TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
WP179	Cell cycle	1.9597252368476e-10	-22.3530466518067	102	70	0.0414691943127962	1688	4455	2033,1875,9232,1026,10013,7531,891,254394,898,7465,890,4193,5111,8555,8379,1027,1021,991,1871,10971,990,9088,995,10014,983,7532,4088,8318,9759,1874,4085,8243,84515,2932,3065,4254,1870,4089,4172,3066,4175,55388,10926,1111,375,10459,25,51564,8317,896,699,23595,1876,993,4999,5591,8841,6502,4221,5000,1647,5001,7027,7534,7533,8556,9133,9700,1029,23594	EP300,E2F5,PTTG1,CDKN1A,HDAC6,YWHAE,CCNB1,MCM9,CCNE1,WEE1,CCNA2,MDM2,PCNA,CDC14B,MAD1L1,CDKN1B,CDK6,CDC20,E2F3,YWHAQ,CDC6,PKMYT1,CDC25C,HDAC5,CDK1,YWHAG,SMAD3,CDC45,HDAC4,E2F4,MAD2L1,SMC1A,MCM8,GSK3B,HDAC1,KITLG,E2F2,SMAD4,MCM3,HDAC2,MCM6,MCM10,DBF4,CHEK1,ARF1,MAD2L2,ABL1,HDAC7,CDC7,CCND3,BUB1,ORC3,E2F6,CDC25A,ORC2,PRKDC,HDAC3,SKP2,MEN1,ORC4,GADD45A,ORC5,TFDP1,YWHAZ,YWHAH,CDC14A,CCNB2,ESPL1,CDKN2A,ORC6
WP231	TNF-alpha/NF-kB Signaling Pathway	5.62939555133441e-10	-21.2978488556601	194	115	0.0681279620853081	1688	4455	836,23291,5607,9462,5037,2177,6156,6597,8454,1147,10013,7531,5566,329,1387,10849,9775,3551,10270,5701,835,200081,5134,602,841,4791,2969,5970,6605,9994,6207,4215,207,330,5441,10318,3326,4528,208,10971,57805,857,64343,7763,7532,10401,1654,3839,6599,7185,5719,23118,5709,10293,5590,3065,2932,6198,64332,3838,9861,10454,79155,9618,5700,2549,3066,7323,5693,257397,1611,5966,7186,10238,5977,5713,8518,9252,7341,8533,6205,10010,5781,3320,84172,2091,9020,28511,64425,4214,29110,7128,5702,6132,5747,10399,6601,8439,150684,840,92610,997,9908,2734,4163,7322,10128,7534,6124,10848,4793,9533,7533,11124,26133	CASP3,FBXW11,MAP2K5,RASAL2,PEBP1,FANCD2,RPL30,SMARCA4,CUL1,CHUK,HDAC6,YWHAE,PRKACA,BIRC2,CREBBP,CD3EAP,EIF4A3,IKBKB,AKAP8,PSMC2,CASP2,TXLNA,PDCD2,BCL3,CASP8,NFKB2,GTF2I,RELA,SMARCE1,CASP8AP2,RPS13,MAP3K3,AKT1,BIRC3,POLR2L,TNIP1,HSP90AB1,MTIF2,AKT2,YWHAQ,CCAR2,CAV1,AZI2,ZFAND5,YWHAG,PIAS3,DDX3X,KPNA3,SMARCC1,TRAF1,PSMD13,TAB2,PSMD3,TRAIP,PRKCZ,HDAC1,GSK3B,RPS6KB1,NFKBIZ,KPNA2,PSMD6,TAB1,TNIP2,TRAF4,PSMC1,GAB1,HDAC2,UBE2D3,PSMB5,TAB3,DAP,REL,TRAF2,DCAF7,DPF2,PSMD7,IKBKAP,RPS6KA5,SUMO1,COPS3,RPS11,TANK,PTPN11,HSP90AA1,POLR1B,FBL,MAP3K14,NKIRAS2,POLR1E,MAP3K1,TBK1,TNFAIP3,PSMC3,RPL8,PTK2,GNB2L1,SMARCC2,NSMAF,COMMD1,CASP7,TIFA,CDC34,G3BP2,GLG1,MCC,UBE2D2,LRPPRC,YWHAZ,RPL4,PPP1R13L,NFKBIB,POLR1C,YWHAH,FAF1,TRPC4AP
WP2446	RB in Cancer	2.97963985577308e-09	-19.6314633974999	87	60	0.0355450236966825	1688	4455	3146,4175,3015,5894,6240,1111,1026,6596,25942,4863,891,580,898,7153,25,7465,4193,5111,890,9126,8317,896,7272,10733,1027,1021,2956,8819,6595,993,5984,5983,5931,5591,5422,6502,1871,6241,10592,2189,10714,983,79027,5557,8318,5426,5427,1633,7027,8243,1719,3065,7298,3148,7029,9133,1870,6839,11124,4172	HMGB1,MCM6,H2AFZ,RAF1,RRM1,CHEK1,CDKN1A,HLTF,SIN3A,NPAT,CCNB1,BARD1,CCNE1,TOP2A,ABL1,WEE1,MDM2,PCNA,CCNA2,SMC3,CDC7,CCND3,TTK,PLK4,CDKN1B,CDK6,MSH6,SAP30,SMARCA2,CDC25A,RFC4,RFC3,RBBP7,PRKDC,POLA1,SKP2,E2F3,RRM2,SMC2,FANCG,POLD3,CDK1,ZNF655,PRIM1,CDC45,POLE,POLE2,DCK,TFDP1,SMC1A,DHFR,HDAC1,TYMS,HMGB2,TFDP2,CCNB2,E2F2,SUV39H1,FAF1,MCM3
WP437	EGFR1 Signaling Pathway	7.72414014478315e-09	-18.6789153284765	177	104	0.0616113744075829	1688	4455	5599,5753,5607,5894,10928,5037,5879,5604,9712,6777,1050,25942,51079,85021,30011,5606,3727,1399,6196,6464,8651,5899,8882,5296,8503,4215,6655,10188,207,10318,4690,5777,83737,842,5868,857,6773,378,6622,9021,4088,5335,4087,1398,8976,5590,3065,2185,8462,1500,5594,2549,6004,3636,3856,7410,29924,5900,9252,1915,1999,5586,466,65125,50807,5781,5584,3717,8520,9020,54206,5598,6774,10253,1843,4214,6667,7050,5609,5931,6654,9219,5295,58513,8625,5782,3092,5339,9564,26060,5605,5921,5595,2885,3064,160,2886,55198,6776,5337,6633,3875,3265,6197	MAPK8,PTK6,MAP2K5,RAF1,RALBP1,PEBP1,RAC1,MAP2K1,USP6NL,STAT5B,CEBPA,SIN3A,NDUFA13,REPS1,SH3KBP1,MAP2K3,JUND,CRKL,RPS6KA2,SHC1,SOCS1,RALB,ZPR1,PIK3R2,PIK3R3,MAP3K3,SOS2,TNK2,AKT1,TNIP1,NCK1,PTPN6,ITCH,CASP9,RAB5A,CAV1,STAT2,ARF4,SNCA,SOCS3,SMAD3,PLCG1,SMAD2,CRK,WASL,PRKCZ,HDAC1,PTK2B,KLF11,CTNND1,MAPK1,GAB1,RGS16,INPPL1,KRT8,VAV2,EPN1,RALGDS,RPS6KA5,EEF1A1,ELF3,PKN2,ATF1,WNK1,ASAP1,PTPN11,PRKCI,JAK2,HAT1,MAP3K14,ERRFI1,MAPK7,STAT3,SPRY2,DUSP1,MAP3K1,SP1,TGIF1,MAP2K7,RBBP7,SOS1,MTA2,PIK3R1,EPS15L1,RFXANK,PTPN12,HIP1,PLEC,BCAR1,APPL1,MAP2K2,RASA1,MAPK3,GRB2,HTT,AP2A1,GRB7,APPL2,STAT5A,PLD1,SNRPD2,KRT18,HRAS,RPS6KA3
WP111	Electron Transport Chain	1.35098983168696e-07	-15.8172581185171	93	60	0.0355450236966825	1688	4455	4698,1329,4729,4719,4712,6391,7381,29796,4711,9481,521,4706,1327,4697,506,374291,4709,4724,4723,4695,4710,1337,10476,7385,4714,4715,4731,1349,10975,4700,4696,55967,4705,4720,4704,516,93974,1350,4717,9016,27089,1353,7384,514,9551,6392,515,10063,291,518,27109,509,9167,1351,4694,7388,498,6341,4713,4702	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,SDHC,UQCRB,UQCR10,NDUFB5,SLC25A27,ATP5I,NDUFAB1,COX4I1,NDUFA4,ATP5B,NDUFS7,NDUFB3,NDUFS4,NDUFV1,NDUFA2,NDUFB4,COX6A1,ATP5H,UQCRC2,NDUFB8,NDUFB9,NDUFV3,COX7B,UQCR11,NDUFA6,NDUFA3,NDUFA12,NDUFA10,NDUFS2,NDUFA9,ATP5G1,ATPIF1,COX7C,NDUFC1,SLC25A14,UQCRQ,COX11,UQCRC1,ATP5E,ATP5J2,SDHD,ATP5F1,COX17,SLC25A4,ATP5G3,ATP5S,ATP5C1,COX7A2L,COX8A,NDUFA1,UQCRH,ATP5A1,SCO1,NDUFB7,NDUFA8
WP411	mRNA processing	1.70750046751242e-07	-15.5830650646962	134	80	0.0473933649289099	1688	4455	9410,3182,10978,6636,6635,53981,6638,83443,10992,3181,29894,6427,84844,6429,3191,3192,5094,6421,10291,6629,58155,5681,8731,5725,6433,3183,10921,51690,140890,10907,10421,1665,11051,1198,8449,10236,7307,5496,8243,9128,2521,6637,8899,6627,10594,51362,1195,10250,3276,1660,23283,10482,3187,22826,9343,3184,57396,6729,22803,4904,24148,4670,1196,1479,6430,6829,8175,5430,6626,23450,10181,11129,23405,1478,3190,57819,22916,6428,6633,9584	SNRNP40,HNRNPAB,CLP1,SNRPF,SNRPE,CPSF2,SNRPN,SF3B5,SF3B2,HNRNPA2B1,CPSF1,SRSF2,PHF5A,SRSF4,HNRNPL,HNRNPU,PCBP2,SFPQ,SF3A1,SNRPB2,PTBP2,PSKH1,RNMT,PTBP1,SFSWAP,HNRNPC,RNPS1,LSM7,SREK1,TXNL4A,CD2BP2,DHX15,NUDT21,CLK3,DHX16,HNRNPR,U2AF1,PPM1G,SMC1A,PRPF4,FUS,SNRPG,PRPF4B,SNRPA1,PRPF8,CDC40,CLK1,SRRM1,PRMT1,DHX9,CSTF2T,NXF1,HNRNPH1,DNAJC8,EFTUD2,HNRNPD,CLK4,SRP54,XRN2,YBX1,PRPF6,HNRNPM,CLK2,CSTF3,SRSF5,SUPT5H,SF3A2,POLR2A,SNRPA,SF3B3,RBM5,CLASRP,DICER1,CSTF2,HNRNPK,LSM2,NCBP2,SRSF3,SNRPD2,RBM39
WP138	Androgen receptor signaling pathway	6.9796981588172e-07	-14.1750899788415	88	56	0.033175355450237	1688	4455	51588,2033,5883,5879,2119,10524,64800,1026,11315,898,23028,7341,811,1387,8611,4193,7337,1499,5296,6047,5901,6774,5970,6605,9475,3985,10498,6667,23411,387,207,11034,5295,29893,2274,5747,10399,857,672,388,4088,10401,10273,6049,8202,8031,1616,24149,3065,2932,6093,9611,9604,4089,573,7041	PIAS4,EP300,RAD9A,RAC1,ETV5,KAT5,EFCAB6,CDKN1A,PARK7,CCNE1,KDM1A,SUMO1,CALR,CREBBP,PLPP1,MDM2,UBE3A,CTNNB1,PIK3R2,RNF4,RAN,STAT3,RELA,SMARCE1,ROCK2,LIMK2,CARM1,SP1,SIRT1,RHOA,AKT1,DSTN,PIK3R1,PSMC3IP,FHL2,PTK2,GNB2L1,CAV1,BRCA1,RHOB,SMAD3,PIAS3,STUB1,RNF6,NCOA3,NCOA4,DAXX,ZNF318,HDAC1,GSK3B,ROCK1,NCOR1,RNF14,SMAD4,BAG1,TGFB1I1
WP477	Cytoplasmic Ribosomal Proteins	3.50635351774115e-06	-12.5609339443348	118	69	0.0408767772511848	1688	4455	6181,6235,6156,6193,9801,6135,6218,6147,6217,6196,6134,6194,6168,6227,6222,6207,11224,7311,6133,6230,6169,6142,6232,4736,6203,3921,6165,6233,6208,6176,9045,6173,6198,6146,6188,6231,6224,6202,6122,6209,6187,6138,6125,6164,6137,9349,6234,6139,6205,6155,6143,6228,6199,6154,6204,6171,6132,6129,6175,25873,6189,6130,6136,6210,6158,6124,6152,6206,6197	RPLP2,RPS29,RPL30,RPS5,MRPL19,RPL11,RPS17,RPL23A,RPS16,RPS6KA2,RPL10,RPS6,RPL37A,RPS21,RPS18,RPS13,RPL35,UBA52,RPL9,RPS25,RPL38,RPL18A,RPS27,RPL10A,RPS9,RPSA,RPL35A,RPS27A,RPS14,RPLP1,RPL14,RPL36A,RPS6KB1,RPL22,RPS3,RPS26,RPS20,RPS8,RPL3,RPS15,RPS2,RPL15,RPL5,RPL34,RPL13,RPL23,RPS28,RPL17,RPS11,RPL27,RPL19,RPS23,RPS6KB2,RPL26,RPS10,RPL41,RPL8,RPL7,RPLP0,RPL36,RPS3A,RPL7A,RPL12,RPS15A,RPL28,RPL4,RPL24,RPS12,RPS6KA3
WP2034	Leptin signaling pathway	5.1657893297299e-06	-12.1734526442751	60	40	0.023696682464455	1688	4455	5599,2475,5966,5894,5879,8835,5604,2064,1147,6777,598,1154,6464,3551,5296,581,5781,6194,3717,6774,5970,31,6667,387,207,6654,5295,5605,1073,5595,30837,9021,2885,5335,3840,2534,25970,6198,5594,3265	MAPK8,MTOR,REL,RAF1,RAC1,SOCS2,MAP2K1,ERBB2,CHUK,STAT5B,BCL2L1,CISH,SHC1,IKBKB,PIK3R2,BAX,PTPN11,RPS6,JAK2,STAT3,RELA,ACACA,SP1,RHOA,AKT1,SOS1,PIK3R1,MAP2K2,CFL2,MAPK3,SOCS7,SOCS3,GRB2,PLCG1,KPNA4,FYN,SH2B1,RPS6KB1,MAPK1,HRAS
WP364	IL-6 Signaling Pathway	1.95138874296196e-05	-10.8443841699935	99	58	0.0343601895734597	1688	4455	2033,5599,836,3636,5894,5879,5604,2064,5520,51701,4067,2309,5519,1387,6196,6464,3572,5296,5781,6446,3717,2065,3320,5521,6774,1977,2242,4303,207,6654,5295,842,5747,958,5605,7297,5595,9021,2885,5529,5335,2534,1616,3569,5608,1978,5524,2185,2932,3065,5527,6198,5594,3265,5528,2549,6416,4137	EP300,MAPK8,CASP3,INPPL1,RAF1,RAC1,MAP2K1,ERBB2,PPP2R2A,NLK,LYN,FOXO3,PPP2R1B,CREBBP,RPS6KA2,SHC1,IL6ST,PIK3R2,PTPN11,SGK1,JAK2,ERBB3,HSP90AA1,PPP2R2B,STAT3,EIF4E,FES,FOXO4,AKT1,SOS1,PIK3R1,CASP9,PTK2,CD40,MAP2K2,TYK2,MAPK3,SOCS3,GRB2,PPP2R5E,PLCG1,FYN,DAXX,IL6,MAP2K6,EIF4EBP1,PPP2R4,PTK2B,GSK3B,HDAC1,PPP2R5C,RPS6KB1,MAPK1,HRAS,PPP2R5D,GAB1,MAP2K4,MAPT
WP2037	Prolactin Signaling Pathway	2.84386267346391e-05	-10.4677622406002	75	46	0.0272511848341232	1688	4455	5599,836,5479,2475,5894,5879,8835,7410,5604,2064,6777,5478,1154,6196,8651,6464,5296,5601,5781,6194,3717,6774,5970,207,6654,5295,5747,5605,7532,5595,9021,2885,10401,8660,2534,1978,3688,2932,6198,6776,7534,4793,5594,4752,3265,3659	MAPK8,CASP3,PPIB,MTOR,RAF1,RAC1,SOCS2,VAV2,MAP2K1,ERBB2,STAT5B,PPIA,CISH,RPS6KA2,SOCS1,SHC1,PIK3R2,MAPK9,PTPN11,RPS6,JAK2,STAT3,RELA,AKT1,SOS1,PIK3R1,PTK2,MAP2K2,YWHAG,MAPK3,SOCS3,GRB2,PIAS3,IRS2,FYN,EIF4EBP1,ITGB1,GSK3B,RPS6KB1,STAT5A,YWHAZ,NFKBIB,MAPK1,NEK3,HRAS,IRF1
