Notch signaling pathway	0.349984122640778	-1.04986748941114	48	14	0.00784313725490196	1785	6908	3280,9253,6868,51107,23220,9541,1488,3516,9794,5663,23385,3066,8650,1856	HES1,NUMBL,ADAM17,APH1A,DTX4,CIR1,CTBP2,RBPJ,MAML1,PSEN1,NCSTN,HDAC2,NUMB,DVL2
hsa00310	Lysine degradation	0.359378096219301	-1.02338025190089	52	15	0.00840336134453781	1785	6908	55870,84787,3033,387893,6419,55753,9757,79709,501,4967,8985,2639,4297,1743,224	ASH1L,KMT5C,HADH,KMT5A,SETMAR,OGDHL,KMT2B,COLGALT1,ALDH7A1,OGDH,PLOD3,GCDH,KMT2A,DLST,ALDH3A2
ko00310	Lysine degradation	0.359378096219301	-1.02338025190089	52	15	0.00840336134453781	1785	6908	55870,3033,84787,387893,6419,55753,9757,79709,501,4967,8985,2639,1743,4297,224	ASH1L,HADH,KMT5C,KMT5A,SETMAR,OGDHL,KMT2B,COLGALT1,ALDH7A1,OGDH,PLOD3,GCDH,DLST,KMT2A,ALDH3A2
ko05231	Choline metabolism in cancer	0.368101962282262	-0.999395307771214	101	28	0.0156862745098039	1785	6908	10163,5170,8936,2475,208,5894,8681,5604,5900,8527,3845,8394,2353,6009,1119,3725,7248,8976,5296,23446,5601,10434,8503,6198,6583,5130,6667,6199	WASF2,PDPK1,WASF1,MTOR,AKT2,RAF1,JMJD7-PLA2G4B,MAP2K1,RALGDS,DGKD,KRAS,PIP5K1A,FOS,RHEB,CHKA,JUN,TSC1,WASL,PIK3R2,SLC44A1,MAPK9,LYPLA1,PIK3R3,RPS6KB1,SLC22A4,PCYT1A,SP1,RPS6KB2
hsa05231	Choline metabolism in cancer	0.368101962282262	-0.999395307771214	101	28	0.0156862745098039	1785	6908	10163,5170,8936,2475,208,5894,8681,5604,5900,8527,3845,8394,2353,6009,1119,3725,7248,8976,5296,23446,5601,10434,8503,6198,6583,5130,6667,6199	WASF2,PDPK1,WASF1,MTOR,AKT2,RAF1,JMJD7-PLA2G4B,MAP2K1,RALGDS,DGKD,KRAS,PIP5K1A,FOS,RHEB,CHKA,JUN,TSC1,WASL,PIK3R2,SLC44A1,MAPK9,LYPLA1,PIK3R3,RPS6KB1,SLC22A4,PCYT1A,SP1,RPS6KB2
hsa05030	Cocaine addiction	0.382701289936249	-0.960500515936226	49	14	0.00784313725490196	1785	6908	64764,3725,627,148327,468,1388,2354,1742,4128,2771,2773,1386,5970,5566	CREB3L2,JUN,BDNF,CREB3L4,ATF4,ATF6B,FOSB,DLG4,MAOA,GNAI2,GNAI3,ATF2,RELA,PRKACA
ko05030	Cocaine addiction	0.382701289936249	-0.960500515936226	49	14	0.00784313725490196	1785	6908	64764,3725,627,148327,468,1388,2354,1742,4128,2771,2773,1386,5970,5566	CREB3L2,JUN,BDNF,CREB3L4,ATF4,ATF6B,FOSB,DLG4,MAOA,GNAI2,GNAI3,ATF2,RELA,PRKACA
ko01200	Carbon metabolism	0.383111053321669	-0.959430375377297	113	31	0.0173669467787115	1785	6908	5160,6470,1373,2597,4594,4329,29968,25796,8802,6391,4191,55753,2271,83440,4967,1743,5226,6392,50,283871,5091,5230,226,1431,2805,5224,3420,1738,5631,5723,22934	PDHA1,SHMT1,CPS1,GAPDH,MUT,ALDH6A1,PSAT1,PGLS,SUCLG1,SDHC,MDH2,OGDHL,FH,ADPGK,OGDH,DLST,PGD,SDHD,ACO2,PGP,PC,PGK1,ALDOA,CS,GOT1,PGAM2,IDH3B,DLD,PRPS1,PSPH,RPIA
hsa01200	Carbon metabolism	0.383111053321669	-0.959430375377297	113	31	0.0173669467787115	1785	6908	5160,6470,1373,2597,4594,4329,29968,25796,8802,6391,4191,55753,2271,83440,4967,1743,5226,6392,50,283871,5091,5230,226,1431,2805,5224,3420,1738,5631,5723,22934	PDHA1,SHMT1,CPS1,GAPDH,MUT,ALDH6A1,PSAT1,PGLS,SUCLG1,SDHC,MDH2,OGDHL,FH,ADPGK,OGDH,DLST,PGD,SDHD,ACO2,PGP,PC,PGK1,ALDOA,CS,GOT1,PGAM2,IDH3B,DLD,PRPS1,PSPH,RPIA
hsa05200	Pathways in cancer	0.407375871181507	-0.898019003301979	397	105	0.0588235294117647	1785	6908	2475,5894,10928,5604,7157,324,1147,6777,1488,598,2535,5566,329,2783,595,1399,998,1499,3551,4286,5296,8503,1027,4233,4791,112399,10342,5970,2787,1021,1856,1164,2735,8321,5914,330,7170,1019,3326,208,2788,842,5734,868,1871,2271,2773,572,5743,8517,675,112398,59345,6772,3688,2932,9618,1870,405,3066,1030,9170,7184,673,2335,3728,1495,7186,5900,54205,4292,3914,3725,80326,4609,5601,9138,4436,581,1163,51764,3320,6774,2771,9475,2956,5915,6502,23365,3845,6921,2323,2353,1613,6934,8772,6257,5467,2768,369,332,3569,8453,1288,1029	MTOR,RAF1,RALBP1,MAP2K1,TP53,APC,CHUK,STAT5B,CTBP2,BCL2L1,FZD2,PRKACA,BIRC2,GNB2,CCND1,CRKL,CDC42,CTNNB1,IKBKB,MITF,PIK3R2,PIK3R3,CDKN1B,MET,NFKB2,EGLN3,TFG,RELA,GNG5,CDK6,DVL2,CKS2,GLI1,FZD1,RARA,BIRC3,TPM3,CDK4,HSP90AB1,AKT2,GNG7,CASP9,PTGER4,CBLB,E2F3,FH,GNAI3,BAD,PTGS2,IKBKG,BRCA2,EGLN2,GNB4,STAT1,ITGB1,GSK3B,TRAF4,E2F2,ARNT,HDAC2,CDKN2B,LPAR2,HSP90B1,BRAF,FN1,JUP,CTNNA1,TRAF2,RALGDS,CYCS,MLH1,LAMB3,JUN,WNT10A,MYC,MAPK9,ARHGEF1,MSH2,BAX,CKS1B,GNG13,HSP90AA1,STAT3,GNAI2,ROCK2,MSH6,RARB,SKP2,ARHGEF12,KRAS,TCEB1,FLT3LG,FOS,DAPK3,TCF7L2,FADD,RXRB,PPARD,GNA12,ARAF,BIRC5,IL6,CUL2,COL4A6,CDKN2A
hsa00670	One carbon pool by folate	0.416925405091341	-0.874847957858151	20	6	0.00336134453781513	1785	6908	2618,200895,6470,10797,441024,4548	GART,DHFRL1,SHMT1,MTHFD2,MTHFD2L,MTR
ko00670	One carbon pool by folate	0.416925405091341	-0.874847957858151	20	6	0.00336134453781513	1785	6908	6470,2618,10797,200895,441024,4548	SHMT1,GART,MTHFD2,DHFRL1,MTHFD2L,MTR
ko04666	Fc gamma R-mediated phagocytosis	0.423645113101966	-0.858859171629107	92	25	0.0140056022408964	1785	6908	10163,5058,10451,3636,8936,5894,208,55616,5604,8394,10552,5581,1399,7408,998,8976,5296,1785,8503,6198,4082,10109,382,56848,6199	WASF2,PAK1,VAV3,INPPL1,WASF1,RAF1,AKT2,ASAP3,MAP2K1,PIP5K1A,ARPC1A,PRKCE,CRKL,VASP,CDC42,WASL,PIK3R2,DNM2,PIK3R3,RPS6KB1,MARCKS,ARPC2,ARF6,SPHK2,RPS6KB2
hsa04666	Fc gamma R-mediated phagocytosis	0.423645113101966	-0.858859171629107	92	25	0.0140056022408964	1785	6908	10163,5058,10451,3636,8936,5894,208,55616,5604,8394,10552,5581,1399,7408,998,8976,5296,1785,8503,6198,4082,10109,382,56848,6199	WASF2,PAK1,VAV3,INPPL1,WASF1,RAF1,AKT2,ASAP3,MAP2K1,PIP5K1A,ARPC1A,PRKCE,CRKL,VASP,CDC42,WASL,PIK3R2,DNM2,PIK3R3,RPS6KB1,MARCKS,ARPC2,ARF6,SPHK2,RPS6KB2
hsa00630	Glyoxylate and dicarboxylate metabolism	0.440813740958745	-0.819132848855372	28	8	0.00448179271708683	1785	6908	50,6470,283871,4594,1738,4191,2653,1431	ACO2,SHMT1,PGP,MUT,DLD,MDH2,GCSH,CS
ko00630	Glyoxylate and dicarboxylate metabolism	0.440813740958745	-0.819132848855372	28	8	0.00448179271708683	1785	6908	50,6470,283871,4594,1738,4191,2653,1431	ACO2,SHMT1,PGP,MUT,DLD,MDH2,GCSH,CS
hsa04622	RIG-I-like receptor signaling pathway	0.446499046304359	-0.806318014604351	70	19	0.0106442577030812	1785	6908	55593,1540,79671,7186,9140,80143,1147,64343,8772,1654,3592,8517,5300,3551,5601,9474,6885,5970,64135	OTUD5,CYLD,NLRX1,TRAF2,ATG12,SIKE1,CHUK,AZI2,FADD,DDX3X,IL12A,IKBKG,PIN1,IKBKB,MAPK9,ATG5,MAP3K7,RELA,IFIH1
ko04622	RIG-I-like receptor signaling pathway	0.446499046304359	-0.806318014604351	70	19	0.0106442577030812	1785	6908	55593,1540,79671,7186,9140,80143,1147,64343,8772,1654,3592,8517,5300,3551,5601,9474,6885,5970,64135	OTUD5,CYLD,NLRX1,TRAF2,ATG12,SIKE1,CHUK,AZI2,FADD,DDX3X,IL12A,IKBKG,PIN1,IKBKB,MAPK9,ATG5,MAP3K7,RELA,IFIH1
hsa00480	Glutathione metabolism	0.448847070365475	-0.801073049779742	51	14	0.00784313725490196	1785	6908	373156,119391,79017,51056,2729,4259,6240,6241,51060,493869,5226,6611,2879,2937	GSTK1,GSTO2,GGCT,LAP3,GCLC,MGST3,RRM1,RRM2,TXNDC12,GPX8,PGD,SMS,GPX4,GSS
ko00480	Glutathione metabolism	0.448847070365475	-0.801073049779742	51	14	0.00784313725490196	1785	6908	373156,119391,79017,51056,2729,4259,6240,6241,51060,493869,2937,2879,6611,5226	GSTK1,GSTO2,GGCT,LAP3,GCLC,MGST3,RRM1,RRM2,TXNDC12,GPX8,GSS,GPX4,SMS,PGD
hsa00300	Lysine biosynthesis	0.450051343892497	-0.798393605187519	2	1	0.000560224089635854	1785	6908	501	ALDH7A1
ko00300	Lysine biosynthesis	0.450051343892497	-0.798393605187519	2	1	0.000560224089635854	1785	6908	501	ALDH7A1
ko00380	Tryptophan metabolism	0.464764532471885	-0.766224383430226	40	11	0.0061624649859944	1785	6908	883,3033,8942,55753,56267,4128,501,4967,2639,224,1545	CCBL1,HADH,KYNU,OGDHL,CCBL2,MAOA,ALDH7A1,OGDH,GCDH,ALDH3A2,CYP1B1
hsa00380	Tryptophan metabolism	0.464764532471885	-0.766224383430226	40	11	0.0061624649859944	1785	6908	883,3033,8942,55753,56267,4128,501,4967,2639,224,1545	CCBL1,HADH,KYNU,OGDHL,CCBL2,MAOA,ALDH7A1,OGDH,GCDH,ALDH3A2,CYP1B1
ko05230	Central carbon metabolism in cancer	0.470202181072871	-0.754592504280225	67	18	0.0100840336134454	1785	6908	5160,5163,2475,51548,208,5894,5604,7157,3939,3845,9997,2744,57103,4609,5296,8503,5224,4233	PDHA1,PDK1,MTOR,SIRT6,AKT2,RAF1,MAP2K1,TP53,LDHA,KRAS,SCO2,GLS,TIGAR,MYC,PIK3R2,PIK3R3,PGAM2,MET
hsa05230	Central carbon metabolism in cancer	0.470202181072871	-0.754592504280225	67	18	0.0100840336134454	1785	6908	5160,5163,2475,51548,208,5894,5604,7157,3939,3845,9997,2744,57103,4609,5296,8503,5224,4233	PDHA1,PDK1,MTOR,SIRT6,AKT2,RAF1,MAP2K1,TP53,LDHA,KRAS,SCO2,GLS,TIGAR,MYC,PIK3R2,PIK3R3,PGAM2,MET
ko00520	Amino sugar and nucleotide sugar metabolism	0.476643133738884	-0.740987215393586	48	13	0.00728291316526611	1785	6908	5372,4351,197258,7360,6675,10020,51167,7358,29925,5373,29926,55577,2582	PMM1,MPI,FUK,UGP2,UAP1,GNE,CYB5R4,UGDH,GMPPB,PMM2,GMPPA,NAGK,GALE
hsa00520	Amino sugar and nucleotide sugar metabolism	0.476643133738884	-0.740987215393586	48	13	0.00728291316526611	1785	6908	5372,4351,197258,7360,6675,10020,51167,7358,29925,5373,29926,55577,2582	PMM1,MPI,FUK,UGP2,UAP1,GNE,CYB5R4,UGDH,GMPPB,PMM2,GMPPA,NAGK,GALE
hsa00750	Vitamin B6 metabolism	0.4859218562699	-0.721707457577779	6	2	0.00112044817927171	1785	6908	55163,29968	PNPO,PSAT1
ko00750	Vitamin B6 metabolism	0.4859218562699	-0.721707457577779	6	2	0.00112044817927171	1785	6908	55163,29968	PNPO,PSAT1
hsa04310	Wnt signaling pathway	0.488861168498489	-0.715676738818101	141	37	0.0207282913165266	1785	6908	23291,7157,324,1460,1488,2535,1452,5566,5663,3725,595,1499,57680,80326,4609,5601,4040,6885,9475,1856,8321,1454,23401,59343,6934,22943,80319,5467,817,8607,10023,2932,4776,27101,6907,8061,8945	FBXW11,TP53,APC,CSNK2B,CTBP2,FZD2,CSNK1A1,PRKACA,PSEN1,JUN,CCND1,CTNNB1,CHD8,WNT10A,MYC,MAPK9,LRP6,MAP3K7,ROCK2,DVL2,FZD1,CSNK1E,FRAT2,SENP2,TCF7L2,DKK1,CXXC4,PPARD,CAMK2D,RUVBL1,FRAT1,GSK3B,NFATC4,CACYBP,TBL1X,FOSL1,BTRC
ko04310	Wnt signaling pathway	0.488861168498489	-0.715676738818101	141	37	0.0207282913165266	1785	6908	23291,7157,324,1460,1488,2535,1452,5566,5663,3725,595,1499,57680,80326,4609,5601,4040,6885,9475,1856,8321,1454,23401,59343,6934,22943,80319,5467,817,8607,10023,2932,4776,27101,6907,8061,8945	FBXW11,TP53,APC,CSNK2B,CTBP2,FZD2,CSNK1A1,PRKACA,PSEN1,JUN,CCND1,CTNNB1,CHD8,WNT10A,MYC,MAPK9,LRP6,MAP3K7,ROCK2,DVL2,FZD1,CSNK1E,FRAT2,SENP2,TCF7L2,DKK1,CXXC4,PPARD,CAMK2D,RUVBL1,FRAT1,GSK3B,NFATC4,CACYBP,TBL1X,FOSL1,BTRC
hsa00564	Glycerophospholipid metabolism	0.497059359483494	-0.699045824436898	95	25	0.0140056022408964	1785	6908	85465,8681,56895,84803,55500,10554,162466,8527,10162,81579,64900,253558,64850,79143,1119,1040,10555,10400,2820,23659,10908,10434,57678,5130,11313	EPT1,JMJD7-PLA2G4B,AGPAT4,GPAT3,ETNK1,AGPAT1,PHOSPHO1,DGKD,LPCAT3,PLA2G12A,LPIN3,LCLAT1,ETNPPL,MBOAT7,CHKA,CDS1,AGPAT2,PEMT,GPD2,PLA2G15,PNPLA6,LYPLA1,GPAM,PCYT1A,LYPLA2
ko00564	Glycerophospholipid metabolism	0.497059359483494	-0.699045824436898	95	25	0.0140056022408964	1785	6908	85465,56895,8681,84803,55500,10554,162466,8527,10162,81579,64900,253558,64850,79143,1040,1119,10555,10400,23659,2820,10908,10434,57678,5130,11313	EPT1,AGPAT4,JMJD7-PLA2G4B,GPAT3,ETNK1,AGPAT1,PHOSPHO1,DGKD,LPCAT3,PLA2G12A,LPIN3,LCLAT1,ETNPPL,MBOAT7,CDS1,CHKA,AGPAT2,PEMT,PLA2G15,GPD2,PNPLA6,LYPLA1,GPAM,PCYT1A,LYPLA2
ko00920	Sulfur metabolism	0.499540213492223	-0.694067176642146	10	3	0.00168067226890756	1785	6908	54205,58472,6821	CYCS,SQRDL,SUOX
hsa00920	Sulfur metabolism	0.499540213492223	-0.694067176642146	10	3	0.00168067226890756	1785	6908	54205,58472,6821	CYCS,SQRDL,SUOX
ko04915	Estrogen signaling pathway	0.500225499435619	-0.69269628335813	99	26	0.0145658263305322	1785	6908	64764,148327,468,7184,1388,208,5894,3326,3312,5604,3845,2100,2773,5566,2353,3304,805,3725,6464,5296,8503,2289,3320,2771,1386,6667	CREB3L2,CREB3L4,ATF4,HSP90B1,ATF6B,AKT2,RAF1,HSP90AB1,HSPA8,MAP2K1,KRAS,ESR2,GNAI3,PRKACA,FOS,HSPA1B,CALM2,JUN,SHC1,PIK3R2,PIK3R3,FKBP5,HSP90AA1,GNAI2,ATF2,SP1
hsa04915	Estrogen signaling pathway	0.500225499435619	-0.69269628335813	99	26	0.0145658263305322	1785	6908	64764,148327,468,7184,1388,208,5894,3326,3312,5604,3845,2100,2773,5566,2353,3304,805,3725,6464,5296,8503,2289,3320,2771,1386,6667	CREB3L2,CREB3L4,ATF4,HSP90B1,ATF6B,AKT2,RAF1,HSP90AB1,HSPA8,MAP2K1,KRAS,ESR2,GNAI3,PRKACA,FOS,HSPA1B,CALM2,JUN,SHC1,PIK3R2,PIK3R3,FKBP5,HSP90AA1,GNAI2,ATF2,SP1
ko00790	Folate biosynthesis	0.508143408320206	-0.676991571399834	14	4	0.00224089635854342	1785	6908	5805,8836,200895,2356	PTS,GGH,DHFRL1,FPGS
hsa00790	Folate biosynthesis	0.508143408320206	-0.676991571399834	14	4	0.00224089635854342	1785	6908	5805,8836,200895,2356	PTS,GGH,DHFRL1,FPGS
ko04520	Adherens junction	0.530381714971775	-0.634158314739843	73	19	0.0106442577030812	1785	6908	4008,10163,2241,8936,1495,7082,1460,87,6934,117178,5770,1499,998,8976,52,1500,6885,4233,7414	LMO7,WASF2,FER,WASF1,CTNNA1,TJP1,CSNK2B,ACTN1,TCF7L2,SSX2IP,PTPN1,CTNNB1,CDC42,WASL,ACP1,CTNND1,MAP3K7,MET,VCL
hsa04520	Adherens junction	0.530381714971775	-0.634158314739843	73	19	0.0106442577030812	1785	6908	4008,10163,2241,8936,1495,7082,1460,87,6934,117178,5770,1499,998,8976,52,1500,6885,4233,7414	LMO7,WASF2,FER,WASF1,CTNNA1,TJP1,CSNK2B,ACTN1,TCF7L2,SSX2IP,PTPN1,CTNNB1,CDC42,WASL,ACP1,CTNND1,MAP3K7,MET,VCL
ko04071	Sphingolipid signaling pathway	0.536022290675847	-0.623579531694251	120	31	0.0173669467787115	1785	6908	5170,208,5894,7186,6609,91012,5604,7157,427,3845,5526,9294,2773,9517,5581,2768,5529,5518,5601,5296,581,8503,5527,5521,4217,10558,2771,5970,56848,5528,9475	PDPK1,AKT2,RAF1,TRAF2,SMPD1,CERS5,MAP2K1,TP53,ASAH1,KRAS,PPP2R5B,S1PR2,GNAI3,SPTLC2,PRKCE,GNA12,PPP2R5E,PPP2R1A,MAPK9,PIK3R2,BAX,PIK3R3,PPP2R5C,PPP2R2B,MAP3K5,SPTLC1,GNAI2,RELA,SPHK2,PPP2R5D,ROCK2
