TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
WP411	mRNA processing	5.67865223369933e-15	-32.8020624731331	134	79	0.0649671052631579	1216	4455	3182,10978,1659,6635,83443,10992,3181,6429,3191,51692,3192,5094,1477,6421,10772,10291,11338,6629,5681,8731,5725,6433,3183,10921,140890,9129,10907,10421,1665,6426,8405,11051,10236,10972,7307,5496,8243,9128,2521,6637,9785,8899,6627,3178,10594,1195,6431,10250,3276,23283,10946,10482,3187,56339,283459,9343,3184,57396,6729,22803,4904,24148,55660,6430,3275,6829,8175,5430,6626,23450,4686,11129,3188,27316,1478,3190,6428,6633,9584	HNRNPAB,CLP1,DHX8,SNRPE,SF3B5,SF3B2,HNRNPA2B1,SRSF4,HNRNPL,CPSF3,HNRNPU,PCBP2,CSTF1,SFPQ,SRSF10,SF3A1,U2AF2,SNRPB2,PSKH1,RNMT,PTBP1,SFSWAP,HNRNPC,RNPS1,SREK1,PRPF3,TXNL4A,CD2BP2,DHX15,SRSF1,SPOP,NUDT21,HNRNPR,TMED10,U2AF1,PPM1G,SMC1A,PRPF4,FUS,SNRPG,DHX38,PRPF4B,SNRPA1,HNRNPA1,PRPF8,CLK1,SRSF6,SRRM1,PRMT1,CSTF2T,SF3A3,NXF1,HNRNPH1,METTL3,GATC,EFTUD2,HNRNPD,CLK4,SRP54,XRN2,YBX1,PRPF6,PRPF40A,SRSF5,PRMT2,SUPT5H,SF3A2,POLR2A,SNRPA,SF3B3,NCBP1,CLASRP,HNRNPH2,RBMX,CSTF2,HNRNPK,SRSF3,SNRPD2,RBM39
WP477	Cytoplasmic Ribosomal Proteins	8.18452753553678e-12	-25.5287756299802	118	67	0.0550986842105263	1216	4455	6181,6235,6156,6193,9801,6135,6147,6217,6196,6134,6194,6168,6227,6222,6207,6159,11224,7311,6133,6160,6169,6142,6232,4736,6203,3921,6167,6201,6233,6208,9045,6173,6198,2197,6146,6188,6231,6224,6202,6122,6209,6138,6125,23521,6137,9349,6139,6205,6170,6155,6143,6199,6154,6144,6128,6171,6132,6229,25873,6189,6130,6161,6158,6210,6223,6152,6206	RPLP2,RPS29,RPL30,RPS5,MRPL19,RPL11,RPL23A,RPS16,RPS6KA2,RPL10,RPS6,RPL37A,RPS21,RPS18,RPS13,RPL29,RPL35,UBA52,RPL9,RPL31,RPL38,RPL18A,RPS27,RPL10A,RPS9,RPSA,RPL37,RPS7,RPS27A,RPS14,RPL14,RPL36A,RPS6KB1,FAU,RPL22,RPS3,RPS26,RPS20,RPS8,RPL3,RPS15,RPL15,RPL5,RPL13A,RPL13,RPL23,RPL17,RPS11,RPL39,RPL27,RPL19,RPS6KB2,RPL26,RPL21,RPL6,RPL41,RPL8,RPS24,RPL36,RPS3A,RPL7A,RPL32,RPL28,RPS15A,RPS19,RPL24,RPS12
WP231	TNF-alpha/NF-kB Signaling Pathway	2.92927650267104e-10	-21.9510954648191	194	93	0.0764802631578947	1216	4455	23291,1540,5607,25885,2177,6156,1147,1460,10013,7531,7329,5566,329,5707,9775,3551,10270,835,200081,5134,5971,4791,2969,5970,9994,54476,6207,11140,4215,330,8767,3326,4528,208,10971,57805,857,64343,7763,7532,1654,8517,5719,5709,10293,6772,2932,2289,6198,9861,10454,9618,5700,86,3066,7323,5693,257397,5966,7186,10238,5977,5713,8518,4176,9252,7341,8533,6205,4174,5781,3320,2091,28511,64425,7128,8738,5702,6132,6128,10399,8772,840,51082,9908,7322,10128,7534,10848,7533,8945,11124,26133	FBXW11,CYLD,MAP2K5,POLR1A,FANCD2,RPL30,CHUK,CSNK2B,HDAC6,YWHAE,UBE2I,PRKACA,BIRC2,PSMD1,EIF4A3,IKBKB,AKAP8,CASP2,TXLNA,PDCD2,RELB,NFKB2,GTF2I,RELA,CASP8AP2,RNF216,RPS13,CDC37,MAP3K3,BIRC3,RIPK2,HSP90AB1,MTIF2,AKT2,YWHAQ,CCAR2,CAV1,AZI2,ZFAND5,YWHAG,DDX3X,IKBKG,PSMD13,PSMD3,TRAIP,STAT1,GSK3B,FKBP5,RPS6KB1,PSMD6,TAB1,TRAF4,PSMC1,ACTL6A,HDAC2,UBE2D3,PSMB5,TAB3,REL,TRAF2,DCAF7,DPF2,PSMD7,IKBKAP,MCM7,RPS6KA5,SUMO1,COPS3,RPS11,MCM5,PTPN11,HSP90AA1,FBL,NKIRAS2,POLR1E,TNFAIP3,CRADD,PSMC3,RPL8,RPL6,GNB2L1,FADD,CASP7,POLR1D,G3BP2,UBE2D2,LRPPRC,YWHAZ,PPP1R13L,YWHAH,BTRC,FAF1,TRPC4AP
WP2446	RB in Cancer	5.80127841051773e-10	-21.2677726210695	87	51	0.0419407894736842	1216	4455	3146,4175,3015,5894,7157,6240,1111,4998,6596,25942,4863,4176,3925,7153,4173,6118,595,7465,5111,890,4609,7272,10733,1027,1021,2956,8819,6595,993,5984,5983,5931,1019,5422,6502,1871,6241,3275,54443,2189,10714,983,79027,8318,24137,8243,3148,9133,1870,11124,4172	HMGB1,MCM6,H2AFZ,RAF1,TP53,RRM1,CHEK1,ORC1,HLTF,SIN3A,NPAT,MCM7,STMN1,TOP2A,MCM4,RPA2,CCND1,WEE1,PCNA,CCNA2,MYC,TTK,PLK4,CDKN1B,CDK6,MSH6,SAP30,SMARCA2,CDC25A,RFC4,RFC3,RBBP7,CDK4,POLA1,SKP2,E2F3,RRM2,PRMT2,ANLN,FANCG,POLD3,CDK1,ZNF655,CDC45,KIF4A,SMC1A,HMGB2,CCNB2,E2F2,FAF1,MCM3
WP183	Proteasome Degradation	1.33831609166913e-09	-20.4318536612359	65	41	0.0337171052631579	1216	4455	7323,5689,5693,3015,7317,3133,3134,5713,5715,3105,4734,6184,5687,5707,5696,5717,6185,3107,7314,5686,5694,5692,5702,5695,5682,5710,7347,7316,5691,3012,5719,5714,5709,7322,3014,7320,5690,10197,5705,9861,5700	UBE2D3,PSMB1,PSMB5,H2AFZ,UBA1,HLA-E,HLA-F,PSMD7,PSMD9,HLA-A,NEDD4,RPN1,PSMA6,PSMD1,PSMB8,PSMD11,RPN2,HLA-C,UBB,PSMA5,PSMB6,PSMB4,PSMC3,PSMB7,PSMA1,PSMD4,UCHL3,UBC,PSMB3,HIST1H2AE,PSMD13,PSMD8,PSMD3,UBE2D2,H2AFX,UBE2B,PSMB2,PSME3,PSMC5,PSMD6,PSMC1
WP179	Cell cycle	8.34964245567566e-09	-18.60104711868	102	55	0.0452302631578947	1216	4455	55388,4175,1875,9232,7157,1111,4998,10013,7531,4176,4173,7465,890,5111,8555,4174,8379,1027,545,23595,1021,1876,993,4999,902,1019,991,6502,1871,10971,701,990,4171,995,10014,983,7532,8318,9759,5000,5933,5001,4085,8243,84515,2932,7534,11200,7533,8556,1870,9133,4172,3066,1029	MCM10,MCM6,E2F5,PTTG1,TP53,CHEK1,ORC1,HDAC6,YWHAE,MCM7,MCM4,WEE1,CCNA2,PCNA,CDC14B,MCM5,MAD1L1,CDKN1B,ATR,ORC3,CDK6,E2F6,CDC25A,ORC2,CCNH,CDK4,CDC20,SKP2,E2F3,YWHAQ,BUB1B,CDC6,MCM2,CDC25C,HDAC5,CDK1,YWHAG,CDC45,HDAC4,ORC4,RBL1,ORC5,MAD2L1,SMC1A,MCM8,GSK3B,YWHAZ,CHEK2,YWHAH,CDC14A,E2F2,CCNB2,MCM3,HDAC2,CDKN2A
WP466	DNA Replication	1.03373017889004e-07	-16.0849218577743	42	28	0.0230263157894737	1216	4455	23649,5984,55388,5983,4999,4175,7311,5422,990,4998,4171,10714,4176,5424,5982,7316,6118,8318,4173,5111,5000,4174,5001,5981,23595,57804,4172,5425	POLA2,RFC4,MCM10,RFC3,ORC2,MCM6,UBA52,POLA1,CDC6,ORC1,MCM2,POLD3,MCM7,POLD1,RFC2,UBC,RPA2,CDC45,MCM4,PCNA,ORC4,MCM5,ORC5,RFC1,ORC3,POLD4,MCM3,POLD2
WP405	Eukaryotic Transcription Initiation	2.57763615092077e-07	-15.1712228925848	41	27	0.0222039473684211	1216	4455	6884,6877,902,2071,6908,5440,25885,171568,2958,51728,5430,5432,661,2968,51082,2963,5434,2965,6879,6883,2960,2068,55703,2959,6878,64425,5431	TAF13,TAF5,CCNH,ERCC3,TBP,POLR2K,POLR1A,POLR3H,GTF2A2,POLR3K,POLR2A,POLR2C,POLR3D,GTF2H4,POLR1D,GTF2F2,POLR2E,GTF2H1,TAF7,TAF12,GTF2E1,ERCC2,POLR3B,GTF2B,TAF6,POLR1E,POLR2B
WP111	Electron Transport Chain	3.59712073859343e-06	-12.5353768273439	93	46	0.0378289473684211	1216	4455	4698,4729,4712,6391,7381,7351,521,506,1347,374291,4709,7386,4723,517,1337,10476,4708,7385,4728,4731,1349,4700,4696,4705,55967,4720,516,10632,93974,1350,27089,1353,4701,514,9551,6392,513,9167,1351,4694,9377,7388,4725,498,4713,1340	NDUFA5,NDUFV2,NDUFB6,SDHC,UQCRB,UCP2,ATP5I,ATP5B,COX7A2,NDUFS7,NDUFB3,UQCRFS1,NDUFV1,ATP5G2,COX6A1,ATP5H,NDUFB2,UQCRC2,NDUFS8,NDUFV3,COX7B,NDUFA6,NDUFA3,NDUFA10,NDUFA12,NDUFS2,ATP5G1,ATP5L,ATPIF1,COX7C,UQCRQ,COX11,NDUFA7,ATP5E,ATP5J2,SDHD,ATP5D,COX7A2L,COX8A,NDUFA1,COX5A,UQCRH,NDUFS5,ATP5A1,NDUFB7,COX6B1
WP45	G1 to S cell cycle control	5.80024411358269e-06	-12.0576105527489	68	36	0.0296052631578947	1216	4455	1030,23649,4175,1388,1875,7157,4998,4176,6118,595,4173,7465,5111,4609,4174,1027,23595,1032,1021,901,1876,993,148327,4999,902,1019,1871,4171,983,8318,5000,5933,5001,1870,1029,4172	CDKN2B,POLA2,MCM6,ATF6B,E2F5,TP53,ORC1,MCM7,RPA2,CCND1,MCM4,WEE1,PCNA,MYC,MCM5,CDKN1B,ORC3,CDKN2D,CDK6,CCNG2,E2F6,CDC25A,CREB3L4,ORC2,CCNH,CDK4,E2F3,MCM2,CDK1,CDC45,ORC4,RBL1,ORC5,E2F2,CDKN2A,MCM3
WP1982	SREBP signalling	2.92069668091841e-05	-10.4411032877923	64	33	0.0271381578947368	1216	4455	6396,51141,2475,9871,7376,10483,5566,1595,3422,3157,6721,56681,9632,3837,6667,2222,3156,23411,10802,10484,1024,2931,4597,51128,22872,3638,22937,1622,51586,2224,47,22926,57678	SEC13,INSIG2,MTOR,SEC24D,NR1H2,SEC23B,PRKACA,CYP51A1,IDI1,HMGCS1,SREBF2,SAR1A,SEC24C,KPNB1,SP1,FDFT1,HMGCR,SIRT1,SEC24A,SEC23A,CDK8,GSK3A,MVD,SAR1B,SEC31A,INSIG1,SCAP,DBI,MED15,FDPS,ACLY,ATF6,GPAM