WP183	Proteasome Degradation	3.00473688808281e-05	-10.4127354588588	65	41	0.0242890995260664	1688	4455	7323,5689,5693,3015,7317,5683,5713,5716,5720,5715,3105,5708,5687,5696,5688,5701,5717,7314,7321,5686,5694,5692,5702,5695,5710,7347,5685,7316,5691,5704,3012,5719,5706,5709,7322,3014,5690,5705,9861,5700,5711	UBE2D3,PSMB1,PSMB5,H2AFZ,UBA1,PSMA2,PSMD7,PSMD10,PSME1,PSMD9,HLA-A,PSMD2,PSMA6,PSMB8,PSMA7,PSMC2,PSMD11,UBB,UBE2D1,PSMA5,PSMB6,PSMB4,PSMC3,PSMB7,PSMD4,UCHL3,PSMA4,UBC,PSMB3,PSMC4,HIST1H2AE,PSMD13,PSMC6,PSMD3,UBE2D2,H2AFX,PSMB2,PSMC5,PSMD6,PSMC1,PSMD5
WP481	Insulin Signaling	3.0841275727478e-05	-10.3866566441235	163	87	0.0515402843601896	1688	4455	5599,5607,6517,10580,100533105,7249,2475,5894,5879,5604,6813,5606,6196,6464,8651,10487,3551,5296,8503,8986,1977,4294,4215,6655,207,2931,208,9064,6009,9021,8660,1398,1978,5590,4296,6722,2932,6198,382,5594,2549,3636,1958,9175,5562,30849,375,9252,2309,4641,3799,11183,5211,5601,5781,5584,4293,6446,9020,5598,4214,6199,5170,5871,23433,5609,6654,5295,9265,6616,6810,5605,5595,2885,5792,57761,3643,5608,8773,5597,7494,11127,4217,9882,3265,6416,6197	MAPK8,MAP2K5,SLC2A4,SORBS1,C8orf44-SGK3,TSC2,MTOR,RAF1,RAC1,MAP2K1,STXBP2,MAP2K3,RPS6KA2,SHC1,SOCS1,CAP1,IKBKB,PIK3R2,PIK3R3,RPS6KA4,EIF4E,MAP3K10,MAP3K3,SOS2,AKT1,GSK3A,AKT2,MAP3K6,RHEB,SOCS3,IRS2,CRK,EIF4EBP1,PRKCZ,MAP3K11,SRF,GSK3B,RPS6KB1,ARF6,MAPK1,GAB1,INPPL1,EGR1,MAP3K13,PRKAA1,PIK3R4,ARF1,RPS6KA5,FOXO3,MYO1C,KIF5B,MAP4K5,PFKL,MAPK9,PTPN11,PRKCI,MAP3K9,SGK1,MAP3K14,MAPK7,MAP3K1,RPS6KB2,PDPK1,MAP4K2,RHOQ,MAP2K7,SOS1,PIK3R1,CYTH3,SNAP25,STX4,MAP2K2,MAPK3,GRB2,PTPRF,TRIB3,INSR,MAP2K6,SNAP23,MAPK6,XBP1,KIF3A,MAP3K5,TBC1D4,HRAS,MAP2K4,RPS6KA3
WP623	Oxidative phosphorylation	5.01961967890336e-05	-9.89957129531124	54	35	0.0207345971563981	1688	4455	4698,4729,4719,4712,4711,537,521,4706,4697,506,374291,4724,4723,4695,4710,10476,4714,4715,4731,4700,4696,4705,4720,10159,516,4704,4717,514,9551,515,518,27109,498,4702,4713	NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFB5,ATP6AP1,ATP5I,NDUFAB1,NDUFA4,ATP5B,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,ATP5H,NDUFB8,NDUFB9,NDUFV3,NDUFA6,NDUFA3,NDUFA10,NDUFS2,ATP6AP2,ATP5G1,NDUFA9,NDUFC1,ATP5E,ATP5J2,ATP5F1,ATP5G3,ATP5S,ATP5A1,NDUFA8,NDUFB7
WP1982	SREBP signalling	5.11023391466854e-05	-9.88168028593761	64	40	0.023696682464455	1688	4455	6396,2475,9871,6319,7376,5566,10483,3422,3157,6721,56681,9632,3837,31,6667,2222,3156,51360,23411,10802,10484,1024,207,2931,5468,2194,22872,51128,10427,4047,3638,22937,51586,1622,2224,4190,57678,7528,11236,8720	SEC13,MTOR,SEC24D,SCD,NR1H2,PRKACA,SEC23B,IDI1,HMGCS1,SREBF2,SAR1A,SEC24C,KPNB1,ACACA,SP1,FDFT1,HMGCR,MBTPS2,SIRT1,SEC24A,SEC23A,CDK8,AKT1,GSK3A,PPARG,FASN,SEC31A,SAR1B,SEC24B,LSS,INSIG1,SCAP,MED15,DBI,FDPS,MDH1,GPAM,YY1,RNF139,MBTPS1
WP2332	Interleukin-11 Signaling Pathway	0.000132178743661269	-8.93135543272377	40	27	0.0159952606635071	1688	4455	5170,3590,207,632,5894,5295,1147,7525,7297,5595,9021,2885,10401,466,2534,3572,3673,5524,5296,3551,6194,5781,3717,6774,5594,5970,3265	PDPK1,IL11RA,AKT1,BGLAP,RAF1,PIK3R1,CHUK,YES1,TYK2,MAPK3,SOCS3,GRB2,PIAS3,ATF1,FYN,IL6ST,ITGA2,PPP2R4,PIK3R2,IKBKB,RPS6,PTPN11,JAK2,STAT3,MAPK1,RELA,HRAS
WP466	DNA Replication	0.000138325225916193	-8.88590293595394	42	28	0.0165876777251185	1688	4455	5984,55388,5983,4999,4175,7311,5558,5422,10926,990,10714,5424,5982,7316,5557,8318,51053,5111,5426,5427,5000,8317,5001,5981,23595,4172,23594,5425	RFC4,MCM10,RFC3,ORC2,MCM6,UBA52,PRIM2,POLA1,DBF4,CDC6,POLD3,POLD1,RFC2,UBC,PRIM1,CDC45,GMNN,PCNA,POLE,POLE2,ORC4,CDC7,ORC5,RFC1,ORC3,MCM3,ORC6,POLD2
WP366	TGF-beta Receptor Signaling Pathway	0.000172175080465465	-8.66699868918665	151	79	0.0468009478672986	1688	4455	2033,5599,1875,5520,8454,1026,898,9372,5606,58533,3727,1387,64682,8723,1499,51343,5296,2354,10393,163,51434,9972,7321,1386,11171,1021,9978,10413,467,163126,55914,857,8697,8021,983,4088,817,7514,4087,1616,1874,3065,6093,7029,10454,57154,409,4089,7323,51433,10664,4205,2113,2309,7341,114790,22938,3726,4091,4801,3837,6667,7050,993,79753,4303,6643,5295,29882,64750,2339,996,10131,5608,7027,4802,7322,9063,9133	EP300,MAPK8,E2F5,PPP2R2A,CUL1,CDKN1A,CCNE1,ZFYVE9,MAP2K3,SNX6,JUND,CREBBP,ANAPC1,SNX4,CTNNB1,FZR1,PIK3R2,FOSB,ANAPC10,AP2B1,ANAPC7,NUP153,UBE2D1,ATF2,STRAP,CDK6,RBX1,YAP1,ATF3,EID2,ERBB2IP,CAV1,CDC23,NUP214,CDK1,SMAD3,CAMK2D,XPO1,SMAD2,DAXX,E2F4,HDAC1,ROCK1,TFDP2,TAB1,SMURF1,ARRB2,SMAD4,UBE2D3,ANAPC5,CTCF,MEF2A,ETS1,FOXO3,SUMO1,STK11IP,SNW1,JUNB,SMAD6,NFYB,KPNB1,SP1,TGIF1,CDC25A,SNIP1,FOXO4,SNX2,PIK3R1,ANAPC2,SMURF2,FNTA,CDC27,TRAP1,MAP2K6,TFDP1,NFYC,UBE2D2,PIAS2,CCNB2
WP2359	Parkin-Ubiquitin Proteasomal System pathway	0.000195204776550826	-8.5414614142497	73	43	0.0254739336492891	1688	4455	5071,7280,7317,10383,5713,5716,8454,2812,5715,3303,898,51182,5708,9246,6477,5701,51465,10213,5717,25897,841,7327,10381,8573,7332,5702,118424,5710,3304,6622,5704,10273,3305,3308,5719,5706,5709,6478,9861,5705,5700,203068,5711	PARK2,TUBB2A,UBA1,TUBB4B,PSMD7,PSMD10,CUL1,GP1BB,PSMD9,HSPA1A,CCNE1,HSPA14,PSMD2,UBE2L6,SIAH1,PSMC2,UBE2J1,PSMD14,PSMD11,RNF19A,CASP8,UBE2G2,TUBB3,CASK,UBE2L3,PSMC3,UBE2J2,PSMD4,HSPA1B,SNCA,PSMC4,STUB1,HSPA1L,HSPA4,PSMD13,PSMC6,PSMD3,SIAH2,PSMD6,PSMC5,PSMC1,TUBB,PSMD5
WP585	Interferon type I	0.000260548826020777	-8.25272028239246	49	31	0.0183649289099526	1688	4455	2475,5777,5295,5879,3276,79109,10399,3454,9252,7297,5606,6773,9021,57521,10401,1399,8660,5906,2534,8651,1398,5608,1978,5296,5781,8986,6776,6774,1977,64223,4214	MTOR,PTPN6,PIK3R1,RAC1,PRMT1,MAPKAP1,GNB2L1,IFNAR1,RPS6KA5,TYK2,MAP2K3,STAT2,SOCS3,RPTOR,PIAS3,CRKL,IRS2,RAP1A,FYN,SOCS1,CRK,MAP2K6,EIF4EBP1,PIK3R2,PTPN11,RPS6KA4,STAT5A,STAT3,EIF4E,MLST8,MAP3K1
WP45	G1 to S cell cycle control	0.000337688011822772	-7.99338813069126	68	40	0.023696682464455	1688	4455	1030,4175,1028,1388,1875,10488,1026,891,898,1031,7465,4193,5111,896,1027,23595,1032,1021,901,1876,993,4999,5558,1871,983,5557,4331,8318,1647,5426,5427,5000,1874,5001,7027,7029,1870,23594,1029,4172	CDKN2B,MCM6,CDKN1C,ATF6B,E2F5,CREB3,CDKN1A,CCNB1,CCNE1,CDKN2C,WEE1,MDM2,PCNA,CCND3,CDKN1B,ORC3,CDKN2D,CDK6,CCNG2,E2F6,CDC25A,ORC2,PRIM2,E2F3,CDK1,PRIM1,MNAT1,CDC45,GADD45A,POLE,POLE2,ORC4,E2F4,ORC5,TFDP1,TFDP2,E2F2,ORC6,CDKN2A,MCM3
WP395	IL-4 signaling Pathway	0.00058484140258515	-7.44416985418053	63	37	0.0219194312796209	1688	4455	2033,5074,3597,598,2113,1387,8651,6464,5296,5781,5584,653604,3717,5970,1386,2242,9655,207,6654,5777,5295,5747,7297,5921,5595,9021,2885,8660,5335,7852,2534,6778,5590,6776,6198,3159,5594	EP300,PAWR,IL13RA1,BCL2L1,ETS1,CREBBP,SOCS1,SHC1,PIK3R2,PTPN11,PRKCI,HIST2H3D,JAK2,RELA,ATF2,FES,SOCS5,AKT1,SOS1,PTPN6,PIK3R1,PTK2,TYK2,RASA1,MAPK3,SOCS3,GRB2,IRS2,PLCG1,CXCR4,FYN,STAT6,PRKCZ,STAT5A,RPS6KB1,HMGA1,MAPK1
WP61	Delta-Notch Signaling Pathway	0.000749042865644488	-7.19671434558467	85	47	0.0278436018957346	1688	4455	2033,54567,3955,102,6929,9541,8454,161882,25942,83464,23509,6015,23493,22938,9253,182,5296,5664,3717,9794,6774,5970,8819,55534,3280,6868,207,51107,9978,83737,5295,5045,6502,5595,4088,23013,2932,3065,3516,9611,4086,7528,5594,4089,23385,3066,8650	EP300,DLL4,LFNG,ADAM10,TCF3,CIR1,CUL1,ZFPM1,SIN3A,APH1B,POFUT1,RING1,HEY2,SNW1,NUMBL,JAG1,PIK3R2,PSEN2,JAK2,MAML1,STAT3,RELA,SAP30,MAML3,HES1,ADAM17,AKT1,APH1A,RBX1,ITCH,PIK3R1,FURIN,SKP2,MAPK3,SMAD3,SPEN,GSK3B,HDAC1,RBPJ,NCOR1,SMAD1,YY1,MAPK1,SMAD4,NCSTN,HDAC2,NUMB
WP404	Nucleotide Metabolism	0.000812880975897478	-7.11492586024426	20	15	0.00888625592417062	1688	4455	6723,3251,10797,50484,5422,5428,6303,6240,4831,1719,3614,158,6241,5424,4946	SRM,HPRT1,MTHFD2,RRM2B,POLA1,POLG,SAT1,RRM1,NME2,DHFR,IMPDH1,ADSL,RRM2,POLD1,OAZ1
WP581	EPO Receptor Signaling	0.00115003348917183	-6.767964216012	26	18	0.0106635071090047	1688	4455	207,5163,6654,5894,5604,6777,5605,5921,5595,8660,2885,1154,8651,6464,6776,3717,5594,6774	AKT1,PDK1,SOS1,RAF1,MAP2K1,STAT5B,MAP2K2,RASA1,MAPK3,IRS2,GRB2,CISH,SOCS1,SHC1,STAT5A,JAK2,MAPK1,STAT3
WP1541	Energy Metabolism	0.00121737532452448	-6.7110581111057	48	29	0.0171800947867299	1688	4455	23411,2033,51106,5468,2551,5565,6256,5562,5465,3276,814,5571,100271849,4205,5532,4209,2309,5467,4899,10514,51422,5534,2932,3065,5533,10891,2101,1386,5469	SIRT1,EP300,TFB1M,PPARG,GABPA,PRKAB2,RXRA,PRKAA1,PPARA,PRMT1,CAMK4,PRKAG1,MEF2B,MEF2A,PPP3CB,MEF2D,FOXO3,PPARD,NRF1,MYBBP1A,PRKAG2,PPP3R1,GSK3B,HDAC1,PPP3CC,PPARGC1A,ESRRA,ATF2,MED1
WP707	DNA damage response	0.00124978232460848	-6.68478588314533	67	38	0.0225118483412322	1688	4455	836,5883,55367,10912,2177,1111,1026,891,898,25,4193,5366,896,581,1027,84126,4361,841,1021,1643,993,5810,9874,842,672,27244,995,983,1647,50484,5888,4616,8243,3014,317,5981,9133,2810	CASP3,RAD9A,PIDD1,GADD45G,FANCD2,CHEK1,CDKN1A,CCNB1,CCNE1,ABL1,MDM2,PMAIP1,CCND3,BAX,CDKN1B,ATRIP,MRE11A,CASP8,CDK6,DDB2,CDC25A,RAD1,TLK1,CASP9,BRCA1,SESN1,CDC25C,CDK1,GADD45A,RRM2B,RAD51,GADD45B,SMC1A,H2AFX,APAF1,RFC1,CCNB2,SFN
WP2377	Integrated Pancreatic Cancer Pathway	0.0013904174760443	-6.57815123445539	194	94	0.0556872037914692	1688	4455	2033,5599,836,92335,3732,5894,6256,5879,9232,5604,2064,324,1147,1026,898,3727,1387,4193,5111,5906,890,5610,1499,1027,4361,7159,841,175,3486,23411,5914,207,2931,5163,4690,3326,842,672,7422,995,1605,6009,2260,5743,4087,4830,1398,1616,1874,7298,2972,5594,4089,823,4137,1030,1676,1958,6908,7186,6240,3978,1111,375,641,7057,2146,7153,25,3726,5601,581,5598,4091,6667,7150,5915,2512,9821,6654,5422,2100,5595,2885,4331,5308,840,1647,5888,2281,6776,10848,317,4217	EP300,MAPK8,CASP3,STRADA,CD82,RAF1,RXRA,RAC1,PTTG1,MAP2K1,ERBB2,APC,CHUK,CDKN1A,CCNE1,JUND,CREBBP,MDM2,PCNA,RAP1A,CCNA2,EIF2AK2,CTNNB1,CDKN1B,MRE11A,TP53BP2,CASP8,AGA,IGFBP3,SIRT1,RARA,AKT1,GSK3A,PDK1,NCK1,HSP90AB1,CASP9,BRCA1,VEGFA,CDC25C,DAG1,RHEB,FGFR1,PTGS2,SMAD2,NME1,CRK,DAXX,E2F4,TYMS,BRF1,MAPK1,SMAD4,CAPN1,MAPT,CDKN2B,DFFA,EGR1,TBP,TRAF2,RRM1,LIG1,CHEK1,ARF1,BLM,THBS1,EZH2,TOP2A,ABL1,JUNB,MAPK9,BAX,MAPK7,SMAD6,SP1,TOP1,RARB,FTL,RB1CC1,SOS1,POLA1,ESR2,MAPK3,GRB2,MNAT1,PITX2,CASP7,GADD45A,RAD51,FKBP1B,STAT5A,PPP1R13L,APAF1,MAP3K5