hsa04071	Sphingolipid signaling pathway	0.536022290675847	-0.623579531694251	120	31	0.0173669467787115	1785	6908	5170,208,5894,7186,6609,91012,5604,7157,427,3845,5526,9294,2773,9517,5581,2768,5529,5518,5601,5296,581,8503,5527,5521,4217,10558,2771,5970,56848,5528,9475	PDPK1,AKT2,RAF1,TRAF2,SMPD1,CERS5,MAP2K1,TP53,ASAH1,KRAS,PPP2R5B,S1PR2,GNAI3,SPTLC2,PRKCE,GNA12,PPP2R5E,PPP2R1A,MAPK9,PIK3R2,BAX,PIK3R3,PPP2R5C,PPP2R2B,MAP3K5,SPTLC1,GNAI2,RELA,SPHK2,PPP2R5D,ROCK2
ko04145	Phagosome	0.5521698241442	-0.593899627585202	152	39	0.0218487394957983	1785	6908	3122,1781,4973,523,10383,23480,3133,3134,6890,821,8411,7037,3105,4074,811,23545,3107,200576,51606,529,9114,10381,3920,5289,7879,23673,9341,3109,535,5868,5869,3108,51382,53407,3688,9554,528,5878,203068	HLA-DRA,DYNC1I2,OLR1,ATP6V1A,TUBB4B,SEC61G,HLA-E,HLA-F,TAP1,CANX,EEA1,TFRC,HLA-A,M6PR,CALR,ATP6V0A2,HLA-C,PIKFYVE,ATP6V1H,ATP6V1E1,ATP6V0D1,TUBB3,LAMP2,PIK3C3,RAB7A,STX12,VAMP3,HLA-DMB,ATP6V0A1,RAB5A,RAB5B,HLA-DMA,ATP6V1D,STX18,ITGB1,SEC22B,ATP6V1C1,RAB5C,TUBB
hsa04145	Phagosome	0.5521698241442	-0.593899627585202	152	39	0.0218487394957983	1785	6908	3122,1781,4973,523,10383,23480,3133,3134,6890,821,8411,7037,3105,4074,811,23545,3107,200576,51606,529,9114,10381,3920,5289,7879,23673,9341,3109,535,5868,5869,3108,51382,53407,3688,9554,528,5878,203068	HLA-DRA,DYNC1I2,OLR1,ATP6V1A,TUBB4B,SEC61G,HLA-E,HLA-F,TAP1,CANX,EEA1,TFRC,HLA-A,M6PR,CALR,ATP6V0A2,HLA-C,PIKFYVE,ATP6V1H,ATP6V1E1,ATP6V0D1,TUBB3,LAMP2,PIK3C3,RAB7A,STX12,VAMP3,HLA-DMB,ATP6V0A1,RAB5A,RAB5B,HLA-DMA,ATP6V1D,STX18,ITGB1,SEC22B,ATP6V1C1,RAB5C,TUBB
hsa00531	Glycosaminoglycan degradation	0.568325599135475	-0.565060786584508	19	5	0.00280112044817927	1785	6908	3373,8372,10855,138050,2990	HYAL1,HYAL3,HPSE,HGSNAT,GUSB
ko00531	Glycosaminoglycan degradation	0.568325599135475	-0.565060786584508	19	5	0.00280112044817927	1785	6908	3373,8372,138050,10855,2990	HYAL1,HYAL3,HGSNAT,HPSE,GUSB
hsa00340	Histidine metabolism	0.568614132610251	-0.564553224973433	23	6	0.00336134453781513	1785	6908	4128,501,221,55748,144193,224	MAOA,ALDH7A1,ALDH3B1,CNDP2,AMDHD1,ALDH3A2
ko01040	Biosynthesis of unsaturated fatty acids	0.568614132610251	-0.564553224973433	23	6	0.00336134453781513	1785	6908	3992,60481,9415,8310,51,79966	FADS1,ELOVL5,FADS2,ACOX3,ACOX1,SCD5
hsa01040	Biosynthesis of unsaturated fatty acids	0.568614132610251	-0.564553224973433	23	6	0.00336134453781513	1785	6908	3992,60481,9415,8310,79966,51	FADS1,ELOVL5,FADS2,ACOX3,SCD5,ACOX1
ko00340	Histidine metabolism	0.568614132610251	-0.564553224973433	23	6	0.00336134453781513	1785	6908	4128,501,221,55748,144193,224	MAOA,ALDH7A1,ALDH3B1,CNDP2,AMDHD1,ALDH3A2
ko04320	Dorso-ventral axis formation	0.569311481837363	-0.563327574886019	27	7	0.00392156862745098	1785	6908	22849,3845,84501,80315,2114,132864,5604	CPEB3,KRAS,SPIRE2,CPEB4,ETS2,CPEB2,MAP2K1
hsa04320	Dorso-ventral axis formation	0.569311481837363	-0.563327574886019	27	7	0.00392156862745098	1785	6908	22849,3845,84501,80315,2114,132864,5604	CPEB3,KRAS,SPIRE2,CPEB4,ETS2,CPEB2,MAP2K1
ko04966	Collecting duct acid secretion	0.569311481837363	-0.563327574886019	27	7	0.00392156862745098	1785	6908	23545,535,51382,528,523,529,9114	ATP6V0A2,ATP6V0A1,ATP6V1D,ATP6V1C1,ATP6V1A,ATP6V1E1,ATP6V0D1
hsa04966	Collecting duct acid secretion	0.569311481837363	-0.563327574886019	27	7	0.00392156862745098	1785	6908	23545,535,51382,528,523,529,9114	ATP6V0A2,ATP6V0A1,ATP6V1D,ATP6V1C1,ATP6V1A,ATP6V1E1,ATP6V0D1
hsa04623	Cytosolic DNA-sensing pathway	0.580391148009629	-0.544053009622475	63	16	0.00896358543417367	1785	6908	661,8517,115004,51082,5440,3569,171568,3551,5434,1147,103,55703,5970,51728,11128,10621	POLR3D,IKBKG,MB21D1,POLR1D,POLR2K,IL6,POLR3H,IKBKB,POLR2E,CHUK,ADAR,POLR3B,RELA,POLR3K,POLR3A,POLR3F
ko04623	Cytosolic DNA-sensing pathway	0.580391148009629	-0.544053009622475	63	16	0.00896358543417367	1785	6908	661,8517,115004,51082,5440,3569,171568,3551,5434,1147,103,55703,5970,51728,11128,10621	POLR3D,IKBKG,MB21D1,POLR1D,POLR2K,IL6,POLR3H,IKBKB,POLR2E,CHUK,ADAR,POLR3B,RELA,POLR3K,POLR3A,POLR3F
hsa05322	Systemic lupus erythematosus	0.582895225792076	-0.539747824404943	134	34	0.019047619047619	1785	6908	3122,3015,8367,55766,85235,8350,8969,317772,8347,8360,440689,8365,8329,8364,653604,8332,3017,8331,8336,723790,3109,85236,3021,87,8340,8363,8368,94239,8330,3108,3012,8362,3014,128312	HLA-DRA,H2AFZ,HIST1H4E,H2AFJ,HIST1H2AH,HIST1H3A,HIST1H2AG,HIST2H2AB,HIST1H2BC,HIST1H4D,HIST2H2BF,HIST1H4H,HIST1H2AI,HIST1H4C,HIST2H3D,HIST1H2AL,HIST1H2BD,HIST1H2AJ,HIST1H2AM,HIST2H2AA4,HLA-DMB,HIST1H2BK,H3F3B,ACTN1,HIST1H2BL,HIST1H4J,HIST1H4L,H2AFV,HIST1H2AK,HLA-DMA,HIST1H2AE,HIST1H4K,H2AFX,HIST3H2BB
ko05162	Measles	0.582895225792076	-0.539747824404943	134	34	0.019047619047619	1785	6908	9451,7157,1147,1460,6777,440275,595,3592,5296,10379,1027,8503,3717,103,6885,3459,5970,6774,1021,7128,1019,208,3312,1796,868,10399,7297,8667,6773,3304,3569,6772,2932,64135	EIF2AK3,TP53,CHUK,CSNK2B,STAT5B,EIF2AK4,CCND1,IL12A,PIK3R2,IRF9,CDKN1B,PIK3R3,JAK2,ADAR,MAP3K7,IFNGR1,RELA,STAT3,CDK6,TNFAIP3,CDK4,AKT2,HSPA8,DOK1,CBLB,GNB2L1,TYK2,EIF3H,STAT2,HSPA1B,IL6,STAT1,GSK3B,IFIH1
hsa05162	Measles	0.582895225792076	-0.539747824404943	134	34	0.019047619047619	1785	6908	9451,7157,1147,1460,6777,440275,595,3592,5296,10379,1027,8503,3717,103,6885,3459,5970,6774,1021,7128,1019,208,3312,1796,868,10399,7297,8667,6773,3304,3569,6772,2932,64135	EIF2AK3,TP53,CHUK,CSNK2B,STAT5B,EIF2AK4,CCND1,IL12A,PIK3R2,IRF9,CDKN1B,PIK3R3,JAK2,ADAR,MAP3K7,IFNGR1,RELA,STAT3,CDK6,TNFAIP3,CDK4,AKT2,HSPA8,DOK1,CBLB,GNB2L1,TYK2,EIF3H,STAT2,HSPA1B,IL6,STAT1,GSK3B,IFIH1
ko05322	Systemic lupus erythematosus	0.582895225792076	-0.539747824404943	134	34	0.019047619047619	1785	6908	3122,3015,8367,55766,85235,8350,8969,317772,8347,8360,440689,8365,8329,8364,653604,8332,3017,8331,8336,723790,3109,85236,3021,87,8340,8363,8368,94239,8330,3108,3012,8362,3014,128312	HLA-DRA,H2AFZ,HIST1H4E,H2AFJ,HIST1H2AH,HIST1H3A,HIST1H2AG,HIST2H2AB,HIST1H2BC,HIST1H4D,HIST2H2BF,HIST1H4H,HIST1H2AI,HIST1H4C,HIST2H3D,HIST1H2AL,HIST1H2BD,HIST1H2AJ,HIST1H2AM,HIST2H2AA4,HLA-DMB,HIST1H2BK,H3F3B,ACTN1,HIST1H2BL,HIST1H4J,HIST1H4L,H2AFV,HIST1H2AK,HLA-DMA,HIST1H2AE,HIST1H4K,H2AFX,HIST3H2BB
hsa05218	Melanoma	0.583041065452436	-0.539497656943452	71	18	0.0100840336134454	1785	6908	673,1019,5894,208,5604,7157,1871,3845,572,595,369,5296,4286,8503,4233,1870,1021,1029	BRAF,CDK4,RAF1,AKT2,MAP2K1,TP53,E2F3,KRAS,BAD,CCND1,ARAF,PIK3R2,MITF,PIK3R3,MET,E2F2,CDK6,CDKN2A
ko05218	Melanoma	0.583041065452436	-0.539497656943452	71	18	0.0100840336134454	1785	6908	673,1019,5894,208,5604,7157,1871,3845,572,595,369,5296,4286,8503,4233,1870,1021,1029	BRAF,CDK4,RAF1,AKT2,MAP2K1,TP53,E2F3,KRAS,BAD,CCND1,ARAF,PIK3R2,MITF,PIK3R3,MET,E2F2,CDK6,CDKN2A
hsa04390	Hippo signaling pathway	0.589786784160554	-0.527994190175586	154	39	0.0218487394957983	1785	6908	23291,26524,3397,4771,659,1495,4092,3398,324,7531,2535,329,654,595,1490,1499,5518,3993,80326,4609,5584,5521,7159,1856,8321,7003,1454,1742,10971,60485,6934,7532,332,5500,2932,84962,7534,7533,8945	FBXW11,LATS2,ID1,NF2,BMPR2,CTNNA1,SMAD7,ID2,APC,YWHAE,FZD2,BIRC2,BMP6,CCND1,CTGF,CTNNB1,PPP2R1A,LLGL2,WNT10A,MYC,PRKCI,PPP2R2B,TP53BP2,DVL2,FZD1,TEAD1,CSNK1E,DLG4,YWHAQ,SAV1,TCF7L2,YWHAG,BIRC5,PPP1CB,GSK3B,AJUBA,YWHAZ,YWHAH,BTRC
ko04390	Hippo signaling pathway	0.589786784160554	-0.527994190175586	154	39	0.0218487394957983	1785	6908	23291,26524,3397,4771,659,1495,4092,3398,324,7531,2535,329,654,595,1490,1499,5518,3993,80326,4609,5584,5521,7159,1856,8321,7003,1454,1742,10971,60485,6934,7532,332,5500,2932,84962,7534,7533,8945	FBXW11,LATS2,ID1,NF2,BMPR2,CTNNA1,SMAD7,ID2,APC,YWHAE,FZD2,BIRC2,BMP6,CCND1,CTGF,CTNNB1,PPP2R1A,LLGL2,WNT10A,MYC,PRKCI,PPP2R2B,TP53BP2,DVL2,FZD1,TEAD1,CSNK1E,DLG4,YWHAQ,SAV1,TCF7L2,YWHAG,BIRC5,PPP1CB,GSK3B,AJUBA,YWHAZ,YWHAH,BTRC
ko00785	Lipoic acid metabolism	0.592197065175652	-0.523915819126231	3	1	0.000560224089635854	1785	6908	51601	LIPT1
ko01220	Degradation of aromatic compounds	0.592197065175652	-0.523915819126231	3	1	0.000560224089635854	1785	6908	10327	AKR1A1
hsa01220	Degradation of aromatic compounds	0.592197065175652	-0.523915819126231	3	1	0.000560224089635854	1785	6908	10327	AKR1A1
hsa00785	Lipoic acid metabolism	0.592197065175652	-0.523915819126231	3	1	0.000560224089635854	1785	6908	51601	LIPT1
hsa05164	Influenza A	0.59619599152422	-0.517185821135106	174	44	0.0246498599439776	1785	6908	3122,79671,10625,8480,5894,5604,9451,10482,54205,440275,3337,5606,3725,3592,100529063,3551,5296,5601,10379,8503,3717,103,3459,1386,5970,29107,5609,208,3312,842,3109,11100,7416,7297,6773,3304,3108,7514,5608,3569,2224,6772,2932,64135	HLA-DRA,NLRX1,IVNS1ABP,RAE1,RAF1,MAP2K1,EIF2AK3,NXF1,CYCS,EIF2AK4,DNAJB1,MAP2K3,JUN,IL12A,BCL2L2-PABPN1,IKBKB,PIK3R2,MAPK9,IRF9,PIK3R3,JAK2,ADAR,IFNGR1,ATF2,RELA,NXT1,MAP2K7,AKT2,HSPA8,CASP9,HLA-DMB,HNRNPUL1,VDAC1,TYK2,STAT2,HSPA1B,HLA-DMA,XPO1,MAP2K6,IL6,FDPS,STAT1,GSK3B,IFIH1
ko05164	Influenza A	0.59619599152422	-0.517185821135106	174	44	0.0246498599439776	1785	6908	3122,79671,10625,8480,5894,5604,9451,10482,54205,440275,3337,5606,3725,3592,100529063,3551,5296,5601,10379,8503,3717,103,3459,1386,5970,29107,5609,208,3312,842,3109,11100,7416,7297,6773,3304,3108,7514,5608,3569,2224,6772,2932,64135	HLA-DRA,NLRX1,IVNS1ABP,RAE1,RAF1,MAP2K1,EIF2AK3,NXF1,CYCS,EIF2AK4,DNAJB1,MAP2K3,JUN,IL12A,BCL2L2-PABPN1,IKBKB,PIK3R2,MAPK9,IRF9,PIK3R3,JAK2,ADAR,IFNGR1,ATF2,RELA,NXT1,MAP2K7,AKT2,HSPA8,CASP9,HLA-DMB,HNRNPUL1,VDAC1,TYK2,STAT2,HSPA1B,HLA-DMA,XPO1,MAP2K6,IL6,FDPS,STAT1,GSK3B,IFIH1
hsa01212	Fatty acid metabolism	0.60789796907815	-0.497748225114517	48	12	0.00672268907563025	1785	6908	3992,9415,60481,9374,3033,79966,51,3032,51102,27349,54995,8310	FADS1,FADS2,ELOVL5,PPT2,HADH,SCD5,ACOX1,HADHB,MECR,MCAT,OXSM,ACOX3
ko01212	Fatty acid metabolism	0.60789796907815	-0.497748225114517	48	12	0.00672268907563025	1785	6908	3992,9415,60481,9374,3033,79966,51,3032,51102,27349,54995,8310	FADS1,FADS2,ELOVL5,PPT2,HADH,SCD5,ACOX1,HADHB,MECR,MCAT,OXSM,ACOX3
hsa05202	Transcriptional misregulation in cancer	0.614489203402827	-0.486963919857286	179	45	0.0252100840336134	1785	6908	2130,55204,7403,1848,3728,5966,6929,2119,7157,3398,8350,598,3207,25942,8864,466,6760,4609,604,1027,653604,4299,4233,4297,2115,5970,4211,6667,7709,5914,330,8861,3021,64083,6257,8148,8464,3569,7030,8013,5546,2521,30012,1649,3066	EWSR1,GOLPH3L,KDM6A,DUSP6,JUP,REL,TCF3,ETV5,TP53,ID2,HIST1H3A,BCL2L1,HOXA11,SIN3A,PER2,ATF1,SS18,MYC,BCL6,CDKN1B,HIST2H3D,AFF1,MET,KMT2A,ETV1,RELA,MEIS1,SP1,ZBTB17,RARA,BIRC3,LDB1,H3F3B,GOLPH3,RXRB,TAF15,SUPT3H,IL6,TFE3,NR4A3,PRCC,FUS,TLX3,DDIT3,HDAC2
ko05202	Transcriptional misregulation in cancer	0.614489203402827	-0.486963919857286	179	45	0.0252100840336134	1785	6908	2130,55204,7403,1848,3728,5966,6929,2119,7157,3398,8350,598,3207,25942,8864,466,6760,4609,604,1027,653604,4299,4233,4297,2115,5970,4211,6667,7709,5914,330,8861,3021,64083,6257,8148,8464,3569,7030,8013,5546,2521,30012,1649,3066	EWSR1,GOLPH3L,KDM6A,DUSP6,JUP,REL,TCF3,ETV5,TP53,ID2,HIST1H3A,BCL2L1,HOXA11,SIN3A,PER2,ATF1,SS18,MYC,BCL6,CDKN1B,HIST2H3D,AFF1,MET,KMT2A,ETV1,RELA,MEIS1,SP1,ZBTB17,RARA,BIRC3,LDB1,H3F3B,GOLPH3,RXRB,TAF15,SUPT3H,IL6,TFE3,NR4A3,PRCC,FUS,TLX3,DDIT3,HDAC2
hsa04010	MAPK signaling pathway	0.632630549129523	-0.457868677892572	255	64	0.0358543417366947	1785	6908	673,5607,1848,9175,4763,8681,7186,5894,5604,7157,23162,1147,9252,3925,5495,5566,1847,5606,59283,1399,3725,6196,998,4609,783,3551,5601,5971,11221,5494,4791,6885,5598,1386,5970,1843,4215,5058,627,468,6237,5609,7867,3164,208,3312,51295,8550,100506012,3845,2002,2353,3304,2768,8517,1616,5608,4616,4296,6722,784,4217,10454,1649	BRAF,MAP2K5,DUSP6,MAP3K13,NF1,JMJD7-PLA2G4B,TRAF2,RAF1,MAP2K1,TP53,MAPK8IP3,CHUK,RPS6KA5,STMN1,PPM1B,PRKACA,DUSP5,MAP2K3,CACNG8,CRKL,JUN,RPS6KA2,CDC42,MYC,CACNB2,IKBKB,MAPK9,RELB,DUSP10,PPM1A,NFKB2,MAP3K7,MAPK7,ATF2,RELA,DUSP1,MAP3K3,PAK1,BDNF,ATF4,RRAS,MAP2K7,MAPKAPK3,NR4A1,AKT2,HSPA8,ECSIT,MAPKAPK5,PPP5D1,KRAS,ELK1,FOS,HSPA1B,GNA12,IKBKG,DAXX,MAP2K6,GADD45B,MAP3K11,SRF,CACNB3,MAP3K5,TAB1,DDIT3
ko04010	MAPK signaling pathway	0.632630549129523	-0.457868677892572	255	64	0.0358543417366947	1785	6908	673,5607,1848,9175,4763,7186,8681,5894,5604,7157,23162,1147,9252,3925,5495,5566,1847,5606,1399,59283,3725,6196,998,783,4609,3551,5601,5971,11221,5494,6885,4791,5598,1386,5970,1843,4215,5058,627,468,5609,6237,7867,3164,208,3312,8550,100506012,51295,3845,2002,2353,3304,2768,8517,1616,5608,4616,4296,6722,784,4217,10454,1649	BRAF,MAP2K5,DUSP6,MAP3K13,NF1,TRAF2,JMJD7-PLA2G4B,RAF1,MAP2K1,TP53,MAPK8IP3,CHUK,RPS6KA5,STMN1,PPM1B,PRKACA,DUSP5,MAP2K3,CRKL,CACNG8,JUN,RPS6KA2,CDC42,CACNB2,MYC,IKBKB,MAPK9,RELB,DUSP10,PPM1A,MAP3K7,NFKB2,MAPK7,ATF2,RELA,DUSP1,MAP3K3,PAK1,BDNF,ATF4,MAP2K7,RRAS,MAPKAPK3,NR4A1,AKT2,HSPA8,MAPKAPK5,PPP5D1,ECSIT,KRAS,ELK1,FOS,HSPA1B,GNA12,IKBKG,DAXX,MAP2K6,GADD45B,MAP3K11,SRF,CACNB3,MAP3K5,TAB1,DDIT3