WP107	Translation Factors	4.04404737150608e-05	-10.1156794498583	57	30	0.0246710526315789	1216	4455	1984,8893,1975,8664,1974,1964,9451,8672,1973,9669,1915,8666,8667,8661,1933,8894,1938,1968,23277,1967,8892,1979,8665,2107,8662,8891,1983,1977,26986,1936	EIF5A,EIF2B5,EIF4B,EIF3D,EIF4A2,EIF1AX,EIF2AK3,EIF4G3,EIF4A1,EIF5B,EEF1A1,EIF3G,EIF3H,EIF3A,EEF1B2,EIF2S2,EEF2,EIF2S3,CLUH,EIF2B1,EIF2B2,EIF4EBP2,EIF3F,ETF1,EIF3B,EIF2B3,EIF5,EIF4E,PABPC1,EEF1D
WP1984	Integrated Breast Cancer Pathway	4.36820281926888e-05	-10.0385737946228	152	64	0.0526315789473684	1216	4455	2896,23077,673,659,9175,2475,4763,5245,7157,4092,1111,1147,8438,641,595,3725,466,7465,998,1499,4609,57223,5296,581,4436,545,58515,84640,4091,2956,6667,3156,23411,5058,140739,1263,2241,993,6237,2931,1019,842,3845,1605,27005,79027,8772,6009,572,7248,8202,675,369,253959,6772,55526,7517,23613,11200,2197,55671,10454,196,9958	GRN,MYCBP2,BRAF,BMPR2,MAP3K13,MTOR,NF1,PHB,TP53,SMAD7,CHEK1,CHUK,RAD54L,BLM,CCND1,JUN,ATF1,WEE1,CDC42,CTNNB1,MYC,PPP4R3B,PIK3R2,BAX,MSH2,ATR,SELK,USP38,SMAD6,MSH6,SP1,HMGCR,SIRT1,PAK1,UBE2F,PLK3,FER,CDC25A,RRAS,GSK3A,CDK4,CASP9,KRAS,DAG1,USP21,ZNF655,FADD,RHEB,BAD,TSC1,NCOA3,BRCA2,ARAF,RALGAPA1,STAT1,DHTKD1,XRCC3,ZMYND8,CHEK2,FAU,PPP4R3A,TAB1,AHR,USP15
WP437	EGFR1 Signaling Pathway	0.000111035246938171	-9.10566286707357	177	71	0.0583881578947368	1216	4455	5753,5607,5894,10928,5604,6777,25942,51079,30011,5606,1399,6196,6464,8651,998,8882,5296,8503,10006,4215,4690,842,868,5868,857,6773,378,6622,8976,6772,2185,1500,5573,6004,3636,29924,5900,9252,1915,1999,3725,5586,466,4609,5584,5781,3717,5598,8520,6774,10253,6667,1843,5058,7050,10451,5609,5931,2060,9219,5782,3845,5339,2002,2353,369,160,2886,5306,6633,3875	PTK6,MAP2K5,RAF1,RALBP1,MAP2K1,STAT5B,SIN3A,NDUFA13,SH3KBP1,MAP2K3,CRKL,RPS6KA2,SHC1,SOCS1,CDC42,ZPR1,PIK3R2,PIK3R3,ABI1,MAP3K3,NCK1,CASP9,CBLB,RAB5A,CAV1,STAT2,ARF4,SNCA,WASL,STAT1,PTK2B,CTNND1,PRKAR1A,RGS16,INPPL1,EPN1,RALGDS,RPS6KA5,EEF1A1,ELF3,JUN,PKN2,ATF1,MYC,PRKCI,PTPN11,JAK2,MAPK7,HAT1,STAT3,SPRY2,SP1,DUSP1,PAK1,TGIF1,VAV3,MAP2K7,RBBP7,EPS15,MTA2,PTPN12,KRAS,PLEC,ELK1,FOS,ARAF,AP2A1,GRB7,PITPNA,SNRPD2,KRT18
WP531	Mismatch repair	0.000206831911621193	-8.48360411572033	9	8	0.00657894736842105	1216	4455	9156,3978,4292,5981,5111,5424,2956,4436	EXO1,LIG1,MLH1,RFC1,PCNA,POLD1,MSH6,MSH2
WP197	Cholesterol biosynthesis	0.000242642170587087	-8.32392274891391	17	12	0.00986842105263158	1216	4455	1595,3157,3422,6721,6307,4597,2224,10654,6309,1717,3156,2222	CYP51A1,HMGCS1,IDI1,SREBF2,MSMO1,MVD,FDPS,PMVK,SC5D,DHCR7,HMGCR,FDFT1
WP623	Oxidative phosphorylation	0.000299141931933683	-8.11459240846123	54	27	0.0222039473684211	1216	4455	516,10632,4698,4729,4712,521,506,514,4701,9551,374291,513,4723,517,10476,126328,4708,4728,4731,4725,498,4700,4696,4713,4705,4720,10159	ATP5G1,ATP5L,NDUFA5,NDUFV2,NDUFB6,ATP5I,ATP5B,ATP5E,NDUFA7,ATP5J2,NDUFS7,ATP5D,NDUFV1,ATP5G2,ATP5H,NDUFA11,NDUFB2,NDUFS8,NDUFV3,NDUFS5,ATP5A1,NDUFA6,NDUFA3,NDUFB7,NDUFA10,NDUFS2,ATP6AP2
WP404	Nucleotide Metabolism	0.000459852663273411	-7.68460441701896	20	13	0.0106907894736842	1216	4455	159,5423,654364,10797,5422,5428,6303,6240,4831,3614,6241,5424,5631	ADSS,POLB,NME1-NME2,MTHFD2,POLA1,POLG,SAT1,RRM1,NME2,IMPDH1,RRM2,POLD1,PRPS1
WP366	TGF-beta Receptor Signaling Pathway	0.000920304723236764	-6.9908057218532	151	59	0.0485197368421053	1216	4455	7323,51433,1875,7157,4092,10664,4205,10755,5606,7341,595,3725,114790,1499,4609,3726,51343,5296,2354,10393,55802,163,51434,9972,6885,4091,1386,11171,1021,3837,6642,6667,7050,993,79753,1019,3312,29882,467,55914,857,8697,2353,8021,983,7421,6498,817,7514,996,1616,5933,5608,10987,4802,7322,10454,9133,8945	UBE2D3,ANAPC5,E2F5,TP53,SMAD7,CTCF,MEF2A,GIPC1,MAP2K3,SUMO1,CCND1,JUN,STK11IP,CTNNB1,MYC,JUNB,FZR1,PIK3R2,FOSB,ANAPC10,DCP1A,AP2B1,ANAPC7,NUP153,MAP3K7,SMAD6,ATF2,STRAP,CDK6,KPNB1,SNX1,SP1,TGIF1,CDC25A,SNIP1,CDK4,HSPA8,ANAPC2,ATF3,ERBB2IP,CAV1,CDC23,FOS,NUP214,CDK1,VDR,SKIL,CAMK2D,XPO1,CDC27,DAXX,RBL1,MAP2K6,COPS5,NFYC,UBE2D2,TAB1,CCNB2,BTRC
WP78	TCA Cycle	0.0013658656475709	-6.59596687730398	17	11	0.00904605263157895	1216	4455	50,8802,6391,4191,1431,2271,4967,3420,1738,1743,6392	ACO2,SUCLG1,SDHC,MDH2,CS,FH,OGDH,IDH3B,DLD,DLST,SDHD
WP2377	Integrated Pancreatic Cancer Pathway	0.00145054252753954	-6.53581763560508	194	72	0.0592105263157895	1216	4455	4052,25885,3732,5894,9232,5604,7157,324,1147,3925,595,5111,890,1499,1027,7159,10411,175,23411,5914,5163,2931,4690,1019,3326,842,701,2958,995,1605,2287,6009,572,5743,675,10555,1616,5933,6772,11200,2972,1030,1958,6908,7186,6240,3978,1111,641,7153,3725,4609,3726,5601,581,5598,4091,6667,7150,5915,5058,627,2512,5422,5893,3845,2100,8772,5308,840,10848,4217	LTBP1,POLR1A,CD82,RAF1,PTTG1,MAP2K1,TP53,APC,CHUK,STMN1,CCND1,PCNA,CCNA2,CTNNB1,CDKN1B,TP53BP2,RAPGEF3,AGA,SIRT1,RARA,PDK1,GSK3A,NCK1,CDK4,HSP90AB1,CASP9,BUB1B,GTF2A2,CDC25C,DAG1,FKBP3,RHEB,BAD,PTGS2,BRCA2,AGPAT2,DAXX,RBL1,STAT1,CHEK2,BRF1,CDKN2B,EGR1,TBP,TRAF2,RRM1,LIG1,CHEK1,BLM,TOP2A,JUN,MYC,JUNB,MAPK9,BAX,MAPK7,SMAD6,SP1,TOP1,RARB,PAK1,BDNF,FTL,POLA1,RAD52,KRAS,ESR2,FADD,PITX2,CASP7,PPP1R13L,MAP3K5
WP707	DNA damage response	0.0014803848077975	-6.51545321973305	67	30	0.0246710526315789	1216	4455	993,1643,5883,5810,55367,1019,842,7157,2177,5893,1111,54205,5884,995,983,6118,595,5366,4609,4616,581,3014,8243,1027,84126,545,5981,11200,9133,1021	CDC25A,DDB2,RAD9A,RAD1,PIDD1,CDK4,CASP9,TP53,FANCD2,RAD52,CHEK1,CYCS,RAD17,CDC25C,CDK1,RPA2,CCND1,PMAIP1,MYC,GADD45B,BAX,H2AFX,SMC1A,CDKN1B,ATRIP,ATR,RFC1,CHEK2,CCNB2,CDK6
WP2034	Leptin signaling pathway	0.00230102296687265	-6.07440148672159	60	27	0.0222039473684211	1216	4455	2475,5966,5894,5604,6777,1147,598,2002,30837,595,8517,3840,5770,998,6464,3551,5296,25970,6194,6772,5781,581,3717,6198,6774,5970,6667	MTOR,REL,RAF1,MAP2K1,STAT5B,CHUK,BCL2L1,ELK1,SOCS7,CCND1,IKBKG,KPNA4,PTPN1,CDC42,SHC1,IKBKB,PIK3R2,SH2B1,RPS6,STAT1,PTPN11,BAX,JAK2,RPS6KB1,STAT3,RELA,SP1
WP2361	Gastric cancer network 1	0.00374162378754995	-5.58823559398516	42	20	0.0164473684210526	1216	4455	8367,1063,1894,3021,9585,324,8363,8368,8360,8365,7153,4173,8362,8607,8364,6286,55125,11065,86,54476	HIST1H4E,CENPF,ECT2,H3F3B,KIF20B,APC,HIST1H4J,HIST1H4L,HIST1H4D,HIST1H4H,TOP2A,MCM4,HIST1H4K,RUVBL1,HIST1H4C,S100P,CEP192,UBE2C,ACTL6A,RNF216
WP2011	SREBF and miR33 in cholesterol and lipid homeostasis	0.0104049685096706	-4.56547184560237	18	10	0.00822368421052632	1216	4455	23411,3157,6721,2475,51548,51586,5562,10891,10062,3156	SIRT1,HMGCS1,SREBF2,MTOR,SIRT6,MED15,PRKAA1,PPARGC1A,NR1H3,HMGCR
WP2363	Gastric cancer network 2	0.010517755368882	-4.55469046241576	34	16	0.0131578947368421	1216	4455	7153,55593,5984,5983,29028,1499,29089,4609,7157,51316,27101,157769,5884,11065,6277,55215	TOP2A,OTUD5,RFC4,RFC3,ATAD2,CTNNB1,UBE2T,MYC,TP53,PLAC8,CACYBP,FAM91A1,RAD17,UBE2C,S100A6,FANCI
WP400	p38 MAPK Signaling Pathway	0.010517755368882	-4.55469046241576	34	16	0.0131578947368421	1216	4455	3150,7186,8550,4209,2002,9252,6464,998,1616,4609,5608,6772,4217,6885,1386,1649	HMGN1,TRAF2,MAPKAPK5,MEF2D,ELK1,RPS6KA5,SHC1,CDC42,DAXX,MYC,MAP2K6,STAT1,MAP3K5,MAP3K7,ATF2,DDIT3
WP481	Insulin Signaling	0.0112114870682999	-4.49081639518311	163	58	0.0476973684210526	1216	4455	5607,6517,3636,1958,9175,2475,5894,5562,10211,5604,30849,9252,4641,5606,3725,5770,6196,6464,8651,10487,3551,5601,5296,5781,23678,5584,6446,2997,8503,6885,5598,1977,6199,5170,4215,5289,23433,5609,2931,208,868,6616,6810,2002,2353,6009,7248,5608,5597,7494,4296,6722,2932,6814,6198,382,4217,9882	MAP2K5,SLC2A4,INPPL1,EGR1,MAP3K13,MTOR,RAF1,PRKAA1,FLOT1,MAP2K1,PIK3R4,RPS6KA5,MYO1C,MAP2K3,JUN,PTPN1,RPS6KA2,SHC1,SOCS1,CAP1,IKBKB,MAPK9,PIK3R2,PTPN11,SGK3,PRKCI,SGK1,GYS1,PIK3R3,MAP3K7,MAPK7,EIF4E,RPS6KB2,PDPK1,MAP3K3,PIK3C3,RHOQ,MAP2K7,GSK3A,AKT2,CBLB,SNAP25,STX4,ELK1,FOS,RHEB,TSC1,MAP2K6,MAPK6,XBP1,MAP3K11,SRF,GSK3B,STXBP3,RPS6KB1,ARF6,MAP3K5,TBC1D4