WP2380	BDNF signaling pathway	0.0017469135110485	-6.3499047561831	144	72	0.042654028436019	1688	4455	391,5599,836,5607,7249,2475,5894,5879,5604,324,6777,84894,5906,1499,6464,6792,1808,5296,1739,6194,4082,1977,5970,10818,207,4690,8660,5335,2534,1978,25970,2185,2932,6198,5594,23373,4137,6272,1958,8536,7410,5562,814,4205,9252,2309,8878,1938,5601,5781,3717,4904,5598,10018,6774,4214,5170,23191,6868,5295,10399,5605,10048,5595,2885,5792,57498,1965,6776,4776,3265,6197	RHOG,MAPK8,CASP3,MAP2K5,TSC2,MTOR,RAF1,RAC1,MAP2K1,APC,STAT5B,LINGO1,RAP1A,CTNNB1,SHC1,CDKL5,DPYSL2,PIK3R2,DLG1,RPS6,MARCKS,EIF4E,RELA,FRS2,AKT1,NCK1,IRS2,PLCG1,FYN,EIF4EBP1,SH2B1,PTK2B,GSK3B,RPS6KB1,MAPK1,CRTC1,MAPT,SORT1,EGR1,CAMK1,VAV2,PRKAA1,CAMK4,MEF2A,RPS6KA5,FOXO3,SQSTM1,EEF2,MAPK9,PTPN11,JAK2,YBX1,MAPK7,BCL2L11,STAT3,MAP3K1,PDPK1,CYFIP1,ADAM17,PIK3R1,GNB2L1,MAP2K2,RANBP9,MAPK3,GRB2,PTPRF,KIDINS220,EIF2S1,STAT5A,NFATC4,HRAS,RPS6KA3
WP2032	TSH signaling pathway	0.0020320420371	-6.19871406193067	64	36	0.0213270142180095	1688	4455	673,2475,5894,5604,5900,2782,7270,898,5606,5906,5296,896,6194,8458,1027,3717,5144,6774,2771,5170,328,207,5295,5908,23513,2773,5595,2770,2778,2768,5608,6198,5337,10672,5594,3265	BRAF,MTOR,RAF1,MAP2K1,RALGDS,GNB1,TTF1,CCNE1,MAP2K3,RAP1A,PIK3R2,CCND3,RPS6,TTF2,CDKN1B,JAK2,PDE4D,STAT3,GNAI2,PDPK1,APEX1,AKT1,PIK3R1,RAP1B,SCRIB,GNAI3,MAPK3,GNAI1,GNAS,GNA12,MAP2K6,RPS6KB1,PLD1,GNA13,MAPK1,HRAS
WP710	DNA damage response (only ATM dependent)	0.00253810811215578	-5.97633631321508	91	48	0.028436018957346	1688	4455	5599,3146,638,5879,6648,2064,324,1026,2309,5881,7474,25,4193,6464,1499,5366,896,5601,581,1027,5106,4791,10018,1856,4214,901,578,6655,387,7480,5163,207,6654,208,6342,7481,1857,2885,4088,847,5529,3643,10023,5527,2932,5594,4089,1029	MAPK8,HMGB1,BIK,RAC1,SOD2,ERBB2,APC,CDKN1A,FOXO3,RAC3,WNT5A,ABL1,MDM2,SHC1,CTNNB1,PMAIP1,CCND3,MAPK9,BAX,CDKN1B,PCK2,NFKB2,BCL2L11,DVL2,MAP3K1,CCNG2,BAK1,SOS2,RHOA,WNT10B,PDK1,AKT1,SOS1,AKT2,SCP2,WNT11,DVL3,GRB2,SMAD3,CAT,PPP2R5E,INSR,FRAT1,PPP2R5C,GSK3B,MAPK1,SMAD4,CDKN2A
WP304	Kit Receptor Signaling Pathway	0.0027470907493466	-5.89721283661321	67	37	0.0219194312796209	1688	4455	2033,161742,200734,5894,7410,5604,6777,4067,30011,25,1399,1154,6464,8651,5296,4286,5781,3717,6774,2242,9655,207,6654,5777,5295,7525,5921,2885,5335,2534,1398,2886,1213,4254,6776,5594,3265	EP300,SPRED1,SPRED2,RAF1,VAV2,MAP2K1,STAT5B,LYN,SH3KBP1,ABL1,CRKL,CISH,SHC1,SOCS1,PIK3R2,MITF,PTPN11,JAK2,STAT3,FES,SOCS5,AKT1,SOS1,PTPN6,PIK3R1,YES1,RASA1,GRB2,PLCG1,FYN,CRK,GRB7,CLTC,KITLG,STAT5A,MAPK1,HRAS
WP49	IL-2 Signaling pathway	0.00348539890912257	-5.65917277672264	42	25	0.0148104265402844	1688	4455	207,6654,5894,5295,5604,6777,2309,5605,5595,9021,2885,1399,1154,2534,6464,5781,6194,2185,6776,6198,6774,5594,3265,4137,6199	AKT1,SOS1,RAF1,PIK3R1,MAP2K1,STAT5B,FOXO3,MAP2K2,MAPK3,SOCS3,GRB2,CRKL,CISH,FYN,SHC1,PTPN11,RPS6,PTK2B,STAT5A,RPS6KB1,STAT3,MAPK1,HRAS,MAPT,RPS6KB2
WP107	Translation Factors	0.00369575273533617	-5.60057102805315	57	32	0.018957345971564	1688	4455	1964,9451,8672,3646,1915,3692,5610,1938,23277,10209,8665,1983,1977,26986,1936,1984,8669,1974,7458,9669,8666,8661,8667,1981,1968,1978,1967,8892,1965,1979,8662,8637	EIF1AX,EIF2AK3,EIF4G3,EIF3E,EEF1A1,EIF6,EIF2AK2,EEF2,CLUH,EIF1,EIF3F,EIF5,EIF4E,PABPC1,EEF1D,EIF5A,EIF3J,EIF4A2,EIF4H,EIF5B,EIF3G,EIF3A,EIF3H,EIF4G1,EIF2S3,EIF4EBP1,EIF2B1,EIF2B2,EIF2S1,EIF4EBP2,EIF3B,EIF4EBP3
WP22	IL-9 Signaling Pathway	0.00394148275429673	-5.53619829289016	24	16	0.00947867298578199	1688	4455	207,5295,5604,10524,6777,5605,7297,5595,9021,8660,2885,6464,5781,6776,5594,6774	AKT1,PIK3R1,MAP2K1,KAT5,STAT5B,MAP2K2,TYK2,MAPK3,SOCS3,IRS2,GRB2,SHC1,PTPN11,STAT5A,MAPK1,STAT3
WP286	IL-3 Signaling Pathway	0.00410086745864456	-5.49655675237161	104	53	0.0313981042654028	1688	4455	5599,3397,5894,5879,8835,6256,5604,22808,6777,1111,598,4067,5566,1399,466,1154,5906,6464,2624,5296,5601,581,5781,3717,10018,5598,6774,1386,7414,2242,6199,5914,2931,207,6654,5777,5295,10971,5747,10399,7297,5595,9021,2885,2534,1398,6778,2932,6776,7534,5594,3265,2549	MAPK8,ID1,RAF1,RAC1,SOCS2,RXRA,MAP2K1,MRAS,STAT5B,CHEK1,BCL2L1,LYN,PRKACA,CRKL,ATF1,CISH,RAP1A,SHC1,GATA2,PIK3R2,MAPK9,BAX,PTPN11,JAK2,BCL2L11,MAPK7,STAT3,ATF2,VCL,FES,RPS6KB2,RARA,GSK3A,AKT1,SOS1,PTPN6,PIK3R1,YWHAQ,PTK2,GNB2L1,TYK2,MAPK3,SOCS3,GRB2,FYN,CRK,STAT6,GSK3B,STAT5A,YWHAZ,MAPK1,HRAS,GAB1
WP2261	Signaling Pathways in Glioblastoma	0.00514018518276882	-5.27066617238801	80	42	0.0248815165876777	1688	4455	1030,2033,673,5607,7249,4763,5894,5604,4194,2064,1026,2309,898,5606,1031,4193,5296,1027,2065,54206,10253,1021,2956,5170,4303,207,5609,208,5295,672,5605,2260,5595,2885,5335,5608,5590,5594,3265,6416,2549,1029	CDKN2B,EP300,BRAF,MAP2K5,TSC2,NF1,RAF1,MAP2K1,MDM4,ERBB2,CDKN1A,FOXO3,CCNE1,MAP2K3,CDKN2C,MDM2,PIK3R2,CDKN1B,ERBB3,ERRFI1,SPRY2,CDK6,MSH6,PDPK1,FOXO4,AKT1,MAP2K7,AKT2,PIK3R1,BRCA1,MAP2K2,FGFR1,MAPK3,GRB2,PLCG1,MAP2K6,PRKCZ,MAPK1,HRAS,MAP2K4,GAB1,CDKN2A
WP2036	TWEAK Signaling Pathway	0.00537052268083621	-5.22683004170891	43	25	0.0148104265402844	1688	4455	5599,836,207,330,7186,5894,208,5879,1147,329,5595,840,7185,1499,3569,5601,3551,2932,3065,51330,4793,4791,841,5594,5970	MAPK8,CASP3,AKT1,BIRC3,TRAF2,RAF1,AKT2,RAC1,CHUK,BIRC2,MAPK3,CASP7,TRAF1,CTNNB1,IL6,MAPK9,IKBKB,GSK3B,HDAC1,TNFRSF12A,NFKBIB,NFKB2,CASP8,MAPK1,RELA
WP1984	Integrated Breast Cancer Pathway	0.00604831484409767	-5.10797558390402	152	73	0.0432464454976303	1688	4455	2033,836,23077,79877,7249,2475,4763,5879,6597,1147,580,4664,7465,4193,5906,1499,5296,4361,841,23411,1263,578,2241,207,2931,842,672,26284,7422,1605,27005,6009,5898,4087,3065,7517,657,4086,5594,10454,4089,9958,571,673,659,9175,5245,1111,8438,641,25,466,57223,581,84640,4091,79902,2956,6667,3156,3612,993,6237,79027,7175,8202,1647,5888,253959,6790,23613,196,5569	EP300,CASP3,MYCBP2,DCAKD,TSC2,MTOR,NF1,RAC1,SMARCA4,CHUK,BARD1,NAB1,WEE1,MDM2,RAP1A,CTNNB1,PIK3R2,MRE11A,CASP8,SIRT1,PLK3,BAK1,FER,AKT1,GSK3A,CASP9,BRCA1,ERAL1,VEGFA,DAG1,USP21,RHEB,RALA,SMAD2,HDAC1,XRCC3,BMPR1A,SMAD1,MAPK1,TAB1,SMAD4,USP15,BACH1,BRAF,BMPR2,MAP3K13,PHB,CHEK1,RAD54L,BLM,ABL1,ATF1,PPP4R3B,BAX,USP38,SMAD6,NUP85,MSH6,SP1,HMGCR,IMPA1,CDC25A,RRAS,ZNF655,TPR,NCOA3,GADD45A,RAD51,RALGAPA1,AURKA,ZMYND8,AHR,PKIA
WP197	Cholesterol biosynthesis	0.00632703029602159	-5.06292430045813	17	12	0.00710900473933649	1688	4455	4047,3157,3422,6721,6307,50814,2224,10654,6309,1717,3156,2222	LSS,HMGCS1,IDI1,SREBF2,MSMO1,NSDHL,FDPS,PMVK,SC5D,DHCR7,HMGCR,FDFT1
WP2374	Oncostatin M Signaling Pathway	0.00651993121689152	-5.03289145265574	63	34	0.0201421800947867	1688	4455	5599,836,1958,2475,5894,5604,6777,3727,5581,6464,3491,3572,3726,5601,6194,5781,1027,3717,253260,6774,5970,207,6654,5295,5605,7297,9021,5595,10401,2885,840,2185,5594,3265	MAPK8,CASP3,EGR1,MTOR,RAF1,MAP2K1,STAT5B,JUND,PRKCE,SHC1,CYR61,IL6ST,JUNB,MAPK9,RPS6,PTPN11,CDKN1B,JAK2,RICTOR,STAT3,RELA,AKT1,SOS1,PIK3R1,MAP2K2,TYK2,SOCS3,MAPK3,PIAS3,GRB2,CASP7,PTK2B,MAPK1,HRAS
WP313	Signaling of Hepatocyte Growth Factor Receptor	0.00659512854085016	-5.02142400235077	33	20	0.0118483412322275	1688	4455	5599,6654,5894,5604,5908,5747,5605,5921,5595,1399,2885,5906,1398,3688,5781,2185,5594,6774,3265,2549	MAPK8,SOS1,RAF1,MAP2K1,RAP1B,PTK2,MAP2K2,RASA1,MAPK3,CRKL,GRB2,RAP1A,CRK,ITGB1,PTPN11,PTK2B,MAPK1,STAT3,HRAS,GAB1
WP23	B Cell Receptor Signaling Pathway	0.00777705201853537	-4.85657793052542	158	75	0.0444312796208531	1688	4455	5599,5894,10096,5604,1147,3709,4067,898,1399,5164,890,1499,6464,3551,5296,5911,6194,10097,2969,1386,5970,1021,6655,26469,207,2931,4690,5777,842,1846,10014,5335,2534,1398,51363,2185,2932,6198,5594,2549,673,5966,4739,7410,10093,5532,123920,5581,10092,51564,896,5781,581,10018,6774,59339,5170,387,6654,5295,79837,5747,8394,9564,5605,5921,5595,2885,8396,840,3708,5534,3190,10109,493	MAPK8,RAF1,ACTR3,MAP2K1,CHUK,ITPR2,LYN,CCNE1,CRKL,PDK2,CCNA2,CTNNB1,SHC1,IKBKB,PIK3R2,RAP2A,RPS6,ACTR2,GTF2I,ATF2,RELA,CDK6,SOS2,PTPN18,AKT1,GSK3A,NCK1,PTPN6,CASP9,DUSP4,HDAC5,PLCG1,FYN,CRK,CHST15,PTK2B,GSK3B,RPS6KB1,MAPK1,GAB1,BRAF,REL,NEDD9,VAV2,ARPC4,PPP3CB,CMTM3,PRKCE,ARPC5,HDAC7,CCND3,PTPN11,BAX,BCL2L11,STAT3,PLEKHA2,PDPK1,RHOA,SOS1,PIK3R1,PIP4K2C,PTK2,PIP5K1A,BCAR1,MAP2K2,RASA1,MAPK3,GRB2,PIP4K2B,CASP7,ITPR1,PPP3R1,HNRNPK,ARPC2,ATP2B4
WP2263	Prostate Cancer	0.00796174706044986	-4.83310682325204	109	54	0.0319905213270142	1688	4455	5599,836,7249,2475,5894,5604,6597,1111,641,580,57492,57521,1399,466,4193,5906,581,5781,4361,253260,841,6774,2118,10253,2956,6667,993,207,6654,5591,842,5908,6604,3295,8289,672,6601,983,5605,6009,5921,5595,2885,4088,4087,1398,6599,1978,2185,5594,3265,2549,6602,10252	MAPK8,CASP3,TSC2,MTOR,RAF1,MAP2K1,SMARCA4,CHEK1,BLM,BARD1,ARID1B,RPTOR,CRKL,ATF1,MDM2,RAP1A,BAX,PTPN11,MRE11A,RICTOR,CASP8,STAT3,ETV4,SPRY2,MSH6,SP1,CDC25A,AKT1,SOS1,PRKDC,CASP9,RAP1B,SMARCD3,HSD17B4,ARID1A,BRCA1,SMARCC2,CDK1,MAP2K2,RHEB,RASA1,MAPK3,GRB2,SMAD3,SMAD2,CRK,SMARCC1,EIF4EBP1,PTK2B,MAPK1,HRAS,GAB1,SMARCD1,SPRY1
WP205	IL-7 Signaling Pathway	0.0080287612846439	-4.82472502386389	44	25	0.0148104265402844	1688	4455	207,6654,5894,5295,5604,6777,4067,2309,5605,5595,2885,8660,890,2534,6464,1213,581,2185,2932,6776,10018,6774,5594,3265,3659	AKT1,SOS1,RAF1,PIK3R1,MAP2K1,STAT5B,LYN,FOXO3,MAP2K2,MAPK3,GRB2,IRS2,CCNA2,FYN,SHC1,CLTC,BAX,PTK2B,GSK3B,STAT5A,BCL2L11,STAT3,MAPK1,HRAS,IRF1