hsa04612	Antigen processing and presentation	0.635743596368087	-0.452959947293614	77	19	0.0106442577030812	1785	6908	3122,3134,3326,3133,3309,3312,3109,6890,567,821,3105,3304,811,3108,3308,4802,3320,3107,10197	HLA-DRA,HLA-F,HSP90AB1,HLA-E,HSPA5,HSPA8,HLA-DMB,TAP1,B2M,CANX,HLA-A,HSPA1B,CALR,HLA-DMA,HSPA4,NFYC,HSP90AA1,HLA-C,PSME3
ko04612	Antigen processing and presentation	0.635743596368087	-0.452959947293614	77	19	0.0106442577030812	1785	6908	3122,3134,3326,3133,3309,3312,3109,6890,567,821,3105,3304,811,3108,3308,4802,3320,3107,10197	HLA-DRA,HLA-F,HSP90AB1,HLA-E,HSPA5,HSPA8,HLA-DMB,TAP1,B2M,CANX,HLA-A,HSPA1B,CALR,HLA-DMA,HSPA4,NFYC,HSP90AA1,HLA-C,PSME3
hsa04210	Apoptosis	0.635845767512331	-0.452799248962272	85	21	0.0117647058823529	1785	6908	330,7186,208,842,2021,7157,54205,1147,598,5566,329,8772,572,8517,840,3551,5296,581,8503,5970,5573	BIRC3,TRAF2,AKT2,CASP9,ENDOG,TP53,CYCS,CHUK,BCL2L1,PRKACA,BIRC2,FADD,BAD,IKBKG,CASP7,IKBKB,PIK3R2,BAX,PIK3R3,RELA,PRKAR1A
ko04210	Apoptosis	0.635845767512331	-0.452799248962272	85	21	0.0117647058823529	1785	6908	330,7186,208,842,2021,7157,54205,1147,598,5566,329,8772,572,8517,840,3551,5296,581,8503,5970,5573	BIRC3,TRAF2,AKT2,CASP9,ENDOG,TP53,CYCS,CHUK,BCL2L1,PRKACA,BIRC2,FADD,BAD,IKBKG,CASP7,IKBKB,PIK3R2,BAX,PIK3R3,RELA,PRKAR1A
ko05132	Salmonella infection	0.635845767512331	-0.452799248962272	85	21	0.0117647058823529	1785	6908	10163,1781,8936,7879,4627,3831,7082,2920,10552,4628,2353,5586,3725,998,3569,8976,5601,10109,3459,5970,9475	WASF2,DYNC1I2,WASF1,RAB7A,MYH9,KLC1,TJP1,CXCL2,ARPC1A,MYH10,FOS,PKN2,JUN,CDC42,IL6,WASL,MAPK9,ARPC2,IFNGR1,RELA,ROCK2
hsa05132	Salmonella infection	0.635845767512331	-0.452799248962272	85	21	0.0117647058823529	1785	6908	10163,1781,8936,7879,4627,3831,7082,2920,10552,4628,2353,5586,3725,998,3569,8976,5601,10109,3459,5970,9475	WASF2,DYNC1I2,WASF1,RAB7A,MYH9,KLC1,TJP1,CXCL2,ARPC1A,MYH10,FOS,PKN2,JUN,CDC42,IL6,WASL,MAPK9,ARPC2,IFNGR1,RELA,ROCK2
hsa00062	Fatty acid elongation	0.658065112969258	-0.418451396672298	25	6	0.00336134453781513	1785	6908	60481,9374,3033,79993,3032,51102	ELOVL5,PPT2,HADH,ELOVL7,HADHB,MECR
ko00062	Fatty acid elongation	0.658065112969258	-0.418451396672298	25	6	0.00336134453781513	1785	6908	60481,9374,3033,79993,3032,51102	ELOVL5,PPT2,HADH,ELOVL7,HADHB,MECR
ko01210	2-Oxocarboxylic acid metabolism	0.676251590651782	-0.391190096658916	17	4	0.00224089635854342	1785	6908	2805,50,3420,1431	GOT1,ACO2,IDH3B,CS
hsa00360	Phenylalanine metabolism	0.676251590651782	-0.391190096658916	17	4	0.00224089635854342	1785	6908	4282,4128,2805,221	MIF,MAOA,GOT1,ALDH3B1
hsa01210	2-Oxocarboxylic acid metabolism	0.676251590651782	-0.391190096658916	17	4	0.00224089635854342	1785	6908	2805,50,3420,1431	GOT1,ACO2,IDH3B,CS
ko00360	Phenylalanine metabolism	0.676251590651782	-0.391190096658916	17	4	0.00224089635854342	1785	6908	4282,4128,221,2805	MIF,MAOA,ALDH3B1,GOT1
hsa04380	Osteoclast differentiation	0.677615881647982	-0.389174697831619	131	32	0.0179271708683473	1785	6908	1540,5609,208,7186,5604,2274,1147,2355,2353,7297,6773,3725,8517,8651,8878,5608,3551,4286,3726,2354,5601,5296,6772,10379,5971,8503,6885,3459,4791,10454,8061,5970	CYLD,MAP2K7,AKT2,TRAF2,MAP2K1,FHL2,CHUK,FOSL2,FOS,TYK2,STAT2,JUN,IKBKG,SOCS1,SQSTM1,MAP2K6,IKBKB,MITF,JUNB,FOSB,MAPK9,PIK3R2,STAT1,IRF9,RELB,PIK3R3,MAP3K7,IFNGR1,NFKB2,TAB1,FOSL1,RELA
ko04380	Osteoclast differentiation	0.677615881647982	-0.389174697831619	131	32	0.0179271708683473	1785	6908	1540,5609,208,7186,5604,2274,1147,2355,2353,7297,6773,3725,8517,8651,8878,5608,3551,4286,3726,2354,5601,5296,6772,10379,5971,8503,6885,3459,4791,10454,8061,5970	CYLD,MAP2K7,AKT2,TRAF2,MAP2K1,FHL2,CHUK,FOSL2,FOS,TYK2,STAT2,JUN,IKBKG,SOCS1,SQSTM1,MAP2K6,IKBKB,MITF,JUNB,FOSB,MAPK9,PIK3R2,STAT1,IRF9,RELB,PIK3R3,MAP3K7,IFNGR1,NFKB2,TAB1,FOSL1,RELA
hsa04064	NF-kappa B signaling pathway	0.681002428027338	-0.384189407453756	91	22	0.0123249299719888	1785	6908	55367,7128,330,257397,7186,10892,1147,1460,2920,598,7329,329,23085,8517,5743,4616,3551,5971,6885,4791,10454,5970	PIDD1,TNFAIP3,BIRC3,TAB3,TRAF2,MALT1,CHUK,CSNK2B,CXCL2,BCL2L1,UBE2I,BIRC2,ERC1,IKBKG,PTGS2,GADD45B,IKBKB,RELB,MAP3K7,NFKB2,TAB1,RELA
hsa04146	Peroxisome	0.682770121202385	-0.381597048242534	83	20	0.0112044817927171	1785	6908	5824,3295,5193,10654,84769,5192,5052,1891,8799,373156,5825,55670,51,8504,4358,5194,11264,84188,8310,10005	PEX19,HSD17B4,PEX12,PMVK,MPV17L2,PEX10,PRDX1,ECH1,PEX11B,GSTK1,ABCD3,PEX26,ACOX1,PEX3,MPV17,PEX13,PXMP4,FAR1,ACOX3,ACOT8
ko04146	Peroxisome	0.682770121202385	-0.381597048242534	83	20	0.0112044817927171	1785	6908	5824,3295,5193,10654,84769,5192,5052,1891,8799,373156,5825,55670,51,8504,4358,5194,11264,84188,8310,10005	PEX19,HSD17B4,PEX12,PMVK,MPV17L2,PEX10,PRDX1,ECH1,PEX11B,GSTK1,ABCD3,PEX26,ACOX1,PEX3,MPV17,PEX13,PXMP4,FAR1,ACOX3,ACOT8
hsa00562	Inositol phosphate metabolism	0.686617653967066	-0.375977686131995	71	17	0.00952380952380952	1785	6908	5289,3636,4329,3633,51477,8394,8867,55361,51763,8396,64768,5298,9110,253430,138429,200576,3613	PIK3C3,INPPL1,ALDH6A1,INPP5B,ISYNA1,PIP5K1A,SYNJ1,PI4K2A,INPP5K,PIP4K2B,IPPK,PI4KB,MTMR4,IPMK,PIP5KL1,PIKFYVE,IMPA2
ko00562	Inositol phosphate metabolism	0.686617653967066	-0.375977686131995	71	17	0.00952380952380952	1785	6908	5289,3636,4329,3633,51477,8394,8867,55361,51763,8396,64768,5298,9110,253430,138429,200576,3613	PIK3C3,INPPL1,ALDH6A1,INPP5B,ISYNA1,PIP5K1A,SYNJ1,PI4K2A,INPP5K,PIP4K2B,IPPK,PI4KB,MTMR4,IPMK,PIP5KL1,PIKFYVE,IMPA2
ko04721	Synaptic vesicle cycle	0.690289315008737	-0.370644472157191	63	15	0.00840336134453781	1785	6908	51382,523,160,1213,5864,1785,23545,535,163,6616,528,51606,529,1175,9114	ATP6V1D,ATP6V1A,AP2A1,CLTC,RAB3A,DNM2,ATP6V0A2,ATP6V0A1,AP2B1,SNAP25,ATP6V1C1,ATP6V1H,ATP6V1E1,AP2S1,ATP6V0D1
hsa04721	Synaptic vesicle cycle	0.690289315008737	-0.370644472157191	63	15	0.00840336134453781	1785	6908	51382,523,160,1213,5864,1785,23545,535,163,6616,528,51606,529,1175,9114	ATP6V1D,ATP6V1A,AP2A1,CLTC,RAB3A,DNM2,ATP6V0A2,ATP6V0A1,AP2B1,SNAP25,ATP6V1C1,ATP6V1H,ATP6V1E1,AP2S1,ATP6V0D1
hsa03450	Non-homologous end-joining	0.692409225131745	-0.367578132354996	13	3	0.00168067226890756	1785	6908	2547,2237,7520	XRCC6,FEN1,XRCC5
ko03450	Non-homologous end-joining	0.692409225131745	-0.367578132354996	13	3	0.00168067226890756	1785	6908	2547,2237,7520	XRCC6,FEN1,XRCC5
ko00561	Glycerolipid metabolism	0.692573939008724	-0.367340275488544	59	14	0.00784313725490196	1785	6908	2710,10555,56895,84803,10554,231,501,9388,8527,57678,64900,253558,224,10327	GK,AGPAT2,AGPAT4,GPAT3,AGPAT1,AKR1B1,ALDH7A1,LIPG,DGKD,GPAM,LPIN3,LCLAT1,ALDH3A2,AKR1A1
hsa00561	Glycerolipid metabolism	0.692573939008724	-0.367340275488544	59	14	0.00784313725490196	1785	6908	2710,10555,56895,84803,10554,231,501,8527,9388,57678,64900,253558,224,10327	GK,AGPAT2,AGPAT4,GPAT3,AGPAT1,AKR1B1,ALDH7A1,DGKD,LIPG,GPAM,LPIN3,LCLAT1,ALDH3A2,AKR1A1
ko00471	D-Glutamine and D-glutamate metabolism	0.697617519725481	-0.360084292417346	4	1	0.000560224089635854	1785	6908	2744	GLS
hsa00471	D-Glutamine and D-glutamate metabolism	0.697617519725481	-0.360084292417346	4	1	0.000560224089635854	1785	6908	2744	GLS
ko00600	Sphingolipid metabolism	0.701992296496501	-0.353832848668245	47	11	0.0061624649859944	1785	6908	55512,10825,6609,2629,91012,427,55627,10558,9517,56848,4758	SMPD3,NEU3,SMPD1,GBA,CERS5,ASAH1,SMPD4,SPTLC1,SPTLC2,SPHK2,NEU1
hsa00600	Sphingolipid metabolism	0.701992296496501	-0.353832848668245	47	11	0.0061624649859944	1785	6908	55512,10825,6609,2629,91012,427,55627,10558,56848,9517,4758	SMPD3,NEU3,SMPD1,GBA,CERS5,ASAH1,SMPD4,SPTLC1,SPHK2,SPTLC2,NEU1
hsa04940	Type I diabetes mellitus	0.706317441423146	-0.347690508800023	43	10	0.00560224089635854	1785	6908	3122,3108,3592,3382,3134,3133,3109,3107,1363,3105	HLA-DRA,HLA-DMA,IL12A,ICA1,HLA-F,HLA-E,HLA-DMB,HLA-C,CPE,HLA-A
ko04940	Type I diabetes mellitus	0.706317441423146	-0.347690508800023	43	10	0.00560224089635854	1785	6908	3122,3108,3592,3382,3134,3133,3109,3107,1363,3105	HLA-DRA,HLA-DMA,IL12A,ICA1,HLA-F,HLA-E,HLA-DMB,HLA-C,CPE,HLA-A
ko04960	Aldosterone-regulated sodium reabsorption	0.71148618903791	-0.340399272690648	39	9	0.00504201680672269	1785	6908	5170,476,5296,6446,8503,23327,3845,483,4306	PDPK1,ATP1A1,PIK3R2,SGK1,PIK3R3,NEDD4L,KRAS,ATP1B3,NR3C2
hsa04960	Aldosterone-regulated sodium reabsorption	0.71148618903791	-0.340399272690648	39	9	0.00504201680672269	1785	6908	5170,476,5296,6446,8503,23327,3845,483,4306	PDPK1,ATP1A1,PIK3R2,SGK1,PIK3R3,NEDD4L,KRAS,ATP1B3,NR3C2
ko04728	Dopaminergic synapse	0.713733183193919	-0.337246079488899	129	31	0.0173669467787115	1785	6908	64764,6323,148327,468,1388,2931,208,2788,5526,2773,5566,2353,2783,805,817,5529,5518,59345,406,5601,5500,5527,4128,2932,51764,5521,9575,2771,1386,5528,2787	CREB3L2,SCN1A,CREB3L4,ATF4,ATF6B,GSK3A,AKT2,GNG7,PPP2R5B,GNAI3,PRKACA,FOS,GNB2,CALM2,CAMK2D,PPP2R5E,PPP2R1A,GNB4,ARNTL,MAPK9,PPP1CB,PPP2R5C,MAOA,GSK3B,GNG13,PPP2R2B,CLOCK,GNAI2,ATF2,PPP2R5D,GNG5
hsa04728	Dopaminergic synapse	0.713733183193919	-0.337246079488899	129	31	0.0173669467787115	1785	6908	64764,6323,148327,468,1388,2931,208,2788,5526,2773,5566,2353,2783,805,817,5529,5518,59345,406,5601,5500,5527,4128,2932,51764,5521,9575,2771,1386,5528,2787	CREB3L2,SCN1A,CREB3L4,ATF4,ATF6B,GSK3A,AKT2,GNG7,PPP2R5B,GNAI3,PRKACA,FOS,GNB2,CALM2,CAMK2D,PPP2R5E,PPP2R1A,GNB4,ARNTL,MAPK9,PPP1CB,PPP2R5C,MAOA,GSK3B,GNG13,PPP2R2B,CLOCK,GNAI2,ATF2,PPP2R5D,GNG5
ko05020	Prion diseases	0.717734901929066	-0.331654995480417	35	8	0.00448179271708683	1785	6908	10963,1958,3569,3309,5604,581,2002,5566	STIP1,EGR1,IL6,HSPA5,MAP2K1,BAX,ELK1,PRKACA
hsa00250	Alanine, aspartate and glutamate metabolism	0.717734901929066	-0.331654995480417	35	8	0.00448179271708683	1785	6908	8659,2744,159,1373,440,57494,5471,2805	ALDH4A1,GLS,ADSS,CPS1,ASNS,RIMKLB,PPAT,GOT1
hsa05020	Prion diseases	0.717734901929066	-0.331654995480417	35	8	0.00448179271708683	1785	6908	10963,1958,3569,3309,5604,581,2002,5566	STIP1,EGR1,IL6,HSPA5,MAP2K1,BAX,ELK1,PRKACA
ko00250	Alanine, aspartate and glutamate metabolism	0.717734901929066	-0.331654995480417	35	8	0.00448179271708683	1785	6908	8659,2744,159,1373,440,57494,5471,2805	ALDH4A1,GLS,ADSS,CPS1,ASNS,RIMKLB,PPAT,GOT1
hsa00511	Other glycan degradation	0.722437117904744	-0.325124896825108	18	4	0.00224089635854342	1785	6908	10825,175,4758,2629	NEU3,AGA,NEU1,GBA
ko00511	Other glycan degradation	0.722437117904744	-0.325124896825108	18	4	0.00224089635854342	1785	6908	10825,175,4758,2629	NEU3,AGA,NEU1,GBA
ko00514	Other types of O-glycan biosynthesis	0.725400726017289	-0.321031051282872	31	7	0.00392156862745098	1785	6908	79709,8985,8705,6480,23275,8704,8473	COLGALT1,PLOD3,B3GALT4,ST6GAL1,POFUT2,B4GALT2,OGT
hsa00514	Other types of O-glycan biosynthesis	0.725400726017289	-0.321031051282872	31	7	0.00392156862745098	1785	6908	79709,8985,8705,6480,23275,8704,8473	COLGALT1,PLOD3,B3GALT4,ST6GAL1,POFUT2,B4GALT2,OGT
hsa02010	ABC transporters	0.735217288917401	-0.307589192279449	44	10	0.00560224089635854	1785	6908	10058,21,10257,5825,89845,20,6890,11194,10347,10351	ABCB6,ABCA3,ABCC4,ABCD3,ABCC10,ABCA2,TAP1,ABCB8,ABCA7,ABCA8
ko02010	ABC transporters	0.735217288917401	-0.307589192279449	44	10	0.00560224089635854	1785	6908	10058,21,10257,5825,89845,20,6890,11194,10347,10351	ABCB6,ABCA3,ABCC4,ABCD3,ABCC10,ABCA2,TAP1,ABCB8,ABCA7,ABCA8
hsa04964	Proximal tubule bicarbonate reclamation	0.747263255358336	-0.291337739121844	23	5	0.00280112044817927	1785	6908	2744,476,483,1468,5105	GLS,ATP1A1,ATP1B3,SLC25A10,PCK1
ko04964	Proximal tubule bicarbonate reclamation	0.747263255358336	-0.291337739121844	23	5	0.00280112044817927	1785	6908	2744,476,483,1468,5105	GLS,ATP1A1,ATP1B3,SLC25A10,PCK1
ko00040	Pentose and glucuronate interconversions	0.7487459443537	-0.289355546123141	36	8	0.00448179271708683	1785	6908	27294,7360,2990,6652,7358,231,224,10327	DHDH,UGP2,GUSB,SORD,UGDH,AKR1B1,ALDH3A2,AKR1A1
hsa00040	Pentose and glucuronate interconversions	0.7487459443537	-0.289355546123141	36	8	0.00448179271708683	1785	6908	27294,231,7360,2990,6652,224,7358,10327	DHDH,AKR1B1,UGP2,GUSB,SORD,ALDH3A2,UGDH,AKR1A1
ko04261	Adrenergic signaling in cardiomyocytes	0.758957998694422	-0.275808840806202	148	35	0.0196078431372549	1785	6908	64764,1388,5526,5566,9252,1390,59283,805,488,5518,783,5296,6548,8503,5521,10411,2771,1386,468,148327,7170,7169,208,11069,7171,154,2773,817,5529,476,5527,5500,784,483,5528	CREB3L2,ATF6B,PPP2R5B,PRKACA,RPS6KA5,CREM,CACNG8,CALM2,ATP2A2,PPP2R1A,CACNB2,PIK3R2,SLC9A1,PIK3R3,PPP2R2B,RAPGEF3,GNAI2,ATF2,ATF4,CREB3L4,TPM3,TPM2,AKT2,RAPGEF4,TPM4,ADRB2,GNAI3,CAMK2D,PPP2R5E,ATP1A1,PPP2R5C,PPP1CB,CACNB3,ATP1B3,PPP2R5D
hsa04261	Adrenergic signaling in cardiomyocytes	0.758957998694422	-0.275808840806202	148	35	0.0196078431372549	1785	6908	64764,1388,5526,5566,9252,1390,59283,805,488,5518,783,5296,6548,8503,5521,10411,2771,1386,468,148327,7170,7169,208,11069,7171,154,2773,817,5529,476,5527,5500,784,483,5528	CREB3L2,ATF6B,PPP2R5B,PRKACA,RPS6KA5,CREM,CACNG8,CALM2,ATP2A2,PPP2R1A,CACNB2,PIK3R2,SLC9A1,PIK3R3,PPP2R2B,RAPGEF3,GNAI2,ATF2,ATF4,CREB3L4,TPM3,TPM2,AKT2,RAPGEF4,TPM4,ADRB2,GNAI3,CAMK2D,PPP2R5E,ATP1A1,PPP2R5C,PPP1CB,CACNB3,ATP1B3,PPP2R5D