WP2032	TSH signaling pathway	0.0137995795572962	-4.2831171541457	64	26	0.0213815789473684	1216	4455	5170,673,1081,2475,1019,5894,5604,5900,2353,2773,7270,5606,3725,2768,5608,4609,5296,6194,6772,8458,1027,3717,6198,5144,6774,2771	PDPK1,BRAF,CGA,MTOR,CDK4,RAF1,MAP2K1,RALGDS,FOS,GNAI3,TTF1,MAP2K3,JUN,GNA12,MAP2K6,MYC,PIK3R2,RPS6,STAT1,TTF2,CDKN1B,JAK2,RPS6KB1,PDE4D,STAT3,GNAI2
WP2374	Oncostatin M Signaling Pathway	0.0214033691461183	-3.8442069326117	63	25	0.0205592105263158	1216	4455	1958,2475,5894,5604,7157,3845,6777,2353,7297,5581,840,6464,3491,3726,5601,6194,6772,5781,2185,9180,1027,3717,253260,6774,5970	EGR1,MTOR,RAF1,MAP2K1,TP53,KRAS,STAT5B,FOS,TYK2,PRKCE,CASP7,SHC1,CYR61,JUNB,MAPK9,RPS6,STAT1,PTPN11,PTK2B,OSMR,CDKN1B,JAK2,RICTOR,STAT3,RELA
WP2018	RANKL/RANK Signaling Pathway	0.0217109668715293	-3.82993776031535	54	22	0.0180921052631579	1216	4455	5609,2475,7186,208,5604,2274,1147,2353,3725,8517,8878,998,5608,3551,5601,5296,4286,5971,4791,6885,10454,5970	MAP2K7,MTOR,TRAF2,AKT2,MAP2K1,FHL2,CHUK,FOS,JUN,IKBKG,SQSTM1,CDC42,MAP2K6,IKBKB,MAPK9,PIK3R2,MITF,RELB,NFKB2,MAP3K7,TAB1,RELA
WP1601	Fluoropyrimidine Activity	0.0254375826604037	-3.67152756623556	34	15	0.0123355263157895	1216	4455	1890,7083,6996,2356,10257,5471,7378,7157,6240,6241,8836,7517,7372,2068,2030	TYMP,TK1,TDG,FPGS,ABCC4,PPAT,UPP1,TP53,RRM1,RRM2,GGH,XRCC3,UMPS,ERCC2,SLC29A1
WP2036	TWEAK Signaling Pathway	0.0270680055185882	-3.60940285673349	43	18	0.0148026315789474	1216	4455	330,7186,5894,208,1147,329,8772,3725,840,1499,3569,5601,3551,2932,5971,6885,4791,5970	BIRC3,TRAF2,RAF1,AKT2,CHUK,BIRC2,FADD,JUN,CASP7,CTNNB1,IL6,MAPK9,IKBKB,GSK3B,RELB,MAP3K7,NFKB2,RELA
WP28	Selenium Metabolism and Selenoproteins	0.0270680055185882	-3.60940285673349	43	18	0.0148026315789474	1216	4455	7296,85465,1734,6156,2353,54938,1390,6415,3725,140606,58515,51091,5970,4780,51540,2879,1491,6667	TXNRD1,EPT1,DIO2,RPL30,FOS,SARS2,CREM,SEPW1,JUN,SELM,SELK,SEPSECS,RELA,NFE2L2,SCLY,GPX4,CTH,SP1
WP2263	Prostate Cancer	0.0307560521466968	-3.48166848631693	109	39	0.0320723684210526	1216	4455	2475,5894,10397,5604,7157,1111,641,3725,1399,595,466,4609,4436,5781,581,545,253260,6774,10253,2956,6667,5058,993,10257,1019,842,3295,2002,2353,983,6009,572,7248,6772,2185,2289,6603,11200,86	MTOR,RAF1,NDRG1,MAP2K1,TP53,CHEK1,BLM,JUN,CRKL,CCND1,ATF1,MYC,MSH2,PTPN11,BAX,ATR,RICTOR,STAT3,SPRY2,MSH6,SP1,PAK1,CDC25A,ABCC4,CDK4,CASP9,HSD17B4,ELK1,FOS,CDK1,RHEB,BAD,TSC1,STAT1,PTK2B,FKBP5,SMARCD2,CHEK2,ACTL6A
WP2100	AhR pathway	0.0316627551835967	-3.45261420419699	29	13	0.0106907894736842	1216	4455	3725,3280,1728,581,1027,3320,10728,196,9049,405,4780,11140,1545	JUN,HES1,NQO1,BAX,CDKN1B,HSP90AA1,PTGES3,AHR,AIP,ARNT,NFE2L2,CDC37,CYP1B1
WP2203	TSLP Signaling Pathway	0.0340952838720559	-3.37859620712965	38	16	0.0131578947368421	1216	4455	2475,5604,6777,55361,4609,3569,6778,5601,6194,6772,5781,5971,3717,4791,5970,6774	MTOR,MAP2K1,STAT5B,PI4K2A,MYC,IL6,STAT6,MAPK9,RPS6,STAT1,PTPN11,RELB,JAK2,NFKB2,RELA,STAT3
WP2037	Prolactin Signaling Pathway	0.0359072975873192	-3.32681472873276	75	28	0.0230263157894737	1216	4455	5058,5479,2475,5894,5604,6777,2002,2353,5478,7532,3725,5770,6196,8651,6464,4609,5296,5601,5781,6194,3688,6772,2932,3717,7534,6198,6774,5970	PAK1,PPIB,MTOR,RAF1,MAP2K1,STAT5B,ELK1,FOS,PPIA,YWHAG,JUN,PTPN1,RPS6KA2,SOCS1,SHC1,MYC,PIK3R2,MAPK9,PTPN11,RPS6,ITGB1,STAT1,GSK3B,JAK2,YWHAZ,RPS6KB1,STAT3,RELA
WP288	NLR proteins	0.0392746407416826	-3.23717624213416	8	5	0.00411184210526316	1216	4455	8517,1147,55914,6885,3551	IKBKG,CHUK,ERBB2IP,MAP3K7,IKBKB
WP1541	Energy Metabolism	0.0428026103519226	-3.15115618872327	48	19	0.015625	1216	4455	23411,5564,64216,2551,5565,7351,5562,3276,5571,100271849,4205,4209,5467,51422,2932,23082,2101,10891,1386	SIRT1,PRKAB1,TFB2M,GABPA,PRKAB2,UCP2,PRKAA1,PRMT1,PRKAG1,MEF2B,MEF2A,MEF2D,PPARD,PRKAG2,GSK3B,PPRC1,ESRRA,PPARGC1A,ATF2
WP410	Diurnally regulated genes with circadian orthologs	0.0428026103519226	-3.15115618872327	48	19	0.015625	1216	4455	7360,3312,10946,3301,1982,5281,9709,11335,7341,8864,3108,694,3422,5187,406,51582,1408,9575,10381	UGP2,HSPA8,SF3A3,DNAJA1,EIF4G2,PIGF,HERPUD1,CBX3,SUMO1,PER2,HLA-DMA,BTG1,IDI1,PER1,ARNTL,AZIN1,CRY2,CLOCK,TUBB3
WP2525	Trans-sulfuration and one carbon metabolism	0.0552238596841309	-2.89636017843362	31	13	0.0106907894736842	1216	4455	27430,6470,10797,29968,2729,200895,10768,441024,4548,5723,23382,1491,2937	MAT2B,SHMT1,MTHFD2,PSAT1,GCLC,DHFRL1,AHCYL1,MTHFD2L,MTR,PSPH,AHCYL2,CTH,GSS
WP500	Glycogen Metabolism	0.0552684373469908	-2.89555328661444	37	15	0.0123355263157895	1216	4455	805,5529,2931,7360,5518,5837,5257,2997,5527,2932,5526,5521,5256,5528,5261	CALM2,PPP2R5E,GSK3A,UGP2,PPP2R1A,PYGM,PHKB,GYS1,PPP2R5C,GSK3B,PPP2R5B,PPP2R2B,PHKA2,PPP2R5D,PHKG2
WP1471	TOR signaling	0.0554137747643286	-2.8929270741798	34	14	0.0115131578947368	1216	4455	5564,7248,51422,998,2475,5565,5562,5571,6198,253260,84335,6009,64223,54541	PRKAB1,TSC1,PRKAG2,CDC42,MTOR,PRKAB2,PRKAA1,PRKAG1,RPS6KB1,RICTOR,AKT1S1,RHEB,MLST8,DDIT4
WP186	Homologous recombination	0.0591299539672909	-2.82801764764977	14	7	0.00575657894736842	1216	4455	5893,675,10714,5424,57804,5425,25788	RAD52,BRCA2,POLD3,POLD1,POLD4,POLD2,RAD54B
WP138	Androgen receptor signaling pathway	0.0612019821885494	-2.79357570128657	88	31	0.0254934210526316	1216	4455	23411,5883,90427,11143,11034,29893,2119,2274,64800,10399,857,7329,11315,5052,23028,7341,595,3725,811,8202,1499,998,1616,5296,6047,2932,6774,5970,9604,9475,6667	SIRT1,RAD9A,BMF,KAT7,DSTN,PSMC3IP,ETV5,FHL2,EFCAB6,GNB2L1,CAV1,UBE2I,PARK7,PRDX1,KDM1A,SUMO1,CCND1,JUN,CALR,NCOA3,CTNNB1,CDC42,DAXX,PIK3R2,RNF4,GSK3B,STAT3,RELA,RNF14,ROCK2,SP1
WP127	IL-5 Signaling Pathway	0.0641883576668041	-2.745933429485	69	25	0.0205592105263158	1216	4455	2931,5894,3845,6777,2002,3725,1399,6464,1499,8651,5296,5601,581,5781,6772,1785,1027,2185,2932,3717,7534,6386,5292,6774,1386	GSK3A,RAF1,KRAS,STAT5B,ELK1,JUN,CRKL,SHC1,CTNNB1,SOCS1,PIK3R2,MAPK9,BAX,PTPN11,STAT1,DNM2,CDKN1B,PTK2B,GSK3B,JAK2,YWHAZ,SDCBP,PIM1,STAT3,ATF2
WP1530	miRNA Regulation of DNA Damage Response	0.0688487255677029	-2.67584356425181	9	5	0.00411184210526316	1216	4455	84126,5981,55367,4176,4609	ATRIP,RFC1,PIDD1,MCM7,MYC
WP1971	Integrated Cancer pathway	0.0699645343785381	-2.65976681705931	35	14	0.0115131578947368	1216	4455	572,993,1019,842,7157,581,6772,4436,545,1111,11200,641,983,2956	BAD,CDC25A,CDK4,CASP9,TP53,BAX,STAT1,MSH2,ATR,CHEK1,CHEK2,BLM,CDK1,MSH6
WP422	MAPK Cascade	0.0707909131271987	-2.64802463218051	29	12	0.00986842105263158	1216	4455	4215,3725,673,5609,369,6237,5608,5894,5604,3845,2002,5606	MAP3K3,JUN,BRAF,MAP2K7,ARAF,RRAS,MAP2K6,RAF1,MAP2K1,KRAS,ELK1,MAP2K3
WP382	MAPK signaling pathway	0.0773807944960701	-2.55901666230228	163	53	0.0435855263157895	1216	4455	673,5607,1848,9175,4763,7186,5894,5604,7157,23162,3925,5495,5566,1847,1399,3725,998,4609,3551,5601,835,11221,5494,6885,5598,1386,1843,5058,627,468,5609,3164,208,3312,3309,842,8550,51295,3845,2002,2353,3304,2768,8517,840,1616,5608,5597,4296,6722,4217,10454,1649	BRAF,MAP2K5,DUSP6,MAP3K13,NF1,TRAF2,RAF1,MAP2K1,TP53,MAPK8IP3,STMN1,PPM1B,PRKACA,DUSP5,CRKL,JUN,CDC42,MYC,IKBKB,MAPK9,CASP2,DUSP10,PPM1A,MAP3K7,MAPK7,ATF2,DUSP1,PAK1,BDNF,ATF4,MAP2K7,NR4A1,AKT2,HSPA8,HSPA5,CASP9,MAPKAPK5,ECSIT,KRAS,ELK1,FOS,HSPA1B,GNA12,IKBKG,CASP7,DAXX,MAP2K6,MAPK6,MAP3K11,SRF,MAP3K5,TAB1,DDIT3
WP2380	BDNF signaling pathway	0.0872407116227877	-2.43908418061197	144	47	0.0386513157894737	1216	4455	6272,5607,1958,2475,5894,5562,5604,4205,324,6777,9252,3725,8894,1938,998,1499,6464,8878,6792,1808,5296,5601,5864,5781,6194,3717,4904,4082,5598,6774,1977,5970,5170,627,10451,6868,4690,10399,2002,2353,572,25970,6772,2185,2932,6198,4776	SORT1,MAP2K5,EGR1,MTOR,RAF1,PRKAA1,MAP2K1,MEF2A,APC,STAT5B,RPS6KA5,JUN,EIF2S2,EEF2,CDC42,CTNNB1,SHC1,SQSTM1,CDKL5,DPYSL2,PIK3R2,MAPK9,RAB3A,PTPN11,RPS6,JAK2,YBX1,MARCKS,MAPK7,STAT3,EIF4E,RELA,PDPK1,BDNF,VAV3,ADAM17,NCK1,GNB2L1,ELK1,FOS,BAD,SH2B1,STAT1,PTK2B,GSK3B,RPS6KB1,NFATC4