WP382	MAPK signaling pathway	0.00817686665808581	-4.8064462508833	163	77	0.0456161137440758	1688	4455	5599,836,5607,4763,5894,5879,5604,51701,22808,5495,5566,3303,3727,1399,5906,3551,835,5494,140738,841,1386,6655,468,207,208,120892,842,8550,1846,9064,1398,1616,23118,5590,4296,6722,5533,5536,5594,10454,409,4137,9344,673,9175,839,7186,23162,8649,5532,1847,6788,5601,5062,5598,9020,1843,4214,5609,3164,5908,51295,5605,5921,3304,5595,2885,2768,840,1647,5608,5597,5534,4217,6416,1649,6197	MAPK8,CASP3,MAP2K5,NF1,RAF1,RAC1,MAP2K1,NLK,MRAS,PPM1B,PRKACA,HSPA1A,JUND,CRKL,RAP1A,IKBKB,CASP2,PPM1A,TMEM37,CASP8,ATF2,SOS2,ATF4,AKT1,AKT2,LRRK2,CASP9,MAPKAPK5,DUSP4,MAP3K6,CRK,DAXX,TAB2,PRKCZ,MAP3K11,SRF,PPP3CC,PPP5C,MAPK1,TAB1,ARRB2,MAPT,TAOK2,BRAF,MAP3K13,CASP6,TRAF2,MAPK8IP3,LAMTOR3,PPP3CB,DUSP5,STK3,MAPK9,PAK2,MAPK7,MAP3K14,DUSP1,MAP3K1,MAP2K7,NR4A1,RAP1B,ECSIT,MAP2K2,RASA1,HSPA1B,MAPK3,GRB2,GNA12,CASP7,GADD45A,MAP2K6,MAPK6,PPP3R1,MAP3K5,MAP2K4,DDIT3,RPS6KA3
WP2324	AGE/RAGE pathway	0.00834115740351902	-4.78655329483981	66	35	0.0207345971563981	1688	4455	5599,836,3958,5894,5879,5604,1147,6777,6464,3551,51135,5601,3717,841,6774,5970,1386,6667,387,207,4303,842,7430,1729,5595,4088,4087,3643,1650,3091,5590,6776,6093,5594,114609	MAPK8,CASP3,LGALS3,RAF1,RAC1,MAP2K1,CHUK,STAT5B,SHC1,IKBKB,IRAK4,MAPK9,JAK2,CASP8,STAT3,RELA,ATF2,SP1,RHOA,AKT1,FOXO4,CASP9,EZR,DIAPH1,MAPK3,SMAD3,SMAD2,INSR,DDOST,HIF1A,PRKCZ,STAT5A,ROCK1,MAPK1,TIRAP
WP1425	BMP signalling and regulation	0.010131796080288	-4.59207667334924	12	9	0.00533175355450237	1688	4455	659,9241,10766,657,4086,4091,57154,10140,4089	BMPR2,NOG,TOB2,BMPR1A,SMAD1,SMAD6,SMURF1,TOB1,SMAD4
WP1471	TOR signaling	0.0103916412334359	-4.56675352355121	34	20	0.0118483412322275	1688	4455	207,7249,2475,5565,5879,5562,79109,64121,5571,8408,6009,54541,57521,51422,1978,10325,6198,253260,58528,64223	AKT1,TSC2,MTOR,PRKAB2,RAC1,PRKAA1,MAPKAP1,RRAGC,PRKAG1,ULK1,RHEB,DDIT4,RPTOR,PRKAG2,EIF4EBP1,RRAGB,RPS6KB1,RICTOR,RRAGD,MLST8
WP28	Selenium Metabolism and Selenoproteins	0.0124186889790349	-4.38855276529193	43	24	0.014218009478673	1688	4455	7296,6670,85465,54952,83642,1734,6156,6414,114112,1390,280636,8991,60678,51714,51091,5970,2876,4780,57190,10587,6667,51540,2879,1491	TXNRD1,SP3,EPT1,TRNAU1AP,SELO,DIO2,RPL30,SEPP1,TXNRD3,CREM,C11orf31,SELENBP1,EEFSEC,SELT,SEPSECS,RELA,GPX1,NFE2L2,SEPN1,TXNRD2,SP1,SCLY,GPX4,CTH
WP2011	SREBF and miR33 in cholesterol and lipid homeostasis	0.0124845421418064	-4.38326402858554	18	12	0.00710900473933649	1688	4455	23411,3157,6721,2475,51548,51586,5562,5465,2194,6319,10891,3156	SIRT1,HMGCS1,SREBF2,MTOR,SIRT6,MED15,PRKAA1,PPARA,FASN,SCD,PPARGC1A,HMGCR
WP673	ErbB signaling pathway	0.0125984955536478	-4.37417787265766	54	29	0.0171800947867299	1688	4455	5599,685,5609,5163,6654,2475,4690,7039,5604,2064,5747,1026,10298,2885,25,5335,4193,1398,1978,2069,2932,1027,6776,6198,2065,10018,5594,3265,2549	MAPK8,BTC,MAP2K7,PDK1,SOS1,MTOR,NCK1,TGFA,MAP2K1,ERBB2,PTK2,CDKN1A,PAK4,GRB2,ABL1,PLCG1,MDM2,CRK,EIF4EBP1,EREG,GSK3B,CDKN1B,STAT5A,RPS6KB1,ERBB3,BCL2L11,MAPK1,HRAS,GAB1
WP363	Wnt Signaling Pathway NetPath	0.0175344797092867	-4.043586067385	115	55	0.0325829383886256	1688	4455	51588,2033,5599,3728,6908,8325,5894,6929,5879,5076,6662,51701,8454,324,1488,2535,1452,7341,7474,56998,1499,6925,5601,7020,1739,30851,4040,1856,8321,387,207,8322,1454,4035,2274,1742,23401,1857,995,983,8324,260425,5595,22943,4088,80319,817,10023,8326,2932,7855,5594,409,4089,1487	PIAS4,EP300,MAPK8,JUP,TBP,FZD8,RAF1,TCF3,RAC1,PAX2,SOX9,NLK,CUL1,APC,CTBP2,FZD2,CSNK1A1,SUMO1,WNT5A,CTNNBIP1,CTNNB1,TCF4,MAPK9,TFAP2A,DLG1,TAX1BP3,LRP6,DVL2,FZD1,RHOA,AKT1,FZD4,CSNK1E,LRP1,FHL2,DLG4,FRAT2,DVL3,CDC25C,CDK1,FZD7,MAGI3,MAPK3,DKK1,SMAD3,CXXC4,CAMK2D,FRAT1,FZD9,GSK3B,FZD5,MAPK1,ARRB2,SMAD4,CTBP1
WP2290	RalA downstream regulated genes	0.0180101866045094	-4.01681775868696	9	7	0.00414691943127962	1688	4455	5898,55770,8531,10928,5881,5879,149371	RALA,EXOC2,YBX3,RALBP1,RAC3,RAC1,EXOC8
WP185	Integrin-mediated cell adhesion	0.019133064852656	-3.95633729651433	99	48	0.028436018957346	1688	4455	673,5607,10580,5894,5879,7410,5604,6414,3693,10298,5881,5606,824,7791,5906,7408,6464,5296,5062,5598,7414,9475,5170,207,6654,208,726,5908,3678,826,5747,857,9564,5605,2885,2534,1398,5608,5597,23473,3673,3688,11132,3685,6093,5594,3265,823	BRAF,MAP2K5,SORBS1,RAF1,RAC1,VAV2,MAP2K1,SEPP1,ITGB5,PAK4,RAC3,MAP2K3,CAPN2,ZYX,RAP1A,VASP,SHC1,PIK3R2,PAK2,MAPK7,VCL,ROCK2,PDPK1,AKT1,SOS1,AKT2,CAPN5,RAP1B,ITGA5,CAPNS1,PTK2,CAV1,BCAR1,MAP2K2,GRB2,FYN,CRK,MAP2K6,MAPK6,CAPN7,ITGA2,ITGB1,CAPN10,ITGAV,ROCK1,MAPK1,HRAS,CAPN1
WP244	Alpha6-Beta4 Integrin Signaling Pathway	0.0194086335253781	-3.94203728482669	69	35	0.0207345971563981	1688	4455	836,2475,5879,2064,1026,7531,25,667,3692,6464,5296,8503,3913,1977,387,3915,207,5295,10971,5747,5339,55914,7525,1832,3921,2885,8660,4088,4087,2534,4486,1978,7534,7533,2810	CASP3,MTOR,RAC1,ERBB2,CDKN1A,YWHAE,ABL1,DST,EIF6,SHC1,PIK3R2,PIK3R3,LAMB2,EIF4E,RHOA,LAMC1,AKT1,PIK3R1,YWHAQ,PTK2,PLEC,ERBB2IP,YES1,DSP,RPSA,GRB2,IRS2,SMAD3,SMAD2,FYN,MST1R,EIF4EBP1,YWHAZ,YWHAH,SFN
WP2253	pilocytic astrocytoma	0.0205654979033695	-3.88414046639082	4	4	0.0023696682464455	1688	4455	2885,4763,6654,5781	GRB2,NF1,SOS1,PTPN11
WP2203	TSLP Signaling Pathway	0.0215907392183779	-3.83549079611716	38	21	0.0124407582938389	1688	4455	5599,207,2475,5604,6777,5605,5595,55361,1154,1978,3569,6778,5601,6194,5781,3717,6776,4791,6774,5594,5970	MAPK8,AKT1,MTOR,MAP2K1,STAT5B,MAP2K2,MAPK3,PI4K2A,CISH,EIF4EBP1,IL6,STAT6,MAPK9,RPS6,PTPN11,JAK2,STAT5A,NFKB2,STAT3,MAPK1,RELA
WP734	Serotonin Receptor 4/6/7 and NR3C Signaling	0.0223372748025169	-3.80149848013591	19	12	0.00710900473933649	1688	4455	2778,466,673,5906,1958,2908,5604,6722,9252,5594,5605,5595	GNAS,ATF1,BRAF,RAP1A,EGR1,NR3C1,MAP2K1,SRF,RPS6KA5,MAPK1,MAP2K2,MAPK3
WP78	TCA Cycle	0.0226222226461085	-3.78882255290438	17	11	0.00651658767772512	1688	4455	50,8802,6391,3419,4191,1431,8801,3418,3420,1743,6392	ACO2,SUCLG1,SDHC,IDH3A,MDH2,CS,SUCLG2,IDH2,IDH3B,DLST,SDHD
WP405	Eukaryotic Transcription Initiation	0.0283293349499981	-3.56385744053004	41	22	0.0130331753554502	1688	4455	6884,6877,5438,5436,2071,6908,5440,171568,51728,5430,5432,4331,2963,5434,6879,6883,84172,2068,55703,2959,6878,64425	TAF13,TAF5,POLR2I,POLR2G,ERCC3,TBP,POLR2K,POLR3H,POLR3K,POLR2A,POLR2C,MNAT1,GTF2F2,POLR2E,TAF7,TAF12,POLR1B,ERCC2,POLR3B,GTF2B,TAF6,POLR1E
WP2272	Pathogenic Escherichia coli infection	0.0326411700640097	-3.42218090197942	55	28	0.0165876777251185	1688	4455	9076,387,7280,81873,71,4690,10383,10971,7430,4691,10093,10552,25,2534,1499,10092,8976,3688,9181,7534,60,2017,6093,10109,3875,9475,203068,10381	CLDN1,RHOA,TUBB2A,ARPC5L,ACTG1,NCK1,TUBB4B,YWHAQ,EZR,NCL,ARPC4,ARPC1A,ABL1,FYN,CTNNB1,ARPC5,WASL,ITGB1,ARHGEF2,YWHAZ,ACTB,CTTN,ROCK1,ARPC2,KRT18,ROCK2,TUBB,TUBB3
WP2355	Corticotropin-releasing hormone	0.0337857889702828	-3.387715009571	90	43	0.0254739336492891	1688	4455	5599,836,673,3728,5894,5604,2782,3606,2870,2355,2783,3727,1499,10681,2781,6925,3726,2354,5601,7020,5584,3320,5970,2771,31,6667,387,207,3164,842,5908,5747,2767,10155,5595,2770,2778,5335,2081,2932,4217,5594,409	MAPK8,CASP3,BRAF,JUP,RAF1,MAP2K1,GNB1,IL18,GRK6,FOSL2,GNB2,JUND,CTNNB1,GNB5,GNAZ,TCF4,JUNB,FOSB,MAPK9,TFAP2A,PRKCI,HSP90AA1,RELA,GNAI2,ACACA,SP1,RHOA,AKT1,NR4A1,CASP9,RAP1B,PTK2,GNA11,TRIM28,MAPK3,GNAI1,GNAS,PLCG1,ERN1,GSK3B,MAP3K5,MAPK1,ARRB2
WP127	IL-5 Signaling Pathway	0.0342066216805217	-3.37533603726529	69	34	0.0201421800947867	1688	4455	5894,5879,6777,4067,2309,1399,6464,1499,8651,896,5296,5601,581,5781,1785,1027,3717,5292,6774,1386,2931,207,5777,5295,6659,5605,5595,2885,2932,2185,6776,7534,5594,3265	RAF1,RAC1,STAT5B,LYN,FOXO3,CRKL,SHC1,CTNNB1,SOCS1,CCND3,PIK3R2,MAPK9,BAX,PTPN11,DNM2,CDKN1B,JAK2,PIM1,STAT3,ATF2,GSK3A,AKT1,PTPN6,PIK3R1,SOX4,MAP2K2,MAPK3,GRB2,GSK3B,PTK2B,STAT5A,YWHAZ,MAPK1,HRAS
WP134	Pentose Phosphate Pathway	0.0378239975356298	-3.27481152235212	8	6	0.00355450236966825	1688	4455	6120,25796,6888,2539,22934,5226	RPE,PGLS,TALDO1,G6PD,RPIA,PGD
WP2018	RANKL/RANK Signaling Pathway	0.0456156611495773	-3.0875041751633	54	27	0.0159952606635071	1688	4455	5599,207,5609,2475,7186,208,5295,5879,5604,2274,1147,5747,4067,5595,5335,7185,8878,23118,5608,3551,5601,5296,4286,4791,5594,10454,5970	MAPK8,AKT1,MAP2K7,MTOR,TRAF2,AKT2,PIK3R1,RAC1,MAP2K1,FHL2,CHUK,PTK2,LYN,MAPK3,PLCG1,TRAF1,SQSTM1,TAB2,MAP2K6,IKBKB,MAPK9,PIK3R2,MITF,NFKB2,MAPK1,TAB1,RELA
WP2035	FSH signaling pathway	0.0464957720624183	-3.06839389391146	27	15	0.00888625592417062	1688	4455	207,7249,2475,1978,5894,6194,6446,6198,2870,5594,5566,26060,6009,5595,6199	AKT1,TSC2,MTOR,EIF4EBP1,RAF1,RPS6,SGK1,RPS6KB1,GRK6,MAPK1,PRKACA,APPL1,RHEB,MAPK3,RPS6KB2
WP2363	Gastric cancer network 2	0.0523633840754447	-2.94954770909988	34	18	0.0106635071090047	1688	4455	55593,5984,5983,92140,79075,157769,3930,6638,55215,7153,25909,84823,29089,1499,29028,10153,27101,11065	OTUD5,RFC4,RFC3,MTDH,DSCC1,FAM91A1,LBR,SNRPN,FANCI,TOP2A,AHCTF1,LMNB2,UBE2T,CTNNB1,ATAD2,CEBPZ,CACYBP,UBE2C
WP2371	Parkinsons Disease Pathway	0.0603051833887035	-2.80833721893168	39	20	0.0118483412322275	1688	4455	5071,836,7317,839,7332,842,120892,2812,118424,11315,898,6622,840,9246,6311,835,51465,317,7314,7327	PARK2,CASP3,UBA1,CASP6,UBE2L3,CASP9,LRRK2,GP1BB,UBE2J2,PARK7,CCNE1,SNCA,CASP7,UBE2L6,ATXN2,CASP2,UBE2J1,APAF1,UBB,UBE2G2
WP384	Apoptosis Modulation by HSP70	0.0608492978146166	-2.79935499922707	19	11	0.00651658767772512	1688	4455	836,840,839,842,835,9131,317,841,3303,3304,4214	CASP3,CASP7,CASP6,CASP9,CASP2,AIFM1,APAF1,CASP8,HSPA1A,HSPA1B,MAP3K1