ko04921	Oxytocin signaling pathway	0.771530465089008	-0.259379119832818	157	37	0.0207282913165266	1785	6908	5564,5607,4659,5565,5894,8681,5562,5604,1827,5997,5566,140465,59283,595,3725,805,1938,783,5296,54776,8503,4637,5598,2771,9475,5571,3845,2002,2353,2773,817,5743,51422,4660,5500,784,4776	PRKAB1,MAP2K5,PPP1R12A,PRKAB2,RAF1,JMJD7-PLA2G4B,PRKAA1,MAP2K1,RCAN1,RGS2,PRKACA,MYL6B,CACNG8,CCND1,JUN,CALM2,EEF2,CACNB2,PIK3R2,PPP1R12C,PIK3R3,MYL6,MAPK7,GNAI2,ROCK2,PRKAG1,KRAS,ELK1,FOS,GNAI3,CAMK2D,PTGS2,PRKAG2,PPP1R12B,PPP1CB,CACNB3,NFATC4
hsa04921	Oxytocin signaling pathway	0.771530465089008	-0.259379119832818	157	37	0.0207282913165266	1785	6908	5564,5607,4659,5565,5894,8681,5562,5604,1827,5997,5566,140465,59283,595,3725,805,1938,783,5296,54776,8503,4637,5598,2771,9475,5571,3845,2002,2353,2773,817,5743,51422,4660,5500,784,4776	PRKAB1,MAP2K5,PPP1R12A,PRKAB2,RAF1,JMJD7-PLA2G4B,PRKAA1,MAP2K1,RCAN1,RGS2,PRKACA,MYL6B,CACNG8,CCND1,JUN,CALM2,EEF2,CACNB2,PIK3R2,PPP1R12C,PIK3R3,MYL6,MAPK7,GNAI2,ROCK2,PRKAG1,KRAS,ELK1,FOS,GNAI3,CAMK2D,PTGS2,PRKAG2,PPP1R12B,PPP1CB,CACNB3,NFATC4
ko04660	T cell receptor signaling pathway	0.774481075038081	-0.255562054494019	104	24	0.0134453781512605	1785	6908	5058,5170,10451,5609,4690,1019,5894,208,5604,10892,868,3845,1147,2353,3725,8517,998,3551,5601,5296,8503,2932,6885,5970	PAK1,PDPK1,VAV3,MAP2K7,NCK1,CDK4,RAF1,AKT2,MAP2K1,MALT1,CBLB,KRAS,CHUK,FOS,JUN,IKBKG,CDC42,IKBKB,MAPK9,PIK3R2,PIK3R3,GSK3B,MAP3K7,RELA
hsa04660	T cell receptor signaling pathway	0.774481075038081	-0.255562054494019	104	24	0.0134453781512605	1785	6908	5058,5170,10451,5609,4690,1019,5894,208,5604,10892,868,3845,1147,2353,3725,8517,998,3551,5601,5296,8503,2932,6885,5970	PAK1,PDPK1,VAV3,MAP2K7,NCK1,CDK4,RAF1,AKT2,MAP2K1,MALT1,CBLB,KRAS,CHUK,FOS,JUN,IKBKG,CDC42,IKBKB,MAPK9,PIK3R2,PIK3R3,GSK3B,MAP3K7,RELA
ko00232	Caffeine metabolism	0.775797231096018	-0.253864093077743	5	1	0.000560224089635854	1785	6908	9	NAT1
hsa00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.775797231096018	-0.253864093077743	5	1	0.000560224089635854	1785	6908	2805	GOT1
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.775797231096018	-0.253864093077743	5	1	0.000560224089635854	1785	6908	2805	GOT1
hsa00232	Caffeine metabolism	0.775797231096018	-0.253864093077743	5	1	0.000560224089635854	1785	6908	9	NAT1
hsa05330	Allograft rejection	0.77728778030178	-0.251944623567103	37	8	0.00448179271708683	1785	6908	3122,3108,3592,3107,3134,3133,3105,3109	HLA-DRA,HLA-DMA,IL12A,HLA-C,HLA-F,HLA-E,HLA-A,HLA-DMB
ko05330	Allograft rejection	0.77728778030178	-0.251944623567103	37	8	0.00448179271708683	1785	6908	3122,3108,3592,3107,3134,3133,3105,3109	HLA-DRA,HLA-DMA,IL12A,HLA-C,HLA-F,HLA-E,HLA-A,HLA-DMB
hsa04977	Vitamin digestion and absorption	0.782121787318311	-0.245744812304061	24	5	0.00280112044817927	1785	6908	55788,25974,8884,10560,686	LMBRD1,MMACHC,SLC5A6,SLC19A2,BTD
ko04977	Vitamin digestion and absorption	0.782121787318311	-0.245744812304061	24	5	0.00280112044817927	1785	6908	55788,25974,8884,10560,686	LMBRD1,MMACHC,SLC5A6,SLC19A2,BTD
ko00010	Glycolysis / Gluconeogenesis	0.782309339513703	-0.245505041830214	67	15	0.00840336134453781	1785	6908	5160,221,2597,5230,669,226,3939,5105,5224,501,83440,92579,1738,224,10327	PDHA1,ALDH3B1,GAPDH,PGK1,BPGM,ALDOA,LDHA,PCK1,PGAM2,ALDH7A1,ADPGK,G6PC3,DLD,ALDH3A2,AKR1A1
hsa00010	Glycolysis / Gluconeogenesis	0.782309339513703	-0.245505041830214	67	15	0.00840336134453781	1785	6908	5160,221,2597,669,5230,226,5105,3939,501,5224,83440,92579,1738,224,10327	PDHA1,ALDH3B1,GAPDH,BPGM,PGK1,ALDOA,PCK1,LDHA,ALDH7A1,PGAM2,ADPGK,G6PC3,DLD,ALDH3A2,AKR1A1
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.78613854995933	-0.240622229874163	15	3	0.00168067226890756	1785	6908	6483,10678,8704	ST3GAL2,B3GNT2,B4GALT2
hsa00604	Glycosphingolipid biosynthesis - ganglio series	0.78613854995933	-0.240622229874163	15	3	0.00168067226890756	1785	6908	6483,8705,9197	ST3GAL2,B3GALT4,SLC33A1
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.78613854995933	-0.240622229874163	15	3	0.00168067226890756	1785	6908	6483,10678,8704	ST3GAL2,B3GNT2,B4GALT2
ko00604	Glycosphingolipid biosynthesis - ganglio series	0.78613854995933	-0.240622229874163	15	3	0.00168067226890756	1785	6908	6483,8705,9197	ST3GAL2,B3GALT4,SLC33A1
ko04350	TGF-beta signaling pathway	0.787156300616774	-0.239328447212843	84	19	0.0106442577030812	1785	6908	1030,4052,7050,3397,659,1875,4092,3398,654,5308,9765,5518,5933,4609,9241,6198,4091,6667,6199	CDKN2B,LTBP1,TGIF1,ID1,BMPR2,E2F5,SMAD7,ID2,BMP6,PITX2,ZFYVE16,PPP2R1A,RBL1,MYC,NOG,RPS6KB1,SMAD6,SP1,RPS6KB2
hsa04350	TGF-beta signaling pathway	0.787156300616774	-0.239328447212843	84	19	0.0106442577030812	1785	6908	1030,4052,7050,3397,659,1875,4092,3398,654,5308,9765,5518,5933,4609,9241,6198,4091,6667,6199	CDKN2B,LTBP1,TGIF1,ID1,BMPR2,E2F5,SMAD7,ID2,BMP6,PITX2,ZFYVE16,PPP2R1A,RBL1,MYC,NOG,RPS6KB1,SMAD6,SP1,RPS6KB2
hsa05205	Proteoglycans in cancer	0.788694406121362	-0.237376351133632	203	48	0.026890756302521	1785	6908	673,2335,4659,967,2475,5894,5604,7157,2535,6382,5566,595,998,1499,80326,4609,5296,9138,54776,6194,5781,8503,6548,2017,2065,4233,6774,9475,6199,8321,5058,5170,6237,1975,84309,208,868,3845,23365,857,2002,817,369,10855,3688,5500,4660,6198	BRAF,FN1,PPP1R12A,CD63,MTOR,RAF1,MAP2K1,TP53,FZD2,SDC1,PRKACA,CCND1,CDC42,CTNNB1,WNT10A,MYC,PIK3R2,ARHGEF1,PPP1R12C,RPS6,PTPN11,PIK3R3,SLC9A1,CTTN,ERBB3,MET,STAT3,ROCK2,RPS6KB2,FZD1,PAK1,PDPK1,RRAS,EIF4B,NUDT16L1,AKT2,CBLB,KRAS,ARHGEF12,CAV1,ELK1,CAMK2D,ARAF,HPSE,ITGB1,PPP1CB,PPP1R12B,RPS6KB1
ko05205	Proteoglycans in cancer	0.788694406121362	-0.237376351133632	203	48	0.026890756302521	1785	6908	673,2335,4659,967,2475,5894,5604,7157,2535,6382,5566,595,998,1499,80326,4609,5296,9138,54776,6194,5781,8503,6548,2017,2065,4233,6774,9475,6199,8321,5058,5170,6237,1975,84309,208,868,3845,23365,857,2002,817,369,10855,3688,5500,4660,6198	BRAF,FN1,PPP1R12A,CD63,MTOR,RAF1,MAP2K1,TP53,FZD2,SDC1,PRKACA,CCND1,CDC42,CTNNB1,WNT10A,MYC,PIK3R2,ARHGEF1,PPP1R12C,RPS6,PTPN11,PIK3R3,SLC9A1,CTTN,ERBB3,MET,STAT3,ROCK2,RPS6KB2,FZD1,PAK1,PDPK1,RRAS,EIF4B,NUDT16L1,AKT2,CBLB,KRAS,ARHGEF12,CAV1,ELK1,CAMK2D,ARAF,HPSE,ITGB1,PPP1CB,PPP1R12B,RPS6KB1
ko00860	Porphyrin and chlorophyll metabolism	0.794646498140642	-0.229857919643655	42	9	0.00504201680672269	1785	6908	2058,124454,210,2990,645,3145,3163,5498,326625	EPRS,EARS2,ALAD,GUSB,BLVRB,HMBS,HMOX2,PPOX,MMAB
hsa00860	Porphyrin and chlorophyll metabolism	0.794646498140642	-0.229857919643655	42	9	0.00504201680672269	1785	6908	2058,124454,210,2990,645,3145,3163,5498,326625	EPRS,EARS2,ALAD,GUSB,BLVRB,HMBS,HMOX2,PPOX,MMAB
hsa04662	B cell receptor signaling pathway	0.797782949182176	-0.225918712035316	72	16	0.00896358543417367	1785	6908	10451,3636,5894,208,5604,10892,3845,1147,2353,3725,8517,5296,3551,2932,8503,5970	VAV3,INPPL1,RAF1,AKT2,MAP2K1,MALT1,KRAS,CHUK,FOS,JUN,IKBKG,PIK3R2,IKBKB,GSK3B,PIK3R3,RELA
ko04662	B cell receptor signaling pathway	0.797782949182176	-0.225918712035316	72	16	0.00896358543417367	1785	6908	10451,3636,5894,208,5604,10892,3845,1147,2353,3725,8517,5296,3551,2932,8503,5970	VAV3,INPPL1,RAF1,AKT2,MAP2K1,MALT1,KRAS,CHUK,FOS,JUN,IKBKG,PIK3R2,IKBKB,GSK3B,PIK3R3,RELA
ko00030	Pentose phosphate pathway	0.798724286263969	-0.224739466279356	29	6	0.00336134453781513	1785	6908	64080,25796,5631,226,5226,22934	RBKS,PGLS,PRPS1,ALDOA,PGD,RPIA
ko00760	Nicotinate and nicotinamide metabolism	0.798724286263969	-0.224739466279356	29	6	0.00336134453781513	1785	6908	133686,55191,30833,4837,93100,65220	NADK2,NADSYN1,NT5C,NNMT,NAPRT,NADK
hsa00030	Pentose phosphate pathway	0.798724286263969	-0.224739466279356	29	6	0.00336134453781513	1785	6908	64080,25796,5631,226,22934,5226	RBKS,PGLS,PRPS1,ALDOA,RPIA,PGD
hsa00760	Nicotinate and nicotinamide metabolism	0.798724286263969	-0.224739466279356	29	6	0.00336134453781513	1785	6908	133686,55191,30833,4837,93100,65220	NADK2,NADSYN1,NT5C,NNMT,NAPRT,NADK
ko00220	Arginine biosynthesis	0.799718821034589	-0.223495086802333	20	4	0.00224089635854342	1785	6908	2744,384,2805,1373	GLS,ARG2,GOT1,CPS1
hsa00220	Arginine biosynthesis	0.799718821034589	-0.223495086802333	20	4	0.00224089635854342	1785	6908	2744,384,2805,1373	GLS,ARG2,GOT1,CPS1
hsa04340	Hedgehog signaling pathway	0.803178341547207	-0.21917849561341	51	11	0.0061624649859944	1785	6908	1455,23291,53944,80326,1454,2932,1452,5566,8945,1456,2735	CSNK1G2,FBXW11,CSNK1G1,WNT10A,CSNK1E,GSK3B,CSNK1A1,PRKACA,BTRC,CSNK1G3,GLI1
ko04340	Hedgehog signaling pathway	0.803178341547207	-0.21917849561341	51	11	0.0061624649859944	1785	6908	1455,23291,53944,80326,1454,2932,1452,5566,8945,1456,2735	CSNK1G2,FBXW11,CSNK1G1,WNT10A,CSNK1E,GSK3B,CSNK1A1,PRKACA,BTRC,CSNK1G3,GLI1
ko04961	Endocrine and other factor-regulated calcium reabsorption	0.810121614877459	-0.210570900761785	47	10	0.00560224089635854	1785	6908	7421,476,160,1213,1785,163,483,5566,8766,1175	VDR,ATP1A1,AP2A1,CLTC,DNM2,AP2B1,ATP1B3,PRKACA,RAB11A,AP2S1
hsa04961	Endocrine and other factor-regulated calcium reabsorption	0.810121614877459	-0.210570900761785	47	10	0.00560224089635854	1785	6908	7421,476,160,1213,1785,163,483,5566,8766,1175	VDR,ATP1A1,AP2A1,CLTC,DNM2,AP2B1,ATP1B3,PRKACA,RAB11A,AP2S1
hsa04070	Phosphatidylinositol signaling system	0.811832633670656	-0.208461076234459	98	22	0.0123249299719888	1785	6908	5289,3636,9807,90809,8527,3633,51447,8394,8867,1040,55361,805,51763,8396,64768,5298,9110,5296,253430,8503,200576,3613	PIK3C3,INPPL1,IP6K1,TMEM55B,DGKD,INPP5B,IP6K2,PIP5K1A,SYNJ1,CDS1,PI4K2A,CALM2,INPP5K,PIP4K2B,IPPK,PI4KB,MTMR4,PIK3R2,IPMK,PIK3R3,PIKFYVE,IMPA2
ko04070	Phosphatidylinositol signaling system	0.811832633670656	-0.208461076234459	98	22	0.0123249299719888	1785	6908	5289,3636,9807,90809,8527,3633,51447,8394,8867,1040,55361,805,51763,8396,64768,5298,9110,5296,253430,8503,200576,3613	PIK3C3,INPPL1,IP6K1,TMEM55B,DGKD,INPP5B,IP6K2,PIP5K1A,SYNJ1,CDS1,PI4K2A,CALM2,INPP5K,PIP4K2B,IPPK,PI4KB,MTMR4,PIK3R2,IPMK,PIK3R3,PIKFYVE,IMPA2
ko00592	alpha-Linolenic acid metabolism	0.813135955892773	-0.206856955994888	25	5	0.00280112044817927	1785	6908	9415,81579,8310,51,8681	FADS2,PLA2G12A,ACOX3,ACOX1,JMJD7-PLA2G4B
hsa00592	alpha-Linolenic acid metabolism	0.813135955892773	-0.206856955994888	25	5	0.00280112044817927	1785	6908	9415,81579,8310,8681,51	FADS2,PLA2G12A,ACOX3,JMJD7-PLA2G4B,ACOX1
ko04370	VEGF signaling pathway	0.830685212851999	-0.185504361123766	61	13	0.00728291316526611	1785	6908	572,5743,998,7867,8681,5894,208,5296,842,5604,8503,3845,56848	BAD,PTGS2,CDC42,MAPKAPK3,JMJD7-PLA2G4B,RAF1,AKT2,PIK3R2,CASP9,MAP2K1,PIK3R3,KRAS,SPHK2
hsa04370	VEGF signaling pathway	0.830685212851999	-0.185504361123766	61	13	0.00728291316526611	1785	6908	572,5743,998,7867,8681,5894,208,5296,842,5604,8503,3845,56848	BAD,PTGS2,CDC42,MAPKAPK3,JMJD7-PLA2G4B,RAF1,AKT2,PIK3R2,CASP9,MAP2K1,PIK3R3,KRAS,SPHK2
ko05110	Vibrio cholerae infection	0.843164082849463	-0.170593698343434	53	11	0.0061624649859944	1785	6908	51382,523,23480,23545,535,7082,51606,528,5566,529,9114	ATP6V1D,ATP6V1A,SEC61G,ATP6V0A2,ATP6V0A1,TJP1,ATP6V1H,ATP6V1C1,PRKACA,ATP6V1E1,ATP6V0D1
hsa05110	Vibrio cholerae infection	0.843164082849463	-0.170593698343434	53	11	0.0061624649859944	1785	6908	51382,523,23480,23545,535,7082,51606,528,5566,529,9114	ATP6V1D,ATP6V1A,SEC61G,ATP6V0A2,ATP6V0A1,TJP1,ATP6V1H,ATP6V1C1,PRKACA,ATP6V1E1,ATP6V0D1
hsa04530	Tight junction	0.844729826350521	-0.16873843487974	138	31	0.0173669467787115	1785	6908	55870,6237,1495,1019,208,4627,3845,50848,87,1460,7082,4628,2773,10627,260425,93643,2035,5581,998,27134,1499,3993,5518,60412,5584,2017,5521,9223,1365,2771,6709	ASH1L,RRAS,CTNNA1,CDK4,AKT2,MYH9,KRAS,F11R,ACTN1,CSNK2B,TJP1,MYH10,GNAI3,MYL12A,MAGI3,TJAP1,EPB41,PRKCE,CDC42,TJP3,CTNNB1,LLGL2,PPP2R1A,EXOC4,PRKCI,CTTN,PPP2R2B,MAGI1,CLDN3,GNAI2,SPTAN1
ko04530	Tight junction	0.844729826350521	-0.16873843487974	138	31	0.0173669467787115	1785	6908	55870,6237,1495,1019,208,4627,3845,50848,87,1460,7082,4628,2773,10627,260425,93643,2035,5581,998,27134,1499,3993,5518,60412,5584,2017,5521,9223,1365,2771,6709	ASH1L,RRAS,CTNNA1,CDK4,AKT2,MYH9,KRAS,F11R,ACTN1,CSNK2B,TJP1,MYH10,GNAI3,MYL12A,MAGI3,TJAP1,EPB41,PRKCE,CDC42,TJP3,CTNNB1,LLGL2,PPP2R1A,EXOC4,PRKCI,CTTN,PPP2R2B,MAGI1,CLDN3,GNAI2,SPTAN1
ko00410	beta-Alanine metabolism	0.849912536143233	-0.162621833447225	31	6	0.00336134453781513	1785	6908	501,221,55748,4329,224,6611	ALDH7A1,ALDH3B1,CNDP2,ALDH6A1,ALDH3A2,SMS
hsa00410	beta-Alanine metabolism	0.849912536143233	-0.162621833447225	31	6	0.00336134453781513	1785	6908	501,221,55748,4329,224,6611	ALDH7A1,ALDH3B1,CNDP2,ALDH6A1,ALDH3A2,SMS
hsa04918	Thyroid hormone synthesis	0.853401915444211	-0.158524663744922	71	15	0.00840336134453781	1785	6908	64764,476,148327,468,7184,1388,1081,3309,8458,483,821,1386,5566,7270,493869	CREB3L2,ATP1A1,CREB3L4,ATF4,HSP90B1,ATF6B,CGA,HSPA5,TTF2,ATP1B3,CANX,ATF2,PRKACA,TTF1,GPX8
ko04918	Thyroid hormone synthesis	0.853401915444211	-0.158524663744922	71	15	0.00840336134453781	1785	6908	64764,476,148327,468,7184,1388,1081,3309,8458,483,821,1386,5566,7270,493869	CREB3L2,ATP1A1,CREB3L4,ATF4,HSP90B1,ATF6B,CGA,HSPA5,TTF2,ATP1B3,CANX,ATF2,PRKACA,TTF1,GPX8
ko00120	Primary bile acid biosynthesis	0.854851180057591	-0.156827883607475	17	3	0.00168067226890756	1785	6908	3295,10858,10005	HSD17B4,CYP46A1,ACOT8