WP2035	FSH signaling pathway	0.0907148179109944	-2.4000345624266	27	11	0.00904605263157895	1216	4455	627,1081,2475,5894,6194,6446,6198,2870,5566,6009,6199	BDNF,CGA,MTOR,RAF1,RPS6,SGK1,RPS6KB1,GRK6,PRKACA,RHEB,RPS6KB2
WP528	Acetylcholine Synthesis	0.0935303978451564	-2.36946878488113	7	4	0.00328947368421053	1216	4455	5160,10400,5130,1119	PDHA1,PEMT,PCYT1A,CHKA
WP585	Interferon type I	0.0941405967536166	-2.36296590402757	49	18	0.0148026315789474	1216	4455	1975,2475,3276,10399,9252,7297,5606,6773,1399,8651,5608,5296,6772,5781,10379,6774,1977,64223	EIF4B,MTOR,PRMT1,GNB2L1,RPS6KA5,TYK2,MAP2K3,STAT2,CRKL,SOCS1,MAP2K6,PIK3R2,STAT1,PTPN11,IRF9,STAT3,EIF4E,MLST8
WP1772	Apoptosis Modulation and Signaling	0.105820289975911	-2.24601300123481	79	27	0.0222039473684211	1216	4455	90427,330,57448,8738,842,2021,56616,826,54205,598,2353,329,8772,572,8771,3725,840,332,1616,5366,3551,581,835,51651,4217,1029,51155	BMF,BIRC3,BIRC6,CRADD,CASP9,ENDOG,DIABLO,CAPNS1,CYCS,BCL2L1,FOS,BIRC2,FADD,BAD,TNFRSF6B,JUN,CASP7,BIRC5,DAXX,PMAIP1,IKBKB,BAX,CASP2,PTRH2,MAP3K5,CDKN2A,HN1
WP262	EBV LMP1 signaling	0.117705992133135	-2.13956535578974	22	9	0.00740131578947368	1216	4455	9260,4215,8517,3551,1147,3320,4791,6885,5970	PDLIM7,MAP3K3,IKBKG,IKBKB,CHUK,HSP90AA1,NFKB2,MAP3K7,RELA
WP734	Serotonin Receptor 4/6/7 and NR3C Signaling	0.118331894788145	-2.13426193496863	19	8	0.00657894736842105	1216	4455	466,673,1958,2908,5604,6722,2002,9252	ATF1,BRAF,EGR1,NR3C1,MAP2K1,SRF,ELK1,RPS6KA5
WP1991	SRF and miRs in Smooth Muscle Differentiation and Proliferation	0.118331894788145	-2.13426193496863	19	8	0.00657894736842105	1216	4455	817,100271849,6722,4205,4209,2002,1482,93649	CAMK2D,MEF2B,SRF,MEF2A,MEF2D,ELK1,NKX2-5,MYOCD
WP205	IL-7 Signaling Pathway	0.11916016548077	-2.12728676241051	44	16	0.0131578947368421	1216	4455	572,4582,890,6464,5894,1019,1213,581,6772,5604,868,2932,2185,6777,6774,8027	BAD,MUC1,CCNA2,SHC1,RAF1,CDK4,CLTC,BAX,STAT1,MAP2K1,CBLB,GSK3B,PTK2B,STAT5B,STAT3,STAM
WP2261	Signaling Pathways in Glioblastoma	0.119949315075318	-2.12068599979762	80	27	0.0222039473684211	1216	4455	1030,5170,673,5607,5609,4763,1019,5894,208,5604,7157,4194,3845,5606,595,7248,675,369,5608,5296,1027,2065,4233,1021,10253,1029,2956	CDKN2B,PDPK1,BRAF,MAP2K5,MAP2K7,NF1,CDK4,RAF1,AKT2,MAP2K1,TP53,MDM4,KRAS,MAP2K3,CCND1,TSC1,BRCA2,ARAF,MAP2K6,PIK3R2,CDKN1B,ERBB3,MET,CDK6,SPRY2,CDKN2A,MSH6
WP23	B Cell Receptor Signaling Pathway	0.124002083560246	-2.08745691061306	158	50	0.0411184210526316	1216	4455	673,1848,5966,4739,5894,10096,5604,1147,54205,1399,5581,3725,5164,890,1499,6464,3551,5296,5911,604,581,5781,6194,10097,6885,2969,6774,1386,5970,59339,1021,5170,2931,4690,1019,842,1796,868,8394,2002,10014,8396,8517,840,6772,3190,2185,2932,6198,10109	BRAF,DUSP6,REL,NEDD9,RAF1,ACTR3,MAP2K1,CHUK,CYCS,CRKL,PRKCE,JUN,PDK2,CCNA2,CTNNB1,SHC1,IKBKB,PIK3R2,RAP2A,BCL6,BAX,PTPN11,RPS6,ACTR2,MAP3K7,GTF2I,STAT3,ATF2,RELA,PLEKHA2,CDK6,PDPK1,GSK3A,NCK1,CDK4,CASP9,DOK1,CBLB,PIP5K1A,ELK1,HDAC5,PIP4K2B,IKBKG,CASP7,STAT1,HNRNPK,PTK2B,GSK3B,RPS6KB1,ARPC2
WP314	FAS pathway and Stress induction of HSP regulation	0.127573921667252	-2.05905930460749	38	14	0.0115131578947368	1216	4455	5058,3725,840,8767,4001,1616,7867,842,54205,6885,11124,8772,4000,6709	PAK1,JUN,CASP7,RIPK2,LMNB1,DAXX,MAPKAPK3,CASP9,CYCS,MAP3K7,FAF1,FADD,LMNA,SPTAN1
WP286	IL-3 Signaling Pathway	0.128197277423008	-2.05418497167109	104	34	0.0279605263157895	1216	4455	3397,5894,5604,6777,1111,598,5566,1399,466,6464,998,5296,5601,581,5781,3717,5598,6774,1386,7414,6199,5058,5914,2931,10971,3845,10399,7297,572,332,6778,6772,2932,7534	ID1,RAF1,MAP2K1,STAT5B,CHEK1,BCL2L1,PRKACA,CRKL,ATF1,SHC1,CDC42,PIK3R2,MAPK9,BAX,PTPN11,JAK2,MAPK7,STAT3,ATF2,VCL,RPS6KB2,PAK1,RARA,GSK3A,YWHAQ,KRAS,GNB2L1,TYK2,BAD,BIRC5,STAT6,STAT1,GSK3B,YWHAZ
WP259	Nifedipine Activity	0.129066446131539	-2.04742792094087	5	3	0.00246710526315789	1216	4455	2185,5111,5604	PTK2B,PCNA,MAP2K1
WP363	Wnt Signaling Pathway NetPath	0.139669783460068	-1.9684743320339	115	37	0.0304276315789474	1216	4455	3728,6908,5894,6929,324,1460,1488,2535,1452,7341,595,3725,1499,5300,5601,7020,30851,4040,6885,1856,8321,1454,607,2274,23401,1742,995,983,59343,260425,22943,80319,817,8607,10023,2932,8945	JUP,TBP,RAF1,TCF3,APC,CSNK2B,CTBP2,FZD2,CSNK1A1,SUMO1,CCND1,JUN,CTNNB1,PIN1,MAPK9,TFAP2A,TAX1BP3,LRP6,MAP3K7,DVL2,FZD1,CSNK1E,BCL9,FHL2,FRAT2,DLG4,CDC25C,CDK1,SENP2,MAGI3,DKK1,CXXC4,CAMK2D,RUVBL1,FRAT1,GSK3B,BTRC
WP1403	AMPK signaling	0.14045620984101	-1.96285951251816	68	23	0.0189144736842105	1216	4455	5564,5289,6517,2475,208,5565,5562,7157,79602,5209,5571,200186,7248,51422,890,1938,1994,5296,2997,8503,6198,6199,3156	PRKAB1,PIK3C3,SLC2A4,MTOR,AKT2,PRKAB2,PRKAA1,TP53,ADIPOR2,PFKFB3,PRKAG1,CRTC2,TSC1,PRKAG2,CCNA2,EEF2,ELAVL1,PIK3R2,GYS1,PIK3R3,RPS6KB1,RPS6KB2,HMGCR
WP49	IL-2 Signaling pathway	0.145704967115698	-1.92617147497087	42	15	0.0123355263157895	1216	4455	1399,3725,6464,5894,4609,5781,6772,5604,6194,2185,6198,6777,2353,6774,6199	CRKL,JUN,SHC1,RAF1,MYC,PTPN11,STAT1,MAP2K1,RPS6,PTK2B,RPS6KB1,STAT5B,FOS,STAT3,RPS6KB2
WP516	Hypertrophy Model	0.152172749555226	-1.88273889324295	20	8	0.00657894736842105	1216	4455	467,3475,27063,3491,1977,9948,11072,8013	ATF3,IFRD1,ANKRD1,CYR61,EIF4E,WDR1,DUSP14,NR4A3
WP712	Estrogen signaling pathway	0.152172749555226	-1.88273889324295	20	8	0.00657894736842105	1216	4455	3725,673,5601,5604,2002,5566,2353,6667	JUN,BRAF,MAPK9,MAP2K1,ELK1,PRKACA,FOS,SP1
WP364	IL-6 Signaling Pathway	0.153529493882474	-1.87386258785507	99	32	0.0263157894736842	1216	4455	3636,5894,5604,5526,3725,6196,6464,5518,5296,5781,6446,3717,2065,3320,5521,6885,6774,1977,842,2353,7297,572,5529,1616,5608,3569,6772,2185,5527,2932,6198,5528	INPPL1,RAF1,MAP2K1,PPP2R5B,JUN,RPS6KA2,SHC1,PPP2R1A,PIK3R2,PTPN11,SGK1,JAK2,ERBB3,HSP90AA1,PPP2R2B,MAP3K7,STAT3,EIF4E,CASP9,FOS,TYK2,BAD,PPP2R5E,DAXX,MAP2K6,IL6,STAT1,PTK2B,PPP2R5C,GSK3B,RPS6KB1,PPP2R5D
WP254	Apoptosis	0.168967217696391	-1.77805056100312	83	27	0.0222039473684211	1216	4455	330,8738,7186,27242,842,7157,665,56616,1147,54205,598,837,329,8772,572,3725,8517,840,332,5366,4609,3551,581,835,3660,5970,1029	BIRC3,CRADD,TRAF2,TNFRSF21,CASP9,TP53,BNIP3L,DIABLO,CHUK,CYCS,BCL2L1,CASP4,BIRC2,FADD,BAD,JUN,IKBKG,CASP7,BIRC5,PMAIP1,MYC,IKBKB,BAX,CASP2,IRF2,RELA,CDKN2A
WP2359	Parkin-Ubiquitin Proteasomal System pathway	0.171230995491213	-1.7647417832318	73	24	0.0197368421052632	1216	4455	7317,10383,3309,5702,3312,5713,5710,5715,3304,6622,3313,5707,3308,5719,5709,5714,51465,5717,25897,9861,5705,5700,203068,10381	UBA1,TUBB4B,HSPA5,PSMC3,HSPA8,PSMD7,PSMD4,PSMD9,HSPA1B,SNCA,HSPA9,PSMD1,HSPA4,PSMD13,PSMD3,PSMD8,UBE2J1,PSMD11,RNF19A,PSMD6,PSMC5,PSMC1,TUBB,TUBB3
WP2332	Interleukin-11 Signaling Pathway	0.177448171884384	-1.72907670208762	40	14	0.0115131578947368	1216	4455	5170,466,332,5894,3551,5296,5781,6772,6194,3717,1147,6774,5970,7297	PDPK1,ATF1,BIRC5,RAF1,IKBKB,PIK3R2,PTPN11,STAT1,RPS6,JAK2,CHUK,STAT3,RELA,TYK2
WP619	Type II interferon signaling (IFNG)	0.180078406498532	-1.71436293127592	50	17	0.0139802631578947	1216	4455	8362,8651,8367,8364,10379,5781,6772,6890,3660,3717,8363,8368,3459,2537,8360,6773,8365	HIST1H4K,SOCS1,HIST1H4E,HIST1H4C,IRF9,PTPN11,STAT1,TAP1,IRF2,JAK2,HIST1H4J,HIST1H4L,IFNGR1,IFI6,HIST1H4D,STAT2,HIST1H4H