WP268	Notch Signaling Pathway	0.0621822542573523	-2.77768562127191	46	23	0.0136255924170616	1688	4455	3280,6868,54567,2648,51107,3955,1857,1488,83464,1387,9253,182,23220,5664,3065,3516,9794,23385,1487,3066,8650,1856,55534	HES1,ADAM17,DLL4,KAT2A,APH1A,LFNG,DVL3,CTBP2,APH1B,CREBBP,NUMBL,JAG1,DTX4,PSEN2,HDAC1,RBPJ,MAML1,NCSTN,CTBP1,HDAC2,NUMB,DVL2,MAML3
WP2038	Regulation of Microtubule Cytoskeleton	0.0672764521614774	-2.69894499714724	44	22	0.0130331753554502	1688	4455	90102,161742,207,5786,5879,7204,814,10420,324,11004,9212,5566,983,1073,25,6249,3984,1808,2932,6093,6774,4137	PHLDB2,SPRED1,AKT1,PTPRA,RAC1,TRIO,CAMK4,TESK2,APC,KIF2C,AURKB,PRKACA,CDK1,CFL2,ABL1,CLIP1,LIMK1,DPYSL2,GSK3B,ROCK1,STAT3,MAPT
WP259	Nifedipine Activity	0.0717043275579254	-2.63520417674152	5	4	0.0023696682464455	1688	4455	2185,5111,5594,5604	PTK2B,PCNA,MAPK1,MAP2K1
WP2361	Gastric cancer network 1	0.0728323724504373	-2.6195947461018	42	21	0.0124407582938389	1688	4455	8367,4605,56992,9585,324,8368,8360,121504,8365,7153,286826,8294,8366,8364,57122,352954,6790,55125,3020,11065,8209	HIST1H4E,MYBL2,KIF15,KIF20B,APC,HIST1H4L,HIST1H4D,HIST4H4,HIST1H4H,TOP2A,LIN9,HIST1H4I,HIST1H4B,HIST1H4C,NUP107,GATS,AURKA,CEP192,H3F3A,UBE2C,C21orf33
WP1434	Osteopontin Signaling	0.0754563693681701	-2.58420067893277	11	7	0.00414691943127962	1688	4455	1147,9020,5594,5970,3551,5595,5604	CHUK,MAP3K14,MAPK1,RELA,IKBKB,MAPK3,MAP2K1
WP236	Adipogenesis	0.0761610807266121	-2.57490469838684	131	58	0.0343601895734597	1688	4455	4282,6517,2034,6256,2971,4205,6319,6777,1050,1026,64900,1592,4000,8651,1499,2624,3572,5106,6774,8204,1052,6667,8321,26580,5914,7480,2626,2908,5468,5465,100271849,434,4209,1316,7025,6773,9021,10269,2303,4088,8660,3399,5467,57761,1647,3091,3569,6778,1874,4616,25937,1675,6776,3159,9611,10891,196,1649	MIF,SLC2A4,EPAS1,RXRA,GTF3A,MEF2A,SCD,STAT5B,CEBPA,CDKN1A,LPIN3,CYP26A1,LMNA,SOCS1,CTNNB1,GATA2,IL6ST,PCK2,STAT3,NRIP1,CEBPD,SP1,FZD1,BSCL2,RARA,WNT10B,GATA4,NR3C1,PPARG,PPARA,MEF2B,ASIP,MEF2D,KLF6,NR2F1,STAT2,SOCS3,ZMPSTE24,FOXC2,SMAD3,IRS2,ID3,PPARD,TRIB3,GADD45A,HIF1A,IL6,STAT6,E2F4,GADD45B,WWTR1,CFD,STAT5A,HMGA1,NCOR1,PPARGC1A,AHR,DDIT3
WP1528	Physiological and Pathological Hypertrophy  of the Heart	0.0770401165144272	-2.56342899910469	24	13	0.00770142180094787	1688	4455	5599,5581,817,387,2626,3572,5879,1489,4776,5532,6774,5594,5606	MAPK8,PRKCE,CAMK2D,RHOA,GATA4,IL6ST,RAC1,CTF1,NFATC4,PPP3CB,STAT3,MAPK1,MAP2K3
WP26	Signal Transduction of S1P Receptor	0.0770401165144272	-2.56342899910469	24	13	0.00770142180094787	1688	4455	207,53637,208,5597,8877,427,5598,5594,56848,2773,2771,5595,2770	AKT1,S1PR5,AKT2,MAPK6,SPHK1,ASAH1,MAPK7,MAPK1,SPHK2,GNAI3,GNAI2,MAPK3,GNAI1
WP561	Heme Biosynthesis	0.0774516193982166	-2.55810180338734	9	6	0.00355450236966825	1688	4455	210,7390,5498,1371,7389,211	ALAD,UROS,PPOX,CPOX,UROD,ALAS1
WP531	Mismatch repair	0.0774516193982166	-2.55810180338734	9	6	0.00355450236966825	1688	4455	9156,3978,5981,5111,5424,2956	EXO1,LIG1,RFC1,PCNA,POLD1,MSH6
WP2525	Trans-sulfuration and one carbon metabolism	0.0830420896619728	-2.48840769535839	31	16	0.00947867298578199	1688	4455	29968,2729,25902,4144,23382,2937,10797,7298,1719,6472,200895,10768,441024,5723,4522,1491	PSAT1,GCLC,MTHFD1L,MAT2A,AHCYL2,GSS,MTHFD2,TYMS,DHFR,SHMT2,DHFRL1,AHCYL1,MTHFD2L,PSPH,MTHFD1,CTH
WP357	Fatty Acid Biosynthesis	0.083314336915595	-2.48513463278701	22	12	0.00710900473933649	1688	4455	2180,5091,2181,1892,2194,10449,51102,6319,55825,2182,55862,31	ACSL1,PC,ACSL3,ECHS1,FASN,ACAA2,MECR,SCD,PECR,ACSL4,ECHDC1,ACACA
WP516	Hypertrophy Model	0.0901249562251917	-2.4065581690893	20	11	0.00651658767772512	1688	4455	3475,3491,102,1978,9948,467,3606,7422,1977,11072,3727	IFRD1,CYR61,ADAM10,EIF4EBP1,WDR1,ATF3,IL18,VEGFA,EIF4E,DUSP14,JUND
WP400	p38 MAPK Signaling Pathway	0.100783484940105	-2.29478077664799	34	17	0.0100710900473934	1688	4455	3150,7186,5879,8550,4209,9252,2885,6464,1616,5608,4293,4217,1386,3265,6416,1649,4214	HMGN1,TRAF2,RAC1,MAPKAPK5,MEF2D,RPS6KA5,GRB2,SHC1,DAXX,MAP2K6,MAP3K9,MAP3K5,ATF2,HRAS,MAP2K4,DDIT3,MAP3K1
WP1403	AMPK signaling	0.117139841032873	-2.14438683539097	68	31	0.0183649289099526	1688	4455	6517,207,7249,2475,208,5565,84254,92335,5295,5562,2194,79602,5571,1375,1026,891,57521,890,3643,51422,1938,1994,1978,5296,8503,6198,51094,5567,31,6199,3156	SLC2A4,AKT1,TSC2,MTOR,AKT2,PRKAB2,CAMKK1,STRADA,PIK3R1,PRKAA1,FASN,ADIPOR2,PRKAG1,CPT1B,CDKN1A,CCNB1,RPTOR,CCNA2,INSR,PRKAG2,EEF2,ELAVL1,EIF4EBP1,PIK3R2,PIK3R3,RPS6KB1,ADIPOR1,PRKACB,ACACA,RPS6KB2,HMGCR
WP500	Glycogen Metabolism	0.118901977313974	-2.12945584536502	37	18	0.0106635071090047	1688	4455	2632,5236,2931,7360,5837,5520,808,5519,5529,5255,5524,2932,5527,5521,5256,178,5528,5261	GBE1,PGM1,GSK3A,UGP2,PYGM,PPP2R2A,CALM3,PPP2R1B,PPP2R5E,PHKA1,PPP2R4,GSK3B,PPP2R5C,PPP2R2B,PHKA2,AGL,PPP2R5D,PHKG2
WP534	Glycolysis and Gluconeogenesis	0.122678222807059	-2.09819042625233	49	23	0.0136255924170616	1688	4455	5160,2597,6517,2026,4191,5315,8050,51660,25874,5091,2806,5211,230,226,2027,4190,5224,3098,5223,3101,5214,7167,3945	PDHA1,GAPDH,SLC2A4,ENO2,MDH2,PKM,PDHX,MPC1,MPC2,PC,GOT2,PFKL,ALDOC,ALDOA,ENO3,MDH1,PGAM2,HK1,PGAM1,HK3,PFKP,TPI1,LDHB
WP391	Mitochondrial Gene Expression	0.123273289492467	-2.09335152251097	12	7	0.00414691943127962	1688	4455	814,3054,4899,51106,2101,10891,6667	CAMK4,HCFC1,NRF1,TFB1M,ESRRA,PPARGC1A,SP1
WP254	Apoptosis	0.124795482081082	-2.08107902497547	83	37	0.0219194312796209	1688	4455	836,1676,839,7186,1147,598,3661,329,599,4193,5366,3551,581,835,3660,841,10018,5970,4214,578,330,207,5295,842,665,8743,56616,837,3663,840,7185,317,4793,666,6416,1029,3659	CASP3,DFFA,CASP6,TRAF2,CHUK,BCL2L1,IRF3,BIRC2,BCL2L2,MDM2,PMAIP1,IKBKB,BAX,CASP2,IRF2,CASP8,BCL2L11,RELA,MAP3K1,BAK1,BIRC3,AKT1,PIK3R1,CASP9,BNIP3L,TNFSF10,DIABLO,CASP4,IRF5,CASP7,TRAF1,APAF1,NFKBIB,BOK,MAP2K4,CDKN2A,IRF1
WP1742	TP53 network	0.138243112302373	-1.97874146041844	19	10	0.00592417061611374	1688	4455	25,4193,1647,5366,581,8743,1026,666,1029,7341	ABL1,MDM2,GADD45A,PMAIP1,BAX,TNFSF10,CDKN1A,BOK,CDKN2A,SUMO1
WP288	NLR proteins	0.142532277049191	-1.94818679931359	8	5	0.00296208530805687	1688	4455	5599,1147,55914,958,3551	MAPK8,CHUK,ERBB2IP,CD40,IKBKB
WP2059	Alzheimers Disease	0.142828168469865	-1.94611299033716	79	35	0.0207345971563981	1688	4455	836,102,23621,322,3028,9451,808,5532,3709,824,488,5664,841,8883,11261,6868,2597,51107,842,4035,3710,5595,6622,840,3416,3708,2081,5534,2932,5533,317,5594,23385,4137,823	CASP3,ADAM10,BACE1,APBB1,HSD17B10,EIF2AK3,CALM3,PPP3CB,ITPR2,CAPN2,ATP2A2,PSEN2,CASP8,NAE1,CHP1,ADAM17,GAPDH,APH1A,CASP9,LRP1,ITPR3,MAPK3,SNCA,CASP7,IDE,ITPR1,ERN1,PPP3R1,GSK3B,PPP3CC,APAF1,MAPK1,NCSTN,MAPT,CAPN1
WP314	FAS pathway and Stress induction of HSP regulation	0.148931606665853	-1.90426809408203	38	18	0.0106635071090047	1688	4455	5599,836,1676,839,7867,5591,842,4000,84823,840,1616,5062,317,841,6416,11124,4214,6709	MAPK8,CASP3,DFFA,CASP6,MAPKAPK3,PRKDC,CASP9,LMNA,LMNB2,CASP7,DAXX,PAK2,APAF1,CASP8,MAP2K4,FAF1,MAP3K1,SPTAN1
WP2112	IL17 signaling pathway	0.153159952645397	-1.87627246155697	31	15	0.00888625592417062	1688	4455	55540,207,3551,84818,23765,2932,3717,4793,9020,6774,5970,5594,1052,5595,6667	IL17RB,AKT1,IKBKB,IL17RC,IL17RA,GSK3B,JAK2,NFKBIB,MAP3K14,STAT3,RELA,MAPK1,CEBPD,MAPK3,SP1
WP325	Triacylglyceride Synthesis	0.154991955553288	-1.86438206306593	24	12	0.00710900473933649	1688	4455	2710,8611,55326,56895,8443,84649,8612,10554,56894,57678,8694,2819	GK,PLPP1,AGPAT5,AGPAT4,GNPAT,DGAT2,PLPP2,AGPAT1,AGPAT3,GPAM,DGAT1,GPD1
WP428	Wnt Signaling Pathway	0.156477974173798	-1.85484001901028	60	27	0.0159952606635071	1688	4455	387,7480,5048,8325,1454,7976,5879,1857,7481,324,2535,8324,7474,5581,5529,1499,10023,896,8326,5601,5590,5584,2932,5527,7855,1856,8321	RHOA,WNT10B,PAFAH1B1,FZD8,CSNK1E,FZD3,RAC1,DVL3,WNT11,APC,FZD2,FZD7,WNT5A,PRKCE,PPP2R5E,CTNNB1,FRAT1,CCND3,FZD9,MAPK9,PRKCZ,PRKCI,GSK3B,PPP2R5C,FZD5,DVL2,FZD1
WP410	Diurnally regulated genes with circadian orthologs	0.160743805387328	-1.82794345230007	48	22	0.0130331753554502	1688	4455	7360,5507,1982,5685,51663,5281,9709,7341,694,3422,8031,23118,5187,2120,406,51582,1408,9575,1407,5813,10140,10381	UGP2,PPP1R3C,EIF4G2,PSMA4,ZFR,PIGF,HERPUD1,SUMO1,BTG1,IDI1,NCOA4,TAB2,PER1,ETV6,ARNTL,AZIN1,CRY2,CLOCK,CRY1,PURA,TOB1,TUBB3
WP422	MAPK Cascade	0.167063540923459	-1.78938105435967	29	14	0.00829383886255924	1688	4455	4215,673,5609,6237,5608,5894,5604,5594,3265,5605,6416,5606,5595,4214	MAP3K3,BRAF,MAP2K7,RRAS,MAP2K6,RAF1,MAP2K1,MAPK1,HRAS,MAP2K2,MAP2K4,MAP2K3,MAPK3,MAP3K1
WP262	EBV LMP1 signaling	0.169758363267873	-1.77337924561044	22	11	0.00651658767772512	1688	4455	9260,4215,5599,7185,3551,1147,3320,9020,4791,5970,5594	PDLIM7,MAP3K3,MAPK8,TRAF1,IKBKB,CHUK,HSP90AA1,MAP3K14,NFKB2,RELA,MAPK1
WP47	Hedgehog Signaling Pathway	0.169758363267873	-1.77337924561044	22	11	0.00651658767772512	1688	4455	1387,2737,1859,51715,5727,27148,10284,25942,891,983,2619	CREBBP,GLI3,DYRK1A,RAB23,PTCH1,STK36,SAP18,SIN3A,CCNB1,CDK1,GAS1
WP1601	Fluoropyrimidine Activity	0.175997457409091	-1.73728573058759	34	16	0.00947867298578199	1688	4455	23583,5471,7378,6240,9429,6241,2030,1890,6996,2356,7298,1719,7372,7517,1806,2068	SMUG1,PPAT,UPP1,RRM1,ABCG2,RRM2,SLC29A1,TYMP,TDG,FPGS,TYMS,DHFR,UMPS,XRCC3,DPYD,ERCC2
WP2447	Amyotrophic lateral sclerosis (ALS)	0.175997457409091	-1.73728573058759	34	16	0.00947867298578199	1688	4455	836,5879,842,5868,5532,598,9973,5605,847,1616,5608,581,5533,317,4217,2876	CASP3,RAC1,CASP9,RAB5A,PPP3CB,BCL2L1,CCS,MAP2K2,CAT,DAXX,MAP2K6,BAX,PPP3CC,APAF1,MAP3K5,GPX1