hsa00120	Primary bile acid biosynthesis	0.854851180057591	-0.156827883607475	17	3	0.00168067226890756	1785	6908	3295,10858,10005	HSD17B4,CYP46A1,ACOT8
hsa05031	Amphetamine addiction	0.858477050791559	-0.152595330753148	67	14	0.00784313725490196	1785	6908	64764,23411,3725,805,817,148327,468,1388,2354,5500,4128,1386,5566,2353	CREB3L2,SIRT1,JUN,CALM2,CAMK2D,CREB3L4,ATF4,ATF6B,FOSB,PPP1CB,MAOA,ATF2,PRKACA,FOS
ko05031	Amphetamine addiction	0.858477050791559	-0.152595330753148	67	14	0.00784313725490196	1785	6908	64764,23411,3725,805,817,148327,468,1388,2354,5500,4128,1386,5566,2353	CREB3L2,SIRT1,JUN,CALM2,CAMK2D,CREB3L4,ATF4,ATF6B,FOSB,PPP1CB,MAOA,ATF2,PRKACA,FOS
ko05152	Tuberculosis	0.861606905599134	-0.148956138317001	177	40	0.0224089635854342	1785	6908	3122,5894,54205,8411,805,3592,5601,581,23545,3717,51606,3459,5970,9114,1263,3920,5289,8767,7879,208,842,3109,10892,535,5868,23365,5869,3587,8772,7421,572,3108,817,3313,3569,4802,6772,1054,56848,5878	HLA-DRA,RAF1,CYCS,EEA1,CALM2,IL12A,MAPK9,BAX,ATP6V0A2,JAK2,ATP6V1H,IFNGR1,RELA,ATP6V0D1,PLK3,LAMP2,PIK3C3,RIPK2,RAB7A,AKT2,CASP9,HLA-DMB,MALT1,ATP6V0A1,RAB5A,ARHGEF12,RAB5B,IL10RA,FADD,VDR,BAD,HLA-DMA,CAMK2D,HSPA9,IL6,NFYC,STAT1,CEBPG,SPHK2,RAB5C
hsa05152	Tuberculosis	0.861606905599134	-0.148956138317001	177	40	0.0224089635854342	1785	6908	3122,5894,54205,8411,805,3592,5601,581,23545,3717,51606,3459,5970,9114,1263,3920,5289,8767,7879,208,842,3109,10892,535,5868,23365,5869,3587,8772,7421,572,3108,817,3313,3569,4802,6772,1054,56848,5878	HLA-DRA,RAF1,CYCS,EEA1,CALM2,IL12A,MAPK9,BAX,ATP6V0A2,JAK2,ATP6V1H,IFNGR1,RELA,ATP6V0D1,PLK3,LAMP2,PIK3C3,RIPK2,RAB7A,AKT2,CASP9,HLA-DMB,MALT1,ATP6V0A1,RAB5A,ARHGEF12,RAB5B,IL10RA,FADD,VDR,BAD,HLA-DMA,CAMK2D,HSPA9,IL6,NFYC,STAT1,CEBPG,SPHK2,RAB5C
ko05332	Graft-versus-host disease	0.867779463416228	-0.141817671009424	41	8	0.00448179271708683	1785	6908	3122,3108,3107,3134,3569,3133,3105,3109	HLA-DRA,HLA-DMA,HLA-C,HLA-F,IL6,HLA-E,HLA-A,HLA-DMB
hsa05332	Graft-versus-host disease	0.867779463416228	-0.141817671009424	41	8	0.00448179271708683	1785	6908	3122,3108,3107,3134,3569,3133,3105,3109	HLA-DRA,HLA-DMA,HLA-C,HLA-F,IL6,HLA-E,HLA-A,HLA-DMB
hsa05140	Leishmaniasis	0.868038485503331	-0.141519227167216	72	15	0.00840336134453781	1785	6908	3122,3108,3725,3592,5743,6772,3688,3109,3717,6885,3459,2002,10454,5970,2353	HLA-DRA,HLA-DMA,JUN,IL12A,PTGS2,STAT1,ITGB1,HLA-DMB,JAK2,MAP3K7,IFNGR1,ELK1,TAB1,RELA,FOS
ko05140	Leishmaniasis	0.868038485503331	-0.141519227167216	72	15	0.00840336134453781	1785	6908	3122,3108,3725,3592,5743,6772,3688,3109,3717,6885,3459,2002,10454,5970,2353	HLA-DRA,HLA-DMA,JUN,IL12A,PTGS2,STAT1,ITGB1,HLA-DMB,JAK2,MAP3K7,IFNGR1,ELK1,TAB1,RELA,FOS
hsa00983	Drug metabolism - other enzymes	0.876005469740651	-0.132382944069062	46	9	0.00504201680672269	1785	6908	1890,7083,2990,9,54963,7378,3614,7372,3615	TYMP,TK1,GUSB,NAT1,UCKL1,UPP1,IMPDH1,UMPS,IMPDH2
ko00983	Drug metabolism - other enzymes	0.876005469740651	-0.132382944069062	46	9	0.00504201680672269	1785	6908	1890,7083,2990,9,54963,7378,3614,7372,3615	TYMP,TK1,GUSB,NAT1,UCKL1,UPP1,IMPDH1,UMPS,IMPDH2
hsa00460	Cyanoamino acid metabolism	0.876762226911815	-0.131519444337032	7	1	0.000560224089635854	1785	6908	6470	SHMT1
ko00460	Cyanoamino acid metabolism	0.876762226911815	-0.131519444337032	7	1	0.000560224089635854	1785	6908	6470	SHMT1
ko05160	Hepatitis C	0.881053599609239	-0.126636815385551	133	29	0.0162464985994398	1785	6908	5170,673,208,5894,7186,9451,7157,1147,3845,440275,10062,7297,6773,572,8517,369,5518,3551,5296,5601,6772,10379,2932,8503,5521,10197,1365,5970,6774	PDPK1,BRAF,AKT2,RAF1,TRAF2,EIF2AK3,TP53,CHUK,KRAS,EIF2AK4,NR1H3,TYK2,STAT2,BAD,IKBKG,ARAF,PPP2R1A,IKBKB,PIK3R2,MAPK9,STAT1,IRF9,GSK3B,PIK3R3,PPP2R2B,PSME3,CLDN3,RELA,STAT3
hsa05160	Hepatitis C	0.881053599609239	-0.126636815385551	133	29	0.0162464985994398	1785	6908	5170,673,208,5894,7186,9451,7157,1147,3845,440275,10062,7297,6773,572,8517,369,5518,3551,5296,5601,6772,10379,2932,8503,5521,10197,1365,5970,6774	PDPK1,BRAF,AKT2,RAF1,TRAF2,EIF2AK3,TP53,CHUK,KRAS,EIF2AK4,NR1H3,TYK2,STAT2,BAD,IKBKG,ARAF,PPP2R1A,IKBKB,PIK3R2,MAPK9,STAT1,IRF9,GSK3B,PIK3R3,PPP2R2B,PSME3,CLDN3,RELA,STAT3
hsa04978	Mineral absorption	0.883725840057851	-0.123608400127674	51	10	0.00560224089635854	1785	6908	7421,2512,1317,476,4502,4891,4501,483,3163,7779	VDR,FTL,SLC31A1,ATP1A1,MT2A,SLC11A2,MT1X,ATP1B3,HMOX2,SLC30A1
ko04978	Mineral absorption	0.883725840057851	-0.123608400127674	51	10	0.00560224089635854	1785	6908	7421,2512,1317,476,4502,4891,4501,483,3163,7779	VDR,FTL,SLC31A1,ATP1A1,MT2A,SLC11A2,MT1X,ATP1B3,HMOX2,SLC30A1
ko00640	Propanoate metabolism	0.8853635130625	-0.121756969085413	28	5	0.00280112044817927	1785	6908	8802,4329,4594,55862,3939	SUCLG1,ALDH6A1,MUT,ECHDC1,LDHA
hsa00640	Propanoate metabolism	0.8853635130625	-0.121756969085413	28	5	0.00280112044817927	1785	6908	8802,4329,4594,55862,3939	SUCLG1,ALDH6A1,MUT,ECHDC1,LDHA
hsa00061	Fatty acid biosynthesis	0.886746573870031	-0.120196049029097	13	2	0.00112044817927171	1785	6908	27349,54995	MCAT,OXSM
ko00061	Fatty acid biosynthesis	0.886746573870031	-0.120196049029097	13	2	0.00112044817927171	1785	6908	27349,54995	MCAT,OXSM
ko04912	GnRH signaling pathway	0.888608872529617	-0.118098103689285	91	19	0.0106442577030812	1785	6908	4215,468,5609,1081,8681,5894,5604,3845,2002,5566,5606,805,3725,817,998,5608,5601,2185,5598	MAP3K3,ATF4,MAP2K7,CGA,JMJD7-PLA2G4B,RAF1,MAP2K1,KRAS,ELK1,PRKACA,MAP2K3,CALM2,JUN,CAMK2D,CDC42,MAP2K6,MAPK9,PTK2B,MAPK7
hsa04912	GnRH signaling pathway	0.888608872529617	-0.118098103689285	91	19	0.0106442577030812	1785	6908	4215,468,5609,1081,8681,5894,5604,3845,2002,5566,5606,805,3725,817,998,5608,5601,2185,5598	MAP3K3,ATF4,MAP2K7,CGA,JMJD7-PLA2G4B,RAF1,MAP2K1,KRAS,ELK1,PRKACA,MAP2K3,CALM2,JUN,CAMK2D,CDC42,MAP2K6,MAPK9,PTK2B,MAPK7
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.893849289449986	-0.112218098053407	74	15	0.00840336134453781	1785	6908	59283,1499,488,2010,3728,1495,783,3688,5318,87,784,1832,1605,6934,4000	CACNG8,CTNNB1,ATP2A2,EMD,JUP,CTNNA1,CACNB2,ITGB1,PKP2,ACTN1,CACNB3,DSP,DAG1,TCF7L2,LMNA
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.893849289449986	-0.112218098053407	74	15	0.00840336134453781	1785	6908	59283,1499,488,2010,3728,1495,783,3688,5318,87,784,1832,1605,6934,4000	CACNG8,CTNNB1,ATP2A2,EMD,JUP,CTNNA1,CACNB2,ITGB1,PKP2,ACTN1,CACNB3,DSP,DAG1,TCF7L2,LMNA
ko05410	Hypertrophic cardiomyopathy (HCM)	0.896391435369884	-0.109378091574589	83	17	0.00952380952380952	1785	6908	5564,7169,7170,5565,5562,7171,5571,1605,4000,59283,51422,2010,488,783,3569,3688,784	PRKAB1,TPM2,TPM3,PRKAB2,PRKAA1,TPM4,PRKAG1,DAG1,LMNA,CACNG8,PRKAG2,EMD,ATP2A2,CACNB2,IL6,ITGB1,CACNB3
hsa05410	Hypertrophic cardiomyopathy (HCM)	0.896391435369884	-0.109378091574589	83	17	0.00952380952380952	1785	6908	5564,7169,7170,5565,5562,7171,5571,1605,4000,59283,51422,2010,488,783,3569,3688,784	PRKAB1,TPM2,TPM3,PRKAB2,PRKAA1,TPM4,PRKAG1,DAG1,LMNA,CACNG8,PRKAG2,EMD,ATP2A2,CACNB2,IL6,ITGB1,CACNB3
hsa04664	Fc epsilon RI signaling pathway	0.898765027590574	-0.106733649540827	70	14	0.00784313725490196	1785	6908	5170,5581,10451,5609,5608,8681,5894,208,5296,5601,5604,8503,3845,5606	PDPK1,PRKCE,VAV3,MAP2K7,MAP2K6,JMJD7-PLA2G4B,RAF1,AKT2,PIK3R2,MAPK9,MAP2K1,PIK3R3,KRAS,MAP2K3
ko04664	Fc epsilon RI signaling pathway	0.898765027590574	-0.106733649540827	70	14	0.00784313725490196	1785	6908	5170,5581,10451,5609,5608,8681,5894,208,5296,5601,5604,8503,3845,5606	PDPK1,PRKCE,VAV3,MAP2K7,MAP2K6,JMJD7-PLA2G4B,RAF1,AKT2,PIK3R2,MAPK9,MAP2K1,PIK3R3,KRAS,MAP2K3
ko04930	Type II diabetes mellitus	0.905546714029687	-0.0992164137793111	48	9	0.00504201680672269	1785	6908	5581,6517,8651,2475,3551,5296,5601,122809,8503	PRKCE,SLC2A4,SOCS1,MTOR,IKBKB,PIK3R2,MAPK9,SOCS4,PIK3R3
hsa04930	Type II diabetes mellitus	0.905546714029687	-0.0992164137793111	48	9	0.00504201680672269	1785	6908	5581,6517,8651,2475,3551,5296,5601,122809,8503	PRKCE,SLC2A4,SOCS1,MTOR,IKBKB,PIK3R2,MAPK9,SOCS4,PIK3R3
ko00071	Fatty acid degradation	0.913841230753547	-0.0900984307640983	44	8	0.00448179271708683	1785	6908	3033,51,3032,501,2639,1632,224,8310	HADH,ACOX1,HADHB,ALDH7A1,GCDH,ECI1,ALDH3A2,ACOX3
hsa00071	Fatty acid degradation	0.913841230753547	-0.0900984307640983	44	8	0.00448179271708683	1785	6908	3033,51,3032,501,2639,1632,224,8310	HADH,ACOX1,HADHB,ALDH7A1,GCDH,ECI1,ALDH3A2,ACOX3
ko00052	Galactose metabolism	0.918933327152382	-0.084541708602805	30	5	0.00280112044817927	1785	6908	231,92579,7360,8704,2582	AKR1B1,G6PC3,UGP2,B4GALT2,GALE
hsa00052	Galactose metabolism	0.918933327152382	-0.084541708602805	30	5	0.00280112044817927	1785	6908	231,92579,7360,8704,2582	AKR1B1,G6PC3,UGP2,B4GALT2,GALE
ko00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.921722067514946	-0.0815115460808394	20	3	0.00168067226890756	1785	6908	337876,50515,26229	CHSY3,CHST11,B3GAT3
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.921722067514946	-0.0815115460808394	20	3	0.00168067226890756	1785	6908	337876,50515,26229	CHSY3,CHST11,B3GAT3
ko04973	Carbohydrate digestion and absorption	0.925782268793663	-0.0771162028759326	45	8	0.00448179271708683	1785	6908	8503,476,483,92579,2542,208,5296,83756	PIK3R3,ATP1A1,ATP1B3,G6PC3,SLC37A4,AKT2,PIK3R2,TAS1R3
hsa04973	Carbohydrate digestion and absorption	0.925782268793663	-0.0771162028759326	45	8	0.00448179271708683	1785	6908	8503,476,483,92579,2542,208,5296,83756	PIK3R3,ATP1A1,ATP1B3,G6PC3,SLC37A4,AKT2,PIK3R2,TAS1R3
ko05217	Basal cell carcinoma	0.932160194371233	-0.0702505966940608	55	10	0.00560224089635854	1785	6908	1499,80326,7157,2932,324,2535,1856,6934,2735,8321	CTNNB1,WNT10A,TP53,GSK3B,APC,FZD2,DVL2,TCF7L2,GLI1,FZD1
hsa05217	Basal cell carcinoma	0.932160194371233	-0.0702505966940608	55	10	0.00560224089635854	1785	6908	1499,80326,7157,2932,324,2535,1856,6934,2735,8321	CTNNB1,WNT10A,TP53,GSK3B,APC,FZD2,DVL2,TCF7L2,GLI1,FZD1
ko00512	Mucin type O-Glycan biosynthesis	0.932206556197431	-0.0702008620308635	31	5	0.00280112044817927	1785	6908	29071,56913,6483,63917,55568	C1GALT1C1,C1GALT1,ST3GAL2,GALNT11,GALNT10
hsa00512	Mucin type O-Glycan biosynthesis	0.932206556197431	-0.0702008620308635	31	5	0.00280112044817927	1785	6908	29071,56913,6483,63917,55568	C1GALT1C1,C1GALT1,ST3GAL2,GALNT11,GALNT10
ko03320	PPAR signaling pathway	0.933775519777644	-0.0685192124907542	69	13	0.00728291316526611	1785	6908	5170,5467,2710,9415,4973,51,79966,1622,5105,10062,8310,7316,6257	PDPK1,PPARD,GK,FADS2,OLR1,ACOX1,SCD5,DBI,PCK1,NR1H3,ACOX3,UBC,RXRB
hsa03320	PPAR signaling pathway	0.933775519777644	-0.0685192124907542	69	13	0.00728291316526611	1785	6908	5170,5467,2710,9415,4973,79966,51,1622,5105,10062,8310,7316,6257	PDPK1,PPARD,GK,FADS2,OLR1,SCD5,ACOX1,DBI,PCK1,NR1H3,ACOX3,UBC,RXRB
hsa04151	PI3K-Akt signaling pathway	0.934809955223436	-0.067412026798364	346	78	0.0436974789915966	1785	6908	64764,2475,5894,5604,7157,1147,5526,598,7531,2783,595,5518,3551,5296,6194,1027,2997,8503,5521,4233,1386,5970,1977,1021,2787,11140,64223,468,208,3326,1019,842,2788,10971,6009,7532,572,5529,8517,1969,59345,3688,2932,5527,6198,5528,284,7184,9170,2335,1388,5562,23239,54541,3914,5586,4609,23678,5105,6446,3717,51764,3320,6199,5170,148327,1975,3164,3845,92579,200186,7248,3569,9180,7534,1942,7533,1288	CREB3L2,MTOR,RAF1,MAP2K1,TP53,CHUK,PPP2R5B,BCL2L1,YWHAE,GNB2,CCND1,PPP2R1A,IKBKB,PIK3R2,RPS6,CDKN1B,GYS1,PIK3R3,PPP2R2B,MET,ATF2,RELA,EIF4E,CDK6,GNG5,CDC37,MLST8,ATF4,AKT2,HSP90AB1,CDK4,CASP9,GNG7,YWHAQ,RHEB,YWHAG,BAD,PPP2R5E,IKBKG,EPHA2,GNB4,ITGB1,GSK3B,PPP2R5C,RPS6KB1,PPP2R5D,ANGPT1,HSP90B1,LPAR2,FN1,ATF6B,PRKAA1,PHLPP1,DDIT4,LAMB3,PKN2,MYC,SGK3,PCK1,SGK1,JAK2,GNG13,HSP90AA1,RPS6KB2,PDPK1,CREB3L4,EIF4B,NR4A1,KRAS,G6PC3,CRTC2,TSC1,IL6,OSMR,YWHAZ,EFNA1,YWHAH,COL4A6
ko04151	PI3K-Akt signaling pathway	0.934809955223436	-0.067412026798364	346	78	0.0436974789915966	1785	6908	64764,2475,5894,5604,7157,1147,5526,598,7531,2783,595,5518,3551,5296,6194,1027,2997,8503,5521,4233,1386,5970,1977,1021,2787,11140,64223,468,208,3326,1019,842,2788,10971,6009,7532,572,5529,8517,1969,59345,3688,2932,5527,6198,5528,284,7184,9170,2335,1388,5562,23239,54541,3914,5586,4609,23678,5105,6446,3717,51764,3320,6199,5170,148327,1975,3164,3845,92579,200186,7248,3569,9180,7534,1942,7533,1288	CREB3L2,MTOR,RAF1,MAP2K1,TP53,CHUK,PPP2R5B,BCL2L1,YWHAE,GNB2,CCND1,PPP2R1A,IKBKB,PIK3R2,RPS6,CDKN1B,GYS1,PIK3R3,PPP2R2B,MET,ATF2,RELA,EIF4E,CDK6,GNG5,CDC37,MLST8,ATF4,AKT2,HSP90AB1,CDK4,CASP9,GNG7,YWHAQ,RHEB,YWHAG,BAD,PPP2R5E,IKBKG,EPHA2,GNB4,ITGB1,GSK3B,PPP2R5C,RPS6KB1,PPP2R5D,ANGPT1,HSP90B1,LPAR2,FN1,ATF6B,PRKAA1,PHLPP1,DDIT4,LAMB3,PKN2,MYC,SGK3,PCK1,SGK1,JAK2,GNG13,HSP90AA1,RPS6KB2,PDPK1,CREB3L4,EIF4B,NR4A1,KRAS,G6PC3,CRTC2,TSC1,IL6,OSMR,YWHAZ,EFNA1,YWHAH,COL4A6
hsa04720	Long-term potentiation	0.946319525752132	-0.0551750018943589	66	12	0.00672268907563025	1785	6908	805,817,468,6196,673,369,5894,5604,5500,3845,10411,5566	CALM2,CAMK2D,ATF4,RPS6KA2,BRAF,ARAF,RAF1,MAP2K1,PPP1CB,KRAS,RAPGEF3,PRKACA
ko04720	Long-term potentiation	0.946319525752132	-0.0551750018943589	66	12	0.00672268907563025	1785	6908	805,817,468,6196,673,369,5894,5604,5500,3845,10411,5566	CALM2,CAMK2D,ATF4,RPS6KA2,BRAF,ARAF,RAF1,MAP2K1,PPP1CB,KRAS,RAPGEF3,PRKACA