WP26	Signal Transduction of S1P Receptor	0.183253970715948	-1.69688227015028	24	9	0.00740131578947368	1216	4455	208,5597,427,29127,9294,5598,2773,2771,56848	AKT2,MAPK6,ASAH1,RACGAP1,S1PR2,MAPK7,GNAI3,GNAI2,SPHK2
WP304	Kit Receptor Signaling Pathway	0.186159401582129	-1.68115197452846	67	22	0.0180921052631579	1216	4455	161742,200734,5894,1796,5604,868,6777,30011,572,1399,6464,8651,5296,4286,1213,2886,5781,6772,122809,3717,6774,9655	SPRED1,SPRED2,RAF1,DOK1,MAP2K1,CBLB,STAT5B,SH3KBP1,BAD,CRKL,SHC1,SOCS1,PIK3R2,MITF,CLTC,GRB7,PTPN11,STAT1,SOCS4,JAK2,STAT3,SOCS5
WP673	ErbB signaling pathway	0.196296583663706	-1.62812858150014	54	18	0.0148026315789474	1216	4455	5609,5163,2475,4690,5604,7157,3845,2002,572,3725,595,369,4609,2932,1027,6198,145957,2065	MAP2K7,PDK1,MTOR,NCK1,MAP2K1,TP53,KRAS,ELK1,BAD,JUN,CCND1,ARAF,MYC,GSK3B,CDKN1B,RPS6KB1,NRG4,ERBB3
WP391	Mitochondrial Gene Expression	0.208245547290721	-1.56903737972093	12	5	0.00411184210526316	1216	4455	3054,2101,10891,64216,6667	HCFC1,ESRRA,PPARGC1A,TFB2M,SP1
WP615	Senescence and Autophagy	0.213842307088215	-1.54251641835719	106	33	0.0271381578947368	1216	4455	673,7405,2335,2475,5894,5604,7157,26156,84335,8678,27173,5606,3725,5111,11337,8878,64422,1027,9776,4297,64223,3920,3621,5289,55054,9140,23710,3569,10533,2932,3159,9474,1029	BRAF,UVRAG,FN1,MTOR,RAF1,MAP2K1,TP53,RSL1D1,AKT1S1,BECN1,SLC39A1,MAP2K3,JUN,PCNA,GABARAP,SQSTM1,ATG3,CDKN1B,ATG13,KMT2A,MLST8,LAMP2,ING1,PIK3C3,ATG16L1,ATG12,GABARAPL1,IL6,ATG7,GSK3B,HMGA1,ATG5,CDKN2A
WP170	Nuclear Receptors	0.21511991460514	-1.53655966398544	38	13	0.0106907894736842	1216	4455	7421,5915,5467,5914,2908,3164,4929,10062,2100,2101,7376,7025,6257	VDR,RARB,PPARD,RARA,NR3C1,NR4A1,NR4A2,NR1H3,ESR2,ESRRA,NR1H2,NR2F1,RXRB
WP710	DNA damage response (only ATM dependent)	0.260154042593945	-1.34648135189339	91	28	0.0230263157894737	1216	4455	3146,5163,208,7157,324,572,3725,595,5529,6464,1499,998,5366,10023,80326,4609,5601,581,604,1027,2932,5527,6885,4791,8061,1856,1029,901	HMGB1,PDK1,AKT2,TP53,APC,BAD,JUN,CCND1,PPP2R5E,SHC1,CTNNB1,CDC42,PMAIP1,FRAT1,WNT10A,MYC,MAPK9,BAX,BCL6,CDKN1B,GSK3B,PPP2R5C,MAP3K7,NFKB2,FOSL1,DVL2,CDKN2A,CCNG2
WP581	EPO Receptor Signaling	0.261344417020331	-1.34191613613161	26	9	0.00740131578947368	1216	4455	5163,6464,8651,5894,6772,5604,6777,3717,6774	PDK1,SHC1,SOCS1,RAF1,STAT1,MAP2K1,STAT5B,JAK2,STAT3
WP428	Wnt Signaling Pathway	0.263601743417569	-1.3333158625002	60	19	0.015625	1216	4455	1454,324,2535,5581,3725,595,5529,1499,80326,4609,10023,5601,5584,2932,5527,26190,8061,1856,8321	CSNK1E,APC,FZD2,PRKCE,JUN,CCND1,PPP2R5E,CTNNB1,WNT10A,MYC,FRAT1,MAPK9,PRKCI,GSK3B,PPP2R5C,FBXW2,FOSL1,DVL2,FZD1
WP313	Signaling of Hepatocyte Growth Factor Receptor	0.272918540778297	-1.29858191375045	33	11	0.00904605263157895	1216	4455	1399,5058,3725,5894,5781,5604,3688,2185,2002,2353,6774	CRKL,PAK1,JUN,RAF1,PTPN11,MAP2K1,ITGB1,PTK2B,ELK1,FOS,STAT3
WP2333	Trans-sulfuration pathway	0.27983856717864	-1.27354238786989	10	4	0.00328947368421053	1216	4455	27430,2805,4548,1491	MAT2B,GOT1,MTR,CTH
WP2113	Type III interferon signaling	0.27983856717864	-1.27354238786989	10	4	0.00328947368421053	1216	4455	7297,6773,10379,6772	TYK2,STAT2,IRF9,STAT1
WP2038	Regulation of Microtubule Cytoskeleton	0.29979198741124	-1.20466642011763	44	14	0.0115131578947368	1216	4455	5058,90102,161742,998,1808,2932,10420,324,9212,11004,6774,5566,3925,983	PAK1,PHLDB2,SPRED1,CDC42,DPYSL2,GSK3B,TESK2,APC,AURKB,KIF2C,STAT3,PRKACA,STMN1,CDK1
WP733	Serotonin Receptor 2 and STAT3 Signaling	0.300947587503587	-1.20081915729034	4	2	0.00164473684210526	1216	4455	3717,6774	JAK2,STAT3
WP2253	pilocytic astrocytoma	0.300947587503587	-1.20081915729034	4	2	0.00164473684210526	1216	4455	4763,5781	NF1,PTPN11
WP690	Polyol pathway	0.300947587503587	-1.20081915729034	4	2	0.00164473684210526	1216	4455	231,6652	AKR1B1,SORD
WP2447	Amyotrophic lateral sclerosis (ALS)	0.310977067297367	-1.1680361081154	34	11	0.00904605263157895	1216	4455	79139,572,1616,5608,842,7157,581,5868,598,4217,57679	DERL1,BAD,DAXX,MAP2K6,CASP9,TP53,BAX,RAB5A,BCL2L1,MAP3K5,ALS2
WP2355	Corticotropin-releasing hormone	0.317122868522322	-1.14846598233929	90	27	0.0222039473684211	1216	4455	673,3728,3164,5894,842,5604,2870,2355,2002,2353,10155,2783,1499,3726,2354,5601,7020,5584,2932,4929,3320,1889,4217,8061,2771,5970,6667	BRAF,JUP,NR4A1,RAF1,CASP9,MAP2K1,GRK6,FOSL2,ELK1,FOS,TRIM28,GNB2,CTNNB1,JUNB,FOSB,MAPK9,TFAP2A,PRKCI,GSK3B,NR4A2,HSP90AA1,ECE1,MAP3K5,FOSL1,GNAI2,RELA,SP1
WP2272	Pathogenic Escherichia coli infection	0.318989759398233	-1.14259627891248	55	17	0.0139802631578947	1216	4455	4690,10383,10971,4691,10552,1499,998,8976,3688,9181,7534,2017,10109,3875,9475,203068,10381	NCK1,TUBB4B,YWHAQ,NCL,ARPC1A,CTNNB1,CDC42,WASL,ITGB1,ARHGEF2,YWHAZ,CTTN,ARPC2,KRT18,ROCK2,TUBB,TUBB3
WP22	IL-9 Signaling Pathway	0.321636428885994	-1.13433347419309	24	8	0.00657894736842105	1216	4455	6777,6464,6774,7297,7415,5781,6772,5604	STAT5B,SHC1,STAT3,TYK2,VCP,PTPN11,STAT1,MAP2K1
WP1528	Physiological and Pathological Hypertrophy  of the Heart	0.321636428885994	-1.13433347419309	24	8	0.00657894736842105	1216	4455	3725,5581,817,4776,6774,2353,5606,1906	JUN,PRKCE,CAMK2D,NFATC4,STAT3,FOS,MAP2K3,EDN1
WP53	Id Signaling Pathway	0.334347136347173	-1.09557549535456	52	16	0.0131578947368421	1216	4455	6938,3280,7050,3397,659,6929,3398,467,5710,2002,654,6934,890,1499,5933,5970	TCF12,HES1,TGIF1,ID1,BMPR2,TCF3,ID2,ATF3,PSMD4,ELK1,BMP6,TCF7L2,CCNA2,CTNNB1,RBL1,RELA
WP395	IL-4 signaling Pathway	0.348582688745919	-1.05387980649268	63	19	0.015625	1216	4455	598,2002,7297,8027,572,8651,6464,6778,5296,5584,6772,5781,653604,3717,6198,3159,5970,1386,9655	BCL2L1,ELK1,TYK2,STAM,BAD,SOCS1,SHC1,STAT6,PIK3R2,PRKCI,STAT1,PTPN11,HIST2H3D,JAK2,RPS6KB1,HMGA1,RELA,ATF2,SOCS5
WP1434	Osteopontin Signaling	0.35143158706641	-1.04574021806458	11	4	0.00328947368421053	1216	4455	1147,5970,3551,5604	CHUK,RELA,IKBKB,MAP2K1
WP268	Notch Signaling Pathway	0.368437635253208	-0.998483821151051	46	14	0.0115131578947368	1216	4455	3280,9253,51763,6868,51107,23220,1488,3516,9794,5663,23385,3066,8650,1856	HES1,NUMBL,INPP5K,ADAM17,APH1A,DTX4,CTBP2,RBPJ,MAML1,PSEN1,NCSTN,HDAC2,NUMB,DVL2
WP1433	NOD pathway	0.369746006310729	-0.994938978502356	39	12	0.00986842105263158	1216	4455	10910,8517,840,22900,8767,3551,842,1147,3320,639,55914,5970	SUGT1,IKBKG,CASP7,CARD8,RIPK2,IKBKB,CASP9,CHUK,HSP90AA1,PRDM1,ERBB2IP,RELA
WP408	Oxidative Stress	0.37017921965896	-0.99376801316011	32	10	0.00822368421052632	1216	4455	7296,1728,2729,3726,4128,4501,25828,2353,4780,6667	TXNRD1,NQO1,GCLC,JUNB,MAOA,MT1X,TXN2,FOS,NFE2L2,SP1
WP134	Pentose Phosphate Pathway	0.379301240495593	-0.969424559805963	8	3	0.00246710526315789	1216	4455	25796,22934,5226	PGLS,RPIA,PGD
WP69	TCR Signaling Pathway	0.379812513520939	-0.96807753348758	89	26	0.0213815789473684	1216	4455	5170,5058,10451,8767,4690,5966,5894,5604,10892,868,1147,2353,3725,1399,8517,998,6464,3569,5296,5601,3551,5781,2185,6885,5970,1386	PDPK1,PAK1,VAV3,RIPK2,NCK1,REL,RAF1,MAP2K1,MALT1,CBLB,CHUK,FOS,JUN,CRKL,IKBKG,CDC42,SHC1,IL6,PIK3R2,MAPK9,IKBKB,PTPN11,PTK2B,MAP3K7,RELA,ATF2
WP399	Wnt Signaling Pathway and Pluripotency	0.410590284064129	-0.890159437453383	101	29	0.0238486842105263	1216	4455	1454,7157,324,29127,1488,2535,6934,595,5581,3725,5467,5529,1499,5518,10023,80326,4609,5601,5584,2932,5527,26190,4040,1500,5521,6885,8061,1856,8321	CSNK1E,TP53,APC,RACGAP1,CTBP2,FZD2,TCF7L2,CCND1,PRKCE,JUN,PPARD,PPP2R5E,CTNNB1,PPP2R1A,FRAT1,WNT10A,MYC,MAPK9,PRKCI,GSK3B,PPP2R5C,FBXW2,LRP6,CTNND1,PPP2R2B,MAP3K7,FOSL1,DVL2,FZD1
WP1742	TP53 network	0.420808649630722	-0.865577062563804	19	6	0.00493421052631579	1216	4455	5366,4609,1029,7157,581,7341	PMAIP1,MYC,CDKN2A,TP53,BAX,SUMO1