WP712	Estrogen signaling pathway	0.18636126837859	-1.68006818599	20	10	0.00592417061611374	1688	4455	2778,673,207,5601,5604,2782,2852,5566,5594,6667	GNAS,BRAF,AKT1,MAPK9,MAP2K1,GNB1,GPER1,PRKACA,MAPK1,SP1
WP1772	Apoptosis Modulation and Signaling	0.201222697463508	-1.60334303666436	79	34	0.0201421800947867	1688	4455	5599,578,836,330,57448,1676,839,638,842,2021,56616,8743,826,598,329,599,5595,840,1616,5366,3551,8567,581,835,664,317,9020,841,8793,10018,4217,666,1029,51155	MAPK8,BAK1,CASP3,BIRC3,BIRC6,DFFA,CASP6,BIK,CASP9,ENDOG,DIABLO,TNFSF10,CAPNS1,BCL2L1,BIRC2,BCL2L2,MAPK3,CASP7,DAXX,PMAIP1,IKBKB,MADD,BAX,CASP2,BNIP3,APAF1,MAP3K14,CASP8,TNFRSF10D,BCL2L11,MAP3K5,BOK,CDKN2A,HN1
WP1971	Integrated Cancer pathway	0.215381394896664	-1.53534489265766	35	16	0.00947867298578199	1688	4455	4088,836,993,4193,4087,207,842,581,4361,1111,672,841,641,580,983,2956	SMAD3,CASP3,CDC25A,MDM2,SMAD2,AKT1,CASP9,BAX,MRE11A,CHEK1,BRCA1,CASP8,BLM,BARD1,CDK1,MSH6
WP1530	miRNA Regulation of DNA Damage Response	0.223883099114801	-1.4966312423051	9	5	0.00296208530805687	1688	4455	84126,4361,5981,55367,166979	ATRIP,MRE11A,RFC1,PIDD1,CDC20B
WP528	Acetylcholine Synthesis	0.249945313189492	-1.38651313229059	7	4	0.0023696682464455	1688	4455	5160,10400,5130,1119	PDHA1,PEMT,PCYT1A,CHKA
WP399	Wnt Signaling Pathway and Pluripotency	0.249987012850282	-1.38634631106814	101	42	0.0248815165876777	1688	4455	2033,5048,8325,5520,51701,324,1488,2535,5519,7474,1387,5581,1499,896,5601,5584,4040,5521,1856,8321,387,7480,8322,1454,7976,120892,7481,1857,6934,8324,5467,5529,10023,5524,8326,5590,2932,5527,1500,7855,6416,1487	EP300,PAFAH1B1,FZD8,PPP2R2A,NLK,APC,CTBP2,FZD2,PPP2R1B,WNT5A,CREBBP,PRKCE,CTNNB1,CCND3,MAPK9,PRKCI,LRP6,PPP2R2B,DVL2,FZD1,RHOA,WNT10B,FZD4,CSNK1E,FZD3,LRRK2,WNT11,DVL3,TCF7L2,FZD7,PPARD,PPP2R5E,FRAT1,PPP2R4,FZD9,PRKCZ,GSK3B,PPP2R5C,CTNND1,FZD5,MAP2K4,CTBP1
WP1544	MicroRNAs in cardiomyocyte hypertrophy	0.259801177908705	-1.3478386408502	109	45	0.0266587677725118	1688	4455	5599,5607,2475,5894,5879,5604,808,1147,5532,2535,5606,7474,1154,1499,3572,51564,3551,5296,8503,4040,1489,9020,5598,6774,9475,8321,5170,387,5609,207,2626,208,5295,5605,10014,5595,817,9759,5608,2932,4776,6093,5594,10454,6416	MAPK8,MAP2K5,MTOR,RAF1,RAC1,MAP2K1,CALM3,CHUK,PPP3CB,FZD2,MAP2K3,WNT5A,CISH,CTNNB1,IL6ST,HDAC7,IKBKB,PIK3R2,PIK3R3,LRP6,CTF1,MAP3K14,MAPK7,STAT3,ROCK2,FZD1,PDPK1,RHOA,MAP2K7,AKT1,GATA4,AKT2,PIK3R1,MAP2K2,HDAC5,MAPK3,CAMK2D,HDAC4,MAP2K6,GSK3B,NFATC4,ROCK1,MAPK1,TAB1,MAP2K4
WP51	Regulation of Actin Cytoskeleton	0.26652275140762	-1.32229566788461	145	59	0.0349526066350711	1688	4455	10163,85464,673,4659,71,8936,5894,8826,5879,5604,30849,324,22808,55740,4628,10298,5881,55845,10092,9138,5296,5062,8503,6548,22800,7414,9475,6655,54961,10152,387,6237,6654,5295,2257,79837,7430,87,5747,8394,9564,7114,5605,1073,2260,10458,5595,2768,2934,8396,1398,3984,5597,138429,60,6093,5594,10672,2245	WASF2,SSH2,BRAF,PPP1R12A,ACTG1,WASF1,RAF1,IQGAP1,RAC1,MAP2K1,PIK3R4,APC,MRAS,ENAH,MYH10,PAK4,RAC3,BRK1,ARPC5,ARHGEF1,PIK3R2,PAK2,PIK3R3,SLC9A1,RRAS2,VCL,ROCK2,SOS2,SSH3,ABI2,RHOA,RRAS,SOS1,PIK3R1,FGF12,PIP4K2C,EZR,ACTN1,PTK2,PIP5K1A,BCAR1,TMSB4X,MAP2K2,CFL2,FGFR1,BAIAP2,MAPK3,GNA12,GSN,PIP4K2B,CRK,LIMK1,MAPK6,PIP5KL1,ACTB,ROCK1,MAPK1,GNA13,FGD1
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling	0.293512011389958	-1.22583671588372	17	8	0.004739336492891	1688	4455	2626,5894,3708,5604,6722,5594,5605,5595	GATA4,RAF1,ITPR1,MAP2K1,SRF,MAPK1,MAP2K2,MAPK3
WP53	Id Signaling Pathway	0.299948328400868	-1.20414505782449	52	22	0.0130331753554502	1688	4455	3280,7050,3397,2004,659,6929,5076,3398,467,4090,5710,7422,654,898,6934,4088,3399,890,1499,4086,5970,4089	HES1,TGIF1,ID1,ELK3,BMPR2,TCF3,PAX2,ID2,ATF3,SMAD5,PSMD4,VEGFA,BMP6,CCNE1,TCF7L2,SMAD3,ID3,CCNA2,CTNNB1,SMAD1,RELA,SMAD4
WP615	Senescence and Autophagy	0.315869200145921	-1.1524270746741	106	43	0.0254739336492891	1688	4455	3916,673,7405,2475,5894,5604,26156,8408,1026,81631,8678,27173,55626,5606,3490,7057,4193,5111,8878,11337,3572,1027,4297,3486,64223,22863,3621,9821,8804,9140,51100,3663,4088,2934,3569,2932,3159,9474,5594,3265,4089,1029,3659	LAMP1,BRAF,UVRAG,MTOR,RAF1,MAP2K1,RSL1D1,ULK1,CDKN1A,MAP1LC3B,BECN1,SLC39A1,AMBRA1,MAP2K3,IGFBP7,THBS1,MDM2,PCNA,SQSTM1,GABARAP,IL6ST,CDKN1B,KMT2A,IGFBP3,MLST8,ATG14,ING1,RB1CC1,CREG1,ATG12,SH3GLB1,IRF5,SMAD3,GSN,IL6,GSK3B,HMGA1,ATG5,MAPK1,HRAS,SMAD4,CDKN2A,IRF1
WP2516	ATM Signaling Pathway	0.321863669703648	-1.13362720910441	3	2	0.00118483412322275	1688	4455	1647,891	GADD45A,CCNB1
WP524	G13 Signaling Pathway	0.326407134111246	-1.11960979917257	40	17	0.0100710900473934	1688	4455	10188,387,11113,8826,5879,808,1729,1073,3984,8976,5296,9138,5500,6198,6093,10672,9475	TNK2,RHOA,CIT,IQGAP1,RAC1,CALM3,DIAPH1,CFL2,LIMK1,WASL,PIK3R2,ARHGEF1,PPP1CB,RPS6KB1,ROCK1,GNA13,ROCK2
WP497	Urea cycle and metabolism of amino groups	0.330020108926455	-1.10860169023737	20	9	0.00533175355450237	1688	4455	6723,1373,65263,435,1152,5832,4942,4953,5831	SRM,CPS1,PYCRL,ASL,CKB,ALDH18A1,OAT,ODC1,PYCR1
WP170	Nuclear Receptors	0.351628517679526	-1.04518000815667	38	16	0.00947867298578199	1688	4455	5915,7068,5914,2908,5468,3164,6256,5465,2100,7376,7025,6257,5467,2101,7026,5916	RARB,THRB,RARA,NR3C1,PPARG,NR4A1,RXRA,PPARA,ESR2,NR1H2,NR2F1,RXRB,PPARD,ESRRA,NR2F2,RARG
WP2338	miRNA Biogenesis	0.378900112232953	-0.970482664750307	1	1	0.000592417061611374	1688	4455	5901	RAN
WP1946	Cori Cycle	0.378900112232953	-0.970482664750307	1	1	0.000592417061611374	1688	4455	3098	HK1
WP1584	Type II diabetes mellitus	0.396974522325919	-0.923883175855745	21	9	0.00533175355450237	1688	4455	5599,2710,6517,3643,2475,3551,5590,3767,5594	MAPK8,GK,SLC2A4,INSR,MTOR,IKBKB,PRKCZ,KCNJ11,MAPK1
WP368	Mitochondrial LC-Fatty Acid Beta-Oxidation	0.403287914404205	-0.908104544315515	16	7	0.00414691943127962	1688	4455	6342,55825,2182,2180,1962,1632,2181	SCP2,PECR,ACSL4,ACSL1,EHHADH,ECI1,ACSL3
WP438	Non-homologous end joining	0.411970979914389	-0.886802369214418	6	3	0.00177725118483412	1688	4455	4361,79840,7520	MRE11A,NHEJ1,XRCC5
WP619	Type II interferon signaling (IFNG)	0.431013482046324	-0.841615908517686	50	20	0.0118483412322275	1688	4455	8367,6890,8368,8360,9636,6773,9021,8365,121504,8294,5610,8651,8366,8364,5781,3660,3717,3459,2537,3659	HIST1H4E,TAP1,HIST1H4L,HIST1H4D,ISG15,STAT2,SOCS3,HIST1H4H,HIST4H4,HIST1H4I,EIF2AK2,SOCS1,HIST1H4B,HIST1H4C,PTPN11,IRF2,JAK2,IFNGR1,IFI6,IRF1
WP408	Oxidative Stress	0.439863127708555	-0.82129167385284	32	13	0.00770142180094787	1688	4455	7296,847,1535,2729,3726,6648,4501,25828,2876,4780,10587,4257,6667	TXNRD1,CAT,CYBA,GCLC,JUNB,SOD2,MT1X,TXN2,GPX1,NFE2L2,TXNRD2,MGST1,SP1
WP186	Homologous recombination	0.448417511380464	-0.802030535512641	14	6	0.00355450236966825	1688	4455	4361,10714,5424,5888,5425,25788	MRE11A,POLD3,POLD1,RAD51,POLD2,RAD54B
WP733	Serotonin Receptor 2 and STAT3 Signaling	0.488076422640254	-0.717283281619068	4	2	0.00118483412322275	1688	4455	3717,6774	JAK2,STAT3
WP690	Polyol pathway	0.488076422640254	-0.717283281619068	4	2	0.00118483412322275	1688	4455	231,3795	AKR1B1,KHK
WP69	TCR Signaling Pathway	0.516111297128174	-0.661432844649909	89	34	0.0201421800947867	1688	4455	5599,3601,5966,5894,5604,28988,1147,1399,6464,3551,5296,5601,5781,9020,1386,5970,5170,207,4690,6654,5295,10892,5605,9308,5595,2885,5335,2534,1398,3569,3708,2185,5594,3265	MAPK8,IL15RA,REL,RAF1,MAP2K1,DBNL,CHUK,CRKL,SHC1,IKBKB,PIK3R2,MAPK9,PTPN11,MAP3K14,ATF2,RELA,PDPK1,AKT1,NCK1,SOS1,PIK3R1,MALT1,MAP2K2,CD83,MAPK3,GRB2,PLCG1,FYN,CRK,IL6,ITPR1,PTK2B,MAPK1,HRAS
WP1433	NOD pathway	0.531267375477081	-0.632489852497977	39	15	0.00888625592417062	1688	4455	10910,840,10392,3551,5879,842,14,3606,1147,3320,55914,639,841,10980,5970	SUGT1,CASP7,NOD1,IKBKB,RAC1,CASP9,AAMP,IL18,CHUK,HSP90AA1,ERBB2IP,PRDM1,CASP8,COPS6,RELA
WP1591	Heart Development	0.532299809495487	-0.630548396692862	47	18	0.0106635071090047	1688	4455	659,2626,7422,2296,2303,5308,23493,1499,2627,5781,6722,4776,657,2065,4086,5594,4089,7423	BMPR2,GATA4,VEGFA,FOXC1,FOXC2,PITX2,HEY2,CTNNB1,GATA6,PTPN11,SRF,NFATC4,BMPR1A,ERBB3,SMAD1,MAPK1,SMAD4,VEGFB
WP1310	Selenium	0.533490229956809	-0.628314521516153	7	3	0.00177725118483412	1688	4455	7296,10587,114112	TXNRD1,TXNRD2,TXNRD3
WP1272	Selenium	0.533490229956809	-0.628314521516153	7	3	0.00177725118483412	1688	4455	7296,10587,114112	TXNRD1,TXNRD2,TXNRD3
WP35	G Protein Signaling Pathways	0.53888448987129	-0.618254035545587	95	36	0.0213270142180095	1688	4455	10142,2785,2782,808,5566,2783,5581,10681,2781,9138,115,10270,5584,6548,5144,2771,11215,5567,387,6237,5141,11214,27115,2773,2767,2770,8165,2778,2768,3708,5590,5150,5533,10672,3265,11216	AKAP9,GNG3,GNB1,CALM3,PRKACA,GNB2,PRKCE,GNB5,GNAZ,ARHGEF1,ADCY9,AKAP8,PRKCI,SLC9A1,PDE4D,GNAI2,AKAP11,PRKACB,RHOA,RRAS,PDE4A,AKAP13,PDE7B,GNAI3,GNA11,GNAI1,AKAP1,GNAS,GNA12,ITPR1,PRKCZ,PDE7A,PPP3CC,GNA13,HRAS,AKAP10
WP241	One Carbon Metabolism	0.568221084465646	-0.565244702778417	29	11	0.00651658767772512	1688	4455	10797,10588,123263,471,7298,1719,6472,25902,23382,4522,4552	MTHFD2,MTHFS,MTFMT,ATIC,TYMS,DHFR,SHMT2,MTHFD1L,AHCYL2,MTHFD1,MTRR
WP2100	AhR pathway	0.568221084465646	-0.565244702778417	29	11	0.00651658767772512	1688	4455	3280,581,1027,3320,1026,10728,196,9049,4780,3727,1545	HES1,BAX,CDKN1B,HSP90AA1,CDKN1A,PTGES3,AHR,AIP,NFE2L2,JUND,CYP1B1
WP1422	Sphingolipid Metabolism	0.574339338582773	-0.554534875141972	21	8	0.004739336492891	1688	4455	2531,8611,253782,91012,427,8877,9517,56848	KDSR,PLPP1,CERS6,CERS5,ASAH1,SPHK1,SPTLC2,SPHK2
WP1495	Glycine Metabolism	0.614287766145264	-0.487291786124899	2	1	0.000592417061611374	1688	4455	6472	SHMT2
WP311	Synthesis and Degradation of Ketone Bodies	0.625746837335504	-0.468809402881182	5	2	0.00118483412322275	1688	4455	38,3155	ACAT1,HMGCL