hsa00072	Synthesis and degradation of ketone bodies	0.949796560025707	-0.0515074646617279	10	1	0.000560224089635854	1785	6908	3157	HMGCS1
ko00072	Synthesis and degradation of ketone bodies	0.949796560025707	-0.0515074646617279	10	1	0.000560224089635854	1785	6908	3157	HMGCS1
hsa00910	Nitrogen metabolism	0.957202868477266	-0.0437399262147717	17	2	0.00112044817927171	1785	6908	1373,11238	CPS1,CA5B
ko00910	Nitrogen metabolism	0.957202868477266	-0.0437399262147717	17	2	0.00112044817927171	1785	6908	1373,11238	CPS1,CA5B
hsa04916	Melanogenesis	0.958114413281189	-0.0427880788300827	100	19	0.0106442577030812	1785	6908	64764,148327,5894,5604,1906,3845,2535,2773,5566,6934,805,817,1499,80326,4286,2932,2771,1856,8321	CREB3L2,CREB3L4,RAF1,MAP2K1,EDN1,KRAS,FZD2,GNAI3,PRKACA,TCF7L2,CALM2,CAMK2D,CTNNB1,WNT10A,MITF,GSK3B,GNAI2,DVL2,FZD1
ko04916	Melanogenesis	0.958114413281189	-0.0427880788300827	100	19	0.0106442577030812	1785	6908	64764,148327,5894,5604,1906,3845,2535,2773,5566,6934,805,817,1499,80326,4286,2932,2771,1856,8321	CREB3L2,CREB3L4,RAF1,MAP2K1,EDN1,KRAS,FZD2,GNAI3,PRKACA,TCF7L2,CALM2,CAMK2D,CTNNB1,WNT10A,MITF,GSK3B,GNAI2,DVL2,FZD1
hsa04614	Renin-angiotensin system	0.959213307339157	-0.0416418019923015	23	3	0.00168067226890756	1785	6908	5547,4012,10159	PRCP,LNPEP,ATP6AP2
ko04614	Renin-angiotensin system	0.959213307339157	-0.0416418019923015	23	3	0.00168067226890756	1785	6908	5547,4012,10159	PRCP,LNPEP,ATP6AP2
hsa00430	Taurine and hypotaurine metabolism	0.962787737237344	-0.0379223097171226	11	1	0.000560224089635854	1785	6908	84890	ADO
ko00430	Taurine and hypotaurine metabolism	0.962787737237344	-0.0379223097171226	11	1	0.000560224089635854	1785	6908	84890	ADO
ko04620	Toll-like receptor signaling pathway	0.964758629830464	-0.035877333457524	106	20	0.0112044817927171	1785	6908	5609,208,5604,1147,2353,5606,8772,3725,3592,8517,5608,3569,3551,5601,5296,6772,8503,6885,10454,5970	MAP2K7,AKT2,MAP2K1,CHUK,FOS,MAP2K3,FADD,JUN,IL12A,IKBKG,MAP2K6,IL6,IKBKB,MAPK9,PIK3R2,STAT1,PIK3R3,MAP3K7,TAB1,RELA
hsa04620	Toll-like receptor signaling pathway	0.964758629830464	-0.035877333457524	106	20	0.0112044817927171	1785	6908	5609,208,5604,1147,2353,5606,8772,3725,3592,8517,5608,3569,3551,5601,5296,6772,8503,6885,10454,5970	MAP2K7,AKT2,MAP2K1,CHUK,FOS,MAP2K3,FADD,JUN,IL12A,IKBKG,MAP2K6,IL6,IKBKB,MAPK9,PIK3R2,STAT1,PIK3R3,MAP3K7,TAB1,RELA
hsa00770	Pantothenate and CoA biosynthesis	0.966686477971025	-0.0338810574329049	18	2	0.00112044817927171	1785	6908	80025,60496	PANK2,AASDHPPT
ko00770	Pantothenate and CoA biosynthesis	0.966686477971025	-0.0338810574329049	18	2	0.00112044817927171	1785	6908	80025,60496	PANK2,AASDHPPT
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.967386762111412	-0.0331569026734301	24	3	0.00168067226890756	1785	6908	2135,26035,26229	EXTL2,GLCE,B3GAT3
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.967386762111412	-0.0331569026734301	24	3	0.00168067226890756	1785	6908	2135,26035,26229	EXTL2,GLCE,B3GAT3
hsa04730	Long-term depression	0.967422389252645	-0.0331200751225458	60	10	0.00560224089635854	1785	6908	2768,673,369,5518,8681,5894,5604,3845,2773,2771	GNA12,BRAF,ARAF,PPP2R1A,JMJD7-PLA2G4B,RAF1,MAP2K1,KRAS,GNAI3,GNAI2
ko04730	Long-term depression	0.967422389252645	-0.0331200751225458	60	10	0.00560224089635854	1785	6908	2768,673,369,5518,8681,5894,5604,3845,2773,2771	GNA12,BRAF,ARAF,PPP2R1A,JMJD7-PLA2G4B,RAF1,MAP2K1,KRAS,GNAI3,GNAI2
ko00350	Tyrosine metabolism	0.967912550481842	-0.0326135361978208	35	5	0.00280112044817927	1785	6908	4282,4128,221,2805,2954	MIF,MAOA,ALDH3B1,GOT1,GSTZ1
hsa00350	Tyrosine metabolism	0.967912550481842	-0.0326135361978208	35	5	0.00280112044817927	1785	6908	4282,4128,2805,221,2954	MIF,MAOA,GOT1,ALDH3B1,GSTZ1
ko05321	Inflammatory bowel disease (IBD)	0.968298038127795	-0.0322153484662654	65	11	0.0061624649859944	1785	6908	3122,3108,3725,3592,3569,6778,6772,3109,3459,5970,6774	HLA-DRA,HLA-DMA,JUN,IL12A,IL6,STAT6,STAT1,HLA-DMB,IFNGR1,RELA,STAT3
hsa05321	Inflammatory bowel disease (IBD)	0.968298038127795	-0.0322153484662654	65	11	0.0061624649859944	1785	6908	3122,3108,3725,3592,3569,6778,6772,3109,3459,5970,6774	HLA-DRA,HLA-DMA,JUN,IL12A,IL6,STAT6,STAT1,HLA-DMB,IFNGR1,RELA,STAT3
hsa04923	Regulation of lipolysis in adipocytes	0.971631381880796	-0.0287787831982919	56	9	0.00504201680672269	1785	6908	5743,1081,208,5296,8503,154,2771,5566,2773	PTGS2,CGA,AKT2,PIK3R2,PIK3R3,ADRB2,GNAI2,PRKACA,GNAI3
hsa05142	Chagas disease (American trypanosomiasis)	0.974139697481981	-0.0262005590513341	104	19	0.0106442577030812	1785	6908	208,1147,2773,2353,8772,811,3725,8517,3592,5518,3569,5601,5296,3551,8503,5521,3459,5970,2771	AKT2,CHUK,GNAI3,FOS,FADD,CALR,JUN,IKBKG,IL12A,PPP2R1A,IL6,MAPK9,PIK3R2,IKBKB,PIK3R3,PPP2R2B,IFNGR1,RELA,GNAI2
ko05142	Chagas disease (American trypanosomiasis)	0.974139697481981	-0.0262005590513341	104	19	0.0106442577030812	1785	6908	208,1147,2773,2353,8772,811,3725,8517,3592,5518,3569,5601,5296,3551,8503,5521,3459,5970,2771	AKT2,CHUK,GNAI3,FOS,FADD,CALR,JUN,IKBKG,IL12A,PPP2R1A,IL6,MAPK9,PIK3R2,IKBKB,PIK3R3,PPP2R2B,IFNGR1,RELA,GNAI2
hsa04022	cGMP-PKG signaling pathway	0.974320371223028	-0.0260151061960594	167	33	0.0184873949579832	1785	6908	64764,148327,468,1388,4659,208,5894,5604,100271849,8654,4205,4209,154,7416,5997,2773,5581,805,572,2768,476,7408,488,5296,5500,8503,6722,483,4776,2969,2771,1386,9475	CREB3L2,CREB3L4,ATF4,ATF6B,PPP1R12A,AKT2,RAF1,MAP2K1,MEF2B,PDE5A,MEF2A,MEF2D,ADRB2,VDAC1,RGS2,GNAI3,PRKCE,CALM2,BAD,GNA12,ATP1A1,VASP,ATP2A2,PIK3R2,PPP1CB,PIK3R3,SRF,ATP1B3,NFATC4,GTF2I,GNAI2,ATF2,ROCK2
ko04022	cGMP-PKG signaling pathway	0.974320371223028	-0.0260151061960594	167	33	0.0184873949579832	1785	6908	64764,148327,468,1388,4659,208,5894,5604,100271849,8654,4205,4209,154,7416,5997,2773,5581,805,572,2768,476,7408,488,5296,5500,8503,6722,483,4776,2969,2771,1386,9475	CREB3L2,CREB3L4,ATF4,ATF6B,PPP1R12A,AKT2,RAF1,MAP2K1,MEF2B,PDE5A,MEF2A,MEF2D,ADRB2,VDAC1,RGS2,GNAI3,PRKCE,CALM2,BAD,GNA12,ATP1A1,VASP,ATP2A2,PIK3R2,PPP1CB,PIK3R3,SRF,ATP1B3,NFATC4,GTF2I,GNAI2,ATF2,ROCK2
hsa04925	Aldosterone synthesis and secretion	0.975178627258023	-0.0251346173205985	81	14	0.00784313725490196	1785	6908	64764,5581,805,466,817,148327,468,1388,221955,3164,4929,25865,5566,1386	CREB3L2,PRKCE,CALM2,ATF1,CAMK2D,CREB3L4,ATF4,ATF6B,DAGLB,NR4A1,NR4A2,PRKD2,PRKACA,ATF2
ko04925	Aldosterone synthesis and secretion	0.975178627258023	-0.0251346173205985	81	14	0.00784313725490196	1785	6908	64764,5581,805,466,817,148327,468,1388,221955,3164,4929,25865,5566,1386	CREB3L2,PRKCE,CALM2,ATF1,CAMK2D,CREB3L4,ATF4,ATF6B,DAGLB,NR4A1,NR4A2,PRKD2,PRKACA,ATF2
hsa05320	Autoimmune thyroid disease	0.975869228033526	-0.0244266892167619	52	8	0.00448179271708683	1785	6908	3122,3108,3107,1081,3134,3133,3105,3109	HLA-DRA,HLA-DMA,HLA-C,CGA,HLA-F,HLA-E,HLA-A,HLA-DMB
ko05320	Autoimmune thyroid disease	0.975869228033526	-0.0244266892167619	52	8	0.00448179271708683	1785	6908	3122,3108,3107,1081,3134,3133,3105,3109	HLA-DRA,HLA-DMA,HLA-C,CGA,HLA-F,HLA-E,HLA-A,HLA-DMB
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.979318455884712	-0.0208984024361246	26	3	0.00168067226890756	1785	6908	6484,10678,8704	ST3GAL4,B3GNT2,B4GALT2
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.979318455884712	-0.0208984024361246	26	3	0.00168067226890756	1785	6908	6484,10678,8704	ST3GAL4,B3GNT2,B4GALT2
ko04810	Regulation of actin cytoskeleton	0.980925745154508	-0.0192585152943689	214	43	0.0240896358543417	1785	6908	10163,673,2335,4659,8936,5894,5604,4627,324,81624,4628,1399,55845,998,5296,9138,54776,8503,6548,200576,7414,9475,5058,54961,10451,10152,6237,23365,87,3845,8394,10552,1729,10627,7114,2768,8396,369,8976,3688,4660,5500,10109	WASF2,BRAF,FN1,PPP1R12A,WASF1,RAF1,MAP2K1,MYH9,APC,DIAPH3,MYH10,CRKL,BRK1,CDC42,PIK3R2,ARHGEF1,PPP1R12C,PIK3R3,SLC9A1,PIKFYVE,VCL,ROCK2,PAK1,SSH3,VAV3,ABI2,RRAS,ARHGEF12,ACTN1,KRAS,PIP5K1A,ARPC1A,DIAPH1,MYL12A,TMSB4X,GNA12,PIP4K2B,ARAF,WASL,ITGB1,PPP1R12B,PPP1CB,ARPC2
hsa04810	Regulation of actin cytoskeleton	0.980925745154508	-0.0192585152943689	214	43	0.0240896358543417	1785	6908	10163,673,2335,4659,8936,5894,5604,4627,324,81624,4628,1399,55845,998,5296,9138,54776,8503,6548,200576,7414,9475,5058,54961,10451,10152,6237,23365,87,3845,8394,10552,1729,10627,7114,2768,8396,369,8976,3688,4660,5500,10109	WASF2,BRAF,FN1,PPP1R12A,WASF1,RAF1,MAP2K1,MYH9,APC,DIAPH3,MYH10,CRKL,BRK1,CDC42,PIK3R2,ARHGEF1,PPP1R12C,PIK3R3,SLC9A1,PIKFYVE,VCL,ROCK2,PAK1,SSH3,VAV3,ABI2,RRAS,ARHGEF12,ACTN1,KRAS,PIP5K1A,ARPC1A,DIAPH1,MYL12A,TMSB4X,GNA12,PIP4K2B,ARAF,WASL,ITGB1,PPP1R12B,PPP1CB,ARPC2
hsa04727	GABAergic synapse	0.981879185313344	-0.0182870074088666	88	15	0.00840336134453781	1785	6908	2744,11337,81539,59345,2788,51764,9001,2771,2773,57468,5566,2783,2787,23710,66008	GLS,GABARAP,SLC38A1,GNB4,GNG7,GNG13,HAP1,GNAI2,GNAI3,SLC12A5,PRKACA,GNB2,GNG5,GABARAPL1,TRAK2
ko04727	GABAergic synapse	0.981879185313344	-0.0182870074088666	88	15	0.00840336134453781	1785	6908	2744,11337,81539,59345,2788,51764,9001,2771,2773,57468,5566,2783,2787,23710,66008	GLS,GABARAP,SLC38A1,GNB4,GNG7,GNG13,HAP1,GNAI2,GNAI3,SLC12A5,PRKACA,GNB2,GNG5,GABARAPL1,TRAK2
hsa00053	Ascorbate and aldarate metabolism	0.983592127592481	-0.0165439723397973	27	3	0.00168067226890756	1785	6908	501,224,7358	ALDH7A1,ALDH3A2,UGDH
ko00053	Ascorbate and aldarate metabolism	0.983592127592481	-0.0165439723397973	27	3	0.00168067226890756	1785	6908	501,224,7358	ALDH7A1,ALDH3A2,UGDH
hsa00650	Butanoate metabolism	0.983592127592481	-0.0165439723397973	27	3	0.00168067226890756	1785	6908	79944,3157,3033	L2HGDH,HMGCS1,HADH
ko00650	Butanoate metabolism	0.983592127592481	-0.0165439723397973	27	3	0.00168067226890756	1785	6908	79944,3157,3033	L2HGDH,HMGCS1,HADH
hsa05323	Rheumatoid arthritis	0.984261071977801	-0.0158641000696177	89	15	0.00840336134453781	1785	6908	3122,3108,3725,51382,523,3569,3109,23545,535,528,51606,2353,529,284,9114	HLA-DRA,HLA-DMA,JUN,ATP6V1D,ATP6V1A,IL6,HLA-DMB,ATP6V0A2,ATP6V0A1,ATP6V1C1,ATP6V1H,FOS,ATP6V1E1,ANGPT1,ATP6V0D1
ko05323	Rheumatoid arthritis	0.984261071977801	-0.0158641000696177	89	15	0.00840336134453781	1785	6908	3122,3108,3725,51382,523,3569,3109,23545,535,528,51606,2353,529,284,9114	HLA-DRA,HLA-DMA,JUN,ATP6V1D,ATP6V1A,IL6,HLA-DMB,ATP6V0A2,ATP6V0A1,ATP6V1C1,ATP6V1H,FOS,ATP6V1E1,ANGPT1,ATP6V0D1
hsa00603	Glycosphingolipid biosynthesis - globo series	0.984850023626678	-0.0152659096803055	14	1	0.000560224089635854	1785	6908	6483	ST3GAL2
ko00603	Glycosphingolipid biosynthesis - globo series	0.984850023626678	-0.0152659096803055	14	1	0.000560224089635854	1785	6908	6483	ST3GAL2
ko04024	cAMP signaling pathway	0.985160752049176	-0.0149504510758031	199	39	0.0218487394957983	1785	6908	64764,673,4659,5894,5604,5566,3725,805,488,5296,5601,6548,8503,10411,5144,2771,5970,9475,2735,5058,10451,627,6755,148327,5141,6237,10257,208,11069,154,2353,2773,572,817,476,51,5500,483,8310	CREB3L2,BRAF,PPP1R12A,RAF1,MAP2K1,PRKACA,JUN,CALM2,ATP2A2,PIK3R2,MAPK9,SLC9A1,PIK3R3,RAPGEF3,PDE4D,GNAI2,RELA,ROCK2,GLI1,PAK1,VAV3,BDNF,SSTR5,CREB3L4,PDE4A,RRAS,ABCC4,AKT2,RAPGEF4,ADRB2,FOS,GNAI3,BAD,CAMK2D,ATP1A1,ACOX1,PPP1CB,ATP1B3,ACOX3
hsa04024	cAMP signaling pathway	0.985160752049176	-0.0149504510758031	199	39	0.0218487394957983	1785	6908	64764,673,4659,5894,5604,5566,3725,805,488,5296,5601,6548,8503,10411,5144,2771,5970,9475,2735,5058,10451,627,6755,148327,5141,6237,10257,208,11069,154,2353,2773,572,817,476,51,5500,483,8310	CREB3L2,BRAF,PPP1R12A,RAF1,MAP2K1,PRKACA,JUN,CALM2,ATP2A2,PIK3R2,MAPK9,SLC9A1,PIK3R3,RAPGEF3,PDE4D,GNAI2,RELA,ROCK2,GLI1,PAK1,VAV3,BDNF,SSTR5,CREB3L4,PDE4A,RRAS,ABCC4,AKT2,RAPGEF4,ADRB2,FOS,GNAI3,BAD,CAMK2D,ATP1A1,ACOX1,PPP1CB,ATP1B3,ACOX3
ko05133	Pertussis	0.985441066153112	-0.0146659551383308	75	12	0.00672268907563025	1785	6908	3725,805,3592,840,3569,5601,3688,2771,2773,5970,2353,725	JUN,CALM2,IL12A,CASP7,IL6,MAPK9,ITGB1,GNAI2,GNAI3,RELA,FOS,C4BPB
hsa05133	Pertussis	0.985441066153112	-0.0146659551383308	75	12	0.00672268907563025	1785	6908	3725,805,3592,840,3569,5601,3688,2771,2773,5970,2353,725	JUN,CALM2,IL12A,CASP7,IL6,MAPK9,ITGB1,GNAI2,GNAI3,RELA,FOS,C4BPB
ko04670	Leukocyte transendothelial migration	0.985746636548956	-0.0143559183033074	118	21	0.0117647058823529	1785	6908	10451,1495,11069,50848,87,2773,10627,7408,1499,998,5296,3688,5781,8503,2185,1500,10411,1365,7414,2771,9475	VAV3,CTNNA1,RAPGEF4,F11R,ACTN1,GNAI3,MYL12A,VASP,CTNNB1,CDC42,PIK3R2,ITGB1,PTPN11,PIK3R3,PTK2B,CTNND1,RAPGEF3,CLDN3,VCL,GNAI2,ROCK2
hsa04670	Leukocyte transendothelial migration	0.985746636548956	-0.0143559183033074	118	21	0.0117647058823529	1785	6908	10451,1495,11069,50848,87,2773,10627,7408,1499,998,5296,3688,5781,8503,2185,1500,10411,1365,7414,2771,9475	VAV3,CTNNA1,RAPGEF4,F11R,ACTN1,GNAI3,MYL12A,VASP,CTNNB1,CDC42,PIK3R2,ITGB1,PTPN11,PIK3R3,PTK2B,CTNND1,RAPGEF3,CLDN3,VCL,GNAI2,ROCK2
ko04062	Chemokine signaling pathway	0.987052327318956	-0.0130322244200859	187	36	0.0201680672268908	1785	6908	673,5894,5604,1147,6777,2920,2870,5566,2783,1399,998,6464,3551,5296,8503,3717,51764,6774,2771,5970,2787,9475,5058,10451,2931,208,2788,3845,2773,6773,8517,59345,8976,6772,2932,2185	BRAF,RAF1,MAP2K1,CHUK,STAT5B,CXCL2,GRK6,PRKACA,GNB2,CRKL,CDC42,SHC1,IKBKB,PIK3R2,PIK3R3,JAK2,GNG13,STAT3,GNAI2,RELA,GNG5,ROCK2,PAK1,VAV3,GSK3A,AKT2,GNG7,KRAS,GNAI3,STAT2,IKBKG,GNB4,WASL,STAT1,GSK3B,PTK2B