WP384	Apoptosis Modulation by HSP70	0.420808649630722	-0.865577062563804	19	6	0.00493421052631579	1216	4455	54205,840,8772,842,3304,835	CYCS,CASP7,FADD,CASP9,HSPA1B,CASP2
WP1425	BMP signalling and regulation	0.423024606957667	-0.860324929151059	12	4	0.00328947368421053	1216	4455	659,4091,9241,10766	BMPR2,SMAD6,NOG,TOB2
WP1544	MicroRNAs in cardiomyocyte hypertrophy	0.429334662395975	-0.84551856534794	109	31	0.0254934210526316	1216	4455	5170,8893,5607,5609,2475,5894,208,1906,5604,1827,1147,2535,10014,5606,805,817,8517,9759,1499,5608,5296,3551,8503,4040,2932,4776,5598,6774,10454,9475,8321	PDPK1,EIF2B5,MAP2K5,MAP2K7,MTOR,RAF1,AKT2,EDN1,MAP2K1,RCAN1,CHUK,FZD2,HDAC5,MAP2K3,CALM2,CAMK2D,IKBKG,HDAC4,CTNNB1,MAP2K6,PIK3R2,IKBKB,PIK3R3,LRP6,GSK3B,NFATC4,MAPK7,STAT3,TAB1,ROCK2,FZD1
WP2324	AGE/RAGE pathway	0.438374682888439	-0.824681293901722	66	19	0.015625	1216	4455	5894,842,5604,6777,54205,1147,1729,3725,6464,1650,998,5601,3551,6772,3717,6774,1386,5970,6667	RAF1,CASP9,MAP2K1,STAT5B,CYCS,CHUK,DIAPH1,JUN,SHC1,DDOST,CDC42,MAPK9,IKBKB,STAT1,JAK2,STAT3,ATF2,RELA,SP1
WP561	Heme Biosynthesis	0.463483811517424	-0.768983821193674	9	3	0.00246710526315789	1216	4455	3145,210,5498	HMBS,ALAD,PPOX
WP2290	RalA downstream regulated genes	0.463483811517424	-0.768983821193674	9	3	0.00246710526315789	1216	4455	55770,998,10928	EXOC2,CDC42,RALBP1
WP61	Delta-Notch Signaling Pathway	0.463605353787968	-0.76872161929166	85	24	0.0197368421052632	1216	4455	3280,6868,51107,6929,6502,7157,9541,25942,5663,6015,3725,9253,5296,2932,3717,2273,3516,9794,6774,5970,23385,3066,8650,8819	HES1,ADAM17,APH1A,TCF3,SKP2,TP53,CIR1,SIN3A,PSEN1,RING1,JUN,NUMBL,PIK3R2,GSK3B,JAK2,FHL1,RBPJ,MAML1,STAT3,RELA,NCSTN,HDAC2,NUMB,SAP30
WP1495	Glycine Metabolism	0.471445382321702	-0.751952021748385	2	1	0.000822368421052632	1216	4455	6470	SHMT1
WP2112	IL17 signaling pathway	0.481556597115222	-0.730731511317838	31	9	0.00740131578947368	1216	4455	8517,3551,2932,3717,6885,10758,5970,6774,6667	IKBKG,IKBKB,GSK3B,JAK2,MAP3K7,TRAF3IP2,RELA,STAT3,SP1
WP3	Keap1-Nrf2 Pathway	0.492442281883384	-0.708378019383176	13	4	0.00328947368421053	1216	4455	1728,7965,2729,4780	NQO1,AIMP2,GCLC,NFE2L2
WP2371	Parkinsons Disease Pathway	0.510002034484735	-0.673340564085968	39	11	0.00904605263157895	1216	4455	2058,840,7317,6311,842,51465,835,54205,7314,11315,6622	EPRS,CASP7,UBA1,ATXN2,CASP9,UBE2J1,CASP2,CYCS,UBB,PARK7,SNCA
WP438	Non-homologous end joining	0.519693699264021	-0.654515680835691	6	2	0.00164473684210526	1216	4455	2547,7520	XRCC6,XRCC5
WP1422	Sphingolipid Metabolism	0.530264799812368	-0.63437877491814	21	6	0.00493421052631579	1216	4455	427,57515,10558,56848,9517,91012	ASAH1,SERINC1,SPTLC1,SPHK2,SPTLC2,CERS5
WP524	G13 Signaling Pathway	0.548685686179933	-0.600229522044547	40	11	0.00904605263157895	1216	4455	805,998,11113,8976,9138,5296,5500,6198,1729,9475,6242	CALM2,CDC42,CIT,WASL,ARHGEF1,PIK3R2,PPP1CB,RPS6KB1,DIAPH1,ROCK2,RTKN
WP357	Fatty Acid Biosynthesis	0.581686256061448	-0.541824055538208	22	6	0.00493421052631579	1216	4455	3033,5091,55862,1891,47,51102	HADH,PC,ECHDC1,ECH1,ACLY,MECR
WP1310	Selenium	0.610577945599566	-0.493349318561375	7	2	0.00164473684210526	1216	4455	7296,6415	TXNRD1,SEPW1
WP1272	Selenium	0.610577945599566	-0.493349318561375	7	2	0.00164473684210526	1216	4455	6415,7296	SEPW1,TXNRD1
WP678	Arachidonate Epoxygenase / Epoxide Hydrolase	0.610577945599566	-0.493349318561375	7	2	0.00164473684210526	1216	4455	9377,1351	COX5A,COX8A
WP136	Phase I, non P450	0.610577945599566	-0.493349318561375	7	2	0.00164473684210526	1216	4455	5445,3988	PON2,LIPA
WP1423	Ganglio Sphingolipid Metabolism	0.61372291467108	-0.488211731729353	11	3	0.00246710526315789	1216	4455	6483,8705,9197	ST3GAL2,B3GALT4,SLC33A1
WP35	G Protein Signaling Pathways	0.624594613020844	-0.470652458856801	95	25	0.0205592105263158	1216	4455	10142,5141,6237,2788,3845,5151,27115,5566,2773,2783,8165,805,5581,2768,9138,10270,5150,5584,6548,51764,5144,2771,2787,11216,5573	AKAP9,PDE4A,RRAS,GNG7,KRAS,PDE8A,PDE7B,PRKACA,GNAI3,GNB2,AKAP1,CALM2,PRKCE,GNA12,ARHGEF1,AKAP8,PDE7A,PRKCI,SLC9A1,GNG13,PDE4D,GNAI2,GNG5,AKAP10,PRKAR1A
WP244	Alpha6-Beta4 Integrin Signaling Pathway	0.635038021079649	-0.454070406165943	69	18	0.0148026315789474	1216	4455	5058,2475,10971,55914,5339,7531,1832,3921,3914,6242,572,6464,5296,8503,7534,4233,7533,1977	PAK1,MTOR,YWHAQ,ERBB2IP,PLEC,YWHAE,DSP,RPSA,LAMB3,RTKN,BAD,SHC1,PIK3R2,PIK3R3,YWHAZ,MET,YWHAH,EIF4E
WP497	Urea cycle and metabolism of amino groups	0.673713495971945	-0.394950338602332	20	5	0.00411184210526316	1216	4455	384,1373,5832,65263,6611	ARG2,CPS1,ALDH18A1,PYCRL,SMS
WP2007	Iron metabolism in placenta	0.677289017247645	-0.389657188384195	12	3	0.00246710526315789	1216	4455	4891,3658,7037	SLC11A2,IREB2,TFRC
WP34	Ovarian Infertility Genes	0.679842322659453	-0.385894386141928	32	8	0.00657894736842105	1216	4455	7421,1027,4439,4292,2100,1958,1019,6609	VDR,CDKN1B,MSH5,MLH1,ESR2,EGR1,CDK4,SMPD1
WP185	Integrin-mediated cell adhesion	0.713612049788403	-0.337415811944661	99	25	0.0205592105263158	1216	4455	5170,5058,10451,673,5607,7094,5894,208,5604,826,857,9815,5606,7791,7408,6464,998,369,5608,5597,5296,3688,5598,7414,9475	PDPK1,PAK1,VAV3,BRAF,MAP2K5,TLN1,RAF1,AKT2,MAP2K1,CAPNS1,CAV1,GIT2,MAP2K3,ZYX,VASP,SHC1,CDC42,ARAF,MAP2K6,MAPK6,PIK3R2,ITGB1,MAPK7,VCL,ROCK2
WP241	One Carbon Metabolism	0.71555658562141	-0.334694597687967	29	7	0.00575657894736842	1216	4455	27430,2618,10797,6470,4548,23382,4552	MAT2B,GART,MTHFD2,SHMT1,MTR,AHCYL2,MTRR
WP1038	Vitamin A and Carotenoid Metabolism	0.716278410988526	-0.333686345438268	25	6	0.00493421052631579	1216	4455	53630,5915,5914,6820,157506,6257	BCO1,RARB,RARA,SULT2B1,RDH10,RXRB
WP1584	Type II diabetes mellitus	0.718541213528326	-0.330532214595477	21	5	0.00411184210526316	1216	4455	2710,6517,2475,3551,122809	GK,SLC2A4,MTOR,IKBKB,SOCS4
WP534	Glycolysis and Gluconeogenesis	0.721837147277292	-0.325955723318979	49	12	0.00986842105263158	1216	4455	5160,2597,6517,5091,5230,4191,226,3939,5105,5224,2805,1738	PDHA1,GAPDH,SLC2A4,PC,PGK1,MDH2,ALDOA,LDHA,PCK1,PGAM2,GOT1,DLD
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling	0.723346791085186	-0.323866516101923	17	4	0.00328947368421053	1216	4455	6722,2002,5894,5604	SRF,ELK1,RAF1,MAP2K1
WP2436	Dopamine metabolism	0.732743037861303	-0.310960200819688	13	3	0.00246710526315789	1216	4455	4128,1728,5566	MAOA,NQO1,PRKACA
WP98	Prostaglandin Synthesis and Regulation	0.750733026647425	-0.286705180902512	30	7	0.00575657894736842	1216	4455	306,5743,302,6281,6277,5734,1906	ANXA3,PTGS2,ANXA2,S100A10,S100A6,PTGER4,EDN1
WP696	Benzo(a)pyrene metabolism	0.751723428955955	-0.285386803323862	9	2	0.00164473684210526	1216	4455	10327,1545	AKR1A1,CYP1B1
WP289	Myometrial Relaxation and Contraction Pathways	0.755516078033611	-0.280354216180616	155	39	0.0320723684210526	1216	4455	6004,1388,2870,5997,7531,5566,2783,2553,22809,805,5581,3725,466,488,800,51764,8490,1265,5144,1386,2787,6667,468,2551,10287,2788,10971,467,2353,7532,817,2114,3569,59345,7534,784,7533,23764,5573	RGS16,ATF6B,GRK6,RGS2,YWHAE,PRKACA,GNB2,GABPB1,ATF5,CALM2,PRKCE,JUN,ATF1,ATP2A2,CALD1,GNG13,RGS5,CNN2,PDE4D,ATF2,GNG5,SP1,ATF4,GABPA,RGS19,GNG7,YWHAQ,ATF3,FOS,YWHAG,CAMK2D,ETS2,IL6,GNB4,YWHAZ,CACNB3,YWHAH,MAFF,PRKAR1A
WP47	Hedgehog Signaling Pathway	0.758792671606427	-0.27602669884031	22	5	0.00411184210526316	1216	4455	10284,1859,25942,983,2735	SAP18,DYRK1A,SIN3A,CDK1,GLI1
WP560	TGF Beta Signaling Pathway	0.774962311195169	-0.254940881527212	55	13	0.0106907894736842	1216	4455	3725,6498,7050,4052,1499,7030,5601,9241,6772,4092,2353,4091,6774	JUN,SKIL,TGIF1,LTBP1,CTNNB1,TFE3,MAPK9,NOG,STAT1,SMAD7,FOS,SMAD6,STAT3