WP100	Glutathione metabolism	0.637289619395965	-0.450531065205083	22	8	0.004739336492891	1688	4455	26873,2729,2539,2952,3417,2876,2879,2937	OPLAH,GCLC,G6PD,GSTT1,IDH1,GPX1,GPX4,GSS
WP699	Aflatoxin B1 metabolism	0.639169358333496	-0.447585823204932	8	3	0.00177725118483412	1688	4455	2952,8574,2052	GSTT1,AKR7A2,EPHX1
WP2064	Neural Crest Differentiation	0.640494672739441	-0.445514475026634	101	37	0.0219194312796209	1688	4455	3397,54567,3975,6662,1488,83933,10013,2113,2637,23493,1499,6925,51564,4286,7020,4791,1856,6591,3280,4487,6615,5376,7976,8841,1857,6911,10014,388,2260,4488,9759,3688,3065,2932,3516,4086,3066	ID1,DLL4,LHX1,SOX9,CTBP2,HDAC10,HDAC6,ETS1,GBX2,HEY2,CTNNB1,TCF4,HDAC7,MITF,TFAP2A,NFKB2,DVL2,SNAI2,HES1,MSX1,SNAI1,PMP22,FZD3,HDAC3,DVL3,TBX6,HDAC5,RHOB,FGFR1,MSX2,HDAC4,ITGB1,HDAC1,GSK3B,RBPJ,SMAD1,HDAC2
WP560	TGF Beta Signaling Pathway	0.642276025274416	-0.442737121782129	55	20	0.0118483412322275	1688	4455	2033,7050,864,4090,9372,5595,7057,1387,4088,4087,1499,25805,7030,9241,5601,4086,6774,4091,3265,4089	EP300,TGIF1,RUNX3,SMAD5,ZFYVE9,MAPK3,THBS1,CREBBP,SMAD3,SMAD2,CTNNB1,BAMBI,TFE3,NOG,MAPK9,SMAD1,STAT3,SMAD6,HRAS,SMAD4
WP1423	Ganglio Sphingolipid Metabolism	0.651935884828381	-0.427809058043591	11	4	0.0023696682464455	1688	4455	6482,8705,2583,9197	ST3GAL1,B3GALT4,B4GALNT1,SLC33A1
WP143	Fatty Acid Beta Oxidation	0.68393333568505	-0.379894828558117	34	12	0.00710900473933649	1688	4455	2710,2180,1384,2181,1892,3032,38,1375,2182,2639,1632,7167	GK,ACSL1,CRAT,ACSL3,ECHS1,HADHB,ACAT1,CPT1B,ACSL4,GCDH,ECI1,TPI1
WP306	Focal Adhesion	0.689662996114612	-0.371552212130643	184	67	0.0396919431279621	1688	4455	5599,5753,5607,71,5894,5879,5604,2064,10420,5881,329,5606,7791,5906,6464,1289,5296,4637,7414,10188,207,330,208,87,857,2534,1398,3673,3688,2932,60,6093,5594,823,673,4659,30849,3693,10298,7057,7408,5601,5062,53918,896,3913,5598,9475,7423,5170,387,3915,6654,5295,5908,3678,5747,9564,5605,388,2885,29780,7060,5608,5597,3685,1288	MAPK8,PTK6,MAP2K5,ACTG1,RAF1,RAC1,MAP2K1,ERBB2,TESK2,RAC3,BIRC2,MAP2K3,ZYX,RAP1A,SHC1,COL5A1,PIK3R2,MYL6,VCL,TNK2,AKT1,BIRC3,AKT2,ACTN1,CAV1,FYN,CRK,ITGA2,ITGB1,GSK3B,ACTB,ROCK1,MAPK1,CAPN1,BRAF,PPP1R12A,PIK3R4,ITGB5,PAK4,THBS1,VASP,MAPK9,PAK2,PELO,CCND3,LAMB2,MAPK7,ROCK2,VEGFB,PDPK1,RHOA,LAMC1,SOS1,PIK3R1,RAP1B,ITGA5,PTK2,BCAR1,MAP2K2,RHOB,GRB2,PARVB,THBS4,MAP2K6,MAPK6,ITGAV,COL4A6
WP1539	Angiogenesis	0.694626963672684	-0.364380320432391	23	8	0.004739336492891	1688	4455	1387,5335,5747,207,4086,7422,5594,3091	CREBBP,PLCG1,PTK2,AKT1,SMAD1,VEGFA,MAPK1,HIF1A
WP666	Hypothetical Network for Drug Addiction	0.720214468737474	-0.328206238080972	32	11	0.00651658767772512	1688	4455	54386,5581,22882,375519,5604,814,5594,5566,5605,5595,889	TERF2IP,PRKCE,ZHX2,GJB7,MAP2K1,CAMK4,MAPK1,PRKACA,MAP2K2,MAPK3,KRIT1
WP696	Benzo(a)pyrene metabolism	0.726684762750232	-0.319262509309891	9	3	0.00177725118483412	1688	4455	10327,1545,2052	AKR1A1,CYP1B1,EPHX1
WP2007	Iron metabolism in placenta	0.727335744379833	-0.318367086350031	12	4	0.0023696682464455	1688	4455	4891,2495,3658,7037	SLC11A2,FTH1,IREB2,TFRC
WP106	Alanine and aspartate metabolism	0.727335744379833	-0.318367086350031	12	4	0.0023696682464455	1688	4455	5091,2571,2806,435	PC,GAD1,GOT2,ASL
WP2118	Arrhythmogenic right ventricular cardiomyopathy	0.728093211036419	-0.317326201843568	74	26	0.0154028436018957	1688	4455	3728,71,1495,59285,3678,5318,87,785,1832,3693,1605,6934,4000,59283,2010,488,1499,783,1829,3673,3688,81,60,784,3685,781	JUP,ACTG1,CTNNA1,CACNG6,ITGA5,PKP2,ACTN1,CACNB4,DSP,ITGB5,DAG1,TCF7L2,LMNA,CACNG8,EMD,ATP2A2,CTNNB1,CACNB2,DSG2,ITGA2,ITGB1,ACTN4,ACTB,CACNB3,ITGAV,CACNA2D1
WP289	Myometrial Relaxation and Contraction Pathways	0.760992358837286	-0.273131962120552	155	55	0.0325829383886256	1688	4455	6004,1388,71,2785,8601,808,2782,2870,10488,3709,5997,7531,5566,2783,2553,5581,466,10681,488,5998,115,59,8490,5144,1386,5567,6667,3486,468,2551,10287,10971,467,3710,7532,133,2778,817,5335,2114,3569,59345,3708,6001,5590,27297,60,7534,784,7533,409,23764,5569,5570,2810	RGS16,ATF6B,ACTG1,GNG3,RGS20,CALM3,GNB1,GRK6,CREB3,ITPR2,RGS2,YWHAE,PRKACA,GNB2,GABPB1,PRKCE,ATF1,GNB5,ATP2A2,RGS3,ADCY9,ACTA2,RGS5,PDE4D,ATF2,PRKACB,SP1,IGFBP3,ATF4,GABPA,RGS19,YWHAQ,ATF3,ITPR3,YWHAG,ADM,GNAS,CAMK2D,PLCG1,ETS2,IL6,GNB4,ITPR1,RGS10,PRKCZ,CRCP,ACTB,YWHAZ,CACNB3,YWHAH,ARRB2,MAFF,PKIA,PKIB,SFN
WP1991	SRF and miRs in Smooth Muscle Differentiation and Proliferation	0.78719342066161	-0.239281291178398	19	6	0.00355450236966825	1688	4455	6722,100271849,4205,817,4209,9314	SRF,MEF2B,MEF2A,CAMK2D,MEF2D,KLF4
WP12	Osteoclast Signaling	0.78729335913109	-0.239154343818919	16	5	0.00296208530805687	1688	4455	5599,6548,3454,7965,9550	MAPK8,SLC9A1,IFNAR1,AIMP2,ATP6V1G1
WP2291	Deregulation of Rab and Rab Effector Genes in Bladder Cancer	0.78729335913109	-0.239154343818919	16	5	0.00296208530805687	1688	4455	23086,9648,5874,83874,8567	EXPH5,GCC2,RAB27B,TBC1D10A,MADD
WP3	Keap1-Nrf2 Pathway	0.789764497476221	-0.236020482423516	13	4	0.0023696682464455	1688	4455	5599,7965,2729,4780	MAPK8,AIMP2,GCLC,NFE2L2
WP2333	Trans-sulfuration pathway	0.796560422550289	-0.227452292433571	10	3	0.00177725118483412	1688	4455	51380,4357,1491	CSAD,MPST,CTH
WP2113	Type III interferon signaling	0.796560422550289	-0.227452292433571	10	3	0.00177725118483412	1688	4455	3588,7297,6773	IL10RB,TYK2,STAT2
WP136	Phase I, non P450	0.812292580499829	-0.207894682907817	7	2	0.00118483412322275	1688	4455	5445,2098	PON2,ESD
WP465	Tryptophan metabolism	0.813864847300438	-0.205960962022423	46	15	0.00888625592417062	1688	4455	847,4193,7337,51166,8942,1892,3028,3276,38,2639,125061,51366,224,223,1545	CAT,MDM2,UBE3A,AADAT,KYNU,ECHS1,HSD17B10,PRMT1,ACAT1,GCDH,AFMID,UBR5,ALDH3A2,ALDH9A1,CYP1B1
WP75	Toll-like receptor signaling pathway	0.823586578798356	-0.194086599737924	103	35	0.0207345971563981	1688	4455	5599,5879,5604,1147,3661,5606,3592,51135,5296,5601,3551,8503,841,4791,5970,100302736,29110,207,5609,208,5295,958,3454,10333,5605,3663,5595,23118,5608,3569,148022,10454,5594,6416,114609	MAPK8,RAC1,MAP2K1,CHUK,IRF3,MAP2K3,IL12A,IRAK4,PIK3R2,MAPK9,IKBKB,PIK3R3,CASP8,NFKB2,RELA,TMED7-TICAM2,TBK1,AKT1,MAP2K7,AKT2,PIK3R1,CD40,IFNAR1,TLR6,MAP2K2,IRF5,MAPK3,TAB2,MAP2K6,IL6,TICAM1,TAB1,MAPK1,MAP2K4,TIRAP
WP34	Ovarian Infertility Genes	0.831121162152699	-0.184979691923723	32	10	0.00592417061611374	1688	4455	4088,1958,23224,1027,11144,9611,7784,2100,8204,2661	SMAD3,EGR1,SYNE2,CDKN1B,DMC1,NCOR1,ZP3,ESR2,NRIP1,GDF9
WP1603	Nicotine Activity on Chromaffin Cells	0.851307611619581	-0.160981744960265	4	1	0.000592417061611374	1688	4455	8913	CACNA1G
WP1449	Regulation of toll-like receptor signaling pathway	0.85637727448406	-0.155044258718581	102	34	0.0201421800947867	1688	4455	5599,5879,5604,1147,3661,5606,3592,3551,5296,5601,51135,8503,4791,841,5970,64223,29110,5609,207,208,5295,958,3454,10333,5605,3663,5595,3569,5608,148022,10454,5594,6416,114609	MAPK8,RAC1,MAP2K1,CHUK,IRF3,MAP2K3,IL12A,IKBKB,PIK3R2,MAPK9,IRAK4,PIK3R3,NFKB2,CASP8,RELA,MLST8,TBK1,MAP2K7,AKT1,AKT2,PIK3R1,CD40,IFNAR1,TLR6,MAP2K2,IRF5,MAPK3,IL6,MAP2K6,TICAM1,TAB1,MAPK1,MAP2K4,TIRAP
WP1531	Vitamin D synthesis	0.870000321222366	-0.139261698112465	8	2	0.00118483412322275	1688	4455	1591,6256	CYP24A1,RXRA
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy	0.879968354913354	-0.127869332482206	15	4	0.0023696682464455	1688	4455	207,6774,208,5534	AKT1,STAT3,AKT2,PPP3R1
WP536	Calcium Regulation in the Cardiac Cell	0.915142330098335	-0.0886756737835386	149	49	0.0290284360189573	1688	4455	6004,309,2785,8536,8601,808,814,2782,3709,2870,5997,7531,5566,2783,5581,811,10681,488,2781,5998,115,2707,8490,2771,5567,10287,10971,154,481,3710,2773,2767,7532,2770,10052,2778,817,59345,3708,6001,5590,482,7534,784,409,7533,5569,5570,2810	RGS16,ANXA6,GNG3,CAMK1,RGS20,CALM3,CAMK4,GNB1,ITPR2,GRK6,RGS2,YWHAE,PRKACA,GNB2,PRKCE,CALR,GNB5,ATP2A2,GNAZ,RGS3,ADCY9,GJB3,RGS5,GNAI2,PRKACB,RGS19,YWHAQ,ADRB2,ATP1B1,ITPR3,GNAI3,GNA11,YWHAG,GNAI1,GJC1,GNAS,CAMK2D,GNB4,ITPR1,RGS10,PRKCZ,ATP1B2,YWHAZ,CACNB3,ARRB2,YWHAH,PKIA,PKIB,SFN
WP2267	Synaptic Vesicle Pathway	0.921405048873768	-0.0818555469275365	51	15	0.00888625592417062	1688	4455	1173,26052,291,8218,81539,160,1213,1785,163,6855,6616,8775,6857,1175,11315	AP2M1,DNM3,SLC25A4,CLTCL1,SLC38A1,AP2A1,CLTC,DNM2,AP2B1,SYP,SNAP25,NAPA,SYT1,AP2S1,PARK7
WP167	Eicosanoid Synthesis	0.926464355649389	-0.0763797060427821	20	5	0.00296208530805687	1688	4455	5743,50640,9536,8398,6916	PTGS2,PNPLA8,PTGES,PLA2G6,TBXAS1
WP98	Prostaglandin Synthesis and Regulation	0.931103909035805	-0.071384397797889	30	8	0.004739336492891	1688	4455	308,5743,302,309,3291,307,5734,6916	ANXA5,PTGS2,ANXA2,ANXA6,HSD11B2,ANXA4,PTGER4,TBXAS1
WP176	Folate Metabolism	0.93923188306501	-0.0626928834391246	24	6	0.00355450236966825	1688	4455	847,4791,5970,2876,2879,4552	CAT,NFKB2,RELA,GPX1,GPX4,MTRR
WP1602	Nicotine Activity on Dopaminergic Neurons	0.944980857337463	-0.0565906084793197	21	5	0.00296208530805687	1688	4455	2782,5499,1138,5566,2770	GNB1,PPP1CA,CHRNA5,PRKACA,GNAI1
WP1038	Vitamin A and Carotenoid Metabolism	0.953961185467983	-0.0471322944538128	25	6	0.00355450236966825	1688	4455	5915,5914,5916,1592,6256,6257	RARB,RARA,RARG,CYP26A1,RXRA,RXRB
WP1001	Peptide GPCRs	0.959266601634283	-0.0415862431147851	11	2	0.00118483412322275	1688	4455	4987,6869	OPRL1,TACR1
WP2012	miRs in Muscle Cell Differentiation	0.961246324172958	-0.0395245821769208	42	11	0.00651658767772512	1688	4455	5581,5584,5590,6722,100271849,3398,4205,4209,5566,5567,2146	PRKCE,PRKCI,PRKCZ,SRF,MEF2B,ID2,MEF2A,MEF2D,PRKACA,PRKACB,EZH2