hsa04062	Chemokine signaling pathway	0.987052327318956	-0.0130322244200859	187	36	0.0201680672268908	1785	6908	673,5894,5604,1147,6777,2920,2870,5566,2783,1399,998,6464,3551,5296,8503,3717,51764,6774,2771,5970,2787,9475,5058,10451,2931,208,2788,3845,2773,6773,8517,59345,8976,6772,2932,2185	BRAF,RAF1,MAP2K1,CHUK,STAT5B,CXCL2,GRK6,PRKACA,GNB2,CRKL,CDC42,SHC1,IKBKB,PIK3R2,PIK3R3,JAK2,GNG13,STAT3,GNAI2,RELA,GNG5,ROCK2,PAK1,VAV3,GSK3A,AKT2,GNG7,KRAS,GNAI3,STAT2,IKBKG,GNB4,WASL,STAT1,GSK3B,PTK2B
hsa04014	Ras signaling pathway	0.987232337484291	-0.0128498695965462	227	45	0.0252100840336134	1785	6908	4763,5966,5894,10928,8681,5604,5900,1147,81579,598,5566,2783,27,805,6464,998,3551,5296,5601,5781,8503,55770,51764,4233,5970,2787,9610,5058,6237,208,2788,5868,3845,2002,5869,572,8517,2114,1969,59345,5863,1942,382,5878,284	NF1,REL,RAF1,RALBP1,JMJD7-PLA2G4B,MAP2K1,RALGDS,CHUK,PLA2G12A,BCL2L1,PRKACA,GNB2,ABL2,CALM2,SHC1,CDC42,IKBKB,PIK3R2,MAPK9,PTPN11,PIK3R3,EXOC2,GNG13,MET,RELA,GNG5,RIN1,PAK1,RRAS,AKT2,GNG7,RAB5A,KRAS,ELK1,RAB5B,BAD,IKBKG,ETS2,EPHA2,GNB4,RGL2,EFNA1,ARF6,RAB5C,ANGPT1
hsa04550	Signaling pathways regulating pluripotency of stem cells	0.987295690669635	-0.0127856991371122	142	26	0.0145658263305322	1785	6908	3397,659,208,5894,56916,6929,55183,5604,3398,3845,324,2535,6498,463,1499,4609,80326,5296,2932,8503,3717,6774,4211,1856,3720,8321	ID1,BMPR2,AKT2,RAF1,SMARCAD1,TCF3,RIF1,MAP2K1,ID2,KRAS,APC,FZD2,SKIL,ZFHX3,CTNNB1,MYC,WNT10A,PIK3R2,GSK3B,PIK3R3,JAK2,STAT3,MEIS1,DVL2,JARID2,FZD1
ko04550	Signaling pathways regulating pluripotency of stem cells	0.987295690669635	-0.0127856991371122	142	26	0.0145658263305322	1785	6908	3397,659,208,5894,56916,6929,55183,5604,3398,3845,324,2535,6498,463,1499,4609,80326,5296,2932,8503,3717,6774,4211,1856,3720,8321	ID1,BMPR2,AKT2,RAF1,SMARCAD1,TCF3,RIF1,MAP2K1,ID2,KRAS,APC,FZD2,SKIL,ZFHX3,CTNNB1,MYC,WNT10A,PIK3R2,GSK3B,PIK3R3,JAK2,STAT3,MEIS1,DVL2,JARID2,FZD1
hsa04725	Cholinergic synapse	0.989563152506198	-0.0104916933321357	111	19	0.0106442577030812	1785	6908	64764,148327,468,208,2788,5604,3845,2773,2353,5566,2783,817,59345,5296,8503,3717,51764,2771,2787	CREB3L2,CREB3L4,ATF4,AKT2,GNG7,MAP2K1,KRAS,GNAI3,FOS,PRKACA,GNB2,CAMK2D,GNB4,PIK3R2,PIK3R3,JAK2,GNG13,GNAI2,GNG5
hsa04510	Focal adhesion	0.989657157001315	-0.01039670189057	207	40	0.0224089635854342	1785	6908	673,2335,4659,7094,5894,5604,329,3914,3725,1399,595,7791,7408,998,1499,6464,5296,5601,54776,8503,4233,7414,9475,5170,5058,10451,330,208,87,857,2002,1729,10627,572,29780,3688,5500,2932,4660,1288	BRAF,FN1,PPP1R12A,TLN1,RAF1,MAP2K1,BIRC2,LAMB3,JUN,CRKL,CCND1,ZYX,VASP,CDC42,CTNNB1,SHC1,PIK3R2,MAPK9,PPP1R12C,PIK3R3,MET,VCL,ROCK2,PDPK1,PAK1,VAV3,BIRC3,AKT2,ACTN1,CAV1,ELK1,DIAPH1,MYL12A,BAD,PARVB,ITGB1,PPP1CB,GSK3B,PPP1R12B,COL4A6
ko04510	Focal adhesion	0.989657157001315	-0.01039670189057	207	40	0.0224089635854342	1785	6908	673,2335,4659,7094,5894,5604,329,3914,3725,1399,595,7791,7408,998,1499,6464,5296,5601,54776,8503,4233,7414,9475,5170,5058,10451,330,208,87,857,2002,1729,10627,572,29780,3688,5500,2932,4660,1288	BRAF,FN1,PPP1R12A,TLN1,RAF1,MAP2K1,BIRC2,LAMB3,JUN,CRKL,CCND1,ZYX,VASP,CDC42,CTNNB1,SHC1,PIK3R2,MAPK9,PPP1R12C,PIK3R3,MET,VCL,ROCK2,PDPK1,PAK1,VAV3,BIRC3,AKT2,ACTN1,CAV1,ELK1,DIAPH1,MYL12A,BAD,PARVB,ITGB1,PPP1CB,GSK3B,PPP1R12B,COL4A6
ko04630	Jak-STAT signaling pathway	0.990278462490694	-0.00976910016084092	158	29	0.0162464985994398	1785	6908	2475,5894,208,6777,598,7297,8027,3587,6773,30837,595,3592,8651,6778,4609,3569,5296,10379,122809,6772,5781,8503,9180,3717,5292,2273,3459,6774,9655	MTOR,RAF1,AKT2,STAT5B,BCL2L1,TYK2,STAM,IL10RA,STAT2,SOCS7,CCND1,IL12A,SOCS1,STAT6,MYC,IL6,PIK3R2,IRF9,SOCS4,STAT1,PTPN11,PIK3R3,OSMR,JAK2,PIM1,FHL1,IFNGR1,STAT3,SOCS5
hsa04630	Jak-STAT signaling pathway	0.990278462490694	-0.00976910016084092	158	29	0.0162464985994398	1785	6908	2475,5894,208,6777,598,7297,8027,3587,6773,30837,595,3592,8651,6778,4609,3569,5296,10379,122809,6772,5781,8503,9180,3717,5292,2273,3459,6774,9655	MTOR,RAF1,AKT2,STAT5B,BCL2L1,TYK2,STAM,IL10RA,STAT2,SOCS7,CCND1,IL12A,SOCS1,STAT6,MYC,IL6,PIK3R2,IRF9,SOCS4,STAT1,PTPN11,PIK3R3,OSMR,JAK2,PIM1,FHL1,IFNGR1,STAT3,SOCS5
hsa04726	Serotonergic synapse	0.990888649243253	-0.00915311298011384	112	19	0.0106442577030812	1785	6908	673,5894,8681,2788,5604,3845,3361,2773,5566,2783,5743,369,59345,4128,51764,10411,2771,2787,1843	BRAF,RAF1,JMJD7-PLA2G4B,GNG7,MAP2K1,KRAS,HTR5A,GNAI3,PRKACA,GNB2,PTGS2,ARAF,GNB4,MAOA,GNG13,RAPGEF3,GNAI2,GNG5,DUSP1
hsa05310	Asthma	0.99191379248987	-0.00811907820551101	30	3	0.00168067226890756	1785	6908	3122,3108,3109	HLA-DRA,HLA-DMA,HLA-DMB
ko05310	Asthma	0.99191379248987	-0.00811907820551101	30	3	0.00168067226890756	1785	6908	3122,3108,3109	HLA-DRA,HLA-DMA,HLA-DMB
hsa04911	Insulin secretion	0.993394570962769	-0.0066273414307576	85	13	0.00728291316526611	1785	6908	64764,817,476,148327,468,1388,11069,5864,483,6616,5566,1386,27445	CREB3L2,CAMK2D,ATP1A1,CREB3L4,ATF4,ATF6B,RAPGEF4,RAB3A,ATP1B3,SNAP25,PRKACA,ATF2,PCLO
hsa04270	Vascular smooth muscle contraction	0.994158856730053	-0.00585826947092355	120	20	0.0112044817927171	1785	6908	673,4659,8681,5894,5604,23365,81579,5566,140465,805,5581,2768,369,800,9138,54776,4660,4637,5500,9475	BRAF,PPP1R12A,JMJD7-PLA2G4B,RAF1,MAP2K1,ARHGEF12,PLA2G12A,PRKACA,MYL6B,CALM2,PRKCE,GNA12,ARAF,CALD1,ARHGEF1,PPP1R12C,PPP1R12B,MYL6,PPP1CB,ROCK2
ko04270	Vascular smooth muscle contraction	0.994158856730053	-0.00585826947092355	120	20	0.0112044817927171	1785	6908	673,4659,8681,5894,5604,23365,81579,5566,140465,805,5581,2768,369,800,9138,54776,4660,4637,5500,9475	BRAF,PPP1R12A,JMJD7-PLA2G4B,RAF1,MAP2K1,ARHGEF12,PLA2G12A,PRKACA,MYL6B,CALM2,PRKCE,GNA12,ARAF,CALD1,ARHGEF1,PPP1R12C,PPP1R12B,MYL6,PPP1CB,ROCK2
hsa05032	Morphine addiction	0.994368899834503	-0.00564701458193605	91	14	0.00784313725490196	1785	6908	5141,59345,2788,5150,5151,51764,2870,5144,27115,2771,2773,5566,2783,2787	PDE4A,GNB4,GNG7,PDE7A,PDE8A,GNG13,GRK6,PDE4D,PDE7B,GNAI2,GNAI3,PRKACA,GNB2,GNG5
ko05032	Morphine addiction	0.994368899834503	-0.00564701458193605	91	14	0.00784313725490196	1785	6908	5141,59345,2788,5150,5151,51764,2870,5144,27115,2771,2773,5566,2783,2787	PDE4A,GNB4,GNG7,PDE7A,PDE8A,GNG13,GRK6,PDE4D,PDE7B,GNAI2,GNAI3,PRKACA,GNB2,GNG5
hsa04913	Ovarian steroidogenesis	0.995191652485952	-0.00481994480776918	50	6	0.00336134453781513	1785	6908	5743,5566,1081,654,8681,1545	PTGS2,PRKACA,CGA,BMP6,JMJD7-PLA2G4B,CYP1B1
ko04913	Ovarian steroidogenesis	0.995191652485952	-0.00481994480776918	50	6	0.00336134453781513	1785	6908	5743,5566,1081,654,8681,1545	PTGS2,PRKACA,CGA,BMP6,JMJD7-PLA2G4B,CYP1B1
hsa05146	Amoebiasis	0.995304183615323	-0.00470687636778586	107	17	0.00952380952380952	1785	6908	384,3592,2335,3569,7879,5296,8503,5868,87,5869,5566,1992,5970,1288,7414,5878,3914	ARG2,IL12A,FN1,IL6,RAB7A,PIK3R2,PIK3R3,RAB5A,ACTN1,RAB5B,PRKACA,SERPINB1,RELA,COL4A6,VCL,RAB5C,LAMB3
ko05146	Amoebiasis	0.995304183615323	-0.00470687636778586	107	17	0.00952380952380952	1785	6908	384,3592,2335,3569,7879,5296,8503,5868,87,5869,5566,1992,5970,1288,7414,5878,3914	ARG2,IL12A,FN1,IL6,RAB7A,PIK3R2,PIK3R3,RAB5A,ACTN1,RAB5B,PRKACA,SERPINB1,RELA,COL4A6,VCL,RAB5C,LAMB3
ko00500	Starch and sucrose metabolism	0.995589675471614	-0.00442007869954778	56	7	0.00392156862745098	1785	6908	283209,2997,92579,7360,2990,5837,7358	PGM2L1,GYS1,G6PC3,UGP2,GUSB,PYGM,UGDH
hsa00500	Starch and sucrose metabolism	0.995589675471614	-0.00442007869954778	56	7	0.00392156862745098	1785	6908	2997,283209,92579,7360,2990,5837,7358	GYS1,PGM2L1,G6PC3,UGP2,GUSB,PYGM,UGDH
hsa04360	Axon guidance	0.995701917905596	-0.00430734540174866	127	21	0.0117647058823529	1785	6908	5058,4690,2044,23365,3845,2773,57556,9901,1969,998,1808,3688,2932,10512,4776,1942,4233,2771,9475,10509,7869	PAK1,NCK1,EPHA5,ARHGEF12,KRAS,GNAI3,SEMA6A,SRGAP3,EPHA2,CDC42,DPYSL2,ITGB1,GSK3B,SEMA3C,NFATC4,EFNA1,MET,GNAI2,ROCK2,SEMA4B,SEMA3B
ko04360	Axon guidance	0.995701917905596	-0.00430734540174866	127	21	0.0117647058823529	1785	6908	5058,4690,2044,23365,3845,2773,57556,9901,1969,998,1808,3688,2932,10512,4776,1942,4233,2771,9475,10509,7869	PAK1,NCK1,EPHA5,ARHGEF12,KRAS,GNAI3,SEMA6A,SRGAP3,EPHA2,CDC42,DPYSL2,ITGB1,GSK3B,SEMA3C,NFATC4,EFNA1,MET,GNAI2,ROCK2,SEMA4B,SEMA3B
ko00565	Ether lipid metabolism	0.995874991083234	-0.00413354023530719	45	5	0.00280112044817927	1785	6908	85465,81579,5049,5051,8681	EPT1,PLA2G12A,PAFAH1B2,PAFAH2,JMJD7-PLA2G4B
hsa00565	Ether lipid metabolism	0.995874991083234	-0.00413354023530719	45	5	0.00280112044817927	1785	6908	85465,5049,81579,5051,8681	EPT1,PAFAH1B2,PLA2G12A,PAFAH2,JMJD7-PLA2G4B
hsa04540	Gap junction	0.995930269366474	-0.00407803452463196	88	13	0.00728291316526611	1785	6908	5607,10383,5894,5604,3845,7082,5598,2773,2771,5566,983,203068,10381	MAP2K5,TUBB4B,RAF1,MAP2K1,KRAS,TJP1,MAPK7,GNAI3,GNAI2,PRKACA,CDK1,TUBB,TUBB3
ko04540	Gap junction	0.995930269366474	-0.00407803452463196	88	13	0.00728291316526611	1785	6908	5607,10383,5894,5604,3845,7082,5598,2773,2771,5566,983,203068,10381	MAP2K5,TUBB4B,RAF1,MAP2K1,KRAS,TJP1,MAPK7,GNAI3,GNAI2,PRKACA,CDK1,TUBB,TUBB3
ko04713	Circadian entrainment	0.997029641443481	-0.00297477882685815	95	14	0.00784313725490196	1785	6908	805,817,5187,59345,2788,51764,2771,2773,9252,2353,5566,2783,2787,8864	CALM2,CAMK2D,PER1,GNB4,GNG7,GNG13,GNAI2,GNAI3,RPS6KA5,FOS,PRKACA,GNB2,GNG5,PER2
hsa04713	Circadian entrainment	0.997029641443481	-0.00297477882685815	95	14	0.00784313725490196	1785	6908	805,817,5187,59345,2788,51764,2771,2773,9252,2353,5566,2783,2787,8864	CALM2,CAMK2D,PER1,GNB4,GNG7,GNG13,GNAI2,GNAI3,RPS6KA5,FOS,PRKACA,GNB2,GNG5,PER2
hsa00591	Linoleic acid metabolism	0.998121854947958	-0.00187991097791656	29	2	0.00112044817927171	1785	6908	81579,8681	PLA2G12A,JMJD7-PLA2G4B
ko00591	Linoleic acid metabolism	0.998121854947958	-0.00187991097791656	29	2	0.00112044817927171	1785	6908	81579,8681	PLA2G12A,JMJD7-PLA2G4B
ko05414	Dilated cardiomyopathy	0.998580226156256	-0.00142078267761787	89	12	0.00672268907563025	1785	6908	59283,7169,7170,488,2010,783,7171,3688,784,5566,1605,4000	CACNG8,TPM2,TPM3,ATP2A2,EMD,CACNB2,TPM4,ITGB1,CACNB3,PRKACA,DAG1,LMNA
hsa05414	Dilated cardiomyopathy	0.998580226156256	-0.00142078267761787	89	12	0.00672268907563025	1785	6908	59283,7169,7170,488,2010,783,7171,3688,784,5566,1605,4000	CACNG8,TPM2,TPM3,ATP2A2,EMD,CACNB2,TPM4,ITGB1,CACNB3,PRKACA,DAG1,LMNA
hsa04971	Gastric acid secretion	0.998862637033097	-0.00113801025500968	74	9	0.00504201680672269	1785	6908	805,817,476,6548,6522,483,2771,5566,2773	CALM2,CAMK2D,ATP1A1,SLC9A1,SLC4A2,ATP1B3,GNAI2,PRKACA,GNAI3
ko04971	Gastric acid secretion	0.998862637033097	-0.00113801025500968	74	9	0.00504201680672269	1785	6908	805,817,476,6548,6522,483,2771,5566,2773	CALM2,CAMK2D,ATP1A1,SLC9A1,SLC4A2,ATP1B3,GNAI2,PRKACA,GNAI3
hsa05204	Chemical carcinogenesis	0.999145193255946	-0.000855172299673778	81	10	0.00560224089635854	1785	6908	373156,5743,221,883,119391,9,4259,56267,405,1545	GSTK1,PTGS2,ALDH3B1,CCBL1,GSTO2,NAT1,MGST3,CCBL2,ARNT,CYP1B1
ko05204	Chemical carcinogenesis	0.999145193255946	-0.000855172299673778	81	10	0.00560224089635854	1785	6908	373156,5743,221,883,119391,9,4259,56267,405,1545	GSTK1,PTGS2,ALDH3B1,CCBL1,GSTO2,NAT1,MGST3,CCBL2,ARNT,CYP1B1
hsa04750	Inflammatory mediator regulation of TRP channels	0.999265078509305	-0.000735191677879672	98	13	0.00728291316526611	1785	6908	5581,805,817,5608,8681,5296,5601,5734,5500,8503,5566,5606,3269	PRKCE,CALM2,CAMK2D,MAP2K6,JMJD7-PLA2G4B,PIK3R2,MAPK9,PTGER4,PPP1CB,PIK3R3,PRKACA,MAP2K3,HRH1
ko04750	Inflammatory mediator regulation of TRP channels	0.999265078509305	-0.000735191677879672	98	13	0.00728291316526611	1785	6908	5581,805,817,5608,8681,5296,5601,5734,5500,8503,5566,5606,3269	PRKCE,CALM2,CAMK2D,MAP2K6,JMJD7-PLA2G4B,PIK3R2,MAPK9,PTGER4,PPP1CB,PIK3R3,PRKACA,MAP2K3,HRH1
ko04672	Intestinal immune network for IgA production	0.999360532178314	-0.000639672368439064	47	4	0.00224089635854342	1785	6908	3122,3108,3569,3109	HLA-DRA,HLA-DMA,IL6,HLA-DMB
hsa04672	Intestinal immune network for IgA production	0.999360532178314	-0.000639672368439064	47	4	0.00224089635854342	1785	6908	3122,3108,3569,3109	HLA-DRA,HLA-DMA,IL6,HLA-DMB
hsa04975	Fat digestion and absorption	0.999468960346376	-0.000531180705118991	41	3	0.00168067226890756	1785	6908	81579,10555,10554	PLA2G12A,AGPAT2,AGPAT1
ko04975	Fat digestion and absorption	0.999468960346376	-0.000531180705118991	41	3	0.00168067226890756	1785	6908	81579,10555,10554	PLA2G12A,AGPAT2,AGPAT1
ko05143	African trypanosomiasis	0.999515950992169	-0.000484166197370099	34	2	0.00112044817927171	1785	6908	3592,3569	IL12A,IL6
hsa05143	African trypanosomiasis	0.999515950992169	-0.000484166197370099	34	2	0.00112044817927171	1785	6908	3592,3569	IL12A,IL6
hsa04015	Rap1 signaling pathway	0.999578094243483	-0.000421994783792799	211	35	0.0196078431372549	1785	6908	9170,673,3397,7094,5894,5604,5900,51735,5606,1399,805,7408,1499,998,5296,5584,8503,10411,4233,2771,6237,208,11069,3845,2773,260425,889,1969,5608,3688,25865,1500,1942,9223,284	LPAR2,BRAF,ID1,TLN1,RAF1,MAP2K1,RALGDS,RAPGEF6,MAP2K3,CRKL,CALM2,VASP,CTNNB1,CDC42,PIK3R2,PRKCI,PIK3R3,RAPGEF3,MET,GNAI2,RRAS,AKT2,RAPGEF4,KRAS,GNAI3,MAGI3,KRIT1,EPHA2,MAP2K6,ITGB1,PRKD2,CTNND1,EFNA1,MAGI1,ANGPT1