WP688	Catalytic cycle of mammalian FMOs	0.797021553815779	-0.226873556874059	5	1	0.000822368421052632	1216	4455	2329	FMO4
WP325	Triacylglyceride Synthesis	0.826007093482151	-0.191151917747245	24	5	0.00411184210526316	1216	4455	2710,57678,10555,56895,10554	GK,GPAM,AGPAT2,AGPAT4,AGPAT1
WP176	Folate Metabolism	0.826007093482151	-0.191151917747245	24	5	0.00411184210526316	1216	4455	55312,4791,5970,2879,4552	RFK,NFKB2,RELA,GPX4,MTRR
WP465	Tryptophan metabolism	0.845739661162004	-0.167543695857163	46	10	0.00822368421052632	1216	4455	3033,8942,1718,3276,4967,2639,51366,224,1545,7453	HADH,KYNU,DHCR24,PRMT1,OGDH,GCDH,UBR5,ALDH3A2,CYP1B1,WARS
WP2012	miRs in Muscle Cell Differentiation	0.849492404035423	-0.163116279598859	42	9	0.00740131578947368	1216	4455	5581,5584,6722,100271849,3398,4205,4209,5566,5573	PRKCE,PRKCI,SRF,MEF2B,ID2,MEF2A,MEF2D,PRKACA,PRKAR1A
WP2059	Alzheimers Disease	0.850219394220344	-0.162260851955185	79	18	0.0148026315789474	1216	4455	6868,2597,51107,842,7157,9451,54205,5663,8772,6622,805,572,840,3416,488,2932,22926,23385	ADAM17,GAPDH,APH1A,CASP9,TP53,EIF2AK3,CYCS,PSEN1,FADD,SNCA,CALM2,BAD,CASP7,IDE,ATP2A2,GSK3B,ATF6,NCSTN
WP1981	Thyroxine (Thyroid Hormone) Production	0.852487124740175	-0.159597172882592	6	1	0.000822368421052632	1216	4455	1081	CGA
WP236	Adipogenesis	0.852735481216282	-0.159305883666749	131	31	0.0254934210526316	1216	4455	4282,5914,6517,2908,100271849,6777,4205,4209,64900,10062,6773,4000,7025,10269,5467,1499,10555,8651,5933,3569,6778,4616,6772,5105,3159,10891,6774,196,1649,6667,8321	MIF,RARA,SLC2A4,NR3C1,MEF2B,STAT5B,MEF2A,MEF2D,LPIN3,NR1H3,STAT2,LMNA,NR2F1,ZMPSTE24,PPARD,CTNNB1,AGPAT2,SOCS1,RBL1,IL6,STAT6,GADD45B,STAT1,PCK1,HMGA1,PPARGC1A,STAT3,AHR,DDIT3,SP1,FZD1
WP2328	Allograft Rejection	0.854197549806021	-0.157592788986727	38	8	0.00657894736842105	1216	4455	3122,3108,3592,3107,3134,3133,3105,3109	HLA-DRA,HLA-DMA,IL12A,HLA-C,HLA-F,HLA-E,HLA-A,HLA-DMB
WP2291	Deregulation of Rab and Rab Effector Genes in Bladder Cancer	0.85466186666469	-0.157049365852419	16	3	0.00246710526315789	1216	4455	201294,9648,5874	UNC13D,GCC2,RAB27B
WP2197	Endothelin	0.860113814165916	-0.15069055643763	34	7	0.00575657894736842	1216	4455	805,51764,1889,488,5894,5604,1906	CALM2,GNG13,ECE1,ATP2A2,RAF1,MAP2K1,EDN1
WP143	Fatty Acid Beta Oxidation	0.860113814165916	-0.15069055643763	34	7	0.00575657894736842	1216	4455	2710,3033,2639,1738,1632,2820,3032	GK,HADH,GCDH,DLD,ECI1,GPD2,HADHB
WP106	Alanine and aspartate metabolism	0.880239769776271	-0.127560942967057	12	2	0.00164473684210526	1216	4455	2805,5091	GOT1,PC
WP694	Arylamine metabolism	0.892805321260722	-0.113386727179391	7	1	0.000822368421052632	1216	4455	9	NAT1
WP666	Hypothetical Network for Drug Addiction	0.905630544632947	-0.0991238434878955	32	6	0.00493421052631579	1216	4455	54386,5581,22882,5566,5604,889	TERF2IP,PRKCE,ZHX2,PRKACA,MAP2K1,KRIT1
WP2276	Glial Cell Differentiation	0.922110341351657	-0.0810903864997593	8	1	0.000822368421052632	1216	4455	1267	CNP
WP1531	Vitamin D synthesis	0.922110341351657	-0.0810903864997593	8	1	0.000822368421052632	1216	4455	7421	VDR
WP1533	Vitamin B12 Metabolism	0.924918931741466	-0.0780491866710173	19	3	0.00246710526315789	1216	4455	4791,5970,4552	NFKB2,RELA,MTRR
WP1449	Regulation of toll-like receptor signaling pathway	0.925858429335697	-0.0770339401106408	102	22	0.0180921052631579	1216	4455	5609,208,5604,1147,2353,5606,8772,3725,3592,8517,5608,3569,3551,5601,5296,6772,8503,4791,6885,10454,5970,64223	MAP2K7,AKT2,MAP2K1,CHUK,FOS,MAP2K3,FADD,JUN,IL12A,IKBKG,MAP2K6,IL6,IKBKB,MAPK9,PIK3R2,STAT1,PIK3R3,NFKB2,MAP3K7,TAB1,RELA,MLST8
WP1591	Heart Development	0.9274599191755	-0.0753056992612449	47	9	0.00740131578947368	1216	4455	5308,659,1499,5781,6722,4776,2065,8553,1482	PITX2,BMPR2,CTNNB1,PTPN11,SRF,NFATC4,ERBB3,BHLHE40,NKX2-5
WP306	Focal Adhesion	0.931876071961388	-0.0705554431363509	184	42	0.0345394736842105	1216	4455	5753,673,5607,2335,4659,7094,5894,5604,30849,10420,329,5606,3914,595,3725,7791,7408,6464,998,53918,5601,5296,4637,4233,5598,7414,9475,5170,5058,330,208,87,857,2002,572,29780,369,5608,5597,3688,2932,1288	PTK6,BRAF,MAP2K5,FN1,PPP1R12A,TLN1,RAF1,MAP2K1,PIK3R4,TESK2,BIRC2,MAP2K3,LAMB3,CCND1,JUN,ZYX,VASP,SHC1,CDC42,PELO,MAPK9,PIK3R2,MYL6,MET,MAPK7,VCL,ROCK2,PDPK1,PAK1,BIRC3,AKT2,ACTN1,CAV1,ELK1,BAD,PARVB,ARAF,MAP2K6,MAPK6,ITGB1,GSK3B,COL4A6
WP75	Toll-like receptor signaling pathway	0.933565250240095	-0.0687444199534885	103	22	0.0180921052631579	1216	4455	5609,208,5604,1147,2353,8772,5606,3725,3592,8517,3569,5608,5296,5601,3551,6772,8503,6885,4791,5970,10454,100302736	MAP2K7,AKT2,MAP2K1,CHUK,FOS,FADD,MAP2K3,JUN,IL12A,IKBKG,IL6,MAP2K6,PIK3R2,MAPK9,IKBKB,STAT1,PIK3R3,MAP3K7,NFKB2,RELA,TAB1,TMED7-TICAM2
WP2118	Arrhythmogenic right ventricular cardiomyopathy	0.936857121293015	-0.0652244936503769	74	15	0.0123355263157895	1216	4455	59283,1499,488,2010,3728,1495,783,3688,5318,87,784,1832,1605,6934,4000	CACNG8,CTNNB1,ATP2A2,EMD,JUP,CTNNA1,CACNB2,ITGB1,PKP2,ACTN1,CACNB3,DSP,DAG1,TCF7L2,LMNA
WP15	Selenium Pathway	0.938957283262583	-0.0629852925417931	87	18	0.0148026315789474	1216	4455	7296,55163,85465,55312,1734,4548,5052,80308,6415,5743,3569,8942,140606,58515,4791,5970,1491,2879	TXNRD1,PNPO,EPT1,RFK,DIO2,MTR,PRDX1,FLAD1,SEPW1,PTGS2,IL6,KYNU,SELM,SELK,NFKB2,RELA,CTH,GPX4
WP167	Eicosanoid Synthesis	0.9403018759443	-0.0615543106523877	20	3	0.00246710526315789	1216	4455	5743,50640,80142	PTGS2,PNPLA8,PTGES2
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy	0.944690844285329	-0.0568975539176844	15	2	0.00164473684210526	1216	4455	6774,208	STAT3,AKT2
WP299	Nuclear receptors in lipid metabolism and toxicity	0.944916750524005	-0.056658450052551	35	6	0.00493421052631579	1216	4455	7421,5915,5467,5914,10062,5825	VDR,RARB,PPARD,RARA,NR1H3,ABCD3
WP716	Vitamin A and carotenoid metabolism	0.948200851923228	-0.0531889300508779	40	7	0.00575657894736842	1216	4455	5915,53630,5914,6820,9249,157506,6257	RARB,BCO1,RARA,SULT2B1,DHRS3,RDH10,RXRB
WP706	SIDS Susceptibility Pathways	0.953850521170764	-0.047248306214259	160	35	0.0287828947368421	1216	4455	4152,7184,1958,6929,10664,8553,7531,5566,7259,1390,3725,1499,3032,4904,1889,4791,4150,5316,6667,3280,627,2597,2908,10971,6616,2100,7532,3569,226,4128,7534,10891,7533,30012,5573	MBD1,HSP90B1,EGR1,TCF3,CTCF,BHLHE40,YWHAE,PRKACA,TSPYL1,CREM,JUN,CTNNB1,HADHB,YBX1,ECE1,NFKB2,MAZ,PKNOX1,SP1,HES1,BDNF,GAPDH,NR3C1,YWHAQ,SNAP25,ESR2,YWHAG,IL6,ALDOA,MAOA,YWHAZ,PPARGC1A,YWHAH,TLX3,PRKAR1A
WP368	Mitochondrial LC-Fatty Acid Beta-Oxidation	0.957552126810088	-0.0433751188764387	16	2	0.00164473684210526	1216	4455	3033,1632	HADH,ECI1
WP12	Osteoclast Signaling	0.957552126810088	-0.0433751188764387	16	2	0.00164473684210526	1216	4455	6548,7965	SLC9A1,AIMP2
WP496	Steroid Biosynthesis	0.958886666326995	-0.0419823900949072	10	1	0.000822368421052632	1216	4455	3295	HSD17B4
WP1455	Serotonin Transporter Activity	0.958886666326995	-0.0419823900949072	10	1	0.000822368421052632	1216	4455	4128	MAOA
WP51	Regulation of Actin Cytoskeleton	0.960045033122264	-0.0407750861181127	145	31	0.0254934210526316	1216	4455	10163,5058,54961,10152,5289,673,6237,2335,4659,8936,5894,5604,30849,87,324,3845,8394,4628,7114,2768,8396,55845,998,5597,9138,5296,8503,6548,138429,7414,9475	WASF2,PAK1,SSH3,ABI2,PIK3C3,BRAF,RRAS,FN1,PPP1R12A,WASF1,RAF1,MAP2K1,PIK3R4,ACTN1,APC,KRAS,PIP5K1A,MYH10,TMSB4X,GNA12,PIP4K2B,BRK1,CDC42,MAPK6,ARHGEF1,PIK3R2,PIK3R3,SLC9A1,PIP5KL1,VCL,ROCK2
WP2267	Synaptic Vesicle Pathway	0.961895688848782	-0.0388492657456792	51	9	0.00740131578947368	1216	4455	81539,160,1213,5864,1785,163,6616,1175,11315	SLC38A1,AP2A1,CLTC,RAB3A,DNM2,AP2B1,SNAP25,AP2S1,PARK7