WP501	GPCRs, Class C Metabotropic glutamate, pheromone	0.961368351213847	-0.0393976435421383	15	3	0.00177725118483412	1688	4455	55890,2918,2550	GPRC5C,GRM8,GABBR1
WP694	Arylamine metabolism	0.96444671845408	-0.0362006908226481	7	1	0.000592417061611374	1688	4455	9	NAT1
WP678	Arachidonate Epoxygenase / Epoxide Hydrolase	0.96444671845408	-0.0362006908226481	7	1	0.000592417061611374	1688	4455	1351	COX8A
WP698	Glucuronidation	0.965382213402935	-0.0352311799953527	26	6	0.00355450236966825	1688	4455	5236,3098,55276,7360,7358,5238	PGM1,HK1,PGM2,UGP2,UGDH,PGM3
WP474	Endochondral Ossification	0.969103636261288	-0.0313837210442683	65	18	0.0106635071090047	1688	4455	50515,207,1028,579,6662,5727,808,864,6777,7422,5566,654,2260,2737,3157,9759,11127,657	CHST11,AKT1,CDKN1C,NKX3-2,SOX9,PTCH1,CALM3,RUNX3,STAT5B,VEGFA,PRKACA,BMP6,FGFR1,GLI3,HMGCS1,HDAC4,KIF3A,BMPR1A
WP195	IL-1 Signaling Pathway	0.972730405140437	-0.0276483110978627	12	2	0.00118483412322275	1688	4455	3556,51135	IL1RAP,IRAK4
WP2197	Endothelin	0.975367815613653	-0.0249406323407332	34	8	0.004739336492891	1688	4455	2778,808,10681,488,5594,5894,5604,2770	GNAS,CALM3,GNB5,ATP2A2,MAPK1,RAF1,MAP2K1,GNAI1
WP2276	Glial Cell Differentiation	0.977939060916716	-0.0223079207897708	8	1	0.000592417061611374	1688	4455	1267	CNP
WP237	Glucocorticoid & Mineralcorticoid Metabolism	0.977939060916716	-0.0223079207897708	8	1	0.000592417061611374	1688	4455	3291	HSD11B2
WP706	SIDS Susceptibility Pathways	0.979088367134399	-0.0211333778750048	160	49	0.0290284360189573	1688	4455	2033,836,4824,1958,6929,5087,10664,7531,5566,7259,1390,1387,6869,1499,2624,6711,3032,4904,3329,4791,4150,23171,5316,5567,6667,7068,6670,3280,10522,2597,2908,54862,10971,864,6616,2100,7422,7532,291,3091,3569,55536,226,3065,7534,1746,10891,30012,7533	EP300,CASP3,NKX3-1,EGR1,TCF3,PBX1,CTCF,YWHAE,PRKACA,TSPYL1,CREM,CREBBP,TACR1,CTNNB1,GATA2,SPTBN1,HADHB,YBX1,HSPD1,NFKB2,MAZ,GPD1L,PKNOX1,PRKACB,SP1,THRB,SP3,HES1,DEAF1,GAPDH,NR3C1,CC2D1A,YWHAQ,RUNX3,SNAP25,ESR2,VEGFA,YWHAG,SLC25A4,HIF1A,IL6,CDCA7L,ALDOA,HDAC1,YWHAZ,DLX2,PPARGC1A,TLX3,YWHAH
WP299	Nuclear receptors in lipid metabolism and toxicity	0.981255974100062	-0.0189219216492124	35	8	0.004739336492891	1688	4455	1591,5915,5467,5914,5468,5916,1592,5465	CYP24A1,RARB,PPARD,RARA,PPARG,RARG,CYP26A1,PPARA
WP2436	Dopamine metabolism	0.981844567873666	-0.0183222643431734	13	2	0.00118483412322275	1688	4455	5566,5567	PRKACA,PRKACB
WP229	Irinotecan Pathway	0.981844567873666	-0.0183222643431734	13	2	0.00118483412322275	1688	4455	324,9429	APC,ABCG2
WP15	Selenium Pathway	0.984297094468832	-0.015827502226943	87	24	0.014218009478673	1688	4455	7296,55163,85465,83642,1734,6648,6414,9403,280636,114112,847,80308,5743,3643,3569,8942,51714,4791,5970,2876,57190,10587,2879,1491	TXNRD1,PNPO,EPT1,SELO,DIO2,SOD2,SEPP1,SEP15,C11orf31,TXNRD3,CAT,FLAD1,PTGS2,INSR,IL6,KYNU,SELT,NFKB2,RELA,GPX1,SEPN1,TXNRD2,GPX4,CTH
WP716	Vitamin A and carotenoid metabolism	0.987894711704352	-0.0121791540138046	40	9	0.00533175355450237	1688	4455	5915,54884,5914,6256,9249,116362,5916,1592,6257	RARB,RETSAT,RARA,RXRA,DHRS3,RBP7,RARG,CYP26A1,RXRB
WP1533	Vitamin B12 Metabolism	0.991152837581205	-0.00888653093198527	19	3	0.00177725118483412	1688	4455	4791,5970,4552	NFKB2,RELA,MTRR
WP496	Steroid Biosynthesis	0.991509497987124	-0.00852675165604138	10	1	0.000592417061611374	1688	4455	3295	HSD17B4
WP1455	Serotonin Transporter Activity	0.991509497987124	-0.00852675165604138	10	1	0.000592417061611374	1688	4455	7041	TGFB1I1
WP383	Striated Muscle Contraction	0.992012660935275	-0.00801940873911902	38	8	0.004739336492891	1688	4455	59,81,10398,7169,7170,7168,71,7171	ACTA2,ACTN4,MYL9,TPM2,TPM3,TPM1,ACTG1,TPM4
WP430	Statin Pathway	0.994523269175959	-0.00549178309762408	32	6	0.00355450236966825	1688	4455	3931,8694,5360,2222,3156,4035	LCAT,DGAT1,PLTP,FDFT1,HMGCR,LRP1
WP80	Nucleotide GPCRs	0.994733787618911	-0.00528012775321425	11	1	0.000592417061611374	1688	4455	5029	P2RY2
WP2431	Spinal Cord Injury	0.995445853311196	-0.00456454840748507	112	30	0.0177725118483412	1688	4455	4282,836,387,50515,3958,328,1958,3164,7832,5786,389,1875,5879,6662,57142,900,2920,983,2309,388,5595,6869,1647,3569,961,1027,5594,8398,9475,9353	MIF,CASP3,RHOA,CHST11,LGALS3,APEX1,EGR1,NR4A1,BTG2,PTPRA,RHOC,E2F5,RAC1,SOX9,RTN4,CCNG1,CXCL2,CDK1,FOXO3,RHOB,MAPK3,TACR1,GADD45A,IL6,CD47,CDKN1B,MAPK1,PLA2G6,ROCK2,SLIT2
WP545	Complement Activation, Classical Pathway	0.99658241617601	-0.00342343710344042	17	2	0.00118483412322275	1688	4455	715,717	C1R,C2
WP554	ACE Inhibitor Pathway	0.99658241617601	-0.00342343710344042	17	2	0.00118483412322275	1688	4455	4306,10159	NR3C2,ATP6AP2
WP692	Sulfation Biotransformation Reaction	0.997767882196746	-0.00223461269147892	18	2	0.00118483412322275	1688	4455	2539,9061	G6PD,PAPSS1
WP322	Osteoblast Signaling	0.997974889066359	-0.00202716424337637	13	1	0.000592417061611374	1688	4455	3685	ITGAV
WP550	Biogenic Amine Synthesis	0.999221677420326	-0.00077862562995078	15	1	0.000592417061611374	1688	4455	2571	GAD1
WP453	Inflammatory Response Pathway	0.999334468787526	-0.000665752776682433	30	4	0.0023696682464455	1688	4455	3913,958,3915,7057	LAMB2,CD40,LAMC1,THBS1
WP697	Estrogen metabolism	0.999701028005421	-0.000299016695615222	17	1	0.000592417061611374	1688	4455	1545	CYP1B1
WP530	Cytokines and Inflammatory Response	0.99974424266183	-0.000255790049655754	23	2	0.00118483412322275	1688	4455	2920,3569	CXCL2,IL6
WP43	cytochrome P450	0.999850416872296	-0.000149594316375319	62	11	0.00651658767772512	1688	4455	1591,10858,29785,51167,113612,80777,51302,1592,1528,1727,1545	CYP24A1,CYP46A1,CYP2S1,CYB5R4,CYP2U1,CYB5B,CYP39A1,CYP26A1,CYB5A,CYB5R3,CYP1B1
WP691	Tamoxifen metabolism	0.999885221350474	-0.000114785237099353	19	1	0.000592417061611374	1688	4455	1545	CYP1B1
WP247	Small Ligand GPCRs	0.999885221350474	-0.000114785237099353	19	1	0.000592417061611374	1688	4455	5734	PTGER4
WP727	Monoamine Transport	0.999952969804094	-4.70313018608319e-05	32	3	0.00177725118483412	1688	4455	7249,995,7041	TSC2,CDC25C,TGFB1I1
WP58	Monoamine GPCRs	0.999969121024926	-3.08794518397123e-05	33	3	0.00177725118483412	1688	4455	154,151,3269	ADRB2,ADRA2B,HRH1
WP2328	Allograft Rejection	0.999971408848532	-2.85915602026906e-05	38	4	0.0023696682464455	1688	4455	3592,958,100507436,3105	IL12A,CD40,MICA,HLA-A
WP129	Matrix Metalloproteinases	0.999992692252384	-7.30777431738666e-06	31	2	0.00118483412322275	1688	4455	682,4324	BSG,MMP15
WP702	metapathway biotransformation	0.999999501805843	-4.98194281410639e-07	181	39	0.0231042654028436	1688	4455	57106,1591,50515,79829,10858,55226,2952,113189,4258,51302,1592,9435,2937,373156,55501,29785,80218,231,8574,2879,1545,2052,2954,8509,4259,2948,79807,122830,4257,10327,119391,9,9469,113612,9953,51126,7172,9653,266722	NAT14,CYP24A1,CHST11,NAA40,CYP46A1,NAT10,GSTT1,CHST14,MGST2,CYP39A1,CYP26A1,CHST2,GSS,GSTK1,CHST12,CYP2S1,NAA50,AKR1B1,AKR7A2,GPX4,CYP1B1,EPHX1,GSTZ1,NDST2,MGST3,GSTM4,GSTCD,NAA30,MGST1,AKR1A1,GSTO2,NAT1,CHST3,CYP2U1,HS3ST3B1,NAA20,TPMT,HS2ST1,HS6ST3
WP2406	Cardiac Progenitor Differentiation	0.999999552376578	-4.47623521971129e-07	53	5	0.00296208530805687	1688	4455	2932,7852,2626,9241,22943	GSK3B,CXCR4,GATA4,NOG,DKK1
WP1545	miRNAs involved in DDR	0.999999941426788	-5.85732140652725e-08	72	8	0.004739336492891	1688	4455	25,1027,993,1026,1021,898,896,3014	ABL1,CDKN1B,CDC25A,CDKN1A,CDK6,CCNE1,CCND3,H2AFX
WP558	Complement and Coagulation Cascades	0.999999987621686	-1.23783139322016e-08	51	3	0.00177725118483412	1688	4455	715,717,2152	C1R,C2,F3
WP24	Peptide GPCRs	0.999999999877939	-1.22060854493551e-10	72	5	0.00296208530805687	1688	4455	4987,7852,6869,4157,10396	OPRL1,CXCR4,TACR1,MC1R,ATP8A1
WP455	GPCRs, Class A Rhodopsin-like	0.999999999922295	-7.77048247967053e-11	257	14	0.00829383886255924	1688	4455	81491,7852,4157,5734,23596,4987,2863,154,2852,151,2842,611,3269,5029	GPR63,CXCR4,MC1R,PTGER4,OPN3,OPRL1,GPR39,ADRB2,GPER1,ADRA2B,GPR19,OPN1SW,HRH1,P2RY2
WP2526	PDGF Pathway	0.999999999996058	-3.94212440468777e-12	2	0	0	1688	4455
WP1273	Folic Acid Network	0.999999999996058	-3.94212440468777e-12	2	0	0	1688	4455
WP1075	Folic Acid Network	0.999999999996058	-3.94212440468777e-12	2	0	0	1688	4455
WP1311	Folic Acid Network	0.999999999996058	-3.94212440468777e-12	2	0	0	1688	4455
WP688	Catalytic cycle of mammalian FMOs	0.999999999998988	-1.01178614098085e-12	5	0	0	1688	4455
WP1589	Folate-Alcohol and Cancer Pathway	0.999999999998988	-1.01178614098085e-12	5	0	0	1688	4455
WP521	Amino acid conjugation of benzoic acid	1.00000000000024	2.40019809583103e-13	4	0	0	1688	4455
WP1995	Effects of nitric oxide	1.00000000000024	2.40019809583103e-13	4	0	0	1688	4455
WP1438	Influenza A virus infection	1.00000000000029	2.93653990013354e-13	1	0	0	1688	4455
WP1	Statin Pathway	1.00000000000029	2.93653990013354e-13	1	0	0	1688	4455
WP1006	metapathway biotransformation	1.00000000000029	2.93653990013354e-13	1	0	0	1688	4455
WP1604	Codeine and morphine metabolism	1.00000000001314	1.31423204567313e-11	8	0	0	1688	4455
WP117	GPCRs, Other	1.00000000001455	1.4553991227341e-11	91	5	0.00296208530805687	1688	4455	11245,154,1951,2918,27239	GPR176,ADRB2,CELSR3,GRM8,GPR162
WP1981	Thyroxine (Thyroid Hormone) Production	1.00000000001464	1.46361165374864e-11	6	0	0	1688	4455
WP1600	Nicotine metabolism	1.00000000001464	1.46361165374864e-11	6	0	0	1688	4455
WP206	Fatty Acid Omega Oxidation	1.0000000000251	2.50990209032813e-11	15	0	0	1688	4455
WP2289	Drug Induction of Bile Acid Pathway	1.0000000000274	2.74012027428578e-11	17	0	0	1688	4455
WP272	Blood Clotting Cascade	1.00000000003777	3.77740316088481e-11	24	0	0	1688	4455
WP334	GPCRs, Class B Secretin-like	1.00000000004031	4.03091691135047e-11	23	0	0	1688	4455