ko04015	Rap1 signaling pathway	0.999578094243483	-0.000421994783792799	211	35	0.0196078431372549	1785	6908	9170,673,3397,7094,5894,5604,5900,51735,5606,1399,805,7408,1499,998,5296,5584,8503,10411,4233,2771,6237,208,11069,3845,2773,260425,889,1969,5608,3688,25865,1500,1942,9223,284	LPAR2,BRAF,ID1,TLN1,RAF1,MAP2K1,RALGDS,RAPGEF6,MAP2K3,CRKL,CALM2,VASP,CTNNB1,CDC42,PIK3R2,PRKCI,PIK3R3,RAPGEF3,MET,GNAI2,RRAS,AKT2,RAPGEF4,KRAS,GNAI3,MAGI3,KRIT1,EPHA2,MAP2K6,ITGB1,PRKD2,CTNND1,EFNA1,MAGI1,ANGPT1
hsa04950	Maturity onset diabetes of the young	0.999585682910923	-0.000414402942116864	26	1	0.000560224089635854	1785	6908	3280	HES1
ko04950	Maturity onset diabetes of the young	0.999585682910923	-0.000414402942116864	26	1	0.000560224089635854	1785	6908	3280	HES1
hsa05144	Malaria	0.999605220491467	-0.000394857454478157	49	4	0.00224089635854342	1785	6908	3592,4233,6382,3569	IL12A,MET,SDC1,IL6
ko05144	Malaria	0.999605220491467	-0.000394857454478157	49	4	0.00224089635854342	1785	6908	3592,4233,6382,3569	IL12A,MET,SDC1,IL6
hsa00590	Arachidonic acid metabolism	0.999630939809701	-0.000369128309771318	62	6	0.00336134453781513	1785	6908	5743,81579,10728,8681,493869,80142	PTGS2,PLA2G12A,PTGES3,JMJD7-PLA2G4B,GPX8,PTGES2
ko00590	Arachidonic acid metabolism	0.999630939809701	-0.000369128309771318	62	6	0.00336134453781513	1785	6908	5743,81579,10728,8681,493869,80142	PTGS2,PLA2G12A,PTGES3,JMJD7-PLA2G4B,GPX8,PTGES2
hsa04650	Natural killer cell mediated cytotoxicity	0.999672752810875	-0.000327300746171321	134	19	0.0106442577030812	1785	6908	5058,10451,79465,673,5894,3133,5604,3845,3105,6464,369,5296,5781,8503,2185,3107,3459,80328,80329	PAK1,VAV3,ULBP3,BRAF,RAF1,HLA-E,MAP2K1,KRAS,HLA-A,SHC1,ARAF,PIK3R2,PTPN11,PIK3R3,PTK2B,HLA-C,IFNGR1,ULBP2,ULBP1
ko04650	Natural killer cell mediated cytotoxicity	0.999672752810875	-0.000327300746171321	134	19	0.0106442577030812	1785	6908	5058,10451,79465,673,5894,3133,5604,3845,3105,6464,369,5296,5781,8503,2185,3107,3459,80328,80329	PAK1,VAV3,ULBP3,BRAF,RAF1,HLA-E,MAP2K1,KRAS,HLA-A,SHC1,ARAF,PIK3R2,PTPN11,PIK3R3,PTK2B,HLA-C,IFNGR1,ULBP2,ULBP1
hsa05340	Primary immunodeficiency	0.999720215440071	-0.000279823706931453	36	2	0.00112044817927171	1785	6908	8517,6890	IKBKG,TAP1
ko05340	Primary immunodeficiency	0.999720215440071	-0.000279823706931453	36	2	0.00112044817927171	1785	6908	8517,6890	IKBKG,TAP1
hsa04611	Platelet activation	0.999730068316721	-0.000269968121393546	130	18	0.0100840336134454	1785	6908	4659,7094,208,8681,23365,2773,5566,10627,7408,6786,9138,5296,5584,3688,5500,8503,2771,9475	PPP1R12A,TLN1,AKT2,JMJD7-PLA2G4B,ARHGEF12,GNAI3,PRKACA,MYL12A,VASP,STIM1,ARHGEF1,PIK3R2,PRKCI,ITGB1,PPP1CB,PIK3R3,GNAI2,ROCK2
hsa04924	Renin secretion	0.999764110252276	-0.000235917574086382	64	6	0.00336134453781513	1785	6908	805,154,2771,2773,5566,5734	CALM2,ADRB2,GNAI2,GNAI3,PRKACA,PTGER4
ko04924	Renin secretion	0.999764110252276	-0.000235917574086382	64	6	0.00336134453781513	1785	6908	805,154,2771,2773,5566,5734	CALM2,ADRB2,GNAI2,GNAI3,PRKACA,PTGER4
ko04744	Phototransduction	0.999772746463085	-0.000227279362912831	28	1	0.000560224089635854	1785	6908	805	CALM2
hsa04744	Phototransduction	0.999772746463085	-0.000227279362912831	28	1	0.000560224089635854	1785	6908	805	CALM2
hsa04976	Bile secretion	0.999805629476628	-0.000194389415770243	71	7	0.00392156862745098	1785	6908	6548,6522,476,483,10257,5566,3156	SLC9A1,SLC4A2,ATP1A1,ATP1B3,ABCC4,PRKACA,HMGCR
ko04976	Bile secretion	0.999805629476628	-0.000194389415770243	71	7	0.00392156862745098	1785	6908	6548,6522,476,483,10257,5566,3156	SLC9A1,SLC4A2,ATP1A1,ATP1B3,ABCC4,PRKACA,HMGCR
ko04723	Retrograde endocannabinoid signaling	0.99984583760286	-0.00015417428138336	101	12	0.00672268907563025	1785	6908	5743,221955,59345,2788,5601,51764,2771,2773,5566,222236,2783,2787	PTGS2,DAGLB,GNB4,GNG7,MAPK9,GNG13,GNAI2,GNAI3,PRKACA,NAPEPLD,GNB2,GNG5
hsa04723	Retrograde endocannabinoid signaling	0.99984583760286	-0.00015417428138336	101	12	0.00672268907563025	1785	6908	5743,221955,59345,2788,5601,51764,2771,2773,5566,222236,2783,2787	PTGS2,DAGLB,GNB4,GNG7,MAPK9,GNG13,GNAI2,GNAI3,PRKACA,NAPEPLD,GNB2,GNG5
ko00982	Drug metabolism - cytochrome P450	0.999904981168514	-9.50233460608081e-05	68	6	0.00336134453781513	1785	6908	4128,373156,221,119391,2329,4259	MAOA,GSTK1,ALDH3B1,GSTO2,FMO4,MGST3
hsa00982	Drug metabolism - cytochrome P450	0.999904981168514	-9.50233460608081e-05	68	6	0.00336134453781513	1785	6908	4128,373156,221,119391,2329,4259	MAOA,GSTK1,ALDH3B1,GSTO2,FMO4,MGST3
ko04972	Pancreatic secretion	0.999947540262071	-5.24611139887244e-05	95	10	0.00560224089635854	1785	6908	4218,476,488,219931,6548,81579,6522,483,5874,8766	RAB8A,ATP1A1,ATP2A2,TPCN2,SLC9A1,PLA2G12A,SLC4A2,ATP1B3,RAB27B,RAB11A
hsa04972	Pancreatic secretion	0.999947540262071	-5.24611139887244e-05	95	10	0.00560224089635854	1785	6908	4218,476,488,219931,6548,81579,6522,483,5874,8766	RAB8A,ATP1A1,ATP2A2,TPCN2,SLC9A1,PLA2G12A,SLC4A2,ATP1B3,RAB27B,RAB11A
ko04742	Taste transduction	0.999960384036193	-3.9616748540319e-05	51	3	0.00168067226890756	1785	6908	51764,5566,83756	GNG13,PRKACA,TAS1R3
hsa04742	Taste transduction	0.999960384036193	-3.9616748540319e-05	51	3	0.00168067226890756	1785	6908	51764,5566,83756	GNG13,PRKACA,TAS1R3
ko04724	Glutamatergic synapse	0.999963366508999	-3.66341620241822e-05	114	13	0.00728291316526611	1785	6908	2744,9456,81539,59345,8681,2788,1742,51764,2771,5566,2773,2783,2787	GLS,HOMER1,SLC38A1,GNB4,JMJD7-PLA2G4B,GNG7,DLG4,GNG13,GNAI2,PRKACA,GNAI3,GNB2,GNG5
hsa04724	Glutamatergic synapse	0.999963366508999	-3.66341620241822e-05	114	13	0.00728291316526611	1785	6908	2744,9456,81539,59345,8681,2788,1742,51764,2771,5566,2773,2783,2787	GLS,HOMER1,SLC38A1,GNB4,JMJD7-PLA2G4B,GNG7,DLG4,GNG13,GNAI2,PRKACA,GNAI3,GNB2,GNG5
hsa00980	Metabolism of xenobiotics by cytochrome P450	0.999976465150166	-2.35351267826988e-05	74	6	0.00336134453781513	1785	6908	27294,373156,221,119391,4259,1545	DHDH,GSTK1,ALDH3B1,GSTO2,MGST3,CYP1B1
ko00980	Metabolism of xenobiotics by cytochrome P450	0.999976465150166	-2.35351267826988e-05	74	6	0.00336134453781513	1785	6908	27294,373156,221,119391,4259,1545	DHDH,GSTK1,ALDH3B1,GSTO2,MGST3,CYP1B1
hsa05150	Staphylococcus aureus infection	0.999986286396829	-1.37136972035863e-05	55	3	0.00168067226890756	1785	6908	3122,3108,3109	HLA-DRA,HLA-DMA,HLA-DMB
ko05150	Staphylococcus aureus infection	0.999986286396829	-1.37136972035863e-05	55	3	0.00168067226890756	1785	6908	3122,3108,3109	HLA-DRA,HLA-DMA,HLA-DMB
hsa00830	Retinol metabolism	0.999992803645056	-7.19638083782365e-06	65	4	0.00224089635854342	1785	6908	53630,8228,9249,157506	BCO1,PNPLA4,DHRS3,RDH10
ko00830	Retinol metabolism	0.999992803645056	-7.19638083782365e-06	65	4	0.00224089635854342	1785	6908	53630,8228,9249,157506	BCO1,PNPLA4,DHRS3,RDH10
hsa04512	ECM-receptor interaction	0.999994829892768	-5.17012059656674e-06	87	7	0.00392156862745098	1785	6908	3161,2335,1288,6382,1605,3914,3688	HMMR,FN1,COL4A6,SDC1,DAG1,LAMB3,ITGB1
ko04512	ECM-receptor interaction	0.999994829892768	-5.17012059656674e-06	87	7	0.00392156862745098	1785	6908	3161,2335,1288,6382,1605,3914,3688	HMMR,FN1,COL4A6,SDC1,DAG1,LAMB3,ITGB1
ko04970	Salivary secretion	0.999996767814903	-3.23219032090581e-06	89	7	0.00392156862745098	1785	6908	805,6548,6522,476,483,154,5566	CALM2,SLC9A1,SLC4A2,ATP1A1,ATP1B3,ADRB2,PRKACA
hsa04974	Protein digestion and absorption	0.999996767814903	-3.23219032090581e-06	89	7	0.00392156862745098	1785	6908	1294,476,483,6520,1288,5547,1303	COL7A1,ATP1A1,ATP1B3,SLC3A2,COL4A6,PRCP,COL12A1
ko04974	Protein digestion and absorption	0.999996767814903	-3.23219032090581e-06	89	7	0.00392156862745098	1785	6908	1294,476,483,6520,1288,5547,1303	COL7A1,ATP1A1,ATP1B3,SLC3A2,COL4A6,PRCP,COL12A1
hsa04970	Salivary secretion	0.999996767814903	-3.23219032090581e-06	89	7	0.00392156862745098	1785	6908	805,6548,6522,476,483,154,5566	CALM2,SLC9A1,SLC4A2,ATP1A1,ATP1B3,ADRB2,PRKACA
ko04610	Complement and coagulation cascades	0.999997439852922	-2.56015035527342e-06	69	4	0.00224089635854342	1785	6908	966,1604,725,2152	CD59,CD55,C4BPB,F3
hsa04610	Complement and coagulation cascades	0.999997439852922	-2.56015035527342e-06	69	4	0.00224089635854342	1785	6908	966,1604,725,2152	CD59,CD55,C4BPB,F3
ko04640	Hematopoietic cell lineage	0.999998973072943	-1.02692758413692e-06	87	6	0.00336134453781513	1785	6908	3122,966,1604,2323,3569,7037	HLA-DRA,CD59,CD55,FLT3LG,IL6,TFRC
hsa04640	Hematopoietic cell lineage	0.999998973072943	-1.02692758413692e-06	87	6	0.00336134453781513	1785	6908	3122,966,1604,2323,3569,7037	HLA-DRA,CD59,CD55,FLT3LG,IL6,TFRC
ko00140	Steroid hormone biosynthesis	0.999999418360058	-5.81640111351157e-07	58	2	0.00112044817927171	1785	6908	6820,1545	SULT2B1,CYP1B1
hsa00140	Steroid hormone biosynthesis	0.999999418360058	-5.81640111351157e-07	58	2	0.00112044817927171	1785	6908	6820,1545	SULT2B1,CYP1B1
ko05206	MicroRNAs in cancer	0.999999911917846	-8.80821583235617e-08	297	41	0.02296918767507	1785	6908	90427,659,2475,5894,4194,5604,7157,324,7329,9252,3925,54541,1399,5581,595,6464,8651,4609,3551,5296,1027,4082,5292,2065,4233,5598,6774,10253,1021,1545,23411,993,1871,3845,995,2744,5743,9759,3190,1870,1029	BMF,BMPR2,MTOR,RAF1,MDM4,MAP2K1,TP53,APC,UBE2I,RPS6KA5,STMN1,DDIT4,CRKL,PRKCE,CCND1,SHC1,SOCS1,MYC,IKBKB,PIK3R2,CDKN1B,MARCKS,PIM1,ERBB3,MET,MAPK7,STAT3,SPRY2,CDK6,CYP1B1,SIRT1,CDC25A,E2F3,KRAS,CDC25C,GLS,PTGS2,HDAC4,HNRNPK,E2F2,CDKN2A
hsa05206	MicroRNAs in cancer	0.999999911917846	-8.80821583235617e-08	297	41	0.02296918767507	1785	6908	90427,659,2475,5894,4194,5604,7157,324,7329,9252,3925,54541,1399,5581,595,6464,8651,4609,3551,5296,1027,4082,5292,2065,4233,5598,6774,10253,1021,1545,23411,993,1871,3845,995,2744,5743,9759,3190,1870,1029	BMF,BMPR2,MTOR,RAF1,MDM4,MAP2K1,TP53,APC,UBE2I,RPS6KA5,STMN1,DDIT4,CRKL,PRKCE,CCND1,SHC1,SOCS1,MYC,IKBKB,PIK3R2,CDKN1B,MARCKS,PIM1,ERBB3,MET,MAPK7,STAT3,SPRY2,CDK6,CYP1B1,SIRT1,CDC25A,E2F3,KRAS,CDC25C,GLS,PTGS2,HDAC4,HNRNPK,E2F2,CDKN2A
ko04514	Cell adhesion molecules (CAMs)	0.999999972847727	-2.71522732869256e-08	142	12	0.00672268907563025	1785	6908	3122,3108,3134,3133,3688,3109,50848,3107,1365,214,6382,3105	HLA-DRA,HLA-DMA,HLA-F,HLA-E,ITGB1,HLA-DMB,F11R,HLA-C,CLDN3,ALCAM,SDC1,HLA-A
hsa04514	Cell adhesion molecules (CAMs)	0.999999972847727	-2.71522732869256e-08	142	12	0.00672268907563025	1785	6908	3122,3108,3134,3133,3688,3109,50848,3107,1365,214,6382,3105	HLA-DRA,HLA-DMA,HLA-F,HLA-E,ITGB1,HLA-DMB,F11R,HLA-C,CLDN3,ALCAM,SDC1,HLA-A
ko04020	Calcium signaling pathway	0.999999998120278	-1.87972185662568e-09	179	16	0.00896358543417367	1785	6908	805,817,488,6786,5257,2185,2065,154,3361,7416,5256,56848,5566,5261,93129,3269	CALM2,CAMK2D,ATP2A2,STIM1,PHKB,PTK2B,ERBB3,ADRB2,HTR5A,VDAC1,PHKA2,SPHK2,PRKACA,PHKG2,ORAI3,HRH1
hsa04020	Calcium signaling pathway	0.999999998120278	-1.87972185662568e-09	179	16	0.00896358543417367	1785	6908	805,817,488,6786,5257,2185,2065,154,3361,7416,5256,56848,5566,5261,93129,3269	CALM2,CAMK2D,ATP2A2,STIM1,PHKB,PTK2B,ERBB3,ADRB2,HTR5A,VDAC1,PHKA2,SPHK2,PRKACA,PHKG2,ORAI3,HRH1
hsa04740	Olfactory transduction	0.999999999905308	-9.4692372442389e-11	404	3	0.00168067226890756	1785	6908	805,817,5566	CALM2,CAMK2D,PRKACA
ko04740	Olfactory transduction	0.999999999905308	-9.4692372442389e-11	404	3	0.00168067226890756	1785	6908	805,817,5566	CALM2,CAMK2D,PRKACA
hsa04060	Cytokine-cytokine receptor interaction	0.999999999937932	-6.2068264072581e-11	265	12	0.00672268907563025	1785	6908	8771,3592,659,3569,23529,27242,9180,2920,4233,2323,3459,3587	TNFRSF6B,IL12A,BMPR2,IL6,CLCF1,TNFRSF21,OSMR,CXCL2,MET,FLT3LG,IFNGR1,IL10RA
ko04060	Cytokine-cytokine receptor interaction	0.999999999937932	-6.2068264072581e-11	265	12	0.00672268907563025	1785	6908	8771,3592,659,3569,23529,27242,9180,2920,4233,2323,3459,3587	TNFRSF6B,IL12A,BMPR2,IL6,CLCF1,TNFRSF21,OSMR,CXCL2,MET,FLT3LG,IFNGR1,IL10RA
ko04080	Neuroactive ligand-receptor interaction	0.999999999940075	-5.99246336527086e-11	276	9	0.00504201680672269	1785	6908	9170,6755,2908,1081,5734,154,9294,3361,3269	LPAR2,SSTR5,NR3C1,CGA,PTGER4,ADRB2,S1PR2,HTR5A,HRH1
hsa04080	Neuroactive ligand-receptor interaction	0.999999999940075	-5.99246336527086e-11	276	9	0.00504201680672269	1785	6908	9170,6755,2908,1081,5734,154,9294,3361,3269	LPAR2,SSTR5,NR3C1,CGA,PTGER4,ADRB2,S1PR2,HTR5A,HRH1
hsa00290	Valine, leucine and isoleucine biosynthesis	0.999999999999021	-9.79175074355965e-13	4	0	0	1785	6908
ko00290	Valine, leucine and isoleucine biosynthesis	0.999999999999021	-9.79175074355965e-13	4	0	0	1785	6908
hsa00524	Butirosin and neomycin biosynthesis	1.00000000000093	9.30870614965218e-13	5	0	0	1785	6908
ko00524	Butirosin and neomycin biosynthesis	1.00000000000093	9.30870614965218e-13	5	0	0	1785	6908
hsa00472	D-Arginine and D-ornithine metabolism	1.0000000000072	7.2043482290951e-12	1	0	0	1785	6908
ko00472	D-Arginine and D-ornithine metabolism	1.0000000000072	7.2043482290951e-12	1	0	0	1785	6908
ko05033	Nicotine addiction	1.00000000004411	4.41069803212292e-11	40	0	0	1785	6908
hsa05033	Nicotine addiction	1.00000000004411	4.41069803212292e-11	40	0	0	1785	6908