WP100	Glutathione metabolism	0.962689096709837	-0.0380247680026285	22	3	0.00246710526315789	1216	4455	2729,2937,2879	GCLC,GSS,GPX4
WP2289	Drug Induction of Bile Acid Pathway	0.967518968854759	-0.0330202482189655	17	2	0.00164473684210526	1216	4455	7421,10257	VDR,ABCC4
WP554	ACE Inhibitor Pathway	0.967518968854759	-0.0330202482189655	17	2	0.00164473684210526	1216	4455	4306,10159	NR3C2,ATP6AP2
WP697	Estrogen metabolism	0.967518968854759	-0.0330202482189655	17	2	0.00164473684210526	1216	4455	1728,1545	NQO1,CYP1B1
WP530	Cytokines and Inflammatory Response	0.97065509892138	-0.0297840757246893	23	3	0.00246710526315789	1216	4455	3122,2920,3569	HLA-DRA,CXCL2,IL6
WP692	Sulfation Biotransformation Reaction	0.975211942600673	-0.0251004545809209	18	2	0.00164473684210526	1216	4455	6820,25830	SULT2B1,SULT4A1
WP247	Small Ligand GPCRs	0.981128767408443	-0.0190515666562347	19	2	0.00164473684210526	1216	4455	9294,5734	S1PR2,PTGER4
WP2064	Neural Crest Differentiation	0.982732976709454	-0.0174178369269107	101	19	0.015625	1216	4455	3280,3397,5376,1488,10013,6911,10014,4488,9759,1499,4609,4286,7020,3688,2932,3516,4791,3066,1856	HES1,ID1,PMP22,CTBP2,HDAC6,TBX6,HDAC5,MSX2,HDAC4,CTNNB1,MYC,MITF,TFAP2A,ITGB1,GSK3B,RBPJ,NFKB2,HDAC2,DVL2
WP229	Irinotecan Pathway	0.984243451156449	-0.0158820028187806	13	1	0.000822368421052632	1216	4455	324	APC
WP550	Biogenic Amine Synthesis	0.991690098918484	-0.00834462078818384	15	1	0.000822368421052632	1216	4455	4128	MAOA
WP501	GPCRs, Class C Metabotropic glutamate, pheromone	0.991690098918484	-0.00834462078818384	15	1	0.000822368421052632	1216	4455	55890	GPRC5C
WP474	Endochondral Ossification	0.992547258663033	-0.00748065177299332	65	10	0.00822368421052632	1216	4455	805,3157,50515,9759,579,6772,6777,871,5566,654	CALM2,HMGCS1,CHST11,HDAC4,NKX3-2,STAT1,STAT5B,SERPINH1,PRKACA,BMP6
WP334	GPCRs, Class B Secretin-like	0.993789126764918	-0.006230240943485	23	2	0.00164473684210526	1216	4455	976,30817	ADGRE5,ADGRE2
WP1539	Angiogenesis	0.993789126764918	-0.006230240943485	23	2	0.00164473684210526	1216	4455	405,284	ARNT,ANGPT1
WP545	Complement Activation, Classical Pathway	0.995618900906821	-0.00439072423055277	17	1	0.000822368421052632	1216	4455	1604	CD55
WP2431	Spinal Cord Injury	0.996613253288089	-0.00339249472025764	112	19	0.015625	1216	4455	4282,627,50515,1958,3164,1019,1875,7157,57142,2920,2353,57556,983,595,998,4609,3569,1027,9475	MIF,BDNF,CHST11,EGR1,NR4A1,CDK4,E2F5,TP53,RTN4,CXCL2,FOS,SEMA6A,CDK1,CCND1,CDC42,MYC,IL6,CDKN1B,ROCK2
WP430	Statin Pathway	0.996996200130142	-0.00300832033133061	32	3	0.00246710526315789	1216	4455	6646,2222,3156	SOAT1,FDFT1,HMGCR
WP536	Calcium Regulation in the Cardiac Cell	0.99702272705558	-0.00298171383820497	149	27	0.0222039473684211	1216	4455	6004,10287,2788,10971,154,2870,5997,7531,5566,2773,2783,7532,805,5581,811,817,488,59345,51764,7534,8490,483,784,2771,7533,2787,5573	RGS16,RGS19,GNG7,YWHAQ,ADRB2,GRK6,RGS2,YWHAE,PRKACA,GNAI3,GNB2,YWHAG,CALM2,PRKCE,CALR,CAMK2D,ATP2A2,GNB4,GNG13,YWHAZ,RGS5,ATP1B3,CACNB3,GNAI2,YWHAH,GNG5,PRKAR1A
WP698	Glucuronidation	0.997347818517124	-0.00265570474712116	26	2	0.00164473684210526	1216	4455	7360,7358	UGP2,UGDH
WP691	Tamoxifen metabolism	0.997691007053209	-0.00231166278154951	19	1	0.000822368421052632	1216	4455	1545	CYP1B1
WP58	Monoamine GPCRs	0.997692278120071	-0.00231038877382302	33	3	0.00246710526315789	1216	4455	154,3361,3269	ADRB2,HTR5A,HRH1
WP1602	Nicotine Activity on Dopaminergic Neurons	0.998783493915668	-0.00121724662850427	21	1	0.000822368421052632	1216	4455	5566	PRKACA
WP383	Striated Muscle Contraction	0.999396632963627	-0.000603549135515591	38	3	0.00246710526315789	1216	4455	7169,7170,7171	TPM2,TPM3,TPM4
WP1545	miRNAs involved in DDR	0.999792200202636	-0.000207821390732936	72	8	0.00657894736842105	1216	4455	595,993,4609,7157,3014,1027,5893,1021	CCND1,CDC25A,MYC,TP53,H2AFX,CDKN1B,RAD52,CDK6
WP43	cytochrome P450	0.999851588193932	-0.000148422820190301	62	6	0.00493421052631579	1216	4455	1595,10858,51167,1528,57404,1545	CYP51A1,CYP46A1,CYB5R4,CYB5A,CYP20A1,CYP1B1
WP453	Inflammatory Response Pathway	0.999932252585317	-6.77497096424409e-05	30	1	0.000822368421052632	1216	4455	2335	FN1
WP2406	Cardiac Progenitor Differentiation	0.999937865930466	-6.21359999352205e-05	53	4	0.00328947368421053	1216	4455	2932,1482,9241,22943	GSK3B,NKX2-5,NOG,DKK1
WP129	Matrix Metalloproteinases	0.99995086974174	-4.91314651902621e-05	31	1	0.000822368421052632	1216	4455	682	BSG
WP727	Monoamine Transport	0.999964373913162	-3.56267214619348e-05	32	1	0.000822368421052632	1216	4455	995	CDC25C
WP702	metapathway biotransformation	0.999999581842636	-4.18157451434062e-07	181	23	0.0189144736842105	1216	4455	57106,2954,26151,4837,50515,79829,10858,4259,25830,57404,55226,122830,2937,10327,1595,373156,119391,9,2329,231,6820,1545,2879	NAT14,GSTZ1,NAT9,NNMT,CHST11,NAA40,CYP46A1,MGST3,SULT4A1,CYP20A1,NAT10,NAA30,GSS,AKR1A1,CYP51A1,GSTK1,GSTO2,NAT1,FMO4,AKR1B1,SULT2B1,CYP1B1,GPX4
WP558	Complement and Coagulation Cascades	0.999999921950554	-7.80494486742496e-08	51	1	0.000822368421052632	1216	4455	2152	F3
WP24	Peptide GPCRs	0.999999997557071	-2.44292910668744e-09	72	2	0.00164473684210526	1216	4455	6755,10396	SSTR5,ATP8A1
WP455	GPCRs, Class A Rhodopsin-like	0.999999999942355	-5.76452897288004e-11	257	8	0.00657894736842105	1216	4455	6755,5734,23596,2827,2863,154,3361,3269	SSTR5,PTGER4,OPN3,GPR3,GPR39,ADRB2,HTR5A,HRH1
WP2516	ATM Signaling Pathway	0.999999999996873	-3.12679396263782e-12	3	0	0	1216	4455
WP2526	PDGF Pathway	0.999999999997444	-2.55577503605053e-12	2	0	0	1216	4455
WP1273	Folic Acid Network	0.999999999997444	-2.55577503605053e-12	2	0	0	1216	4455
WP1075	Folic Acid Network	0.999999999997444	-2.55577503605053e-12	2	0	0	1216	4455
WP1311	Folic Acid Network	0.999999999997444	-2.55577503605053e-12	2	0	0	1216	4455
WP311	Synthesis and Degradation of Ketone Bodies	0.999999999999003	-9.96763435678893e-13	5	0	0	1216	4455
WP1589	Folate-Alcohol and Cancer Pathway	0.999999999999003	-9.96763435678893e-13	5	0	0	1216	4455
WP1438	Influenza A virus infection	0.999999999999131	-8.6852747216426e-13	1	0	0	1216	4455
WP2338	miRNA Biogenesis	0.999999999999131	-8.6852747216426e-13	1	0	0	1216	4455
WP1	Statin Pathway	0.999999999999131	-8.6852747216426e-13	1	0	0	1216	4455
WP1946	Cori Cycle	0.999999999999131	-8.6852747216426e-13	1	0	0	1216	4455
WP1006	metapathway biotransformation	0.999999999999131	-8.6852747216426e-13	1	0	0	1216	4455
WP521	Amino acid conjugation of benzoic acid	1.0000000000014	1.39895213469021e-12	4	0	0	1216	4455
WP1995	Effects of nitric oxide	1.0000000000014	1.39895213469021e-12	4	0	0	1216	4455
WP1603	Nicotine Activity on Chromaffin Cells	1.0000000000014	1.39895213469021e-12	4	0	0	1216	4455
WP1604	Codeine and morphine metabolism	1.00000000001134	1.13398246515291e-11	8	0	0	1216	4455
WP699	Aflatoxin B1 metabolism	1.00000000001134	1.13398246515291e-11	8	0	0	1216	4455
WP237	Glucocorticoid & Mineralcorticoid Metabolism	1.00000000001134	1.13398246515291e-11	8	0	0	1216	4455
WP1600	Nicotine metabolism	1.00000000001319	1.31872685514567e-11	6	0	0	1216	4455
WP80	Nucleotide GPCRs	1.00000000001548	1.54839123354244e-11	11	0	0	1216	4455
WP1001	Peptide GPCRs	1.00000000001548	1.54839123354244e-11	11	0	0	1216	4455
WP117	GPCRs, Other	1.00000000001931	1.93141200982765e-11	91	2	0.00164473684210526	1216	4455	30817,154	ADGRE2,ADRB2
WP195	IL-1 Signaling Pathway	1.00000000002175	2.17548115468786e-11	12	0	0	1216	4455
WP206	Fatty Acid Omega Oxidation	1.00000000002545	2.54519453890864e-11	15	0	0	1216	4455
WP322	Osteoblast Signaling	1.00000000002685	2.68472347511894e-11	13	0	0	1216	4455
WP272	Blood Clotting Cascade	1.00000000003668	3.66783933268139e-11	24	0	0	1216	4455